Search clinical trials for: Randomized Multicenter Trial

Total 46183 results

Universidad de Extremadura
University of Oviedo; Universidad Rey Juan Carlos; University of Évora; AINISE... and other collaborators

Completed

Multicenter, Randomized Trial to Determine the Effect of Therapeutic Riding, on a Group of People With Arthritis (ARTHER)

Arthritis

Spain
Huazhong University of Science and Technology
Shandong University; Zhejiang University

Completed

A Multicenter, Prospective, Randomized Trial of Adjuvant Chemotherapy for Early-Stage Cervical Cancer Patients (CC-01)

Cervical Cancer | Uterine Cervical Neoplasms | Uterine Cervical Cancer

China
University of Pecs

Suspended

Extracorporal Cytokin Removal in Septic Shock: a Prospective, Randomized, Multicenter Clinical Trial (DECRISS)

Septic Shock

Hungary
RedHill Biopharma Limited

Completed

A Study of ABC294640 (Yeliva ®) Alone and in Combination With Hydroxychloroquine Sulfate in Treatment of Patients With Advanced Cholangiocarcinoma

Cholangiocarcinoma | Cholangiocarcinoma Non-resectable | Cholangiocarcinoma, Perihilar | Cholangiocarcinoma, Extrahepatic | Cholangiocarcinoma, Intrahepatic

United States
Ottawa Hospital Research Institute

Active, not recruiting

A Randomized, Multicenter Pragmatic Trial Comparing Bone Pain From a Single Dose of Pegfilgrastim to 5 Doses of Daily Filgrastim in Breast Cancer Patients Receiving Neoadjuvant/Adjuvant Chemotherapy

Early-stage Breast Cancer

Canada
Prestige Biopharma Limited

Completed

A Phase III Trial to Compare the Efficacy, Safety and Pharmacokinetics of HD201 to Herceptin® in HER2+ Early Breast Cancer Patients (TROIKA)

HER2 Positive Breast Cancer

Spain, Malaysia, Estonia, Hungary, Thailand, Belarus, Bulgaria, France, Georgia, Italy, Poland, Russian Federation, Ukraine
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI); Kaiser Permanente; University... and other collaborators

Completed

The Multicenter Randomized HYpertension and VALUEs (HYVALUE) Trial (HYVALUE)

Hypertension

United States
Virginia Commonwealth University

Terminated

Efficient Anterior Shoulder Ultrasound Reduction Multicenter Prospective Randomized Trial (EASiUR)

Shoulder Dislocation

United States
RWTH Aachen University
Clinical Evaluation Research Unit at Kingston General Hospital

Withdrawn

The Effect of Higher Protein Dosing in Critically Ill Patients: A Multicenter Randomized Trial (EFFORTcombo)

Critical Illness | Malnutrition | Frailty | Sarcopenia | Nutritional Disorder

Germany
Beijing Tiantan Hospital
Tasly Pharmaceutical Group Co., Ltd

Active, not recruiting

CerebrAlcare Pills on CereBral Small VesseL DiseasE（CABLE）

Cerebral Small Vessel Diseases

China
Assistance Publique - Hôpitaux de Paris

Completed

Multicenter, Prospective, Randomized, Controlled, Double-blind Trial on the Impact of Rosuvastatin on Subclinical Markers of Atherosclerosis in Patients With Primary Necrotizing Vasculitides (STATVAS)

ANCA-associated Primary Necrotizing Vasculitides

France
3M

Completed

Randomized, Controlled Multicenter Trial of Vacuum Assisted Closure Therapy™ in Diabetic Foot Ulcers

Diabetic Foot Ulcers

United States, Canada
Teijin Pharma Limited

Completed

A Randomized Placebo-controlled Multicenter Trial to Evaluate the Efficacy and Safety of JTR-161, Allogeneic Human Dental Pulp Stem Cell, in Patients With Acute Ischemic stRoke (J-REPAIR) (J-REPAIR)

Acute Ischemic Stroke

Japan
Terumo Europe N.V.
Cromsource

Completed

DIStal Versus COnventional RADIAL Access for Coronary Angiography and Intervention

Coronary Disease

Italy, Belgium, United Kingdom, Hungary, Japan, Czechia, Germany, Netherlands, North Macedonia, Switzerland
Hospices Civils de Lyon

