Clinical Trials Sponsored by Onera BV

Total 355 results

University College, London
Stryker European Operations BV

Recruiting

Mako Functionally Aligned Total Knee Arthroplasty vs Mako Mechanically Aligned Total Knee Arthroplasty

Osteoarthritis | Osteo Arthritis Knee | Surgery

United Kingdom
Acerta Pharma BV
Merck Sharp & Dohme LLC

Active, not recruiting

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies (KEYNOTE145)

Multiple Myeloma | Hodgkin Lymphoma | Waldenström Macroglobulinemia | Burkitt Lymphoma | Small Lymphocytic Lymphoma (SLL) | Hairy Cell Leukemia | CLL | Mantle Cell Lymphoma (MCL) | Follicular Lymphoma (FL) | Richter's Syndrome | Indolent Non Hodgkin Lymphoma | Marginal Zone Lymphomas | Mediastinal Large B Cell...

United States
University College, London
Stryker EU Operations BV

Completed

Inflammatory Response Conventional Total Knee Replacement Versus Mako Total Knee Replacement

Arthritis | Knee Osteoarthritis | Surgery

United Kingdom
Khondrion BV
Drug Research Unit Ghent, Belgium

Completed

A Dose-escalating Clinical Trial With KH176

Mitochondrial Disease | MELAS | Leigh Syndrome | LHON | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation

Belgium
SMART Clinical Products BV
Ziekenhuis Oost-Limburg

Completed

Evaluation of the iD-SystemTM, One-Handed Disposable Internal Defibrillation System. (iD-System)

Ventricular Fibrillation | Ventricular Tachycardia

Belgium
Enceladus Pharmaceuticals BV
University Hospital, Aachen; Accelovance

Terminated

A Evaluation of the Safety of Oncocort IV Pegylated Liposomal Dexamethasone Phosphate in Patients With Progressive Multiple Myeloma (AMETHYST)

Multiple Myeloma
Wageningen University and Research
Asahimatsu Support BV

Completed

Kori-tofu Proteins and Blood Glucose Response (KoPro)

Glucose Intolerance

Netherlands
ECRI bv
GE Healthcare; Amgen; HeartFlow, Inc.

Withdrawn

Multislice Computed Tomography Assessment of PCSK9 Inhibition on Coronary Perfusion (MARKOV)

Coronary Artery Disease
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

Pembrolizumab Alone and In Combination With Acalabrutinib (ACP-196) in Subjects With Advanced Non-small Cell Lung Cancer (KEYNOTE166)

Carcinoma, Non-Small-Cell Lung

United States
Janssen Research & Development, LLC
Janssen Biologics BV

Completed

A Long Term Safety Study of Infliximab (Remicade) in in Ulcerative Colitis Patients

Ulcerative Colitis

United States, France, United Kingdom, Belgium, Switzerland, Israel, Canada, Australia, Netherlands, New Zealand, Austria, Germany, Denmark, Czechia, Argentina
Sahajanand Medical Technologies Pvt. Ltd.
Cardialysis BV

Terminated

SERIES III RUN-IN Clinical Trial: A Comparison of the Supralimus® Stent With the Xience V™ Stent

Coronary Artery Disease

India, Brazil, Saudi Arabia
Maastricht University Medical Center
Biomet Nederland BV

Unknown

Is the Use of Blood Platelets Effective in the Treatment of Difficult Fistulas Related to the Anal Sphincter?

Rectal Fistula

Netherlands
Italfarmaco
Opera CRO, a TIGERMED Group Company

Completed

Clinical Trial Study To Evaluate The Performance And Safety Of Ainara®

Vaginal Disease

Romania
Khondrion BV
Julius Clinical; ProPharma Group; Certara

Completed

The KHENEREXT Study

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) | Chronic Progressive External Ophthalmoplegia (CPEO)

Netherlands, Denmark, United Kingdom, Germany
ECRI bv
Boston Scientific Corporation; Philips Healthcare

Active, not recruiting

The OPTIMAL Randomized Controlled Trial (OPTIMAL)

Left Main Coronary Artery Stenosis

Spain, United Kingdom, Italy
Atlantia Food Clinical Trials
Caelus Pharmaceuticals BV

Completed

Efficacy and Safety of 12-weeks Supplementation of Eubacterium Hallii on Insulin Sensitivity and Glycaemic Control

Glucose Metabolism Disorders | Metabolic Syndrome | Insulin Resistance | Impaired Glucose Tolerance | Insulin Sensitivity | Pre Diabetes

Ireland, United States, United Kingdom
ECRI bv
Sahajanand Medical Technologies Pvt. Ltd.

