Clinical Trials Sponsored by Imperial College Health Partners

Total 156 results

Imperial College London
British Heart Foundation; Humboldt-Universität zu Berlin

Completed

Identifying an Ideal Cardiopulmonary Exercise Test Parameter (PVA)

Mitral Regurgitation | Left Ventricular Systolic Dysfunction

United Kingdom
Imperial College London
British Heart Foundation; Leducq Foundation; Celladon Corporation

Terminated

Investigation of the Safety and Feasibility of AAV1/SERCA2a Gene Transfer in Patients With Chronic Heart Failure (SERCA-LVAD)

Chronic Heart Failure | Patients That Have Received a Left Ventricular Assist Device

United Kingdom
Imperial College London
Wellcome Trust; National Institute for Health Research, United Kingdom

Completed

The Safety and Immunogenicity of a Potential HIV Vaccine

HIV Infections

United Kingdom
Imperial College Healthcare NHS Trust
National Institute for Health Research, United Kingdom

Completed

Low Dose Peri-operative IV Ketamine for Chronic Post-surgery Pain Prevention

Chronic Postoperative Pain

United Kingdom
Imperial College Healthcare NHS Trust
National Institute for Health Research, United Kingdom

Completed

Effects of Oral Sodium Bicarbonate Supplementation in Haemodialysis Patients (BicHD) (BicHD)

End-stage Renal Disease

United Kingdom
Imperial College London
National Institute for Health and Care Research; NHS-X

Not yet recruiting

AI Clinician XP2 - A Study of the AI Clinician Running in Real Time in the ICU

Sepsis

United Kingdom
Imperial College Healthcare NHS Trust
National Institute for Health Research, United Kingdom

Terminated

The Role of Ambulatory Oxygen in Improving the Effectiveness of Pulmonary Rehabilitation for COPD Patients

Chronic Obstructive Pulmonary Diseases

United Kingdom
University Hospital Southampton NHS Foundation...
Imperial College London; Public Health England

Completed

Safety of Nasal Influenza Immunisation in Egg Allergic Children (SNIFFLE)

Egg Hypersensitivity

United Kingdom
University Hospital Southampton NHS Foundation...
Imperial College London; Public Health England

Completed

Safety of Nasal Influenza Immunisation in Egg Allergic Children - The SNIFFLE 2 Study (SNIFFLE-2)

Egg Hypersensitivity

United Kingdom
Imperial College London
University College, London; Medical Research Council; National Institute for...

Recruiting

A Randomised Open-label Phase III Trial of REduced Frequency Pembrolizumab immuNothErapy for First-line Treatment of Patients With Advanced Non-small Cell Lung Cancer (NSCLC) (REFINE-Lung)

Lung Cancer, Nonsmall Cell

United Kingdom
Pedro A. Lemos
Imperial College London; Cardialysis B.V.

Unknown

Acetyl Salicylic Elimination Trial: The ASET Pilot Study (ASET)

Monotherapy After PCI

Brazil
Imperial College London
British Heart Foundation; Institut de Recherches Internationales Servier

Unknown

The Hypertension in the Very Elderly Trial (HYVET)

Hypertension

United Kingdom, Bulgaria, China, Finland, Romania, Russian Federation
Imperial College London
Medical Research Council; British Heart Foundation; Rosetrees Trust

Not yet recruiting

Artificial Intelligence Delivered Cardiac Magnetic Resonance - Prospective Validation (AID-MR)

Cardiovascular Diseases | Healthy Volunteers
Embody Orthopaedic Limited
Imperial College London; National Institute for Health Research, United Kingdom

Not yet recruiting

The ACTIVE Trial: A Prospective Randomised Control Trial Of The H1 Implant Versus Total Hip Replacement (ACTIVE)

Inflammatory Arthritis | Osteoarthritis, Hip
Imperial College London
University of Sydney; National Institute for Health Research, United Kingdom

Completed

Boiled Peanut Oral Immunotherapy for the Treatment of Peanut Allergy: a Pilot Study (BOPI-1)

IgE Mediated Peanut Allergy

United Kingdom
Queen Mary University of London
Imperial College London; Health Effects Institute; Asthma UK

Active, not recruiting

Assessing the Impact of Non-tailpipe Emissions From Traffic on the Asthmatic Airway (IONA)

Asthma

United Kingdom
University of Oxford
Imperial College London; Public Health England; Novartis Vaccines; European Commission

Completed

Investigating the Immune Response to 4CMenB in Infants

Meningitis

United Kingdom
Giovanna Fichera
Russell Sage College; Precision Valve Automation; St Peters Health Partners; Ann...

