Search clinical trials for: thrombin

Total 248 results

Kocaeli University

Completed

Application of Thrombin Gel Matrix for the Prevention of Lymphocele in Patients With Endometrial Cancer.

Lymphocele | Lymphocele After Surgical Procedure | Endometrium Cancer

Turkey
Hacettepe University

Completed

The Influence of Tissue Adhesive to Palatal Donor Site Healing.

Donor Site Complication

Turkey
University of Vermont
Janssen Research & Development, LLC

Completed

Novel Biomarkers of Thrombotic Risk

Myocardial Infarction

United States
Asan Medical Center

Unknown

Effect of Thrombin-containing Collagen-based Hemostatic Matrix (TCM)

Pancreatic Tumor

Korea, Republic of
Assiut University

Unknown

Autotaxin (ATX) as a Marker for Breast Cancer

Breast Cancer
Centro Hospitalar de Vila Nova de Gaia/Espinho,...
LEO Pharma; Diagnostica Stago

Unknown

Biomarkers of Thrombosis as Predictors of Venous Thromboembolism Risk in Cancer Patients (FIIT_Score)

Cancer | Thrombosis | Biomarkers | Thromboembolism

Portugal
R&D Cardiologie
St. Antonius Hospital

Unknown

What is the Optimal antiplatElet and Anticoagulant Therapy in Patients With Oral Anticoagulation Undergoing revasculariSaTion 2. (WOEST 2)

Myocardial Infarction | Stroke | Bleeding | Acute Coronary Syndromes | Coronary Artery Diseases | Atrial Fibrillations | Heart Valve Prostheses

Belgium, Netherlands
Tulane University School of Medicine

Completed

Efficacy Study of Activated Prothrombin Complex for Prevention of Bleeds in Hemophilia A With Inhibitors (ProFEIBA)

Hemophilia A With Inhibitors

United States
Mallinckrodt

Terminated

Topical Raplixa for Surgical Bleeding in Children

Surgical Bleeding

United States
University Hospital, Caen
Thong DAO; Annie BOREL-DERLON; Nathalie GANNE-CARRIE; Pierre NAHON; Sylvie Chevret

Completed

Influence of ABO Blood Group on the Risk of Complications in Alcoholic or Viral C Cirrhosis? (ABOCIRRALVIR)

Alcoholic or Viral C Compensated Cirrhosis

France
CirQuest Labs, LLC

Completed

Apixaban + DAPT in Lowering Platelet Reactivity and Thrombin Generation (SEARCH)

Acute Coronary Syndrome

United States
Chang Gung Memorial Hospital

Unknown

Blood-saving Effect of Combined Intravenous Tranexamic Acid With Topical Floseal® Application Total Hip Arthroplasty

Hip Replacement, Total

Taiwan
University of Limerick

Completed

Anti-Inflammatory and Anti-Coagulant Effects of Salmon Polar Lipids

Platelet Thrombus

Ireland
Mallinckrodt

Completed

A Study of Fibrocaps™ in Surgical Bleeding (FINISH-3)

Mild or Moderate Surgical Bleeding

United States, Netherlands, United Kingdom, Belgium
Second Xiangya Hospital of Central South University

Unknown

Bivalirudin in Late PCI for Oatients With STEMI (BETTER)

STEMI - ST Elevation Myocardial Infarction
Baxter Healthcare Corporation

Completed

Efficacy and Safety of TISSEEL Lyo Compared to Manual Compression as an Adjunct to Haemostasis

Adjunct to Hemostasis During Vascular Surgery

Russian Federation
Duke University
Grifols Biologicals, LLC

Completed

Anti-thrombin III (ATIII) vs Placebo in Children (<7mo) Undergoing Open Congenital Cardiac Surgery

ATIII Deficiency

United States
Aronora, Inc.

Completed

Safety and Tolerability Study of E-WE Thrombin in Healthy Adult Subjects

Thrombosis

United States
University Hospital, Gentofte, Copenhagen

Completed

Insulin Sensitivity, Glucose - and Fat Metabolism in Patients With Psoriasis

Insulin Sensitivity | Metabolism Disorder

Denmark
Chang Gung Memorial Hospital

Completed

High-Intensity Interval Training Recuperates Capacity of Endogenous Thrombin Generation in Patients With Heart Failure

Heart Failure | High-intensity Interval Training
Hospices Civils de Lyon

Unknown

TGA (Thrombin Generation Assay) and Prophylaxis in Haemophilia (HOPE)

Haemophilia A

France
Bellal A. Joseph, MD, FACS

Unknown

REPlaCE- Randomized Trial Evaluating the Use of Prothrombin Complex concEntrate to Improve Survival in Patients With Traumatic Coagulopathy (REPLaCE)

Hemorrhage | Coagulopathy
National and Kapodistrian University of Athens

Unknown

Assessment of Blood Coagulation Disorders in Patients With Pulmonary Hypertension

Pulmonary Artery Hypertension | Chronic Thromboembolic Pulmonary Hypertension

Greece
Washington University School of Medicine
Barnes-Jewish Hospital; Canyon Pharmaceuticals, Inc.

