Clinical Trials Sponsored by Ashford and St. Peter's Hospitals NHS Trust

Total 161 results

Imperial College London
University College London Hospitals; Guy's and St Thomas' NHS Foundation Trust

Completed

Neuroprotective Effects of Hypothermia Combined With Inhaled Xenon Following Perinatal Asphyxia (TOBYXe)

Hypoxic Ischaemic Encephalopathy

United Kingdom
University College, London
London School of Hygiene and Tropical Medicine; King's College London; Odense... and other collaborators

Completed

Effect of Remote Ischaemic Conditioning on Clinical Outcomes in STEMI Patients Undergoing PPCI (CONDI2/ERIC-PPCI)

Myocardial Reperfusion Injury | STEMI

Denmark, United Kingdom, Spain, Serbia
Intensive Care National Audit & Research Centre
University of Oxford; Guy's and St Thomas' NHS Foundation Trust; University of... and other collaborators

Unknown

Renal Replacement Anticoagulant Management (RRAM)

Critical Illness

United Kingdom
University of Southampton
University of Nottingham; Nottingham University Hospitals NHS Trust; East Kent... and other collaborators

Recruiting

Aspirin to Target Arterial Events in Chronic Kidney Disease (ATTACK)

Cardiovascular Diseases | Chronic Kidney Diseases | Bleeding

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Monash University; Australian and New Zealand Intensive Care Research Centre; Royal Surrey County Hospital NHS Foundation Trust

Recruiting

Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome (ACES)

COVID | Acute Respiratory Distress Syndrome

United Kingdom
Perspectum
King's College Hospital NHS Trust; University of Coimbra; Liverpool University... and other collaborators

Completed

Non-invasive Rapid Assessment of NAFLD Using Magnetic Resonance Imaging With LiverMultiScan (RADIcAL1)

Metabolic Syndrome | NAFLD | NASH - Nonalcoholic Steatohepatitis

United Kingdom, Germany, Netherlands, Portugal
King's College London
King's College Hospital NHS Trust; Guy's and St Thomas' NHS Foundation Trust; National Institute for Health Research, United Kingdom

Suspended

A Psychoeducational Intervention Supporting Patients With an Inherited Cardiac Condition (PISICC)

Cardiomyopathies | Inherited Cardiac Conduction Disorder

United Kingdom
PENTA Foundation
King's College Hospital NHS Trust; Karolinska Institutet; Hospital General Universitario... and other collaborators

Recruiting

European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC) SARS-CoV-2 Antibody Study Protocol. Covid-19 (SARS-Cov2)

Sars-Cov2 Antibodies in Children and Adolescents Living With HIV

Spain, United Kingdom, South Africa, Belgium, Greece, Ukraine
University of Birmingham
King's College Hospital NHS Trust; University College London Hospitals; University... and other collaborators

Completed

Mifepristone and Misoprostol Versus Misoprostol Alone in the Medical Management of Missed Miscarriage (MifeMiso)

Missed Miscarriage

United Kingdom
Royal Marsden NHS Foundation Trust
King's College Hospital NHS Trust; University College London Hospitals; Imperial... and other collaborators

Recruiting

Nodule IMmunophenotyping Biomarker for Lung Cancer Early Diagnosis Study

Lung Cancer

United Kingdom
University of Aberdeen
Imperial College London; Medical Research Council; Brighton and Sussex University... and other collaborators

Completed

Nitrites in Acute Myocardial Infarction (NIAMI)

Acute ST Elevation Myocardial Infarction

United Kingdom
University of Cambridge
Guy's and St Thomas' NHS Foundation Trust; Manchester University NHS Foundation... and other collaborators

Completed

Observational Cohort Study of a National Extracorporeal Membrane Oxygenation Service for Adults With Respiratory Failure: the NHS ECMO Study. (NHS ECMO)

Acute Respiratory Failure
University of East Anglia
Cambridge University Hospitals NHS Foundation Trust; Cambridgeshire and Peterborough... and other collaborators

Unknown

The Effect of Mindfulness on Cognition and Emotion Following Acquired Brain Injury

Injuries, Brain

United Kingdom
Barts & The London NHS Trust
Royal Marsden NHS Foundation Trust; Guy's and St Thomas' NHS Foundation Trust; Case Western Reserve University and other collaborators