Not yet recruiting

Novel Splinting Technique Using 3D Models

Arthritis | Rheumatoid Arthritis | Scleroderma, Systemic | Scleroderma, Diffuse | Osteoarthritis Hand

United States
Imperial College London
UMC Utrecht; Dr. Reddy's Laboratories Limited; Royal College of Surgeons, Ireland and other collaborators

Completed

UMPIRE - Use of a Multidrug Pill In Reducing Cardiovascular Events (UMPIRE)

Cardiovascular Diseases

Australia, India, Ireland, Netherlands, United Kingdom
Imperial College London
Cancer Research UK; National Institute for Health Research, United Kingdom

Recruiting

Use of DRS Probe and Tracking for In-vivo Application

Gastrointestinal Cancer

United Kingdom
Imperial College London
Cancer Research UK; National Institute for Health Research, United Kingdom

Not yet recruiting

Imperial Prostate 7 - Prostate Assessment Using Comparative Interventions - Fast Mri and Image-fusion for Cancer (IP7-PACIFIC)

Neoplasms | Adenocarcinoma | Prostatic Neoplasms | Prostatic Diseases | Prostate Cancer
Medecins Sans Frontieres, Netherlands
Imperial College London; Ministry of Health, Republic of Uzbekistan

Unknown

Effectiveness of a Simplified Short Regimen for Multidrug Resistant Tuberculosis in Uzbekistan

Multidrug Resistant Tuberculosis

Uzbekistan
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; British Heart Foundation

Recruiting

Defining the Genetics, Biomarkers and Outcomes for Dilated Cardiomyopathy (Go-DCM)

Cardiovascular Diseases | Dilated Cardiomyopathy

United Kingdom
Belfast Health and Social Care Trust
Imperial College London; Trauma and Orthopaedics Research Charity

Not yet recruiting

Gait in Fixed Or Rotating Cementless Total Knee Arthroplasties (G-FORCE)

Knee Osteoarthritis | Total Knee Arthroplasty

United Kingdom
Imperial College London
AstraZeneca; Medical Research Council; National Institute for Health Research...

Completed

Neuropeptide Treatment for Hot Flushes During the Menopause (NK3R)

Menopausal Flushing

United Kingdom
Lawson Health Research Institute
Imperial College London; Queen's University; Northern Ontario School of Medicine

Completed

Efficacy Study of Panax Ginseng to Boost Antipsychotics Effects in Schizophrenia

Obesity | Schizophrenia | Schizoaffective Disorder | Insulin Resistance | Tardive Dyskinesia

Canada, United Kingdom
Cwm Taf University Health Board (NHS)
Cardiff University; Imperial College London; University of Oxford

Completed

Characterisation of the Immune Response to SARS-CoV-2 Infection / COVID-19 in Type 1 Diabetes

Diabetes Mellitus, Type 1 | SARS-CoV2 Infection

United Kingdom
University of California, Berkeley
Dartmouth College; Advocate Health Care; HealthCare Partners Institute for Applied...

Completed

Impact of Patient Activation and Engagement on Patient-Centered Outcomes of Care in ACOs (ACTIVATE)

Cardiovascular Disease | Diabetes

United States
Public Health England
Imperial College London; University College, London; Queen Mary University of... and other collaborators

Completed

Prognostic Value of Interferon Gamma Release Assays in Predicting Active Tuberculosis Among Individuals With, or at Risk of, Latent Tuberculosis Infection (PREDICT)

Latent Tuberculosis | Tuberculosis

United Kingdom
Imperial College London
Medical Research Council; Wellcome Trust; National Institute for Health Research...

Terminated

A Study of Protective Immunity Against RSV and Influenza in Experimental Human Challenge of Volunteers

Influenza, Human | Respiratory Syncytial Virus Infections

United Kingdom
Medicines Development for Global Health
Imperial College London; Phillip T. and Susan M. Ragon Foundation

Terminated

A Safety and Immunogenicity Study of 3 Doses of Opal Immunotherapy in HIV Infected People

HIV Infections

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; Imperial College London; National Institute for Health...

Completed

The Grown Up Peanut Immunotherapy Study (GUPI)

Peanut Allergy

United Kingdom
GlaxoSmithKline
Quintiles, Inc.; Imperial College London; Royal Free Hospital NHS Foundation... and other collaborators

Completed

A Study to Evaluate the Safety of GSK2398852 When Co-administered With GSK2315698 in Patients With Systemic Amyloidosis

Amyloidosis

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; National Institute for Health...

