Search clinical trials for: TD-6450

Total 5918 results

Tanox

Unknown

Safety and Efficacy Study of TNX-650 to Treat Refractory Hodgkin's Lymphoma

Hodgkin's Lymphoma

United States
Advocate Health Care

Completed

The Impact of Cytochrome P450 Abnormalities in Patients With Delirium.

Delirium, Cytochrome P-450 Enzyme System

United States
GlaxoSmithKline

Completed

Immunogenicity and Reactogenicity Study of BoostrixTM (dTpa) and Boostrix-IPV (dTpa-IPV)

Tetanus | Diphtheria | Acellular Pertussis

Spain, Netherlands, Belgium
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

Effect of Rifampin and Efavirenz on the Pharmacokinetics of Fedratinib in Healthy Adult Subjects

Healthy Volunteers

United States
Debiopharm International SA

Completed

A Multiple Dose Study of Debio 1450 [Intravenous (IV) and Oral] in Healthy Volunteers

Bacterial Infections

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety of FXR-450 in Healthy Subjects

Healthy

United States
Debiopharm International SA

Completed

Mass Balance Recovery and Metabolic Profile of 14C Debio 1450 Following Single Oral and Intravenous Doses in Healthy Male Subjects

Healthy

United Kingdom
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Evaluating FXR-450 in Healthy Japanese Men

Healthy

Japan
Johns Hopkins University
University of Cape Town Lung Institute; University of Cape Town

Completed

Study of Daily Rifapentine for Pulmonary Tuberculosis

Tuberculosis

South Africa
Kirby Institute
Chelsea and Westminster NHS Foundation Trust

Completed

The Intensive Pharmacokinetics Sub-study of Encore1 (ENCORE1-PK)

HIV Infection

Argentina, South Africa, Thailand, United Kingdom
Sociedad Andaluza de Enfermedades Infecciosas
Consejeria de Salud. Junta de Andalucia. Spain

Completed

Incidence and Severity of Neuropsychiatric Adverse Events of Efavirenz Given as a Stepped Dosage vs. the Usual Dosage

HIV Infection | HIV-1 Infection

Spain
Kirby Institute
The HIV Netherlands Australia Thailand Research Collaboration

Completed

The Neurocognitive Sub-study of Encore1

HIV

Thailand
Bristol-Myers Squibb
Truven health

Completed

Risk of CV Events With EFV vs. EFV-free Regimens

HIV/AIDS
Kirby Institute
Imperial College London

Completed

The Efavirenz (EFV) Central Nervous System Exposure Sub-study of Encore1 (ENCORE1-CNS)

HIV Infection

Thailand, Germany, United Kingdom
Kyowa Kirin Co., Ltd.

Completed

A Drug Interaction Study of KW-6356 and Clarithromycin or Rifampicin

Parkinson's Disease

Japan
Reata, a wholly owned subsidiary of Biogen
Celerion; Q2 Solutions; Altasciences Company Inc.

Completed

An Open-label DDI Study of Omaveloxolone in Healthy Subjects

Healthy Adult Subjects

United States
Case Western Reserve University
Massachusetts General Hospital; University Hospitals Cleveland Medical Center

Completed

Efavirenz for Patients With Alzheimer's Disease (EPAD)

Alzheimer Disease, Early Onset

United States
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of a Moderate CYP3A Inducer Efavirenz on Quizartinib Pharmacokinetics in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Institut Bergonié

Completed

Efavirenz in Treating Patients With Metastatic Prostate Cancer (FAVE)

Prostate Cancer

France
Johns Hopkins University
American College of Obstetricians and Gynecologists; The Campbell Foundation

Terminated

Pharmacokinetics and Pharmacodynamics of the Etonogestrel Contraceptive Implant When Co-administered With Efavirenz

Drug Interaction

United States
Oswaldo Cruz Foundation
Ministry of Health, Brazil

Terminated

Randomized Clinical Trial to Assess the Efficacy and Safety of Concomitant Use of Rifampicin and Efavirenz 600 X 800mg (IPEC-EFV)

HIV Infections | Tuberculosis

Brazil
Mahidol University

Unknown

Influence of Cytochrome P2B6 on Efavirenz Dose in HIV-infected Thai Patients

HIV | Cytochrome P-450 CYP2B6 | Efavirenz

Thailand
University Hospital, Geneva
University Hospital, Basel, Switzerland; University of Lausanne Hospitals; University... and other collaborators

Completed

Patient Preference, Sleep Quality, and Anxiety/Depression: A Randomized Comparison of Etravirine and Efavirenz (SWITCH-EE)

Sleep Disorders

Switzerland
Shanghai Public Health Clinical Center

Not yet recruiting

Efficacy of 400 mg Efavirenz Versus Standard 600 mg Dose in HIV/TB Co-infected Patients