Completed

Thin Strut Sirolimus-eluting Stent in All Comers Population vs Everolimus-eluting Stent (TALENT)

Coronary Stenosis

Bulgaria, Hungary, Italy, Netherlands, Poland, Spain, United Kingdom
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

Study of the Combination of Acalabrutinib (ACP-196) and Pembrolizumab in Advanced Head and Neck Squamous Cell Carcinoma (KEYNOTE147)

Squamous Cell Carcinoma of the Head and Neck

United States
Acerta Pharma BV
Merck Sharp & Dohme LLC

Completed

Study of the Combination of ACP-196 and Pembrolizumab in Subjects With Platinum Resistant Urothelial Bladder Cancer (KEYNOTE143)

Metastatic Urothelial Carcinoma

United States
University of Pittsburgh
MucoVax, BV, the Netherlands

Terminated

Whey Protein Concentrate 40% Made of Milk of Immunized Cows to Aid in the Prevention of Relapse of Clostridium Difficile-Diarrhea

Positive C-Diff Culture

United States
Vissum, Instituto Oftalmológico de Alicante
AkkoLens Clinical bv

Completed

Efficacy of the AkkoLens IOL in Patients With Cataract

Cataract
Cardiovascular Research Foundation, New York
Cardialysis BV; Avania

Active, not recruiting

Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD)

Aortic Valve Stenosis

United States, Canada, Netherlands
ECRI bv
Terumo Europe N.V.; Abbott Medical Devices

Completed

ABSORB STEMI: the TROFI II Study

Acute ST Segment Elevation Myocardial Infarction

Denmark, Netherlands, Spain, Switzerland
Maastricht University Medical Center
Winclove Bio Industries BV

Completed

The Effect of a Multispecies Probiotic on Hypersensitivity in Irritable Bowel Syndrome (IBS) Patients

Hypersensitivity | Irritable Bowel Syndrome

Netherlands
Maastricht University Medical Center
Stryker European Operations BV

Completed

RCT Comparing the DEXA Results of the HA-Omnifit Versus the Symax Uncemented Hip Stem

Patients With Osteoarthritis of the Hip Joint Elligable for a Uncemented Hipprosthesis
Italfarmaco
Opera CRO, a TIGERMED Group Company

Completed

Open Non-Comparative Study To Evaluate Administration Of a New Nutraceutical

Sleep Disorder

Romania
Italfarmaco
Opera CRO, a TIGERMED Group Company

Completed

Open Non-Comparative Clinical Trial Study To Evaluate The Performance And Safety Of Ainara®

Vaginal Disease

Romania
Brigham and Women's Hospital
The OPERA Investigators

Completed

Omega-3 Fatty Acids for Prevention of Post-Operative Atrial Fibrillation (OPERA)

Atrial Fibrillation

United States
Gokalp Oner

Recruiting

The Effects of Miminal Stimulation Protocol on Preimplantation Genetic Screening

Preimplantation Genetic Screening

Turkey
University Medical Center Groningen
Netherlands Heart Foundation; Disphar International B.V.; Teva Nederland BV; Tiofarma... and other collaborators

Active, not recruiting

Digoxin Evaluation in Chronic Heart Failure: Investigational Study In Outpatients in the Netherlands (DECISION)

Heart Failure

Netherlands
LiteVax BV
University Hospital, Ghent; HarmonyCR, Melle, Belgium

Recruiting

Safety, Tolerability, Immunogenicity and Immunological Mechanisms of TETRALITE, a Novel Seasonal Influenza Vaccine (TETRALITE-Ib)

Vaccination Reaction

Belgium
ECRI bv
Siemens Healthineers AG; Pie Medical Imaging

Recruiting

Fractional Flow Reserve or 3D-Quantitative-Coronary-Angiography Based Vessel-FFR Guided Revascularization (FAST III)

Coronary Artery Disease

Germany, Ireland, Italy, Netherlands, Spain, United Kingdom, France
Acerta Pharma BV
National Institutes of Health (NIH)