Completed

Intelligent Oxygen Therapy During Activities of Daily Living

Hypoxia | COPD | Hyperoxia

United Kingdom
Imperial College London
University of Southern California; Guy's and St Thomas' NHS Foundation Trust; Ipse... and other collaborators

Terminated

A Study to Assess the Ability of a Novel Endocrine Treatment for Breast Cancer, Irosustat, to Slow Down Cancer Growth (IPET)

Breast Neoplasms

United Kingdom
RAND
National Institute of Mental Health (NIMH); Brigham and Women's Hospital; University... and other collaborators

Active, not recruiting

Integrating a Stepped Care Model of Screening and Treatment for Depression Into Malawi's National HIV Care Delivery Platform (IC3D)

Depressive Disorder

Malawi
Imperial College London
King's College Hospital NHS Trust; University of Oxford; University of Southampton and other collaborators

Unknown

Evaluating Liraglutide in Alzheimer's Disease (ELAD)

Alzheimer's Disease

United Kingdom
Qatar University
Imperial College London; Hamad Medical Corporation; Aspetar; Supreme Council Of... and other collaborators

Completed

Adapted Cognitive Behavioral Approach to Addressing Overweight and Obesity Among Qatari Youth

Obesity

Qatar
Imperial College London
Royal Marsden NHS Foundation Trust; Chelsea and Westminster NHS Foundation... and other collaborators

Recruiting

COlorectal BReath Analysis (COBRA2)

Colorectal Cancer

United Kingdom
Imperial College London
University of Sheffield; Medical Research Council; University of Cambridge; National...

Active, not recruiting

Positioning Imatinib for Pulmonary Arterial Hypertension (PIPAH)

Pulmonary Arterial Hypertension

United Kingdom
Royal Tropical Institute
Imperial College London; World Health Organization; Medical Research Council... and other collaborators

Completed

Community-based Screening and Treatment of Malaria in Pregnancy: a Cluster-randomized Trial (COSMIC)

Small for Gestational Age (Disorder) | Malaria, Antepartum | Maternal Malaria During Pregnancy - Baby Not Yet Delivered

Benin, Burkina Faso, Gambia
Imperial College London
Cambridge University Hospitals NHS Foundation Trust; National Institute for... and other collaborators

Active, not recruiting

Transplant Antibody-Mediated Rejection: Guiding Effective Treatments (TAR:GET-1)

Kidney Transplant Rejection | Antibody-mediated Rejection

United Kingdom
Imperial College London
Chelsea and Westminster NHS Foundation Trust; National Heart and Lung Institute and other collaborators

Completed

Defining the Intestinal Microbiota in Premature Neonates

Necrotizing Enterocolitis | Premature Intestinal Microbiota | Late Onset Bloodstream Infection

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Imperial College London; British Lung Foundation; National Heart and Lung Institute

Completed

The Use of Inflammatory Markers to Guide Therapy in Children With Severe Asthma

Asthma

United Kingdom
London School of Hygiene and Tropical Medicine
Emory University; Imperial College London; Kenya Medical Research Institute; Kenya...

Completed

Impact of Alternative Treatment Strategies and Delivery Systems for Soil-transmitted Helminths in Kenya (TUMIKIA)

Helminthiasis | Disease Transmission, Infectious | Nematode Infection

Kenya
Royal Marsden NHS Foundation Trust
Imperial College London; Royal Brompton & Harefield NHS Foundation Trust; Institute... and other collaborators

Recruiting

AI & Radiomics for Stratification of Lung Nodules After Radically Treated Cancer (AI-SONAR)

Lung Cancer | Lung Metastases | Indeterminate Pulmonary Nodules | Second Primary Cancer

United Kingdom
Imperial College London
University Hospitals, Leicester; Medical University of Silesia; Royal Brompton... and other collaborators

Completed

Randomised Ischaemic Mitral Evaluation (RIME) Trial (RIME)

Coronary Artery Disease | Mitral Regurgitation

United Kingdom, Poland
University of Cambridge
Imperial College London; Cambridge University Hospitals NHS Foundation Trust; Wellcome Trust and other collaborators

Active, not recruiting

PET Imaging of Giant Cell and Takayasu Arteritis (PITA)

Giant Cell Arteritis | Takayasu Arteritis

United Kingdom
Imperial College London
National Heart Foundation, Australia; Royal Brompton & Harefield NHS Foundation... and other collaborators

Completed

Radial Artery Versus Saphenous Vein Patency (RSVP) Study (RSVP)

Coronary Arteriosclerosis

United Kingdom
Imperial College London
University Hospital Southampton NHS Foundation Trust; National Institute for... and other collaborators

Unknown

EndoBarrier TM Gastrointestinal Liner Diabetes Trial (EndoBarrier)

Diabetes | Overweight and Obesity

United Kingdom

Clinical Trials Sponsored by Imperial College Health Partners

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Gambia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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