Search clinical trials for: First in Man

Total 469222 results

Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)

Limited-stage Small Cell Lung Cancer (LS-SCLC)

China, France, United States, Spain, Taiwan, Korea, Republic of, Turkey, Italy, Netherlands, Georgia, Germany, Belgium, Poland, Romania
Boston Scientific Corporation

Recruiting

Pulsed Field Ablation (PFA) Versus Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation (AVANT GUARD)

Persistent Atrial Fibrillation

United States, Canada, Australia, Singapore, Spain, Croatia, Germany, Italy, Belgium
PharmaMar

Recruiting

Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo)

Leiomyosarcoma

United States, Spain, United Kingdom, France, Germany, Italy, Belgium, Austria
First Affiliated Hospital of Zhejiang University

Recruiting

Micro-expressions in Patients With Prolonged Disorders of Consciousness

Consciousness Disorders

China
Mingzhao Xiao

Recruiting

Contrast-enhanced CT-based Deep Learning Model for Preoperative Prediction of Disease-free Survival (DFS) in Localized Clear Cell Renal Cell Carcinoma (ccRCC)

Clear Cell Renal Cell Carcinoma | Recurrent Renal Cell Cancer | Prognostic Cancer Model

China
Peking University First Hospital

Not yet recruiting

Different Dose Esketamine and Dexmedetomidine for Supplemental Analgesia and Longterm Outcomes

Dexmedetomidine | Chronic Postsurgical Pain | Postoperative Analgesia | Esketamine | Scoliosis Correction

China
Amasya University
Ataturk University

Not yet recruiting

The Effect of Birth Ball and Birth Dance Applied in the First Stage of Labor on Some Parameters

Satisfaction, Patient | Pain, Labor
First Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

Efficacy and Safety of Urinary Kallidinogenase in the Treatment of Acute Ischemic Stroke Combined With Type 2 Diabetes Mellitus (TK-SEEK)

Type 2 Diabetes | Acute Ischemic Stroke

China
Hoffmann-La Roche

Recruiting

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma (GLOBRYTE)

Lymphoma

Korea, Republic of, United States, Spain, France, Brazil, China, Canada, Australia, Sweden, Taiwan, Italy, United Kingdom
Zhejiang University

Recruiting

Efficacy and Safety of Intravenous YOLT-201 for Transthyretin Amyloidosis Cardiomyopathy

Transthyroxin Amyloidosis Cardiomyopathy

China
Beijing Chest Hospital
National Medical Center for Infectious Diseases

Recruiting

Innovating Shorter, All- Oral, Precised, Individualized Treatment Regimen for Rifampicin Resistant Tuberculosis：Contezolid, Delamanid and Bedaquiline Cohort (INSPIRE-CODA)

Pulmonary Tuberculosis | Rifampicin-resistant Tuberculosis

China
Jiangsu Alphamab Biopharmaceuticals Co., Ltd

Not yet recruiting

JSKN003 Versus Treatment Of Physician'S Choice For HER2-low, Unresectable and/or Metastatic Breast Cancer Subjects

Breast Cancer

China
FX Shoulder Solutions

Recruiting

FX Shoulder Prospective Clinical Study

Osteoarthritis Shoulder | Rotator Cuff Syndrome of Shoulder and Allied Disorders | Fracture, Shoulder

United States
Anhui Medical University

Recruiting

Intervention Effect of Transcranial Alternating Current Stimulation (tACS) on Disorder of Consciousness (DOC)

Disorders of Consciousness

China
Boehringer Ingelheim

Recruiting

A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)

Obesity

United States, Korea, Republic of, Belgium, Australia, United Kingdom, Italy, Mexico, Spain, Germany, Taiwan, Netherlands, Brazil, Hungary, Denmark, Canada, Austria, China, Poland, Finland, Greece, Hong Kong, Czechia, Portugal, Saudi... and more
Guizhou Provincial People's Hospital

Recruiting

the Difference of Follow-up Methods of Neonatal Jaundice (NJFU)

Neonatal Jaundice

China
Pfizer

Recruiting

A 104-Week Study of Ritlecitinib Oral Capsules in Adults With Nonsegmental Vitiligo (Active and Stable) Tranquillo 2 (Tranquillo 2)

