Search clinical trials for: Opdivo®

Total 20879 results

Merck Sharp & Dohme LLC
Pfizer

Completed

Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)

Type 2 Diabetes Mellitus
Stiefel, a GSK Company
GlaxoSmithKline

Completed

Two-week Study to Compare the Tolerance and Irritation Potential of Two Combination Topical Gel Acne Medications

Acne Vulgaris

United States
AbbVie (prior sponsor, Abbott)
Quintiles, Inc.

Completed

Study of Efficacy, Safety and Tolerability of Levodopa-Carbidopa Intestinal Gel in Levodopa-Responsive Parkinson's Subjects

Advanced Parkinson's Disease

United States, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Cancer

United States, Australia
Teva Pharmaceuticals USA

Completed

15 mg Mirtazapine Orally Disintegrating Tablets, Non-Fasting

Healthy

United States
Teva Pharmaceuticals USA

Completed

15 mg Mirtazapine Orally Disintegrating Tablets, Fasting

Healthy

United States
Pharmtechnology LLC

Recruiting

Bioequivalence Study of Perindopril /Amlodipine/Indapamide 8 mg (10 mg)/2.5 mg/10 mg Tablets in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
Parc de Salut Mar

Recruiting

Study of the Excretion of Orally Administered Corticosteroids for the Improval of the Detection of Said Substances in Anti-doping Controls (DACORSIN/4)

Healthy Volunteers

Spain
AbbVie (prior sponsor, Abbott)
Quintiles, Inc.

Completed

Study of Efficacy, Safety and Tolerability of Levodopa-Carbidopa Intestinal Gel in Levodopa-Responsive Parkinson's Subjects

Advanced Parkinson's Disease

United States, Germany
National Institute of Allergy and Infectious Diseases...

Completed

Topical Metronidazole and Miconazole Co-formulated Vaginal Suppositories for Preventing Vaginal Infections in HIV-seronegative Women

Candidiasis | Bacterial Vaginosis | Trichomoniasis

United States, Kenya
Alcon Research

Completed

A Bioequivalence Study of Tobradex AF

Cataract

United States
St. Jude Children's Research Hospital
Cookies for Kids' Cancer

Terminated

Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS)

United States
H. Lundbeck A/S

Completed

Efficacy of Vortioxetine Versus Escitalopram on Cognitive Function in Patients With Inadequate Response to Current Antidepressant Treatment of Major Depressive Disorder

Major Depressive Disorder

Finland, Germany, Serbia, Slovakia
Amgen

Completed

To Evaluate the Blockade of CGRP in Preventing PACAP-38 Induced Migraine-like Attacks With AMG 334 in Migraine Patients

Migraine

United States, Belgium, Netherlands
Massachusetts General Hospital
Dana-Farber Cancer Institute; Adienne SA

Withdrawn

Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplant (HSCT) For Lymphoma

Lymphoma

United States
Life Extension Foundation Inc.

Completed

Short Term Efficacy and Safety of Perispinal Administration of Etanercept in Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

United States
DSM Nutritional Products, Inc.

Completed

Dermal Irritation, Sensitization and Cumulative Irritation Potential of 6% Bemotrizinol

Sunburn

United States
Translational Oncology Research International

Completed

Dasatinib and Gemcitabine Hydrochloride or Gemcitabine Hydrochloride Alone in Treating Patients With Pancreatic Cancer Previously Treated With Surgery

Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer

United States
Eli Lilly and Company

Completed

Trial of Olanzapine in Patients With Manic or Mixed Episode of Bipolar I Disorder

Bipolar Disorder

Japan
Eli Lilly and Company

Completed

Efficacy Study of Early Onset of Antipsychotic Drug Action in Schizophrenia

Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorder

United States, Russian Federation, Argentina
Leiden University Medical Center
Dutch Diabetes Research Foundation

Completed

Metabolic Effects of Subchronic Dopamine D2 Receptor Blockade by Antipsychotic Drugs in Healthy Humans

Insulin Resistance | Dyslipidemia

Netherlands
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

A Study Evaluating Desvenlafaxine Sustained Release (DVS SR) in Adult Female Outpatients With Fibromyalgia

Fibromyalgia

United States
AstraZeneca

Completed

Anastrozole Biphosphonate Study in Postmenopausal Women With Hormone-Receptor-Positive Early Breast Cancer (SABRE)

Breast Cancer

United States, South Africa, Spain, France, Netherlands, United Kingdom, Greece, Canada
Bayer

Completed

Consumer Preference Study of Two Formulations of Phenylephrine Hydrochloride (Study CL2008-15)(P07530)(COMPLETED)

Seasonal Allergic Rhinitis | Vasomotor Rhinitis
Centre for Addiction and Mental Health

Recruiting

"Extended" (Alternate Day) Antipsychotic Dosing

Drug Therapy | Schizophrenia and Related Disorders | Antipsychotic Agents | Drug Administration Schedule

Canada
Jaime B Hyman

Completed

Olanzapine for Nausea After Surgery

Postoperative Nausea and Vomiting

United States
Hee Jun Kim
HK inno.N Corporation

Unknown

Proof-of-Concept Trial of Palonosetron and Olanzapine Without Dexamethasone for the Prevention of CIN

Chemotherapy-induced Nausea and Vomiting
VA Nebraska Western Iowa Health Care System
US Department of Veterans Affairs; Nebraska Educational Biomedical Research...

