Search clinical trials for: affinity

Total 141 results

Inari Medical

Active, not recruiting

ClotTriever Outcomes (CLOUT) Registry (CLOUT)

DVT | Deep Vein Thrombosis Leg | Chronic DVT of Lower Extremity | Acute DVT of Lower Extremity

United States
Achieve Life Sciences

Completed

A Second Study of Cytisinicline for Smoking Cessation in Adult Smokers (ORCA-3)

Smoking Cessation

United States
AbbVie
Endo Pharmaceuticals; Allergan Sales, LLC; Acerus Pharmaceuticals Corporation; Upsher-Smith...

Completed

A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men (TRAVERSE)

Cardiovascular Diseases | Hypogonadism

United States, Puerto Rico
Bayer

Terminated

A Study to Learn How Well the Study Treatment Asundexian Works and How Safe it is Compared to Apixaban to Prevent Stroke or Systemic Embolism in People With Irregular and Often Rapid Heartbeat (Atrial Fibrillation), and at Risk for Stroke (OCEANIC-AF)

Atrial Fibrillation | Prevention of Stroke or Systemic Embolism

Canada, United States, Israel, Korea, Republic of, China, Taiwan, Belgium, Australia, Singapore, Malaysia, Slovakia, United Kingdom, Czechia, Latvia, Japan, Brazil, Lithuania, Germany, France, Sweden, Turkey, Switzerland, Estonia, Bul... and more
PureTech
Novotech (Australia) Pty Limited; Clinipace Worldwide

Terminated

LYT-100 in Post-acute COVID-19 Respiratory Disease

Covid19 | Post-acute COVID-19 Respiratory Disease

United States, Brazil, Argentina, Moldova, Republic of, Philippines, Romania, Ukraine, United Kingdom
University of Pennsylvania

Withdrawn

Give a MANNA a Fish, Teach a MANNA to Fish

Liver Diseases | Malnutrition | Cirrhosis, Liver
Organogenesis
Premier Research Group plc

Active, not recruiting

Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

Knee Osteoarthritis

United States
Pacira Pharmaceuticals, Inc
Medpace, Inc.

Terminated

Study to Evaluate the Efficacy and Safety of FX006 in Patients With Glenohumeral Osteoarthritis or Shoulder Adhesive Capsulitis

Adhesive Capsulitis | Osteoarthritis of the Shoulder

United States
Amgen

Completed

A Cross-sectional Study of Lipoprotein(a) Levels in Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD)

Atherosclerotic Cardiovascular Disease

Canada, United States, Belgium, Spain, China, Korea, Republic of, Australia, Netherlands, Austria, Czechia, Taiwan, Hungary, Italy, Portugal, United Kingdom, Greece, Hong Kong, Turkey, France, Bulgaria, Germany, Finland, Japan, Sweden, ... and more
AbbVie

Completed

A Clinical Study to Evaluate the Safety and Efficacy of Elagolix in Participants With Moderate to Severe Endometriosis-Associated Pain

Endometriosis

United States, Canada, Puerto Rico
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Systemic Mastocytosis | Recurrent... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Flotetuzumab for the Treatment of Pediatric Recurrent or Refractory Acute Myeloid Leukemia

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia

United States
Abbott Medical Devices

Completed

TactiFlex Paroxysmal Atrial Fibrillation IDE Trial

Paroxysmal Atrial Fibrillation

United States, Canada, Australia, Austria, Czechia, Germany, Hong Kong, Italy, Netherlands, Taiwan
Astellas Pharma Global Development, Inc.

Completed

A Study to Find Out How Safe Long-term Treatment With Fezolinetant is in Women With Hot Flashes Going Through Menopause (Skylight 4)

Hot Flashes

United States, Czechia, Canada, Latvia, Poland, Spain, Ukraine, United Kingdom
Astellas Pharma Global Development, Inc.