Completed

Diagnostic Accuracy of MRI, DWI MRI, FDG-PET/CT and FEC PET/CT in the Detection of Lymph Node Metastases in Surgically Staged Endometrial and Cervical Carcinoma (MAPPING)

Endometrial Cancer | Surgically Staged Endometrial and Cervical Carcinoma | Cervical Cancer: Invasive Disease, FIGO Stage 1B1 or Higher | Stage 1A With Myometrial Invasion or Any Higher Stage and Grade 3 | Stage 1A With Myometrial Invasion or Any Other Higher Stage and Serous Papillary or... and other conditions

United Kingdom
pSiMedica Limited
Singapore General Hospital; Guy's and St Thomas' NHS Foundation Trust; pSiOncology...

Unknown

32P BioSiliconTM in Addition to Gemcitabine in Pancreatic Cancer

Pancreatic Cancer

Singapore, United Kingdom
Grace Ward
Guy's and St Thomas' NHS Foundation Trust; Royal Berkshire Hospital

Unknown

The Ecological Role of Yeasts in the Human Gut (YIG)

Irritable Bowel Syndrome | Inflammatory Bowel Diseases | Gastrointestinal Disease

United Kingdom
University of Oxford
Cancer Research UK; Guy's and St Thomas' NHS Foundation Trust; NHS Lothian; National... and other collaborators

Completed

Atovaquone With Radical ChemorADIotherapy in Locally Advanced NSCLC (ARCADIAN)

Locally Advanced Non-Small Cell Lung Cancer

United Kingdom
Kronikgune
Odense University Hospital; Assuta Ashdod Hospital; Maccabi Healthcare Services... and other collaborators

Recruiting

Assessment of the Effectiveness, Socio-economic Impact and Implementation of a Digital Solution for Severe Patients (ADLIFE)

Heart Failure NYHA Class III | Heart Failure NYHA Class IV | Chronic Obstructive Pulmonary Disease Severe

Denmark, Germany, Israel, Spain, Sweden, United Kingdom
St George's, University of London
University of Oxford; University Hospitals Bristol and Weston NHS Foundation...

Completed

Immunising Mums Against Pertussis 3 (iMAP3)

Whooping Cough | Immunization; Infection | Maternal Vaccine Exposure

United Kingdom
London School of Hygiene and Tropical Medicine
Barts & The London NHS Trust; St George's University Hospitals NHS Foundation... and other collaborators

Completed

The Trauma INtramuscular Tranexamic Acid Clinical Trial (TraumaINTACT)

Traumatic Haemorrhage

United Kingdom
King's College Hospital NHS Trust
King's College London; Guy's and St Thomas' NHS Foundation Trust; National Institute... and other collaborators

Completed

Neurally Adjusted Ventilatory Assist in Adults at Risk of Delayed Weaning From Mechanical Ventilation (RESTUS)

Adults With Cardiopulmonary Disease at Risk of Prolonged Weaning From Mechanical Ventilation

United Kingdom
Melanoma and Skin Cancer Trials Limited
Norfolk and Norwich University Hospitals NHS Foundation Trust; Peter MacCallum...

Active, not recruiting

MelmarT Melanoma Margins Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma (MelMarT)

Cutaneous Melanoma by AJCC V7 Stage

United Kingdom, United States, Sweden, Australia, Canada
University of Oxford
University College London Hospitals; CSL Behring; Guy's and St Thomas' NHS Foundation... and other collaborators

Completed

Investigating the Role of Early Intravenous Immunoglobulin Treatment for Children With Encephalitis (IgNiTE)

Encephalitis

United Kingdom
King's College London
Imperial College London; Medical Research Council; Guy's and St Thomas' NHS Foundation... and other collaborators

Unknown

Treg Immunotherapy in Crohn's Disease (TRIBUTE)

Crohn Disease
King's College London
Hospital Universitari Vall d'Hebron Research Institute; Örebro University,... and other collaborators

Recruiting

ADHD Remote Technology Study of Cardiometabolic Risk Factors and Medication Adherence (ART-CARMA)

Cardiovascular Diseases | Medication Adherence | Attention Deficit Hyperactivity Disorder

