Search clinical trials for: Hemophilia B, gene therapy

Total 293694 results

National Institute of Allergy and Infectious Diseases...

Completed

A Study of the Safety and Effectiveness of Hydroxyurea in Patients on Potent Antiretroviral Therapy and Who Have Less Than 200 Copies/ml of HIV RNA in Their Blood

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Comparative Study of Combination Antiretroviral Therapy in Children and Adolescents With Advanced HIV Disease

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Treatment Success and Failure in HIV-Infected Subjects Receiving Indinavir in Combination With Nucleoside Analogs: A Rollover Study for ACTG 320

HIV Infections

United States, Puerto Rico
Shire

Approved for marketing

Treatment Protocol of Velaglucerase Alfa for Patients With Type 1 Gaucher Disease

Gaucher Disease, Type 1

United States
Baxalta now part of Shire

Completed

Non-Interventional Study to Capture the Patient Experience on Gene Therapy for Hemophilia Within the AskBio009-101 Study Through Patient and Investigator Interviews

Hemophilia B

United States
Novartis Pharmaceuticals

Completed

Efficacy and Long-Term Safety of Vildagliptin as Add-on Therapy to Metformin in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Korea, Republic of, Latvia, Peru, Lithuania, Israel, Norway, Finland, Argentina, Austria, Belgium, Germany, Greece, Guatemala, Hungary, India, Italy, Mexico, Poland, Romania, Slovakia, Venezuela
Novartis Pharmaceuticals

Terminated

Safety and Efficacy of QAX576 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United States, United Kingdom
Icahn School of Medicine at Mount Sinai
Allergan

Completed

Botulinum Toxin is a Potential Prophylactic Therapy for Minimizing Post-excisional Scarring (Allergan Botox Scar Study)

Post-operative Excessive Scarring

United States
ZOLL Circulation, Inc., USA

Completed

COOL AMI EU Pilot Trial to Assess Cooling as an Adjunctive Therapy to Percutaneous Intervention in Patients With Acute Myocardial Infarction

Acute Myocardial Infarction

Slovenia, Poland, Austria, Estonia, Hungary, Serbia, Sweden, United Kingdom
Bayer

Completed

Extension at 10 Years of the: "Observational Study Evaluating Efficacy and Costs of Secondary Prophylaxis vs On-demand Therapy With Kogenate Bayer in Patients With Severe Haemophilia A." (POTTER 10)

Hemophilia A

Italy
Oxford BioMedica
Sanofi

Completed

TroVax Renal Immunotherapy Survival Trial

Clear Cell Renal Carcinoma

United States, Spain, Israel, United Kingdom, France, Russian Federation, Germany, Poland, Romania, Ukraine
University of Zurich

Completed

Feasibility of a Blended Therapy Approach (bletheRD)

Feasibility | Exercise | Telemedicine | Myositis | Haemophilia

Switzerland
Pfizer

Completed

A Gene Therapy Study for Hemophilia B

Hemophilia B

United States, Australia
Necmettin Erbakan University

Completed

Effectiveness of Manual Therapy and Strengthening Exercises in Hemophilic Arthropathy of the Elbow Joint

Hemophilia | Arthritis

Turkey
Necmettin Erbakan University

Completed

The Effects of Manual Therapy in Hemophilic Patients

Hemophilia | Arthropathy Hemophilic

Turkey
Catholic University of the Sacred Heart

Unknown

PHYSICAL ACTIVITY AND FVIII CLEARANCE: RELEVANCE FOR PERSONALIZED THERAPY IN SEVERE HAEMOPHILIA A (PHYSEMO) (PHYSEMO)

Hemophilia A

Italy
Sinocelltech Ltd.
Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Parexel; Q2...