Completed

A Study to Find Out if Fezolinetant Helps Reduce Moderate to Severe Hot Flashes in Women Going Through Menopause - 2 (Skylight 2)

Hot Flashes

United States, Canada, Czechia, United Kingdom, Latvia, Poland, Spain
AbbVie

Completed

A Study to Investigate the Safety and Efficacy of Elsubrutinib and Upadacitinib Given Alone or in Combination in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE) (SLEek)

Systemic Lupus Erythematosus (SLE)

United States, Argentina, Australia, Bulgaria, Canada, China, Colombia, France, Germany, Hungary, Italy, Japan, Korea, Republic of, Mexico, Netherlands, New Zealand, Poland, Puerto Rico, Spain, Taiwan, United Kingdom
Avalo Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of AVTX-002 for the Treatment of Poorly Controlled Non-Eosinophilic Asthma.

Non-Eosinophilic Asthma

United States
ModernaTX, Inc.

Active, not recruiting

Moderna Vaccine mRNA-1345 Observational Respiratory Syncytial Virus (RSV) Study

Respiratory Syncytial Virus

United States
Pulmotect, Inc.
United States Department of Defense

Completed

The Use PUL-042 to Reduce the Infection Rate and Progression to COVID-19 in Adults Exposed to SARS-CoV-2

COVID-19

United States
Nektar Therapeutics
Bristol-Myers Squibb

Terminated

Study to Compare Adjuvant Immunotherapy of Bempegaldesleukin Combined With Nivolumab Versus Nivolumab After Complete Resection of Melanoma in Patients at High Risk for Recurrence (PIVOT-12)

Melanoma | Melanoma (Skin) | Melanoma Stage IV | Melanoma Stage III

United States, Spain, Germany, France, Australia, Italy, Greece, Israel, Russian Federation, New Zealand, Austria, United Kingdom, Netherlands, Portugal, Poland, Czechia, Romania
Oregon Social Learning Center

Enrolling by invitation

Adaptation and Evaluation of the KEEP Model

Post Traumatic Stress Disorder | Depression, Anxiety | Suicide and Self-harm | Externalizing Behavior

United States
Pulmotect, Inc.
United States Department of Defense

Completed

The Use of PUL-042 Inhalation Solution to Reduce the Severity of COVID-19 in Adults Positive for SARS-CoV-2 Infection

COVID-19

United States
Sun Yat-sen University
Guangdong Xiangxue Precision Medical Technology Co., Ltd.

Active, not recruiting

NY-ESO-1-specific T Cell Receptor (TCR) T Cell in Sarcoma

Soft Tissue Sarcoma | Bone Sarcoma

China
GlaxoSmithKline
CureVac

Completed

Safety, Reactogenicity, and Immunogenicity Trial of CV2CoV mRNA Vaccine Against SARS-CoV-2 in Seropositive Adult Participants

SARS-CoV-2

United States
AbbVie

Completed

A Study to Investigate How Well Ravagalimab (ABBV-323) Works and How Safe it is in Participants With Moderate to Severe Ulcerative Colitis Who Failed Prior Therapy

Ulcerative Colitis (UC)

United States, Canada, France, Germany, Hungary, Italy, Korea, Republic of, Netherlands, Spain, United Kingdom
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip (FACT OA2)

Osteoarthritis, Knee | Osteoarthritis, Hip

United States
The Heartburn Foundation

Active, not recruiting

Registry of Outcomes From AntiReflux Surgery (ROARS)

Hiatal Hernia | Gastroesophageal Reflux Disease

United States
Children's Hospital Medical Center, Cincinnati
ExThera Medical Corporation

Enrolling by invitation

Registry of Seraph®-100 Microbind® Affinity Blood Filter for COVID-19 Under EUA

COVID-19 | SARS-CoV 2

United States
Sorrento Therapeutics, Inc.

Active, not recruiting

Study to Evaluate Intra-articular Resiniferatoxin to Treat Moderate to Severe Pain From Knee Osteoarthritis

Knee Osteoarthritis | Osteoarthritis, Knee | Knee Pain Chronic

United States
AbbVie

Completed

A Study of the Effect of Topical Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism

Hypogonadism

United States
Henry M. Jackson Foundation for the Advancement...
Uniformed Services University of the Health Sciences

Active, not recruiting

Blood Purification With Seraph 100 Microbind Affinity Blood Filter for Treatment of Severe COVID19 Observational Study (PURIFY-OBS-1)

Covid19

United States
Entia Ltd

Enrolling by invitation

Blood Testing at Entia

Healthy

United Kingdom
Inovio Pharmaceuticals

Completed

REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)

Cervical Dysplasia | Cervical High Grade Squamous Intraepithelial Lesion | HSIL

United States, Spain, Lithuania, Estonia, South Africa, Argentina, Brazil, Finland, Poland, Puerto Rico
ACADIA Pharmaceuticals Inc.

