Clinical Trials Sponsored by AGO Research GmbH

Total 740 results

AIO-Studien-gGmbH
Merck Sharp & Dohme LLC

Terminated

Study of Pembrolizumab Maintenance Following First-Line Platinum Based Chemotherapy in Patients With Metastatic Squamous - Non-Small Cell Lung Cancer (sNSCLC) (PRIMUS)

Metastatic Squamous Non-small Cell Lung Cancer

Germany
Johannes Gutenberg University Mainz
AIO-Studien-gGmbH

Completed

Efficacy of Cetuximab in Combination With Irinotecan and 5- FU/FA in Treatment of Metastatic Gastric Cancer (GC-CIF-2005)

Adenocarcinoma of Stomach or Esophagogastric Junction

Germany
AIO-Studien-gGmbH
Merck Sharp & Dohme LLC

Completed

Neoadjuvant Anti PD-1 Immunotherapy in Resectable Non-small Cell Lung Cancer (NEOMUN)

Non-small Cell Lung Cancer (NSCLC)

Germany
Palleos Healthcare GmbH
Roche Pharma AG; Cankado GmbH; WSG WOMEN´S HEALTHCARE STUDY GROUP

Completed

Study to Compare Neoadjuvant Combination of Trastuzumab and Pertuzumab With Concurrent Taxane Chemotherapy or Endocrine Therapy and Quality of Life Assessment Under Adjuvant Therapy in Operable HER2+/HR+ Breast Cancer Patients (TP-II)

Breast Neoplasms

Germany
TME Pharma AG
Profil Institut für Stoffwechselforschung GmbH

Completed

NOX-E36 Multiple Ascending Dose Study in Healthy Volunteers and Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Germany
pfm medical ag
MDT Medical Device Testing GmbH

Completed

Procedural Success and Safety of the Nit-Occlud® Patent Foramen Ovale (PFO) Closure Device and Its Application System (09k003)

Heart Septal Defects, Atrial | Foramen Ovale, Patent | Heart Catheterization

Germany
Aesculap AG
Raylytic GmbH; B. Braun Medical France

Recruiting

Evaluation of Medium Cross-linked Polyethylene With and Without Vitamin E for Total Knee Arthroplasty (VIKEP)

Arthritis, Rheumatoid | Osteoarthritis, Knee | Joint Instability | Intra-Articular Fractures | Genu Valgum or Varum

France, Germany
Joanneum Research Forschungsgesellschaft mbH

Completed

An Exploratory Study in Healthy Volunteers to Identify Factors Influencing Bioequivalence Studies on Moderately Lipophilic Drugs Using Dermal Open Flow Microperfusion (dOFM)

Healthy | Dermal Pharmacokinetic Measurements

Austria
Fresenius Medical Care Deutschland GmbH
Winicker Norimed GmbH; James Motta, Clinical Research Associate (CRA)

Completed

Comparison of Efficacy and Tolerability of APD Treatment With Different PD Cyclers

Renal Failure | End Stage Renal Disease

Chile
Joanneum Research Forschungsgesellschaft mbH

Completed

An Exploratory Study in Healthy Volunteers to Investigate the Cross-talk Between Local Drug Concentrations in the Skin and Systemic Concentrations During Topical Bioequivalence Studies Using Dermal Sampling Techniques

Healthy | Dermal Pharmacokinetic Measurement

Austria
Joanneum Research Forschungsgesellschaft mbH

Completed

Evaluate the Ability of dOFM for BE Testing of Topically Applied Diclofenac Sodium Products in Healthy Subjects

Healthy

Austria
Joanneum Research Forschungsgesellschaft mbH

Completed

An Exploratory Pilot Study in Healthy Volunteers to Assess the Parameters for the Design of Bioequivalence Studies on Moderately Lipophilic, Moderately to Highly Protein Bound Drugs Using Dermal Open Flow Microperfusion (dOFM)

Dermal Pharmacokinetic Measurements | Dermatology/Skin - Other

Austria
University Hospital Tuebingen
FGK Clinical Research GmbH; VisMederi srl; Staburo GmbH; Viedoc Technologies AB

Recruiting

A Study to Assess the Safety and Immunogenicity of a COVID-19 Vaccine Booster in Healthy Adults

COVID-19

Germany
Lohmann & Rauscher
CRI-The Clinical Research Institute GmbH

Not yet recruiting

Suprasorb® CNPendo Used for Negative Pressure Therapy in the Oesophagus and Rectum to Support Defect and Wound Healing (Velox)