Completed

Study Comparing Desirudin With Heparin to Prevent Vein Clots After Heart and Lung Surgery

Deep Venous Thrombosis

United States
East and North Hertfordshire NHS Trust
University of Hertfordshire

Completed

Assessment of The Effect of Apixaban in AF

Atrial Fibrillation | Embolism Thrombosis

United Kingdom
Lund University
Shire

Completed

Evaluation of a Standardized Protocol for Thrombin Generation Assay

Hemophilia A

Sweden
University Hospital, Grenoble

Unknown

Study of Elastographic Properties of the Clot by Technical SWIRE (Shear Wave Induced Resonance Elastography) (ClotStruct)

Deep Vein Thrombosis

France
Biom'Up France SAS

Completed

HEMOBLAST Pivotal Clinical Investigation

Hemostasis

United States
HaEmek Medical Center, Israel

Completed

The Purpose of the Study is to Examine Whether Iron Deficiency Anemia is Associated With Increased Production of Thrombin and Whether Correction of Anemia by Providing Iron Intravenously Causes a Significant Reduction in Production of Thrombin.

Iron Deficiency Anemias

Israel
Motif Bio

Completed

Phase 3 Study to Evaluate Safety and Efficacy of Iclaprim Versus Vancomycin for ABSSSI: REVIVE-2 (REVIVE-2)

Skin Structures and Soft Tissue Infections

United States, Argentina, Belgium, Croatia, Czechia, Estonia, Hungary, Portugal, Romania, Turkey
Medical University of South Carolina
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Safety & Suitability of Dabigatran to Inhibit Thrombin in Scleroderma

Interstitial Lung Disease | Scleroderma

United States
North Texas Veterans Healthcare System

Unknown

Excellence In Peripheral Artery Disease Thrombin Receptor Antagonist Intervention In Claudication Evaluation (XLPAD-TRACE Trial) (XLPADTRACE)

Peripheral Arterial Disease

United States
The Hospital for Sick Children
Synapse B.V. Research Institute, University of Maastricht

Unknown

Point-of-care Assessment of Thrombin Generation and Platelet Function in Children Requiring Cardiopulmonary Bypass

Platelet Function Tests | Thrombin Generation Tests | Perioperative Coagulopathy

Canada
Helsinki University Central Hospital
University of Helsinki

Unknown

Intra-graft Coagulation Events in Clinical Renal Transplantation and Delayed Graft Function (KTX)

End Stage Renal Disease | Kidney Transplantation | Reperfusion Injury | Delayed Graft Function

Finland
HaEmek Medical Center, Israel

Completed

Thrombin Generation and Gestational Outcome

Thrombophilia

Israel
CHU de Reims

Completed

Age-dependency of Thrombin Generation Using a New Standardized Assay (TGT)

Healthy Infants

France
NYU Langone Health
American Heart Association

Completed

Platelet Activity in Vascular Surgery for Thrombosis and Bleeding (PIVOTAL)

Embolism and Thrombosis | Carotid Stenosis | Peripheral Vascular Disease | Peripheral Artery Disease | Aortic Aneurysm, Abdominal | Aortic Aneurysm | Aortic Aneurysm, Thoracic | Amputation, Wound

United States
Hospital for Special Surgery, New York
Baxter Healthcare Corporation

Completed

The Use of FLOSEAL to Reduce Bleeding in Total Knee Replacement Surgery

Blood Loss

United States
University of Witwatersrand, South Africa

Terminated

Safety And Efficacy Of Topical Platelet Rich Plasma And Thrombin Coagulum

Stasis Ulcer

South Africa
Rush University Medical Center
Advocate Health Care

Completed

Fixed-dose Activated Versus Variable-dose Inactivated Prothrombin Complex Concentrate for Warfarin-associated Major Bleed

Hemorrhage
CSL Behring

Completed

Observational Study of Prophylaxis and Treatment of Acute Perioperative Bleeding With Beriplex® P/N (Probe Study)

Coagulation Protein Disorders | Perioperative Care | Blood Loss, Surgical

United Kingdom
Janssen Research & Development, LLC

Completed

A Study to Evaluate Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of JNJ-64179375 in Healthy Male Subjects

Healthy

Belgium
Integra LifeSciences Corporation

Terminated

Study to Evaluate Safety & Effectiveness of Vascular Sealant System

Peripheral Vascular Disease

United States
Lee's Pharmaceutical Limited
Zhaoke Pharmaceutical (Hefei) Company Limited

Unknown

A Clinical Study to Evaluate the Efficacy and Safety of Hemocoagulase Injection

Hemoptysis

China
Asan Medical Center

Unknown

The Effect of Application of TachoSil® in Pancreatoduodenectomy

Pancreatic Neoplasm | Pancreatic Periampullary Cancer | Pancreatic Bordeline Tumor

Korea, Republic of
Wuhan Asia Heart Hospital

Unknown

Thrombotic Biomarkers to Predict Thrombosis in Heparin-induced Thrombocytopenia

Thrombosis | Biomarkers | Heparin-Induced Thrombocytopenia
HaEmek Medical Center, Israel

Completed

Thrombin Generation Test in Patient With Liver Cirrhosis

Cirrhosis

Israel
Instituto Grifols, S.A.

Completed

Safety and Efficacy of Topical Thrombin (Human) Grifols as an Adjunct to Hemostasis During Surgery

Hemostasis

United States
Andrew D. Barreto, MD
The University of Texas Health Science Center, Houston

Terminated

Randomized Controlled Trial of Argatroban With Tissue Plasminogen Activator (tPA) for Acute Stroke (ARTSS-2)

Ischemic Stroke

United States
Centre Hospitalier Universitaire de Saint Etienne
LEO Pharma

Completed

Effects of Anticoagulant Preventive Injection in Patients With Blood Cancer (METRO B)

Lymphoma | Multiple Myeloma

France

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