Stable Nonsegmental Vitiligo | Active Nonsegmental Vitiligo

China, Spain, Taiwan, Japan, Canada, United States, Hungary, Poland, Slovakia, Germany, Bulgaria
Mclean Hospital
National Institute of Mental Health (NIMH); Massachusetts General Hospital; Boston... and other collaborators

Recruiting

Enhanced Coordinated Specialty Care for Early Psychosis

Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Psychosis | Psychosis Nos/Other

United States
Sanofi

Recruiting

A Study to Evaluate Efficacy and Safety of SAR441566 in Adults With Plaque Psoriasis (SPECIFI-PSO)

Psoriasis

Chile, Germany, Mauritius, Japan, Canada, United States, Georgia, Turkey, Spain, Czechia, Hungary, Poland, Portugal, United Kingdom, China, Argentina
Bristol-Myers Squibb

Recruiting

A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer

Metastatic Castration-resistant Prostate Cancer

United States
The Third Affiliated hospital of Zhejiang Chinese...
Zhejiang University; The First Affiliated Hospital of Zhejiang Chinese Medical...

Not yet recruiting

Two Electroacupuncture Waveforms for Different Severity Groups of Bell Palsy

Bell Palsy

China
GlaxoSmithKline
iTeos Therapeutics

Recruiting

Phase 2 Platform Study of Novel Immunotherapy Combinations as First-Line Treatment in Participants With PD-L1 Positive Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Neoplasms, Head and Neck

United States, Italy, Spain, Taiwan, Germany, Greece, Korea, Republic of, Romania, Sweden, Turkey, Canada, Argentina, Finland, Brazil, Japan, Poland, Portugal, France, Denmark, Hungary, Norway
Hangzhou Endonom Medtech Co., Ltd.

Recruiting

Guo's False Lumen Embolization : The First in Man Study of WeFlow-EndoSeal Aorta Vascular Plug System

Aortic Dissection Aneurysm

China
I.M. Sechenov First Moscow State Medical University

Recruiting

Non-contrast Magnetic Resonance Angiography in Deep Inferior Epigastric Perforator Flap Breast Reconstruction Planning

Breast Cancer | Postsurgical Acquired Absence of Organ

Russian Federation
First Affiliated Hospital of Zhejiang University

Recruiting

Augmentation of Interpersonal Psychotherapy With High-Definition Transcranial Direct Current Stimulation for Adolescent Depression

Depressive Disorder

China
First Affiliated Hospital Bengbu Medical College

Recruiting

Safety and Efficacy Study of NGGT002 in PKU Adult Subjects

Phenylketonurias

China
Zhejiang Chinese Medical University
The First Affiliated Hospital of Zhejiang Chinese Medical University; The Second...

Not yet recruiting

Effectiveness of Electroacupuncture in the Treatment of Diabetic Peripheral Neuropathy

Diabetic Peripheral Neuropathic Pain

China
Nanjing First Hospital, Nanjing Medical University

Recruiting

Study of 177Lu-PSMA-0057 in Metastatic Prostate Cancer

Metastatic Prostate Cancer

China
Centre Hospitalier Universitaire de Nīmes

Recruiting

Impact of an Echographic Algorithm on Hemodynamic Optimization in the First 4 Days of Septic Shock Management (STOPFLUID)

Shock, Septic | Hemodynamic Instability

France
Eli Lilly and Company

Recruiting

A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States, Australia, Canada, Germany, Greece, Poland
Celgene
Bristol-Myers Squibb

Recruiting

A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation (KarMMa-9)

Multiple Myeloma

Austria, Denmark, United States, Spain, Australia, Japan, France, Korea, Republic of, Israel, Italy, Canada, Greece, Belgium, Norway, Romania, United Kingdom, Czechia, Germany, Poland
Eli Lilly and Company

Recruiting

A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With Metformin (ACHIEVE-3)

Type 2 Diabetes

United States, China, Japan, Argentina, Puerto Rico, Mexico
First Affiliated Hospital of Zhejiang University

Recruiting

Positron Emission Tomography in Transcranial Magnetic Stimulation Intervention for Treatment-resistant Depression

