Search clinical trials for: suboptimal response

Total 13239 results

Radboud University Medical Center

Not yet recruiting

The Role of the Adrenergic System in Hypoglycaemia Induced Inflammatory Response in People With Type 1 Diabetes and People Without Type 1 Diabetes-RAID-II (RAID-II)

Inflammation | Diabetes Mellitus, Type 1
Instituto Nacional de Cancerologia de Mexico

Recruiting

Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients

Hematologic Neoplasms | Neutropenia

Mexico
University of Santiago de Compostela
Hospital Clinico Universitario de Santiago

Not yet recruiting

An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Procedures

Bacteremia | Endocarditis

Spain
Istituto Clinico Humanitas
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Recruiting

Role of the Maternal Microbiota on the Immune Response and Metabolism During Hypertensive Disorders (MATER)

Preeclampsia

Italy
Changhai Hospital
Shanghai 10th People's Hospital; Ruijin Hospital; Shanghai Ninth People's Hospital... and other collaborators

Not yet recruiting

Real-World Clinical Study on the Efficacy of Vibrating Capsule (Vibrabot Capsule) for Chronic Functional Constipation (RWS-VC)

Clinical Study | Chronic Functional Constipation

China
Hospital Italiano de Buenos Aires

Not yet recruiting

Mortality of MBL-producing Enterobacteriaceae Bacteremias With the Combined Use of Ceftazidime-avibactam and Aztreonam vs. Other Active Antibiotics. A Multicenter Target Trial Emulation.

Bacteremia
Assistance Publique - Hôpitaux de Paris
Institut Pasteur

Recruiting

Physiology and Pathologies Linked to Human Splenic Function : Direct and Ex-vivo Perfusion Explorations (SPLEENVIVO)

Splenectomy

France
University of Udine

Recruiting

Salivary microRNA in Endometriosis: Correlation With Response to Progestin Therapy (ENDOmiRNA)

Endometriosis

Italy
University of Missouri-Columbia

Not yet recruiting

Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia (2100208)

Hypoxia | Menopause | Aging | Vasodilation
M.D. Anderson Cancer Center

Not yet recruiting

18F-AraG PET/CT as a Non-Invasive Imaging Biomarker for Chemoradiation Treatment Response in Esophageal Cancer

Esophageal Cancer

United States
Indonesia University

Not yet recruiting

Comparison Between Split Septum and Mechanical Valve Needleless Connector in Preterm Babies

Sepsis, Neonatal
IRCCS San Raffaele

Recruiting

INfectious DIsease REgistry BIObank (INDI-REBIO)

Central Nervous System Infections | Infective Endocarditis | Vertebral Osteomyelitis | Bone and Joint Infections | Bloodstream Infections | Endovascular Infections | CIED-related Infections

Italy
Pakistan Society for Rehabilitation of Differently...
University of Karachi

Recruiting

Adaptive Response of Brain Towards Resistance Training in Healthy Individuals

Resistance Training

Pakistan
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Recruiting

RISK FACTORS FOR NON-RESPONSE TO HORMONAL MEDICAL THERAPY IN PATIENTS WITH ENDOMETRIOSIS

Endometriosis

Italy
Ruyao Liu

Not yet recruiting

Functional Response Characteristics of Brain Under Swallowing Task Paradigm

Dysphagia | Swallowing Disorder | Swallowing Substances

China
St George's, University of London
MU-JHU CARE; Biomedical Research and Training Institute, Zimbabwe

Recruiting

Using Machine Learning to Model Early-onset Neonatal Sepsis Risk in Uganda and Zimbabwe (NeoRisk)

Neonatal Sepsis

Uganda, United Kingdom
Ankara University
Ankara Yildirim Beyazıt University; Saglik Bilimleri Universitesi; Liv Hospital...