Completed

Surgical Treatment of Spinal Deformity With Sagittal Imbalance Using Patient-specific Rods: A Multicenter, Controlled, Double- Blind Randomized Trial: The PROFILE Study (PROFILE)

Spinal Deformity With Sagittal Imbalance
Poitiers University Hospital

Withdrawn

Amoxicillin-clavulanate Alone or in Combination With Ciprofloxacin in Low-Risk Febrile Neutropenic Adult Patients: A Prospective, Double-blind, Randomized, Non-Inferiority Multicenter, Phase III Clinical Trial. (ACACIA)

Febrile Neutropenia
Nantes University Hospital

Terminated

A Multicenter Randomized Control Trial in Children With Moderate to Severe Atopic Dermatitis to Assess the Benefit of a Nurse-led One-to-one Education Program in Addition to Standard Care Compared to Standard Care Alone on the Long Term Control of Disease Severity at 6 Months (EDUDA)

Dermatitis, Atopic

France
RedHill Biopharma Limited

Available

Expanded Access for the Treatment of Advanced Cholangiocarcinoma With ABC294640 (Yeliva ®)

Cholangiocarcinoma | Cholangiocarcinoma Non-resectable | Cholangiocarcinoma, Perihilar | Cholangiocarcinoma, Extrahepatic | Cholangiocarcinoma, Intrahepatic
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled HIV-1 Vaccine Trial to Evaluate the Safety and Immunogenicity of MN Recombinant Soluble gp120/HIV-1 (rsgp120/HIV-1) (Genentech) in Combination With QS21 Adjuvant and/or Alum in Healthy Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Safety and Immunogenicity of HIV-1 MN rsgp120 and Bivalent AIDSVAX B/E (HIV-1 MN rgp120/A244 rgp120) in Combination With QS-21 With or Without Alum in Healthy HIV-1 Uninfected Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized Trial to Evaluate the Safety and Immunogenicity of Vaccinia-Derived MN HIV-1 Recombinant Envelope Glycoprotein (rgp160) of Human Immunodeficiency Virus at Two Different Vaccination Schedules

HIV Infections | HIV Seronegativity

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized Trial to Evaluate the Safety and Immunogenicity of a Recombinant Vaccinia-HIV Envelope Vaccine (HIVAC-1e) in Combination With a Panel of Subunit Recombinant HIV Envelope Vaccines

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled HIV-1 Vaccine Trial to Evaluate the Safety and Immunogenicity of rgp120/HIV-1MN (Genentech) in Combination With QS21 Adjuvant and/or Alum in Healthy Adults.

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Protein Sciences Corporation

Completed

A Phase I Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Safety and Immunogenicity of HIV-1 Recombinant Envelope Glycoprotein gp160

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized Trial to Evaluate the Safety and Immunogenicity of a Recombinant Vaccinia-HIV Envelope Vaccine (HIVAC-1e) in Combination With a Panel of Subunit Recombinant HIV Envelope Vaccines in Vaccinia-Naive Individuals

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled HIV-1 Vaccine Trial to Evaluate the Safety and Immunogenicity of Low Dose MN rsgp120/HIV-1 (Genentech) in Combination With QS21 Adjuvant or Alum in Healthy Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Three Preparations of Low-Dose Oral Alpha Interferon in HIV-Infected Patients With CD4+ Counts >= 50 and <= 350 Cells/mm3

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Multicenter, Randomized, Double-Blind Trial to Evaluate the Safety and Immunogenicity of Recombinant Vaccinia Virus Expressing the Envelope Glycoproteins of Human Immunodeficiency Virus

HIV Infections

United States
Boston Medical Center
Orthopaedic Trauma Association

Completed

A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Proximal Tibial Fractures

Tibial Fractures

United States, Canada
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blinded, Phase I Trial to Evaluate the Safety and Immunogenicity of Live Recombinant Canarypox ALVAC-HIV vCP205 Combined With GM-CSF in Healthy, HIV-1 Uninfected Volunteers

HIV Infections

United States
Yusup subagio sutanto

Completed

Pedometer Assisted Physical Activity in Individuals With COPD. A Multicenter Randomized Controlled Trial.

Chronic Obstructive Pulmonary Disease (COPD)

Indonesia
National Institute of Allergy and Infectious Diseases...

Withdrawn

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial to Evaluate the Safety and Immunogenicity of an HIV-1 Pseudovirion Vaccine

HIV Infections
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial to Evaluate the Safety and Immunogenicity of the Therion Recombinant Vaccinia-HIV-1 IIIB ENV/GAG/POL Vaccine (TCB-3B) and MN RGP 120/HIV-1 In Alum.