Completed

Evaluation of SCT800 in Prophylaxis Therapy on Previous Treated Patients With Severe Hemophilia A

Hemophilia A

China
Bausch Health Americas, Inc.
Cosmo Technologies Ltd

Completed

(CB-01-02/02) Randomized Placebo Controlled Trial of Budesonide-multi-matrix System (MMX™) 6 mg and 9 mg in Patients With Ulcerative Colitis

Ulcerative Colitis

Russian Federation, United Kingdom, Latvia, Poland, Estonia, Belgium, Australia, Lithuania, France, Sweden, Israel, Italy, Romania, Slovakia, Ukraine
Riphah International University

Completed

Cyriax Manipulation in Lumbar Derangement Syndrome

Derangement; Low Back

Pakistan
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma

Brain Tumor | Central Nervous System Tumor

United States, Canada, Australia, Switzerland, Netherlands, New Zealand
Hospices Civils de Lyon

Unknown

TGA (Thrombin Generation Assay) and Prophylaxis in Haemophilia (HOPE)

Haemophilia A

France
Shenzhen Geno-Immune Medical Institute

Unknown

Lentiviral FIX Gene Therapy

Hemophilia B
Shenzhen Geno-Immune Medical Institute

Unknown

Lentiviral FVIII Gene Therapy

Hemophilia A

China
Ahlia University
Cairo University

Completed

Effect of Interferential l Therapy on Low Back Pain ([PTREC])

Low Back Pain

Egypt
Pfizer

Terminated

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects (SPIRE-2)

Cardiovascular Disease

United States, Finland, Netherlands, Spain, Belgium, Germany, Czechia, Switzerland, Denmark, Australia, United Kingdom, Korea, Republic of, Hungary, Israel, Poland, Taiwan, Mexico, Turkey, Ireland, Canada, New Zealand, South Africa, Brazi... and more
University of Minho
Hospital Sao Joao

Completed

Effectiveness of Psychological Interventions in Haemophilia (PSY_HaEMOPEQ)

Haemophilia

Portugal
Spark Therapeutics
Children's Hospital of Philadelphia; University of Pittsburgh; St. James's Hospital... and other collaborators

Terminated

Hemophilia B Gene Therapy With AAV8 Vector

Hemophilia B

United States, Australia
Real Fundación Victoria Eugenia

Completed

Fascial Therapy in Elbow Hemophilic Arthropathy (HeL-Fascial)

Hemophilia

Spain
Abbott Medical Devices

Completed

More Options Available With a Quadripolar LV Lead pRovidE In-clinic Solutions to CRT Challenges (MORE-CRT)

Heart Failure | Perioperative/Postoperative Complications | Postoperative Cardiac Complication | Left Ventricular Cardiac Dysfunction | Inappropriate Phrenic Nerve Stimulation

Spain, United Kingdom, Netherlands, France, Israel, Finland, Canada, Belgium, Germany, Italy, India, Poland, Switzerland
Children's Hospital of Eastern Ontario
Jesse's Journey-The Foundation for Gene and Cell Therapy

Completed

Stacking Exercises Aid the Decline in FVC and Sick Time (STEADFAST)

Duchenne Muscular Dystrophy

Canada
Ultragenyx Pharmaceutical Inc

Terminated

Safety and Dose Finding Study of DTX101 (AAVrh10FIX) in Adults With Moderate/Severe to Severe Hemophilia B

Hemophilia B

United States, United Kingdom, Bulgaria
Brazilian Institute of Higher Education of Censa

Completed

Ventilator Hyperinflation With Increase of Inspiratory Time

Mechanical Ventilation | Lung Infection

Brazil
Boehringer Ingelheim

Completed

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Atrial Fibrillation | Percutaneous Coronary Intervention

Canada, United States, Spain, Korea, Republic of, Australia, Germany, Taiwan, Hong Kong, Thailand, United Kingdom, Turkey, Netherlands, Ireland, Hungary, Croatia, Colombia, Israel, Singapore, Italy, New Zealand, Greece, Mexico, Norway, Swed... and more
Henan University of Traditional Chinese Medicine
Peking University First Hospital; Chengdu University of Traditional Chinese... and other collaborators

Unknown

Study on Children Henoch-Schönlein Purpura Nephritis With TCM Multistep Treatment

Henoch-Schönlein Purpura Nephritis

China
Pfizer

Terminated

The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects (SPIRE-1)

Cardiovascular Disease

Finland, United States, Netherlands, Spain, Korea, Republic of, China, Israel, Belgium, Germany, Australia, Czechia, Taiwan, Denmark, United Kingdom, Hungary, Poland, France, Mexico, Turkey, Canada, New Zealand, Colombia, Switzerland, Irelan... and more
GlaxoSmithKline

Completed

A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Asthma Uncontrolled on Non-steroidal Therapy.