Esophagus Injury | Rectal Lesion

Germany
Clinical Research Center Kiel GmbH
University of Kiel

Completed

Study on the Predictive Value of the Natural Calcium Isotope Ratio in Urine and Serum for the Diagnosis of Osteoporosis

Osteoporosis

Germany
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

A Study to Evaluate Tapentadol (CG5503) in the Treatment of Chronic Tumor-Related Pain Compared With Placebo and Morphine

Pain | Tumor

Austria, Bulgaria, Croatia, Czechia, France, Germany, Hungary, Italy, Moldova, Republic of, Poland, Romania, Russian Federation, Serbia, Slovakia, Spain, Sweden
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

A Study to Evaluate the Efficacy and Safety of CG5503 Prolonged Release (PR) in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee

Pain | Knee Osteoarthritis

Austria, Croatia, Germany, Hungary, Italy, Latvia, Netherlands, Poland, Portugal, Romania, Slovakia, Spain, United Kingdom
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

Drug-drug Interaction Study to Evaluate the Effect of Omeprazole on CG5503 (Tapentadol)

Pharmacokinetic

Belgium
Clinical Research Center Kiel GmbH
European Commission; BioActor

Completed

DBRCT on the Effect of Wheat Polysaccharides on Common Cold Infections in Elderly (Fib-CC-2014)

Common Cold | Upper Respiratory Infections

Germany
Pro Bono Bio
International Medical Research - Partner GmbH

Unknown

Study of FLEXISEQ® for Treatment of Osteoarthritis of the Knee in NSAID-compromised Patients (OANIT)

Osteoarthritis

Germany
Almirall, S.A.
Harrison Clinical Research; Almirall Hermal GmbH

Completed

LAS41008 in Moderate to Severe Chronic Plaque Psoriasis

Plaque Psoriasis

Austria, Germany, Netherlands, Poland
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain From Bunionectomy.

Pain | Arthralgia | Bunion | Hallux Valgus

United States
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Terminated

A Long-term Safety Study With Tapentadol ER and Oxycodone CR in Patients With Moderate to Severe Pain Due to Chronic, Painful Diabetic Peripheral Neuropathy (DPN)

Diabetic Neuropathy, Painful | Diabetic Polyneuropathy

United States
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of Tapentadol ER Compared With Placebo in Patients With Chronic, Painful Diabetic Peripheral Neuropathy

Diabetic Peripheral Neuropathy

United States, Canada, Puerto Rico
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Safety and Efficacy Study for Tapentadol (CG5503) Extended Release for Patients With Painful Diabetic Peripheral Neuropathy

Diabetic Neuropathy
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

Tapentadol (CG5503)

Pain | Osteoarthritis, Knee
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Study to Evaluate the Effectiveness and Safety of Multiple Doses of Tapentadol(CG5503) in Patients Awaiting Joint Replacement Surgery

Osteoarthritis | Arthralgia | Pain Assessment
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Study to Evaluate 90-Day Safety of Tapentadol(CG5503) Immediate Release (IR) or Oxycodone Immediate Release in Patients With Chronic Pain

Osteoarthritis | Arthralgia | Low Back Pain | Sciatica | Pain Intensity Assessment
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

Efficacy and Safety of Tapentadol Extended Release Tablets in the Treatment of Moderate to Severe Pain in Subjects With Knee Osteoarthritis

Chronic Pain | Knee Pain | Osteoarthitis
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Randomized, Double-Blind, Parallel-Arm, Placebo and Active Controlled Dose-Ranging Study of the Efficacy and Safety of Multiple Doses of Tapentadol IR for Postoperative Pain Following Bunionectomy Surgery

Pain | Postoperative Pain
University of Vienna
CRI Collagen Research Institute GmbH

Completed

Influence of Specific Collagen Peptides on Recovery After Exercise Induced Muscle Damage

Recovery

Austria
ReAlta Life Sciences, Inc.
FGK Clinical Research GmbH

Completed

A Clinical Study to Determine the Safety, Tolerability and Effect of RLS-0071 Doses When Given to Healthy Adults After Inhaling LPS

Healthy

Germany
Becton, Dickinson and Company
FGK Clinical Research GmbH

Completed

Prospective Observational Study of the Power PICC Family of Devices and Accessories

Peripherally Inserted Central Catheter

Germany, Czechia, Austria, Belgium, Denmark, Italy, Netherlands, Spain, Switzerland
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Terminated