Treatment Resistant Depression | Visual Perceptual Weakness

China
Janssen Research & Development, LLC

Recruiting

Study of Guselkumab Versus Placebo for the Treatment of Low Body Surface Area Moderate Plaque Psoriasis (SPECTREM)

Moderate Plaque Psoriasis

United States, Canada
Cellular Sciences, inc.
Family First Medical Research Center

Recruiting

The Effect of N115 on Coughing in IPF Patients

Idiopathic Pulmonary Fibrosis

United States
First Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

Multimodal Recurrence Scoring System for Stratifying Stage III Clear Cell Renal Cell Carcinoma of Receiving Adjuvant Treatment

Renal Cell Carcinoma
Dr Cipto Mangunkusumo General Hospital

Recruiting

The 1000 First Day of Life : Effect of Multi Micronutrients Supplementation on Pregnancy Outcomes

Maternal-Fetal Relations | Nutrition, Healthy | Nutritional Deficiency | Maternal Care Patterns | Perinatal Outcome | Maternal Outcome

Indonesia
Peking University First Hospital
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical... and other collaborators

Recruiting

A Phase II Neoadjuvant Study of Darolutamide Plus ADT in Men With Localized Prostate Cancer

Prostate Cancer

China
Sanofi
Kymera Therapeutics, Inc.

Recruiting

A Phase 2 Study to Evaluate the Efficacy and Safety of SAR444656 Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa (ZEN)

Hidradenitis Suppurativa

Spain, United States, Germany, Greece, Poland
Shandong First Medical University
Jinan Central Hospital

Recruiting

MRD Application in Colorectal Cancer Patients

Colorectal Cancer | Surgery | Chemotherapy Effect

China
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Progressive Pulmonary Fibrosis

Progressive Pulmonary Fibrosis

China, United States, Taiwan, Japan, Korea, Republic of, Hungary, Canada, Argentina, Australia, Austria, Belgium, Brazil, Chile, Colombia, Denmark, Finland, France, Germany, Greece, India, Ireland, Italy, Mexico, Peru, Poland, Portugal, Spain, Switzerla... and more
ExoRNA Bioscience

Recruiting

The Safety and Tolerability Study With ER2001 Intravenous Injection in Adults With Early Manifest Huntington's Disease

Huntington Disease

China
Erasmus Medical Center

Recruiting

Safely Reduce Cystoscopic Evaluations for Hematuria Patients (SeARCH)

Bladder Cancer | Urothelial Carcinoma | Hematuria | Urothelial Neoplasm

Netherlands
Min Su

Not yet recruiting

The Effect of Preoperative Prone Position Training on PPCs in Patients Undergoing Laparoscopic Sleeve Gastrectomy

Postoperative Pulmonary Complications

China
Guangdong Second Provincial General Hospital

Recruiting

Comparative Effects of Ciprofol and Propofol on Pain Intensity on the First Day After Surgery: a Retrospective, Propensity Score Matched, Cohort Study

Acute Pain | Anesthesia | Risk Reduction

China
First Affiliated Hospital of Zhejiang University

Recruiting

Impacts of Different ART Regimens on Lipid Metabolism in People Living With HIV (ART)

HIV Infection | Combined Antiretroviral Therapy

China
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Effects of Early and Late Time-restricted Eating on Overweight Adults With Metabolic Syndrome

Metabolic Syndrome | Overweight and Obesity | Time Restricted Eating
Xgene Pharmaceutical Group

Recruiting

XG005 for Pain Control in Subjects Undergoing Bunionectomy

Acute Pain

United States
Samsung Medical Center

Not yet recruiting

An Open Label Phase II Study of First-Line Maintenance Enzalutamide Following Docetaxel Plus Androgen-Deprivation Therapy in Patients With Previously-Untreated, Metastatic, Castration-Naive Prostatic Adenocarcinoma

Prostatic Adenocarcinoma

Korea, Republic of
Hospices Civils de Lyon

Not yet recruiting

Prevention of Vasovagal Reactions in First-time Blood Donors Using a Combined PSYchological and Physiological Approach (PREDONPSY)

Vasovagal Reaction

France

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