Clinical Trials Sponsored by LifeMark Health Research Group

Total 202 results

Hamilton Health Sciences Corporation
Canadian Institutes of Health Research (CIHR); Canadian Critical Care Trials...

Completed

PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT Pilot)

Critically Ill | Deep Venous Thrombosis

Canada, Australia
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Recruiting

Full-Time Occlusion Therapy for Intermittent Exotropia in Children (IXT7)

Intermittent Exotropia

United States
Canadian Medical and Surgical Knowledge Translation...
Unity Health Toronto; Western University, Canada

Completed

The Role of South Asian vs European Origins on Circulating Regenerative Cell Exhaustion (ORIGINS-RCE)

Cardiovascular Diseases | Diabetes | Ischemic Stroke | Peripheral Vascular Diseases | Type 1 Diabetes | Type 2 Diabetes | Ischemic Heart Disease

Canada
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Trial of Overminus Spectacle Therapy for Intermittent Exotropia (IXT5)

Intermittent Exotropia

United States, Canada
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Hyperopia Treatment Study 1 (HTS1) - Glasses vs Observation (HTS1)

Hyperopia

United States
Canadian Medical and Surgical Knowledge Translation...
Unity Health Toronto; Western University, Canada

Recruiting

Semaglutide and Vascular Regeneration (SEMA-VR)

Cardiovascular Diseases | Obesity | Diabetes Mellitus, Type 2 | Atherosclerosis

Canada
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Not yet recruiting

Bifocal Spectacles vs. Single Vision Spectacles for Esotropia Greater at Near (ETS3)

Esotropia
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Recruiting

Bevacizumab Treatment For Type 1 ROP (ROP4)

Retinopathy of Prematurity

United States, Canada
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Bilateral Lateral Rectus Recession Versus Unilateral Recess-Resect for Intermittent Exotropia (IXT1)

Exotropia

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Terminated

A Randomized Trial of Low-Dose Bevacizumab vs Laser for Type 1 ROP (ROP3)

Retinopathy of Prematurity

United States, Canada
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Base-in Prism Spectacles for Intermittent Exotropia (IXT6)

Exotropia Intermittent

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Low-Dose Atropine for Treatment of Myopia (MTS1)

Myopia

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Phase 1 Trial of Bevacizumab Treatment for Severe Retinopathy of Prematurity (ROP1)

Retinopathy of Prematurity

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Withdrawn

Excimer Laser Surgery for Anisometropic Amblyopia (ATS19)

Refractive Errors | Anisometropic Amblyopia
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Convergence Insufficiency Treatment Study (CITS)

Convergence Insufficiency

United States
McMaster University
National Health and Medical Research Council, Australia; Canadian Institutes... and other collaborators

Completed

Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial (REVISE)

Gastrointestinal Hemorrhage (Clinically Important, Upper)

Canada, Australia, United States, Brazil, Kuwait, Pakistan, Saudi Arabia, United Kingdom
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Not yet recruiting

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age (ATS23)

Amblyopia
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Recruiting

A Randomized Trial to Evaluate Sequential vs Simultaneous Patching (ATS22)

Amblyopia

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

A Prospective Observational Study of Adult Strabismus (SAS1)

Convergence Insufficiency | Divergence Insufficiency | Hypertropia

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Binocular Dig Rush Game Treatment for Amblyopia (ATS20)

Amblyopia

United States, Canada
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Observation Versus Occlusion Therapy for Intermittent Exotropia (IXT2)

Exotropia

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Study of Binocular Computer Activities for Treatment of Amblyopia (ATS18)

Amblyopia

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

A Pilot Clinical Trial of Overminus Spectacle Therapy for Intermittent Exotropia (IXT3)

Intermittent Exotropia

United States
Beauty Health
Callender Center for Clinical Research; ATS Clinical Research; Skin Surgery Medical... and other collaborators

Completed

Keravive by Hydrafacial for Scalp Health and Enhanced Hair Quality

Androgenic Alopecia

United States
Harvard School of Public Health (HSPH)
International Initiative for Impact Evaluation; Uganda Health Marketing Group; International Research Consortium

Completed

Impact of HIV Self-testing Among Female Sex Workers in Kampala, Uganda (HSPOT)

HIV Infection
Thunder Bay Regional Health Research Institute
Lakehead University; St. Joseph's Care Group; Thunder Bay Regional Health Sciences...