United Kingdom, Spain
University Hospital Southampton NHS Foundation...
Royal Marsden NHS Foundation Trust; University College London Hospitals; Cambridge... and other collaborators

Unknown

Coronavirus Infection in Primary or Secondary Immunosuppressed Children and Adults. (ImmunoCOVID)

COVID | Infection | Immune Deficiency | Immune Suppression | Children, Adult

United Kingdom
Kingston University
National Institute for Health Research, United Kingdom; St George's University... and other collaborators

Recruiting

Non-medical Practitioner Workforce in the Urgent and Emergency Care System Skill-mix in England (SKILLmix-ED)

Emergencies

United Kingdom
University of Plymouth
Carl Zeiss Meditec AG; University Hospital Plymouth NHS Trust; Glasgow Caledonian... and other collaborators

Recruiting

Vision and Balance Changes After Bilateral Implantation of Toric IOLs

Cataract Bilateral | Astigmatism Bilateral

United Kingdom
Helsinki University Central Hospital
Guy's and St Thomas' NHS Foundation Trust; University Hospital, Ghent; Medical... and other collaborators

Completed

REVERSE-AKI Randomized Controlled Pilot Trial (REVERSE-AKI)

Critical Illness | Acute Kidney Injury

Finland, Belgium, Switzerland, Australia, United Kingdom
St. Anna Kinderkrebsforschung
Centre Leon Berard; Medical University of Graz; Fondazione IRCCS Istituto Nazionale... and other collaborators

Unknown

Long Term Continuous Infusion ch14.18/CHO Plus s.c. Aldesleukin (IL-2) (LTI)

Neuroblastoma

France, Spain, Austria, Germany, Israel, Italy, United Kingdom
King's College London
King's College Hospital NHS Trust; The Hospital for Sick Children; Cardiff University and other collaborators

Completed

Rolandic Epilepsy Genomewide Association International Study (REGAIN)

Rolandic Epilepsy

United States, United Kingdom, Argentina, Canada, Greece, Italy, Spain
Guy's and St Thomas' NHS Foundation Trust
University of Nottingham; Imperial College London; University College, London; Cambridge... and other collaborators

Not yet recruiting

BEARS Training Package to Maximise Hearing Abilities in Older Children and Teenagers With Bilateral Cochlear Implants (BEARS)

Hearing Loss | Deafness | Hearing Loss, Sensorineural | Hearing Impaired Children and Adolescents
University College, London
London School of Hygiene and Tropical Medicine; King's College London; University... and other collaborators

Recruiting

Deep Brain Stimulation in Tourette Syndrome (Op-TICS)

Tourette Syndrome | Deep Brain Stimulation

United Kingdom
Children's Hospital Medical Center, Cincinnati
University of Colorado, Denver; Children's Hospital of Philadelphia; Duke University and other collaborators

Recruiting

Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation (HELPFUL)

Sickle Cell Disease | Sickle Cell Anemia

United States
Imperial College London
London School of Hygiene and Tropical Medicine; The Leeds Teaching Hospitals... and other collaborators

Completed

Immediate Management of the Patient With Rupture : Open Versus Endovascular Repair (IMPROVE)

Abdominal Aortic Aneurysm

United Kingdom, Canada
Norwegian University of Science and Technology
Oslo University Hospital; Guy's and St Thomas' NHS Foundation Trust; Cedars-Sinai... and other collaborators

Completed

Multimodal Intervention for Cachexia in Advanced Cancer Patients Undergoing Chemotherapy (MENAC)

Neoplasms | Cachexia

Norway, United Kingdom, Germany, United States, Canada, Switzerland
King's College London
Boston Children's Hospital; Massachusetts Institute of Technology; Guy's and... and other collaborators

Recruiting

Prediction of Adverse Outcome Using Fetal MRI in Pregnancies at Risk of Preterm Birth

Preterm Birth Complication

United Kingdom
Advanced Cooling Therapy, Inc., d/b/a Attune Medical
University of Colorado, Denver; University of Pennsylvania; Beth Israel Deaconess... and other collaborators

Recruiting

Oesophageal Protection Study: A Multicentre Study. (IMPACT II)

Complication | AF - Atrial Fibrillation | Atrio-Esophageal Fistula

United States, United Kingdom
The University of Western Australia
Johns Hopkins University; Vanderbilt University Medical Center; Guy's and St... and other collaborators