Recruiting

Evaluation of Response by FLT PET in Mesothelioma (FLT-MM)

Chemotherapy Effect | Pleural Mesothelioma | Treatment Response

Turkey
Johns Hopkins University

Recruiting

Using Personalized Assessments in the Treatment of Childhood OCD

Obsessive-Compulsive Disorder

United States
Sanofi

Recruiting

A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Monotherapy Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (ESTUARY)

Dermatitis Atopic

United States
University of Bologna

Not yet recruiting

Effect of a Dietary Supplement on Lipid Pattern, Indexes of NAFLD and Systemic Inflammation in Healthy Subjects With Suboptimal LDL-C Levels

Inflammation | Hypercholesterolemia

Italy
GlaxoSmithKline

Not yet recruiting

Evaluation of Programmed Death Ligand 1 (PDL1) Response to Treatment in Patient-derived Organoids and Immune-marker Positron Emission Tomography (PET) Scanning in Non-small Cell Lung Cancer (NSCLC)

Lung Cancer, Non-Small Cell

United Kingdom
Future Biome SA

Recruiting

Fungal Fiber for Gut Health (FUN4GUT)

Immune Response | Stress | Nutrition, Healthy | Gut Microbiome | Low-grade Chronic Inflammation | Activity of Daily Living | Gut Health | Mild Gastrointestinal Symptoms in Healthy Adults | Gut Permeability

Argentina
York Teaching Hospitals NHS Foundation Trust
University of York; York St John University

Recruiting

CytoHealth - A Study of the Inflammatory Response to Exercise (CytoHealth)

Inflammatory Response | Immune System

United Kingdom
Lisa Carlesso

Not yet recruiting

Physiological Impact of Different Types of Osteoarthritis Education. Education (PNE)

Osteoarthritis | Chronic Pain
Sidney Kimmel Comprehensive Cancer Center at Johns...
Janssen Research & Development, LLC

Not yet recruiting

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Lymphoma | Multiple Myeloma | Hodgkin Lymphoma | Myelofibrosis | Non Hodgkin Lymphoma | Chronic Myeloid Leukemia | Hematologic Malignancy | Aplastic Anemia | Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML) | Bone Marrow Transplant Rejection | Acute Lymphoblastic Leukemia (ALL), Adult
Max-Planck-Institute of Psychiatry

Recruiting

Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression (DECIDE)

Depressive; Disorder, Major, Single Episode, Major, With Psychotic Symptoms | Depressive; Disorder, Major, Single Episode, Major (Without Psychotic Symptoms) | Depressive Disorder, Major, Recurrent, With Psychotic Symptoms | Depressive Disorder, Major, Recurrent, Without Psychotic Symptoms and other conditions

Germany
Universidade Federal Fluminense

Not yet recruiting

Effects of Brazil Nut Supplementation in Patients With Chronic Kidney Disease Undergoing Conservative Treatment

Inflammation | Chronic Kidney Diseases | Inflammatory Response | Oxidative Stress | Chronic Kidney Disease stage4 | Chronic Kidney Disease stage3 | Chronic Kidney Disease Stage 3B | Intestinal Microbiota | Chronic Kidney Disease Stage 3A

Brazil
Adiyaman University

Recruiting

Gram Stain of the First Urine After Puncture in Percutaneous Nephrolithotomy

Percutaneous Nephrolithotomy

Turkey
The Hong Kong Polytechnic University
Health and Medical Research Fund

Recruiting

Intermittent Theta-burst Stimulation for Major Depression: an Intensity-response Study

Depression, Unipolar

Hong Kong
Fudan University

Recruiting

The Study on the Mechanism of Radiotherapy-elicited Immune Response

Radiotherapy | Esophageal Carcinoma Salivary Gland Type

China
Ohio State University Comprehensive Cancer Center

Not yet recruiting

Ketogenic Dietary Intervention to Improve Response to Immunotherapy in Patients With Metastatic Melanoma and Metastatic Kidney Cancer

Metastatic Renal Cell Carcinoma | Metastatic Cutaneous Melanoma | Stage IV Renal Cell Cancer AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC v8

United States
Ferring Pharmaceuticals

Not yet recruiting

A Phase 4, Multi-center, Open Label Trial to Evaluate Efficacy of Retreatment With Nadofaragene Firadenovec in Subjects With CIS ± High-grade Ta/T1 and no Complete Response to First Nadofaragene Firadenovec Dose (ABLE-42)