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial to Evaluate the Safety and Immunogenicity of a Recombinant Vaccinia-HIV-1 IIIB Env/Gag/Pol Vaccine (TBC-3B)

HIV Infections

United States
Holy Stone Healthcare Co., Ltd
inVentiv Health Clinical

Completed

A Phase 2a, Multicenter, Randomized, Double-blind, Parallel Group, Placebo-controlled Trial of IBD98-M

Colitis, Ulcerative

Italy
Gachon University Gil Oriental Medical Hospital
Kyung Hee University Hospital at Gangdong; Kyunghee University Medical Center; Sangji University Oriental Medical Hospital and other collaborators

Completed

Efficacy and Safety of Ucha-Shinki-Hwan on Korean Patients With Cold Hypersensitivity in the Hands and Feet-Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial

Cold Hypersensitivity

Korea, Republic of
Annu Navani
Andrews Research & Education Foundation

Completed

The Use of PRP and BMC in Patients With Internal Disc Disruption Multicenter Prospective Randomized Controlled Trial in Patients With Internal Disc Disruption

Internal Disc Disruption

United States
Merck Sharp & Dohme LLC

Terminated

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Trial to Evaluate the Safety, Tolerability, and Efficacy of MK-8457 in Participants With Rheumatoid Arthritis (MK-8457-010)

Rheumatoid Arthritis
Universidade Federal do Rio de Janeiro
Financiadora de Estudos e Projetos; Hospital Universitario Pedro Ernesto; National... and other collaborators

Completed

Nitazoxanide Therapy for Patients With COVID-19 Pneumonia

Pneumonia, Viral | Covid19 | Corona Virus Infection

Brazil
Pfizer

Completed

Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee

Osteoarthritis, Knee

Korea, Republic of, United States
Centro de Educación Medica e Investigaciones Clínicas...

Terminated

Dexamethasone for COVID-19 Related ARDS: a Multicenter, Randomized Clinical Trial

Covid-19 | Respiratory Distress Syndrome, Adult

Argentina
Jaseng Medical Foundation

Completed

Efficacy and Safety of JHG002 for Chronic Temporomandibular Joint Dysfunction: A Multicenter Randomized Controlled Trial

Temporomandibular Disorder

Korea, Republic of
Major Extremity Trauma Research Consortium

Completed

Local Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: A Multicenter Randomized, Controlled Trial (VANCO) (VANCO)

Post Operative Surgical Site Infection

United States
Danderyd Hospital
Uppsala University Hospital

Terminated

Swedish Rectal Prolapse Trial

Rectal Prolapse

Sweden
University Hospital, Angers
Mylan Laboratories

Completed

COvid-19 and Vitamin D Supplementation: a Multicenter Randomized Controlled Trial of High Dose Versus Standard Dose Vitamin D3 in High-risk COVID-19 Patients (CoVitTrial)

Coronavirus

France
Daiichi Sankyo, Inc.

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Study of SUN13834 in Adult Subjects With Atopic Dermatitis

Atopic Dermatitis

United States
Gachon University Gil Oriental Medical Hospital
DongGuk University; Sangji University Oriental Medical Hospital, Korea

Completed

A Pilot Study Exploring the Efficacy and Safety of Herbal Medicine on Korean Obese Women With Metabolic Syndrome Risk Factors - Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial -

Obesity | Metabolic Syndrome

Korea, Republic of
Jason Sperry
Vanderbilt University; University of Texas; Case Western Reserve University; University... and other collaborators

Completed

PreHospital Air Medical Plasma Trial (PAMPer)

Hemmorhagic Shock During Air Medical Transport

United States
Abbott Medical Devices
Cardiovascular Research Foundation, New York

Completed

OPTIMIZE PCI: Multicenter Randomized Trial of OCT Compared to IVUS and Angiography to Guide Coronary Stent Implantation (ILUMIEN III)

Coronary Artery Disease

United States, Spain, Japan, United Kingdom, Germany, Belgium, Italy, Netherlands
Chinese PLA General Hospital

Active, not recruiting

Microwave vs. Radiofrequency Ablation for Benign Thyroid Nodules: A Multicenter Randomized Controlled Trial Study

Ablation | Benign Thyroid Nodules

China

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