Clinical Trials Sponsored by LENA Foundation

Total 16262 results

Siyang Leng

Completed

Carfilzomib With Bendamustine and Dexamethasone in Multiple Myeloma

Multiple Myeloma

United States
Regina Elena Cancer Institute

Completed

The Effects of TAP Block on Postsurgical Pain After Minimally Invasive Partial Nephrectomy:

Chronic Pain | Acute Pain

Italy
Regina Elena Cancer Institute

Completed

Goal Directed Therapy (GDT) in Cytoreductive Surgery (CRS) and Hyperthermic Intra Peritoneal Chemotherapy (Hipec)

Primary Peritoneal Neoplasm | Secondary Peritoneal Neoplasm

Italy
Regina Elena Cancer Institute

Completed

Sevoflurane Protective Effect on Ischemia Reperfusion Injury in Microvascular Surgery

Microvascular Breast Flap in Plastic Surgery

Italy
Regina Elena Cancer Institute

Unknown

Targeting the Hippo Transducer TAZ in Breast Cancer With Statins (TRINACRIA)

Breast Neoplasms
South Valley University
Ibn Sina Hospital; Qena Fertility Center, Qena, Egypt

Unknown

Comparative Study of Three Different Embryo Transfer Media in ICSI Cycles

Improvement of Embryo Transfer Technique | Improvement of Implantation
Jena University Hospital
Zentrum für Klinische Studien Jena; Aachen Resonance GmbH

Completed

Elutax-SV Drug-eluting Balloons for Below-the-knee Treatment (Apollo)

Peripheral Artery Disease | Critical Limb Ischemia

Germany
Lene V. Ravn-Nielsen
University of Southern Denmark; The Hospitals Pharmacies' and Amgros' Research... and other collaborators

Completed

The Pharmacist Follows You and Your Medication From Hospital to Your Daily Life and Investigate What This Means to You

Cross-Sectional Study
Christian Schulze

Recruiting

ECMOsorb Trial - Impact of a VA-ECMO in Combination With CytoSorb in Critically Ill Patients With Cardiogenic Shock (ECMOsorb)

Cardiogenic Shock

Germany
Lenar Yessayan

Suspended

SCD for CRS in Congestive Heart Failure (CHF) (No Left Ventricular Assist Device)

Heart Failure | Renal Failure | Chronic Systolic Heart Failure | Cardiorenal Syndrome

United States
LENZ Therapeutics, Inc
ORA, Inc.

Completed

Evaluation of the Safety and Effectiveness of Aceclidine/Brimonidine (LNZ101) and Aceclidine (LNZ100) in the Treatment of Presbyopia

Eye Diseases | Refractive Errors | Presbyopia

United States
Jena University Hospital
GE Healthcare

Unknown

Fusion UltraSound Imaging Of the Thyroid GlaNd With I-124 PET. Evaluation of Nodule Allocation. (FUSION iENA)

Thyroid Diseases | Thyroid Nodule | Thyroid Goitre

Germany
LENZ Therapeutics, Inc
ORA, Inc.

Completed

Phase 3 Evaluation of the Safety and Efficacy of LNZ101 for the Treatment of Presbyopia (CLARITY)

Eye Diseases | Refractive Error | Presbyopia | Miosis | Near Vision

United States
Lenar Yessayan

Suspended

Selective Cytopheretic Device (SCD) Trial

Cardiorenal Syndrome | Acute on Chronic Systolic Congestive Heart Failure

United States
Lene Meldgaard Knudsen

Completed

Vaccination With PD-L1 Peptide Against Multiple Myeloma

Multiple Myeloma

Denmark
Jena University Hospital
Aesculap AG

Completed

Comparison of Skin Adhesive to Subcuticular Suture Wound Closure After Port Placement (PWC)

Wound Closure After Port Catheter Implantation

Germany
University of Jena
KKS Netzwerk

Terminated

Comparison of Paclitaxel-Coated Balloons Against Drug-Eluting Bioresorbable Scaffolds for Elective PCI Using OCT (OCTOPUS-3)

Coronary Artery Disease

Germany
Regina Elena Cancer Institute
AstraZeneca

Unknown

A Study, Comparing a Dose-Titration Regimen of Fulvestrant With the Approved Dosing Regimen in Postmenopausal Patients With Hormone-Responsive Advanced Breast Cancer (ABC) (FIDeS)

Breast Cancer

Italy
Christian Schulze
Boehringer Ingelheim; Zentrum für Klinische Studien Jena

Completed

Effects of Empagliflozin on Diuresis and Renal Function in Patients With Acute Decompensated Heart Failure (EMPAG-HF)

Acute Decompensated Heart Failure

Germany
Lina Sharab

Recruiting

Pain and Activity Levels After Orthodontic Separators

Dental Malocclusion

United States
Lenar Yessayan

Recruiting

The Selective Cytopheretic Device (SCD) for Acute Kidney Injury (AKI) and Hepatorenal Syndrome (HRS) Type I

Acute Kidney Injury | Hepatorenal Syndrome

United States
Northumbria University
Iprona Lana SpA

Completed

Recovery With Tart Cherry Supplementation Following a Marathon.

Exercise Recovery

United Kingdom
LENZ Therapeutics, Inc
ORA, Inc.

Completed

Phase 3 Safety Study for the Treatment of Presbyopia Subjects

Eye Diseases | Presbyopia | Miosis | Near Vision

United States
LENZ Therapeutics, Inc
ORA, Inc.

Completed

Phase 3 Efficacy Study of LNZ101 for the Treatment of Presbyopia (CLARITY)

Eye Diseases | Presbyopia | Miosis | Near Vision

United States
LENZ Therapeutics, Inc
ORA, Inc.

Completed

Plasma Pharmacokinetics and Safety of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Subjects With Presbyopia

Eye Diseases | Refractive Errors | Presbyopia | Ophthalmic Solutions | Brimonidine Tartrate | Aceclidine

United States
University of Applied Sciences Jena

Completed

Night Myopia and Dark Focus of Accommodation

Dark Focus of Accommodation

Germany
Lene Holmvang
AstraZeneca

Completed

Ticagrelor for the Comatose (TICOMA)

Comatose

Denmark
Sebastian Zingler

Completed

Mechanical Plaque Control and Gingivitis Reduction in Fixed Appliance Patients

Gingivitis | Dental Plaque

Germany
Heidelberg University
University of Jena

Completed

Structured Patient Education and Quality of Life of Elderly Patients With Diabetes Mellitus- a Prospective Study

Insulin Therapy | Metabolic Control | Impact of Structured DTTP on Quality of Life | Psychological Aspects
Heidelberg University
German Research Foundation; Universitätsklinikum Düsseldorf; Psychologische Hochschule... and other collaborators

Recruiting

Mentalization-based Treatment Versus Bona-fide Treatment for Patients With Borderline Personality Disorder in Germany (MAGNET)

Borderline Personality Disorder

Germany
ENA Respiratory Pty Ltd

Withdrawn

Intranasal INNA-051 for Prevention of COVID-19 in Adults

COVID-19 Pandemic
ENA Respiratory Pty Ltd

Completed

INNA-051 Influenza Challenge Study

Influenza Prophylaxis

United Kingdom
University of Jena
Medical University Innsbruck

Completed

Effects of Kalydeco on Upper Airway and Paranasal Sinus Inflammation Measured by Nasal Lavage and on Symptoms (KPNSI)

Inflammatory Changes in Epithelial Lining Fluid Sampled Non-invasively by Nasal Lavage in CF Patients With G551D Receiving Kalydeco

Germany
Lina Xu

Completed

A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis

Osteoarthritis of the Knee

United States
Lena Bornhoft
Region Västra Götaland, Sweden; Region Värmland, Sweden

Completed

Prevention of Lifestyle-related Ill-health With Early Functional Examinations and Individualized Risk Profiles (PREVFUNKTION)

Lifestyle Risk Reduction

Sweden
sena ozdemir

Completed

Reliability And Validity Of The Usage Of The Camry Dynamometer In Healthy Adults

Hand Grasp

Turkey
Jena University Hospital
Boston Scientific Corporation

Completed

Embozene® Microspheres for Prostatic Arterial Embolization in Patients With Symptomatic Benign Prostatic Hyperplasia (EmboProstate)

Benign Prostatic Hyperplasia

Germany
Regina Elena Cancer Institute
Intuitive Surgical

Completed

Time Efficiency of Intracorporeal Orthotopic Diversion With Robotic Staplers After Robot Assisted Radical Cystectomy

Robotic Surgical Procedures | Cystectomy | Surgical Staplers

Italy
Hannover Medical School
University of Jena

Unknown

Systematic Study of Parameters of Chronic Kidney Disease Mineral and Bone Disorder (CKD-MBD) (BoneX)

Renal Osteodystrophy

Germany
Lene Boesby
Rigshospitalet, Denmark

Completed

Inhibition of Aldosterone in Patients With Chronic Renal Disease

Kidney Failure, Chronic

Denmark
Thrombologic ApS
Rigshospitalet, Denmark; Lene Holmvang

Completed

Ilomedin Treatment for Patients Having Undergone Primary Percutaneous Coronary Intervention (PCI)

Myocardial Infarct

Denmark
Lina Zhang
Zhejiang Chinese Medical University

Not yet recruiting

Effect of Indoor Plants on Cardiopulmonary System

Cardiopulmonary
University of Leipzig
Jena University Hospital

Recruiting

Acute Impact of the Impella CP Assist Device in Pts. With Cardiogenic Shock on the Patients Hemodynamic (JenaMACS)

Cardiogenic Shock

Germany
Jena University Hospital
University Hospital Tuebingen

Recruiting

Living Donor Liver Transplantation With Two Stage Hepatectomy for Patients With Isolated, Irresectable Colorectal Liver Metastases (LIVERT(W)OHEAL)

Colorectal Cancer Metastatic | Liver Metastases

Germany
Technische Universität Dresden
Jena University Hospital

Active, not recruiting

Inter- and Multidisciplinary, Cross-sectoral Feto-neonatal Pathway

Pre-Eclampsia | Intrauterine Growth Restriction | Maternal Care for Known or Suspected Poor Fetal Growth

Germany
University of Leipzig
University of Jena

Active, not recruiting

Impact of Left Atrial Appendage Closure on Physical Capacity. (LAAEX)

Atrial Fibrillation

Germany
Jena University Hospital
University Hospital Goettingen

Unknown

International Registry on the Use of the CytoSorb Adsorber (CytoSorb)

Sepsis | Need of Cardiac Surgery

Germany, Hungary, Austria
University of Leipzig
University of Jena

Completed

Time-Dependent Mobilization of Circulating Progenitor Cells During Strenuous Exercise in Healthy Individuals

Healthy Men

Germany
Lene Boesby
Rigshospitalet, Denmark

Terminated

Aldosterone Blockade in Chronic Kidney Disease: Influence on Arterial Stiffness and Kidney Function (ALBLOCK-2)

Chronic Kidney Disease

Denmark
University of Leipzig
University of Jena

Completed

Changes of Biomarkers in Response to Training and Antioxidant Treatment

Obesity | Type 2 Diabetes

Germany

Clinical Trials Sponsored by LENA Foundation

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