Active, not recruiting

Acalabrutinib in Patients With Relapsed/Refractory and Treatment naïve Deletion 17p CLL/SLL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Washington University School of Medicine
Acerta Pharma BV

Active, not recruiting

Acalabrutinib With Bendamustine / Rituximab Followed by Cytarabine / Rituximab for Untreated Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
GSO Global Clinical Research BV
Karyopharm Therapeutics Inc

Terminated

Phase 1 Trial To Evaluate mFOLFOX6 With Selinexor In Patients With Metastatic Colorectal Cancer (SENTINEL)

Colorectal Neoplasm

Germany, Belgium
GSO Global Clinical Research BV
Karyopharm Therapeutics Inc

Completed

A Phase II Study of Selinexor Plus Cytarabine and Idarubicin in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia (Relapsed/Refractory)

Germany
Newtricious R&D BV
Sprim Advanced Life Sciences

Completed

Intervention Trial in Early Age-related Macular Degeneration (I-TEAM)

Age-related Macular Degeneration (AMD)

United States, Germany, Netherlands, United Kingdom
Abbott
Quintiles, Inc.; Synexus; author! et al. BV

Completed

Comparison of the Effect of Eprosartan and Eprosartan Mesylate on Blood Pressure in Essential Hypertension

Essential Hypertension

Germany, Russian Federation, United Kingdom
Giellepi S.p.A
Opera CRO, a TIGERMED Group Company

Not yet recruiting

Randomised, Double-blind, Placebo-controlled to Assess the Efficacy and Safety of the Food Supplement Microsmin® Plus

Haemorrhoids

Romania
SIFI SpA
Opera CRO, a TIGERMED Group Company

Completed

The Visual Performances of a Progressive Multifocal Intraocular Lens With Extended Depth of Focus

Cataract | Presbyopia

Italy
SIFI SpA
Opera CRO, a TIGERMED Group Company

Terminated

Non-Inferiority Study Comparing MINI WELL READY® and FineVision® in Patients With Cataract Surgery

Cataract | Presbyopia

France
MDM S.p.A.
Opera CRO, a TIGERMED Group Company

Completed

Non-Comparative Study to Assess the Efficacy and Safety of the New Food Supplement FaseMETS

Metabolic Syndrome

Romania
Citieffe S.r.l
Opera CRO, a TIGERMED Group Company

Unknown

Observational Retrospective and Prospective Study on the Treatment of Femoral Fractures With EBA2

Femoral Fractures

Italy
ECRI bv
AstraZeneca; The Medicines Company; Biosensors International

Completed

GLOBAL LEADERS: A Clinical Study Comparing Two Forms of Anti-platelet Therapy After Stent Implantation

Coronary Artery Disease (CAD)

Australia, Austria, Belgium, Brazil, Bulgaria, Canada, Denmark, France, Germany, Hungary, Italy, Netherlands, Poland, Portugal, Singapore, Spain, Switzerland, United Kingdom
Maastricht University Medical Center
Stryker European Operations BV

Unknown

RSA Study Using Two Types of Uncemented Acetabular Components and the Uncemented HA Coated Symax Stem (RSA)

Osteoarthritis

Netherlands
Martini Hospital Groningen
Baxter Healthcare Corporation; Roche BV Netherlands

Terminated

Peritoneal Dialysis in Congestive Heart Failure (PDinCHF)

Congestive Heart Failure

Netherlands
Effik SA
Opera CRO, a TIGERMED Group Company

Not yet recruiting

Prevalence and Burden of Nausea and Vomiting in Pregnant Women in Switzerland: Survey Purity 2022

Nausea | Vomiting of Pregnancy
BMG Pharma
Opera CRO, a TIGERMED Group Company

Completed

Evaluation of Safety and Performance of Ialuxid Gel in Treatment of Acne Vulgaris, Impetigo and Folliculitis

Acne Vulgaris | Folliculitis | Impetigo

Romania
Biokosmes Srl
Opera CRO, a TIGERMED Group Company

Completed

Open-label Trial Evaluating Four Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste, and Mouthwash

Oral Hygiene | Dental Plaque | Toothbrushing

Italy
Giellepi S.p.A
Opera CRO, a TIGERMED Group Company

Completed

Clinical Trial to Assess the Efficacy of µSmin® Plus

Chronic Venous Disease

Romania

Clinical Trials Sponsored by Onera BV

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