Terminated

Decision Aid to Facilitate Shared Decision Making During Treatment in Schizophrenia

Schizophrenia | Schizoaffective Disorder

United States
Bausch & Lomb Incorporated

Completed

Assessment of the Concentrations of Besifloxacin, Moxifloxacin, or Gatifloxacin in the Aqueous Humor of Subjects

Cataract Extraction

United States
Eli Lilly and Company

Completed

Safety Study of Olanzapine and a Comparator in Patients With Schizophrenia and Schizoaffective Disorder

Schizophrenia | Schizoaffective Disorder

United States
Eli Lilly and Company

Terminated

A Study in the Treatment of Acute Mania

Bipolar Disorder

Sweden
University of Arizona
Sidney R. Baer, Jr. Foundation

Recruiting

Proposal To Develop A Rapid And Cost-Effective Diagnostic Test For Schizophrenia

Schizophrenia

United States
Indivior Inc.

Completed

Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects

Hepatic Impairment | Hepatic Failure | Chronic Hepatitis C Infection With Hepatic Coma

United States
AstraZeneca

Withdrawn

BE Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin HCl XR Tablet Relative to a 5 mg Saxagliptin (Onglyza™) Tablet and a 500 mg Metformin HCl XR (Glifage® XR Marketed in Brazil by Merck S.A.) Tablet Co-Administered to Healthy Subjects in the Fasted and Fed States

Type 2 Diabetes

Brazil
Xiangya Hospital of Central South University

Completed

The Safety and Efficacy of the Enhanced Recovery After Surgery(ERAS)Applied on Cardiac Surgery With Cardiopulmonary Bypass (ERAS)

Valvular Heart Disease

China
University of Wasit

Active, not recruiting

Intra-articular Injections of Platelet-rich Plasma, Hyaluronic Acid, or Corticosteroids for Knee Osteoarthritis

Osteoarthritis, Knee

Iraq
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy, Plasma Exchange, and Immunotherapy (Pembrolizumab or Nivolumab) for the Treatment of Melanoma

Melanoma

United States
Nantes University Hospital

Completed

A Phase III Randomized, Blind, Double Dummy, Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery Occlusion (THEIA)

Central Retinal Artery Occlusion

France
National Cancer Institute (NCI)

Completed

Melphalan and Dexamethasone With or Without Bortezomib in Treating Patients With Previously Untreated Systemic Light-Chain Amyloidosis

Primary Systemic Amyloidosis | Light Chain Deposition Disease

United States
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; University of Bergen; Kamuzu... and other collaborators

Completed

Acceptability and Feasibility in the Context of the IMPROVE Trial in Kenya

Malaria in Pregnancy | Adherence, Treatment

Kenya
Rafic Farah, MD

Completed

Nonmyeloablative Hematopoietic Cell Transplantation (HCT) for Patients With Hematologic Malignancies Using Related, HLA-Haploidentical Donors: A Pilot Trial of Peripheral Blood Stem Cells (PBSC) as the Donor Source

Lymphoma | Leukemia | Myelofibrosis | MDS

United States
National Cancer Institute (NCI)

Recruiting

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Stage IV Renal Cell Cancer AJCC v8 | Sarcomatoid Renal Cell Carcinoma | Stage IV Bladder Cancer AJCC v8 | Stage IV Urethral Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Bladder Adenocarcinoma | Chromophobe Renal Cell Carcinoma | Papillary Renal Cell Carcinoma | Collecting Duct Carcinoma | Bladder... and other conditions

United States, Puerto Rico
Washington University School of Medicine
National Cancer Institute (NCI); National Institutes of Health (NIH); Atrium...

Completed

Comparative Effectiveness Multicenter Trial for Adhesion Characteristics of Ventral Hernia Repair Mesh

Ventral Hernia | Adhesions

United States
UNICANCER

Recruiting

Endocrine Therapy With Abemaciclib or Chemotherapy as Initial Metastatic Treatment in ER+/HER2- Breast Cancer (AMBRE)

Cancer Metastatic

France
Sanofi

Completed

Nasacort AQ Hypothalamic-Pituitary-Adrenal (HPA) Axis Study in Children With Allergic Rhinitis

Rhinitis, Allergic, Perennial and/or Seasonal

United States
Yonsei University
Chonbuk National University Hospital; Seoul St. Mary's Hospital; Kyungpook National... and other collaborators

Unknown

Efficacy and Safety of a Combination of Mycophenolate Mofetil and Corticosteroid in Advanced IgA Nephropathy (AIGA)

IgA Nephropathy

Korea, Republic of
National Cancer Institute (NCI)

Recruiting

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7

United States
National Cancer Institute (NCI)

Active, not recruiting

Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma

Metastatic Melanoma | Recurrent Melanoma | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC v8

United States
Sanofi
Regeneron Pharmaceuticals

Terminated

Effect of SAR153191 (REGN88) With Methotrexate in Patients With Active Rheumatoid Arthritis Who Failed TNF-α Blockers

Rheumatoid Arthritis

United States, Italy, Mexico, Colombia, Czechia, Spain
Yonsei University

Recruiting

Ticagrelor Monotherapy After 3 Months in the Patients Treated With New Generation Sirolimus Stent for Acute Coronary Syndrome (TICO Study)

Acute Coronary Syndrome

Korea, Republic of

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