Recruiting

Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders

Bronchiectasis | Chronic Obstructive Pulmonary Disease | Asthma | Obstructive Sleep Apnea | Emphysema | Pulmonary Fibrosis | Lung Cancer | Cystic Fibrosis | Mesothelioma | Pulmonary Hypertension | Interstitial Lung Disease | Pulmonary Embolism | Lung Resection | Lung Transplant | Seasonal Allergies | Lung Infection | Asbes... and other conditions

Canada
Lawson Health Research Institute
Ontario Ministry of Health and Long Term Care; St. Joseph's Health Care London and other collaborators

Completed

Transition Into Primary-care Psychiatry (TIPP)

Mental Disorders

Canada
Pharnext S.C.A.
Premier Research Group plc; Eurofins Optimed; Synteract HCR (Syneos Health); Gr... and other collaborators

Active, not recruiting

Assessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1A (PLEO-CMT-FU)

Charcot-Marie-Tooth Disease, Type IA

United States, Belgium, Canada, France, Netherlands, Spain, United Kingdom
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Getinge...

Completed

Early Initiation of Extracorporeal Life Support in Refractory OHCA (INCEPTION)

Cardiac Arrest | Sudden Cardiac Death | Out-Of-Hospital Cardiac Arrest

Netherlands
Canadian Critical Care Trials Group
Bayer; Canadian Institutes of Health Research (CIHR); AstraZeneca; Queen's University

Completed

Study of Knowledge Translation of Clinical Practice Guidelines for Ventilator Associated Pneumonia (ABATEVAP)

Ventilator Associated Pneumonia

Canada, United States
The University of Texas Health Science Center at...
National Institute of Mental Health (NIMH); Vanguard Research Group

Active, not recruiting

Cognitive Adaption Training-Effectiveness in Real-world Settings and Mechanism of Action (CAT-EM) (CAT-EM)

Schizophrenia | Schizoaffective Disorder

United States
McMaster University
Hamilton Health Sciences Corporation; Heart and Stroke Foundation of Ontario; Population Health Research Institute and other collaborators

Completed

Vascular Events In Noncardiac Surgery Patients Cohort Evaluation Study (VISION) (VISION)

Myocardial Infarction | Stroke | Cardiac Arrest | Vascular Death

Brazil, Canada, China, Colombia, India, Malaysia, Spain
Medical Research Council
National Health and Medical Research Council, Australia; AstraZeneca; Cancer... and other collaborators

Unknown

An RCT of Concurrent and Maintenance Cediranib in Women With Platinum-sensitive Relapsed Ovarian Cancer (ICON6)

Ovarian Cancer

United Kingdom
McMaster University
Canadian Institutes of Health Research (CIHR); Hamilton Health Sciences Corporation and other collaborators

Completed

SQUEEZE Trial: A Trial to Determine Whether Septic Shock Reversal is Quicker in Pediatric Patients Randomized to an Early Goal Directed Fluid Sparing Strategy vs. Usual Care (SQUEEZE)

Septic Shock

Canada
NC Heart and Vascular Research, LLC
Novate Medical Limited, a BTG Group Company

Completed

A Random Selection of Patients From the SENTRY Study Who Have a Bioconverted Sentry IVC Filter in Situ With a Minimum Dwell Time of 24 Months From a Single Center Follow up

Recurrent Pulmonary Embolism (Disorder)

United States
McMaster University
Canadian Institutes of Health Research (CIHR); Australian and New Zealand Intensive... and other collaborators

Completed

PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT)

Critical Illness | Deep Venous Thrombosis

United States, Australia, Canada, Saudi Arabia, Brazil, United Kingdom
Wake Forest University Health Sciences
Carolinas Trauma Network Research Group; Charlotte, Houston, Milwaukee Prehospital...