A Study to Evaluate the Effectiveness and Safety of CG5503 (Tapentadol) in the Treatment of Chronic Tumor Related Pain Compared With Placebo and Morphine

Pain | Cancer | Neoplasm

United States, Argentina, Chile, France, Latvia, Ukraine
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

A Study to Evaluate the Efficacy and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain After Abdominal Hysterectomy

Hysterectomy | Postoperative

Russian Federation, Hungary, Latvia, Poland, Romania, Serbia, Slovakia, Slovenia, Ukraine
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

Study on the Safety and Effectiveness of Switching Between Two Forms of Tapentadol in Patients With Chronic Low Back Pain

Low Back Pain
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

An Open-label Extension Study With Flexible Dosing of Extended-release (ER) Tapentadol (CG5503) to Treat Patients With Moderate to Severe Chronic Pain

Pain | Osteoarthritis | Low Back Pain

United States, Australia, Canada, New Zealand
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Study to Evaluate Long-Term Safety of Multiple Doses of Tapentadol (CG5503) Prolonged-Release (PR) and Oxycodone Controlled-Release (CR) in Patients With Chronic Pain

Pain | Lower Back Pain | Osteoarthritis, Knee | Osteoarthritis, Hip

United States, Canada
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Terminated

A Study to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) in the Treatment of Acute Pain After Hip Replacement Surgery Compared With Oxycodone and Placebo Followed by a Voluntary Open-Label Extension For Safety

Arthroplasty

United States, United Kingdom, Belgium, Spain, Canada, Finland, New Zealand, Sweden
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Study to Compare the Frequency of Constipation Symptoms With Tapentadol Immediate Release (IR) Treatment Versus Oxycodone IR Treatment in Patients With End-stage Joint Disease

Arthritis | Joint Diseases | Osteoarthritis
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

A Trial to Evaluate CG5503 Efficacy and Safety in Acute Pain After Bunionectomy

Pain | Postoperative Pain | Acute Pain | Bunionectomy

United States
Stryker Trauma GmbH
Global Research Solutions; Stryker Osteosynthesis

Completed

Re-Evaluation of GAmma3 Intramedullary Nails in Hip Fracture (REGAIN) (REGAIN)

Femoral Neck Fractures | Intertrochanteric Fracture

Sweden, Denmark, Canada
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Study to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) in the Treatment of Acute Pain From Bunionectomy Compared With Placebo Followed by a Voluntary Open Label Extension for Safety.

Arthralgia | Bunion | Hallux Valgus | Pain Assessment | Tapentadol
Sciotec Diagnostic Technologies GmbH
Austrian Research Promotion Agency

Completed

Efficacy of Fructose Metabolizing Enzymatic Product in Fructose Malabsorption

Fructose Malabsorption

Austria
keepMED Ltd.
CRI-The Clinical Research Institute GmbH

Not yet recruiting

Efficacy and Safety of keepMED Positive Airway Pressure Device in Patients With Obstructive Sleep Apnea (keePaOSA)

Obstructive Sleep Apnea
Humacyte, Inc.
FGK Clinical Research GmbH; Aptiv Solutions

Completed

Safety and Efficacy of a Vascular Prosthesis for Hemodialysis Access in Patients With End-Stage Renal Disease

Kidney Failure, Chronic | End-stage Renal Disease

United States
University Hospital, Bonn
Mundipharma Research GmbH & Co KG

Terminated

A Clinical Trial to Assess the Safety & Efficacy of the Treatment of Patients With Metastasis From Malignant Melanoma - Treatment Consists of the Substances Lomustine (Capsules) & Cytarabine (Injected Into an Area Near the Spinal Cord), Accompanied by Radiotherapy of the Brain

Leptomeningeal Metastasis From Malignant Melanoma

Germany
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) Extended Release (ER) in Patients With Moderate to Severe Chronic Low Back Pain

Low Back Pain
University Hospital Tuebingen
German Research Foundation; CenTrial GmbH

Completed

Safety and Effectiveness of Repetitive Transcranial Magnetic Stimulation in the Treatment of Tinnitus

Tinnitus

Germany
Palleos Healthcare GmbH
Roche Pharma AG; University Hospital, Essen; University Hospital Erlangen; Phaon...

Active, not recruiting

Study to Compare a Mono Atezolizumab Window Followed by a Atezolizumab - CTX Therapy With Atezolizumab - CTX Therapy (neoMono)

Triple-negative Breast Cancer

Germany

Clinical Trials Sponsored by AGO Research GmbH

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