Asthma

United States, Germany, Poland, Russian Federation, Bulgaria, Estonia, Canada, France, Korea, Republic of, Peru, Philippines, Mexico, Sweden, Slovakia
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Essentiality of INH in TB Therapy

Tuberculosis

South Africa
Alexion Pharmaceuticals

Completed

Extension Study of Eculizumab in Patients With Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Hemoglobinuria, Nocturnal

United States, Australia, Belgium, Canada, Germany, Italy, Spain, Sweden, United Kingdom, France, Ireland, Netherlands
Universidad Católica San Antonio de Murcia

Completed

Physiotherapy in the Haemophilic Arthropathy of the Elbow. (ELBOW)

Patients With Hemophilia

Spain
Hampshire Hospitals NHS Foundation Trust
Uppsala University; University of Wales Cardiff United Kingdom (UK)

Completed

Efficacy and Cost Effectiveness of Pharmacokinetic Dosing in Haemophilia A

Severe Haemophilia A

United Kingdom
Children's Hospital Los Angeles

Withdrawn

Individualizing Hemophilia Bypassing Agent Therapy Utilizing Thromboelastography

Hemophilia A With Inhibitors
Pfizer

Completed

A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's Disease

Crohn's Disease

Korea, Republic of, United States, Spain, Netherlands, Australia, Israel, Canada, Czechia, Japan, Germany, Hungary, Austria, Bulgaria, Greece, South Africa, Ukraine, France
Real Fundación Victoria Eugenia

Completed

Effectiveness of the Myofascial Therapy in the Hemophilic Arthropathy of Ankle

Haemophilia
Jorge Paredes Vieyra

Completed

Incidence of Post-operative Pain After Single-visit Versus Two-visit Treatment

Post-operative Pain
Genzyme, a Sanofi Company

Completed

A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease (ENGAGE)

Gaucher Disease, Type 1

United States, United Kingdom, Bulgaria, Canada, Colombia, India, Israel, Lebanon, Mexico, Russian Federation, Serbia, Tunisia
Pfizer

Completed

The Safety And Efficacy Of Maintenance Therapy With CP-690,550

Crohn's Disease

United States, Spain, Israel, Netherlands, Australia, Canada, Japan, Germany, Korea, Republic of, Hungary, Austria, Bulgaria, Czech Republic, Greece, South Africa, Ukraine, France
GlaxoSmithKline

Completed

A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Asthma Uncontrolled on Low-Dose ICS Therapy.

Asthma

United States, Germany, Estonia, Canada, Korea, Republic of, South Africa, Mexico, Greece, Russian Federation, Philippines, Slovakia, Poland, Romania
Bayer

Completed

A Trial to Compare Prophylaxis Therapy to On-demand Therapy With a New Full Length Recombinant FVIII in Patients With Severe Hemophilia A (Leopold II)

Hemophilia A

China, United States, Ukraine, Taiwan, Mexico, Thailand, Romania, Colombia, Turkey, Serbia, Russian Federation, South Africa, Japan, Indonesia, Argentina, Czech Republic, India, Slovakia
Genzyme, a Sanofi Company

Completed

A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease Who Have Reached Therapeutic Goals With Enzyme Replacement Therapy (ENCORE) (ENCORE)

Gaucher Disease, Type 1

United States, France, Germany, Italy, Brazil, Australia, Argentina, Canada, Egypt, Russian Federation, Spain, United Kingdom
Novartis Pharmaceuticals

Completed

A Randomized, Phase 2, Neoadjuvant Study of Weekly Paclitaxel With or Without LCL161 in Patients With Triple Negative Breast Cancer

Breast Cancer

Spain, United Kingdom, Taiwan, Australia, Russian Federation, Germany, Korea, Republic of, Ireland, United States, Italy, Brazil, Czech Republic

Search clinical trials for: Hemophilia B, gene therapy

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