Recruiting

AMPLE-3: IPC Plus Talc vs VATS in Management of Malignant Pleural Effusion (AMPLE-3)

Cancer | Respiratory Disease | Malignant Pleural Effusion

Australia
Medical University of Graz
Medical University of Vienna; Goethe University; Guy's and St Thomas' NHS Foundation... and other collaborators

Recruiting

The VITDALIZE Study: Effect of High-dose Vitamin D3 on 28-day Mortality in Adult Critically Ill Patients (VITDALIZE)

Critical Illness | Covid19 | Vitamin D Deficiency

Austria, Belgium
Chinese University of Hong Kong
National Taiwan University Hospital; Changi General Hospital; Oxford University... and other collaborators

Recruiting

Diagnostic Accuracy of a Panel of Bacterial Gene Markers (M3) for Colorectal Advanced Neoplasia (M3-PRO)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenoma

Hong Kong
Guy's and St Thomas' NHS Foundation Trust
London School of Hygiene and Tropical Medicine; King's College London; St Thomas... and other collaborators

Recruiting

Controlled Trial of High-risk Coronary Intervention With Percutaneous Left Ventricular Unloading (CHIP-BCIS3)

Coronary Artery Disease | Ischemic Heart Disease

United Kingdom
Tenaya Therapeutics
Medical University of South Carolina; Johns Hopkins University; University of... and other collaborators

Recruiting

Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (RIDGE)

Arrhythmogenic Right Ventricular Cardiomyopathy

United States, Italy, United Kingdom, France, Sweden, Germany
Guy's and St Thomas' NHS Foundation Trust
King's College London; University of Oxford; University of Liverpool; National... and other collaborators

Unknown

Sham-Controlled RCT on 10kHz High-Frequency Spinal Cord Stimulation for Chronic Neuropathic Low Back Pain (Modulate-LBP) (Modulate-LBP)

Chronic Low Back Pain | Neuropathic Pain | Refractory Pain

United Kingdom
Hospital Clinic of Barcelona
University Hospital, Antwerp; Academisch Medisch Centrum - Universiteit van... and other collaborators

Unknown

COVIDAR - Arrhythmias in COVID-19 (COVIDAR)

Atrial Fibrillation | Arrhythmia | COVID | Atrioventricular Block | Ventricular Arrythmia | Qt Interval, Variation in | Bradyarrhythmia | Torsades de Pointe Caused by Drug

Spain, Belgium, Italy, Netherlands, United Kingdom
PENTA Foundation
Baylor College of Medicine; University Hospital Birmingham NHS Foundation Trust and other collaborators

Recruiting

DTG/3TC Fixed Dose Formulations for the Maintenance of Virological Suppression in Children With HIV Infection Aged 2 to <15 Years Old (D3 (Penta21))

HIV Infections

Spain, United Kingdom, Thailand, South Africa, Uganda
Mercator MedSystems, Inc.
University of South Florida; Northwestern University; Stony Brook University; Guy... and other collaborators

Recruiting

Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT (DEXTERITY-AFP)

Thrombosis, Deep Vein | Iliofemoral; Thrombosis

United States, Ireland, United Kingdom
Mercator MedSystems, Inc.
University of South Florida; Northwestern University; Stony Brook University; Guy... and other collaborators

Recruiting

Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Subacute and Chronic Iliofemoral DVT (DEXTERITY-SCI)

Iliofemoral; Thrombosis

United States, Ireland, United Kingdom
Medical University of Vienna
M.D. Anderson Cancer Center; Odense University Hospital; Radboud University Medical... and other collaborators

Recruiting

Image Guided IMRT, Radiochemotherapy and MRI-based IGABT in Locally Advanced Cervical Cancer (EMBRACEII)

Uterine Cervical Neoplasms

Austria
Academisch Medisch Centrum - Universiteit van Amsterdam...
University Medical Center Groningen; Erasmus Medical Center; Guy's and St Thomas... and other collaborators

Completed

N-Acetylcysteine in Patients With Sickle Cell Disease (NAC)

Sickle Cell Disease

Belgium, Netherlands, United Kingdom

Clinical Trials Sponsored by Ashford and St. Peter's Hospitals NHS Trust

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