HIV Infections | Tuberculosis
University of Nebraska

Completed

EFV Pharmacokinetics & Pharmacogenomics in Older HIV-infected Patients (EFV)

HIV Infection

United States
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A Trial of DDI Between SHR1459 and Efavirenz With Healthy Subjects

B-cell Tumors

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Study of SHR6390 on Healthy Chinese Volunteers

Advanced Solid Tumor

China
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Tolerability, and Effect of TMC207 and Efavirenz in Healthy Volunteers

HIV | Tuberculosis

United States
The HIV Netherlands Australia Thailand Research...
Ministry of Education, Thailand

Completed

A Pharmacokinetic Study of Once Daily Efavirenz 400 mg Versus 600 mg in Thai HIV-1 Infected Subjects

HIV Infections

Thailand
Indiana University

Completed

Effects of CYP2B6 Genetic Polymorphisms on Efavirenz Pharmacokinetics

HIV

United States
Annemieke Geluk
The Leprosy Mission Bangladesh

Recruiting

Novel Interventions and Diagnostic Tests for Leprosy (INDIGO#2)

Leprosy

Bangladesh
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A Drug-drug Interaction Study of SHR2150 on Healthy Chinese Volunteers

Human Immunodeficiency Virus Infection

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Drug-Drug Interaction of Pyrotinib With a Moderate CYP3A Inducer

Healthy Subjects, Drug-drug Interaction, Pyrotinib

China
Peking Union Medical College Hospital
National Key Technologies R&D Program for the 13th Five-year Plan; National... and other collaborators

Completed

Efavirenz 400mg in Treatment-naïve Chinese HIV-infected Patients

HIV-1-infection

China
Fondo Nacional de Desarrollo Científico y Tecnológico...

Completed

A Randomized Clinical Trial for Depressed Mothers at Primary Care Level (DMH)

Depression

Chile
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Efavirenz (EFV) in HIV-Infected and HIV/Tuberculosis (TB) Coinfected Children

HIV Infections | Tuberculosis

South Africa, Zimbabwe, India, Uganda
Debiopharm International SA

Completed

Drug Penetration Into Bone After Repeated Oral Administration of Debio 1450 to Patients Undergoing Hip Replacement Surgery

Bone Diseases, Infectious

United States
Gilead Sciences

Terminated

Efficacy and Safety Study of GS-9450 Treatment for 6 Months in Patients With Chronic Hepatitis C Virus Infection

HCV Infection

United States, United Kingdom, Germany, Canada, Puerto Rico, Poland
Medical Imaging Informatics Research Centre at...

Unknown

Tomosynthesis Use in Detecting Subtle Occult Hip Fractures

Hip Fracture

Canada
Sanofi

Completed

Study of Drug-drug Interaction of the Effects of Gemfibrozil and Rifampicin on SAR442168 in Healthy Adult Subjects

Multiple Sclerosis

United States
Eisai Inc.

Completed

Study to Assess Pharmacokinetic Drug-Drug Interaction Between Avatrombopag When Co-Administered With Fluconazole, Itraconazole, or Rifampin in Healthy Subjects

Healthy Participants

United States
Tourcoing Hospital

Recruiting

Rifabutin Versus Rifampicin for Treatment of Staphylococcal PJI Treated With DAIR (RIFAMAB)

Prosthetic Infection

France
University of Cape Town

Recruiting

High vs. Standard Dose Rifampicin for Effusive Tuberculous Pericarditis (IMPI-3)

HIV Status | Tuberculous Pericarditis

South Africa
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test Whether Rifampicin Influences the Amount of BI 894416 in the Blood

Healthy

Germany
Rennes University Hospital

Completed

EVRIOS : Comparative Evaluation of Low Versus High Doses of Rifampicin (EVRIOS)

Osteoarticular Infection

France
Jiangsu HengRui Medicine Co., Ltd.

Completed

Drug-Drug Interaction of SHR1459 With a Strong CYP3A Index Inducer (Rifampicin)

Healthy Subjects, Drug-drug Interaction, Pharmacokinetics, SHR1459

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Rifampin Effect Study of SHR2554 on Healthy Chinese Adult Subjects

Healthy

China
Peking Union Medical College Hospital

Unknown

Efficacy of Efavirenz 400mg vs. 600mg Combined With Lamivudine and Tenofovir in Treatment Naive HIV Infection

HIV/AIDS | Mental Impairment

China
AstraZeneca

Completed

A Study in Healthy Subjects to Assess the Pharmacokinetics of Savolitinib When Administered Alone and in Combination With Rifampicin

Solid Tumors

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Trial of Rifampicin Pharmacokinetics Effect on Fluzoparib

Healthy Male Subjects

China

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