Terminated

Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee

Osteoarthritis Pain

United States
Entia Ltd

Completed

Project Affinity: Excess Cancer Blood Testing

Cancer

United Kingdom
Kiniksa Pharmaceuticals, Ltd.

Completed

Study of Mavrilimumab (KPL-301) in Participants Hospitalized With Severe Corona Virus Disease 2019 (COVID-19) Pneumonia and Hyper-inflammation

COVID

United States, Brazil, South Africa, Chile, Peru
Florida State University
Military Suicide Research Consortium

Completed

A Conditioning Paradigm to Increase Affinity for Sacredness of Life

Suicidal Ideation | Suicide, Attempted | Suicide and Self-harm | Non-suicidal Self-injury

United States
Taiwan Liposome Company

Completed

Extended and Controlled Release Liposomal Formulated Dexamethasone for Chronic Knee OA Pain (EXCELLENCE)

Osteoarthritis of the Knee

United States, Australia
Centrexion Therapeutics

Completed

A Clinical Study to Test Efficacy and Safety of Repeat Doses of CNTX-4975-05 in Patients With Osteoarthritis Knee Pain

Osteoarthritis, Knee

United States
Biogen

Terminated

Efficacy and Safety of BIIB033 (Opicinumab) as an Add-on Therapy to Disease-Modifying Therapies (DMTs) in Relapsing Multiple Sclerosis (MS) (AFFINITY)

Multiple Sclerosis

United States, Italy, Spain, Belgium, Germany, Switzerland, Australia, Hungary, France, Poland, United Kingdom, Czechia, Israel, Canada, Netherlands
Medicago

Active, not recruiting

Study of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine in Adults

SARS-CoV-2 Infection

United States, Canada, United Kingdom, Argentina, Brazil, Mexico
Boston Scientific Corporation

Completed

Strategic Management to Optimize Response To Cardiac Resynchronization Therapy (SMART CRT)

Heart Failure

United States, United Kingdom, France, Germany, Netherlands, Spain, Ireland, Canada, Japan, Switzerland, Italy
AbbVie

Completed

A Study to Evaluate the Safety and Efficacy of Elagolix for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

Uterine Fibroids

United States, Puerto Rico
Entia Ltd
The Christie NHS Foundation Trust

Completed

Affinity: Hospital Trial

Cancer

United Kingdom
Centrexion Therapeutics

Completed

An Open-label, 8-week Safety, Efficacy, and Assessment of Cooling Methods for Administration of CNTX-4975-05 for Knee OA

Knee Osteoarthritis

United States
Cadent Therapeutics

Completed

Study of CAD-9303 in Subjects With Schizophrenia (Affinity-1)

Schizophrenia

United States
Algernon Pharmaceuticals
Novotech (Australia)

Completed

Safety and Efficacy of NP-120 (Ifenprodil) for the Treatment of Hospitalized Patient With Confirmed COVID-19 Disease

COVID

Philippines, Australia, United States, Romania
AbbVie

Terminated

A Study of Women Receiving Standard of Care (SOC) for the Treatment of Pelvic Pain Due to Suspected or Confirmed Endometriosis and the Impact on the Disease or Symptom Progression.

Endometriosis | Dysmenorrhea | Chronic Pelvic Pain

United States
Medical University Innsbruck

Completed

Quantification of Clinically Relevant Drug Induced Changes in HbO2 Affinity

Oxygen Deficiency

Austria
Dynavax Technologies Corporation
Merck Sharp & Dohme LLC

Terminated

A Trial of Intratumoral Injections of SD-101 in Combination With Pembrolizumab in Patients With Metastatic Melanoma or Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Metastatic Melanoma | Head Neck Cancer

United States, Germany, New Zealand, Australia

Search clinical trials for: affinity

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ghana

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations