Night Myopia and Dark Focus of Accommodation

November 29, 2017 updated by: Philipp Hessler, University of Applied Sciences Jena

Influence of an Imaginary Target on the State of Accommodation Under Scotopic Conditions

Shifts in accommodation at decreasing luminance levels are considered as principle cause for night myopia. Previous studies with laser optometers quantified the dark focus of accommodation up to 3 D. In addition to the measurement of dark focus, the aim of this study was to investigate the influence of an imaginary target at finite distances on the state of accommodation at scotopic luminance.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Accommodation was measured by using an open-field autorefractor (WAM 5500, GRAND SEIKO). Full corrected right eyes of 39 subjects aged from 18 to 40 years were investigated in this randomized, cross-sectional study. Accommodation measurements in photopic luminance were taken for 6 m of empty field and for optotype fixation at 2 m, 1 m and 0.5 m. At scotopic luminance, dark focus of accommodation was examined directly after darkening and after 10 min of dark adaptation. After adaptation, subjects had to visualize imaginary targets in the four distances while accommodation was measured.

Study Type

Interventional

Enrollment (Actual)

39

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Germany
    • TH
      • Jena, TH, Germany, 07745
        • University of applied sciences

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

22 years to 39 years (ADULT)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • age 18 - 44
  • visual acuity at least 0.8 (5/6)

Exclusion Criteria:

  • medication with an impact on the visual system
  • visual disease or disease with an impact on the visual system
  • pregnancy or other hormonal variances
  • drug usage
  • overfatigue at the period of investigation
  • mental handicap

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: BASIC_SCIENCE
  • Allocation: RANDOMIZED
  • Interventional Model: SINGLE_GROUP
  • Masking: NONE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
EXPERIMENTAL: Accommodation in scotopic luminance
Diagnostic test: Accommodation Measurement
Accommodation was measured for different distances and light conditions.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Shift of accommodation in scotopic luminance (Dark focus)
Time Frame: Baseline only
Accommodative shift in scotopic luminance compared to photopic luminance for empty field (dark focus of accommodation)
Baseline only

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Difference of accommodation for 2 m target
Time Frame: Baseline only
Accommodative shift in scotopic luminance compared to photopic luminance for the fixation of a target in 2 m
Baseline only
Difference of accommodation for 1 m target
Time Frame: Baseline only
Accommodative shift in scotopic luminance compared to photopic luminance for the fixation of a target in 1 m
Baseline only
Difference of accommodation for 0.5 m target
Time Frame: Baseline only
Accommodative shift in scotopic luminance compared to photopic luminance for the fixation of a target in 0.5 m
Baseline only

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Applied Sciences Jena

Investigators

  • Principal Investigator: Philipp Hessler, M.Sc., University of Applied Sciences Jena

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

February 2, 2017

Primary Completion (ACTUAL)

March 23, 2017

Study Completion (ACTUAL)

March 23, 2017

Study Registration Dates

First Submitted

November 26, 2017

First Submitted That Met QC Criteria

November 29, 2017

First Posted (ACTUAL)

November 30, 2017

Study Record Updates

Last Update Posted (ACTUAL)

November 30, 2017

Last Update Submitted That Met QC Criteria

November 29, 2017

Last Verified

November 1, 2017

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • UASJena

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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