Search clinical trials for: LPS sequestration

Total 276 results

Barmherzige Brüder Linz

Completed

Possible Links Between Inflammation and Lipid Metabolism

Sepsis | Inflammation | Lipid Metabolism Disorder | LPS

Austria
Sanofi

Completed

Efficacy and Safety of Toujeo® Versus Tresiba® in Insulin-Naive Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Oral Antihyperglycemic Drug(s) ± GLP-1 Receptor Agonist (BRIGHT)

Diabetes Mellitus, Type 2

Israel, Czechia, Greece, Italy, United States, Bulgaria, Croatia, Denmark, France, Hungary, Romania, Serbia, Slovakia, Sweden, Switzerland, United Kingdom
Jesus Moreta Suarez

Active, not recruiting

Hybrid Versus Cemented TKA Using the NexGen LPS Prosthesis

Total Knee Arthroplasty

Spain
Nova Scotia Health Authority
Arthrex, Inc.

Completed

Prospective, Multi-Center Clinical Evaluation of the Open Wedge Osteotomy and Low Profile Plate & Screw (LPS) System Compared to the Proximal Chevron Osteotomy for the Treatment of Hallux Valgus With an Increased Intermetatarsal Angle (Hallux valgus)

Hallux Valgus

Canada
Campus Bio-Medico University

Unknown

Role of Curarization During Anesthesia for Gynecologic Surgical Laparoscopic Procedures

Curarization, Postoperative Residual

Italy
Karolinska Institutet
The Swedish Research Council; University of California, San Francisco; Swedish... and other collaborators

Completed

Inflammation and Brain Function - Main Study

Sickness Behavior
Karolinska Institutet
The Swedish Research Council; University of California, San Francisco; Swedish... and other collaborators

Completed

Inflammation and Brain Function - Pilot Study

Sickness Behavior
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Development of Novel Non-invasive Inflammometry Following Lipopolysaccharide, Endotoxin (LPS) Challenge in Healthy Volunteers

Healthy

Germany
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Alirocumab Versus Placebo on Top of Maximally Tolerated Lipid Lowering Therapy in Patients With Hypercholesterolemia Who Have Type 1 or Type 2 Diabetes and Are Treated With Insulin (ODYSSEY DM - Insulin)

Hypercholesterolaemia

Belgium, Spain, Germany, Austria, Italy, United States, France, Netherlands, Switzerland, United Kingdom
Genzyme, a Sanofi Company

Completed

Efficacy and Tolerability of ZD6474 in Patients With Thyroid Cancer

Thyroid Cancer

United States, France
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Alirocumab Versus Usual Care on Top of Maximally Tolerated Statin Therapy in Patients With Type 2 Diabetes and Mixed Dyslipidemia (ODYSSEY DM-Dyslipidemia)

Dyslipidemia

United States, Australia, Brazil, Finland, Germany, Israel, Italy, Kuwait, Lebanon, Norway, Sweden, Switzerland, Turkey, United Arab Emirates, United Kingdom
University of Nottingham

Completed

Effect of Lipopolysaccharide on Skeletal Muscle Functions (LPS)

Sepsis

United Kingdom
dora pereira
University of Oxford; University of Cambridge; Bangor University

Completed

Health Economics of the Use of Ferrous Iron Salts in Primary Care in the UK.

Anemia

United Kingdom
Alteco Medical AB
Uppsala University; TFS Trial Form Support

Terminated

ASSET - a Double-Blind, Randomized Placebo-Controlled Clinical Investigation With Alteco® LPS Adsorber (ASSET)

Septic Shock

Finland, Norway, Sweden
Cutera Inc.

Completed

Laser Removal of Age (Sun) Spots on Hands

Solar Lentigines

United States
Genzyme, a Sanofi Company

Completed

A Phase II Study of 2 Doses of ZD6474 (Vandetanib) in Combination With FOLFOX vs FOLFOX Alone for the Treatment of Colorectal Cancer

Cancer | Colorectal

Korea, Republic of, Spain, Hungary, Slovakia, Taiwan, France
University of North Carolina, Chapel Hill
National Institute of Environmental Health Sciences (NIEHS); Purdue University

Completed

Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled LPS (Vitalps)

Mild, Allergic Asthma

United States
GlaxoSmithKline

Completed

Endotoxin Challenge Study For Healthy Men and Women

Pulmonary Disease, Chronic Obstructive

Germany
Baylor Research Institute

Withdrawn

Intratumoral Dendritic Cell Vaccination Combined With Local Radiotherapy in Patients With Recurrent Lymphoma.

Lymphoma
University Hospital, Gentofte, Copenhagen
Sanofi

Completed

Effect of Bile Acid Secretion and Sequestration on GLP-1 Secretion

Diabetes Mellitus, Type 2

Denmark
Robert J Noveck, M.D.
Foundation for the National Institutes of Health

Completed

Dose-Related Inflammatory Effects of Intravenous Endotoxin in Humans

Healthy

United States
Moerae Matrix, Inc.