Bladder Cancer | CIS | Ta/T1
Scipher Medicine

Recruiting

PREDICT Therapy Selection for JAK, T-cell, or IL-6 Inhibitor Therapies Using a Molecular Signature Response Classifier (PREDICT) (PREDICT)

Rheumatoid Arthritis

United States
St. Jude Children's Research Hospital
AbbVie

Not yet recruiting

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

T-cell Lymphoma | T-cell Acute Lymphoblastic Leukemia | Mixed Phenotype Acute Leukemia

United States
Peking Union Medical College Hospital

Not yet recruiting

ICI Rechallenge for Advanced NSCLC With Long-Term Response to First-Line ICI

Non-small Cell Lung Cancer

China
Fundació Sant Joan de Déu
Instituto de Salud Carlos III

Recruiting

Precursors of Binge Eating Disorder in a Clinical Sample of Adolescents With Obesity (PREC-BED)

Obesity | Binge-Eating Disorder | Emotion Regulation | Eating Disorders | Food Addiction | Other Specified Feeding or Eating Disorder | Eating Disorder Nos | BED

Spain
University of Maryland, Baltimore

Recruiting

Protective Arm Balance Responses (PAT)

Peripheral Neuropathy | Old Age; Debility

United States
Cairo University

Recruiting

Plasticity Biomarkers,Interleukin-6 and Motor Performance in Response to Vagus Nerve Stimulation After Stroke

Stroke | Motor Disorders

Egypt
Jorvec Corp.
University of Miami

Recruiting

CLAD Deconvolved PERG Responses in Glaucoma Patients

Glaucoma, Suspect

United States
GlaxoSmithKline

Recruiting

A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus (RSV) Given to Adults 18 to 49 Years of Age at Increased Risk for Respiratory Syncytial Virus Disease, Compared to Older Adults 60 Years of Age and Above

Respiratory Syncytial Virus Infections

United States, Canada, Japan, Germany, Australia, South Africa
AbbVie

Recruiting

A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab (Switch-Up)

Atopic Dermatitis

United States
Dr. Lutfi Kirdar Kartal Training and Research Hospital

Not yet recruiting

Sevoflurane Versus Propofol: Effect on Stress Response

Inflammatory Response | Sevoflurane | Propofol

Turkey
University of Illinois at Urbana-Champaign

Recruiting

Personalized GI Motility Responses to Diet

Cardiovascular Diseases | Dysbiosis | Gastrointestinal Dysfunction | Nutritional and Metabolic Diseases

United States
Ipsen

Not yet recruiting

A Study of Elafibranor in Adults With Primary Biliary Cholangitis and Inadequate Response or Intolerance to Ursodeoxycholic Acid. (ELSPIRE)

Primary Biliary Cholangitis
Istituto Clinico Humanitas
Istituto Ortopedico Rizzoli

Recruiting

Immuno-based Profiling of knEe OA Patients to Predict reSponse to Regenerative Treatment (IMPRESA)

Osteoarthritis, Knee

Italy
Ivan de Kouchkovsky, MD

Not yet recruiting

Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone

Prostate Cancer | High Risk Prostate Carcinoma

United States
Chunling Jiang

Not yet recruiting

Organ Dysfunction Change in Acute Necrotizing Pancreatitis Patients With Sepsis After Open Necrosectomy

Necrotizing Pancreatitis
University of British Columbia
McMaster University

Recruiting

The Acute Effect of Low-intensity Movement Breaks on Glycemic Responses in Individuals With Type 2 Diabetes.

Type 2 Diabetes

Canada
University of British Columbia
McMaster University

Recruiting

The Acute Effect of "Exercise Snacks" on Glycemic Responses in Individuals With Type 2 Diabetes.

Type 2 Diabetes

Canada
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Bayesian Basket Trial (PALETTE)

Sepsis

Search clinical trials for: suboptimal response

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