Completed

IN Sub-Dissociative Ketamine vs IN Fentanyl

Bone Fracture

United States
The George Institute
National Health and Medical Research Council, Australia; University of British... and other collaborators

Completed

Normoglycaemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation (NICE - SUGAR STUDY)

Hyperglycemia | Critical Illness

Australia
Canadian Critical Care Trials Group
Canadian Institutes of Health Research (CIHR); McMaster University; University...

Completed

The Oscillation for ARDS Treated Early (OSCILLATE) Trial Pilot Study (OSCILLATE)

Acute Respiratory Distress Syndrome

Canada, Saudi Arabia
Canadian Medical and Surgical Knowledge Translation...
Unity Health Toronto; University of Western Ontario, Canada

Not yet recruiting

Functional Investigation of Endothelial Function and Regenerative Cell Exhaustion (FIERCE)

Diabetes Mellitus, Type 2

Canada
José Casaña Granell
University of Alcalá. Physiotherapy in Women's Health (FPSM) Research Group.

Completed

The Effectiveness of Transvaginal Radiofrequency in Women With Stress Urinary Incontinence

Urinary Incontinence | Pelvic Floor Disorders | Pelvic Floor Muscle Weakness | Urinary Incontinence,Stress

Spain
Singapore General Hospital
Whitehead Institute for Biomedical Research; Blood Services Group, Health Sciences...

Terminated

Clinical Ex Vivo Expansion of Human Umbilical Cord Blood Stem and Progenitor Cells

Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Myeloma | Chronic Leukemia

Singapore
Canadian Cancer Trials Group
Canadian Institutes of Health Research (CIHR); Canadian Cancer Society (CCS); Princess Margaret Hospital, University Health Network

Recruiting

Emotion and Symptom-Focused Engagement Trial for Individuals With Acute Leukemia (EASE)

Acute Leukemia

Canada
UMC Utrecht
ZonMw: The Netherlands Organisation for Health Research and Development; Wits... and other collaborators

Completed

The Intensified Treatment Monitoring Strategy to Prevent Accumulation of Drug Resistance (ITREMA) Trial (ITREMA)

HIV/AIDS

South Africa
NorthShore University HealthSystem
National Cancer Institute (NCI); Wake Forest University Health Sciences; Van... and other collaborators

Completed

Clinical Validity and Utility of Genomic-targeted Chemoprevention of PCa: Aim 4a

Prostate Cancer | Prostate Cancer, Familial | Hereditary Prostate Cancer
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); Ontario Ministry of Health and... and other collaborators

Unknown

Towards RECOVER: Outcomes and Needs Assessment in Intensive Care Unit (ICU) Survivors of Prolonged Mechanical Ventilation and Their Caregivers (RECOVER)

Critically Ill

Canada
Canadian Critical Care Trials Group
Canadian Institutes of Health Research (CIHR); McMaster University; University...

Terminated

The Oscillation for Acute Respiratory Distress Syndrome (ARDS) Treated Early (OSCILLATE) Trial (OSCILLATE)

Acute Respiratory Distress Syndrome (ARDS)

Chile, Canada, United States, India, Saudi Arabia
CHU de Quebec-Universite Laval
Canadian Institutes of Health Research (CIHR); Canadian Critical Care Trials... and other collaborators

Completed

HEMOglobin Transfusion Threshold in Traumatic Brain Injury OptimizatioN: The HEMOTION Trial (HEMOTION)

Traumatic Brain Injury | Transfusion

Canada, United Kingdom, Brazil, France
Stanford University
Brigham and Women's Hospital; Allegheny Singer Research Institute (also known... and other collaborators

Completed

Low Fluoroscopy Afib Ablation Registry

Atrial Fibrillation

United States
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Technische Universität Dresden; Canadian Critical Care Trials Group and other collaborators

Recruiting

Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock (UC-CISSII)

Pathologic Processes | Infections | Sepsis | Systemic Inflammatory Response Syndrome | Inflammation | Shock | Septic Shock

Canada

Clinical Trials Sponsored by LifeMark Health Research Group

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