Unknown

Phase 1a Study in Healthy Smokers to Investigate the Effect With MMI-0100 on Airway Inflammation in Induced Sputum After Challenge With Inhaled Lipopolysaccharide (LPS)

Acute Inflammatory Response to Non-antigenic Stimulus

United Kingdom
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Inflammation and the Metabolic Syndrome in Humans (LPS)

Metabolic Syndrome X

United States
Sanofi

Completed

Using Patient Reported Outcomes (PROs) to Evaluate Teriflunomide Treatment in Relapsing Multiple Sclerosis (RMS) Patients (TERI-PRO)

Multiple Sclerosis

Finland, Belgium, Spain, Chile, Norway, Italy, United States, Austria, Canada, France, Germany, Greece, Sweden, United Kingdom
University Magna Graecia

Unknown

Ovarian Reserve Modification After Lps Hysterectomy With Bilateral Salpingectomy

Pelvic Pain | Adenomyosis | Uterine Fibroids | Pelvic Prolapse

Italy
Queen's University
Zimmer Biomet

Terminated

Computer-assisted Total Knee Arthroplasty (TKA) With Zimmer LPS Flex Knee System

Knee Arthroplasty
Northwest Women's and Children's Hospital, Xi'an...

Unknown

Gonadotrophin Releasing Hormone Agonist Addition for Luteal Support in In-vitro Fertilization and Embryo Transfer Cycles

GnRHa;LPS
HaEmek Medical Center, Israel
University of Zurich; University of Palermo

Terminated

Lipids Profile in Subclinical Hypothyroidism (LPSH)

Subclinical Hypothyroidism

Israel
Craig L Slingluff, Jr
National Cancer Institute (NCI); University of Virginia; Oncovir, Inc.

Completed

A Multipeptide Vaccine Plus Toll-Like Receptor Agonists in Melanoma Patients (MEL58)

Melanoma

United States
Pfizer

Terminated

A Study To Evaluate The Safety And Effects On The Body Of An Investigational Drug Using An Endotoxin-Induced Inflammatory Response Model (POM)

Healthy

United States
Radboud University Medical Center
Exponential Biotherapies Inc.

Completed

PK/PD of EA-230 During Endotoxemia

Endotoxemia | Systemic Inflammatory Response

Netherlands
Genzyme, a Sanofi Company

Completed

Management Of The Infusion-Associated Reactions In RRMS Patients Treated With LEMTRADA (EMERALD)

Relapsing-remitting Multiple Sclerosis

Belgium, Spain, France, Netherlands
Royal Brompton & Harefield NHS Foundation Trust

Terminated

Sequestration of Platelets Prior to Bypass Reduces Bleeding After Cardiac Surgery

Blood Coagulation Disorders | Blood Platelet Disorders | Cardiopulmonary Bypass | Cardiac Surgical Procedures

United Kingdom
Radboud University Medical Center

Completed

the Influence of Remote Ischemic Preconditioning on Inflammation During Human Endotoxemia (RISPENDO)

Autoimmune Diseases | Infection

Netherlands
University of Aberdeen

Completed

Whey Protein Study - Identification of Sustainable Satiety

Satiety

United Kingdom
University of Michigan
Centers for Disease Control and Prevention

Completed

A Study of Exclusion Criteria in a University Population (eX-FLU)

Influenza

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

The Role of the Gut Microbiota in the Systemic Immune Response During Human Endotoxemia (MISSION-2)

Endotoxemia

Netherlands
Radboud University Medical Center

Completed

Ticagrelor in Human Endotoxemia Response to Human Endotoxemia

Endotoxemia

Netherlands
The University of Hong Kong

Completed

A Study of Human Chorionic Gonadotrophin as Luteal Phase Support in Frozen Embryo Transfer

Subfertility

Hong Kong
University of Aarhus

Completed

A Study of Intracellular Signaling in Muscle and Fat Cells During Ketosis

Diabetes Mellitus Type 1 | Ketoacidosis

Denmark
University Hospital, Gentofte, Copenhagen
Sanofi

Completed

Effect of Bile Acid Sequestration on Postprandial GLP-1 Secretion, Glucose Homeostasis and Gut Microbiota

Type 2 Diabetes

Denmark
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Effects of Iron Loading and Iron Chelation Therapy on Innate Immunity During Human Endotoxemia

Anemia | Systemic Inflammatory Process
Karolinska Institutet
Danderyd Hospital

Completed

Endotoxin-induced Inflammatory and Behavioral Responses and Predictors of Individual Differences

Sickness Behavior
Radboud University Medical Center

Completed

The Effects of Atazanavir-induced Hyperbilirubinemia During Human Endotoxemia

Sepsis | Inflammation | Endotoxemia | Multi Organ Dysfunction Syndrome

Netherlands
Merck Sharp & Dohme LLC

Completed

Study of Biomarkers of Airway Inflammation (0000-128)

Airway Inflammation
Rutgers, The State University of New Jersey

Completed

The Effects of Epinephrine in Endotoxemia in Normal Volunteers (Epi)

Immune System

United States
Radboud University Medical Center

Completed

Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1α

Hypoxia | Hyperoxia | Normoxia

Netherlands
Radboud University Medical Center

Completed

Effects of BCG on Immune Response

Sepsis

Netherlands
The Third Affiliated Hospital of Southern Medical...

Unknown

The Mechanisms and Significances of Synergistic Effects of Mycophenolic Acid and LPS on IL-1β Secretion by Mononuclear

Lupus Nephritis

China
Monash University
Lam Wah Ee Hospital

Completed

Adjunct Inversion for Lower Pole Stone

Kidney Stone

Search clinical trials for: LPS sequestration

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