Clinical Trials Sponsored by Liggins Institute

Total 74412 results

National Cancer Institute (NCI)

Recruiting

A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy

Thymic Carcinoma | Thymoma

United States
National Cancer Institute (NCI)

Recruiting

Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

Stomach Neoplasms | Stomach Cancer | Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS) | Hereditary Diffuse Gastric Cancer (HDGC) | Familial Diffuse Gastric Cancer

United States
National Cancer Institute (NCI)

Recruiting

Long-Term Follow-up of People Undergoing Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Tissue Donors

United States
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Medtronic

Recruiting

In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps

Sinusitis | Nasal Polyps

Canada
National Eye Institute (NEI)

Recruiting

Natural History, Pathogenesis, and Outcome of Ocular Disorders

Eye Disease

United States
National Cancer Institute (NCI)

Recruiting

Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

Lymphoma, Non-Hodgkin | Multiple Myeloma | Hodgkin Disease | Non-Small Cell Lung Cancer | Leukemia-Lymphoma, Adult T-Cell

United States
National Cancer Institute (NCI)

Recruiting

Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation

Bronchiolitis Obliterans Syndrome | Chronic Graft vs Host Disease | Chronic Graft-Versus-Host Disease

United States
National Eye Institute (NEI)

Recruiting

Rod and Cone Mediated Function in Retinal Disease

Retinal Degeneration | Retinitis Pigmentosa | Stargardt's Disease

United States
National Cancer Institute (NCI)

Recruiting

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

Neurofibromatosis 1 | Plexiform Neurofibromas

United States
National Cancer Institute (NCI)

Recruiting

Combination Nilotinib and Paclitaxel in Adults With Relapsed Solid Tumors

Solid Tumors

United States
National Cancer Institute (NCI)

Recruiting

Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Acute Leukemia | Myelodysplastic Syndrome

United States
National Cancer Institute (NCI)

Recruiting

Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib,Rituximab (TEDDI-R) in Primary CNS Lymphoma

Primary Central Nervous System Lymphoma

United States
National Cancer Institute (NCI)

Recruiting

Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors

Brain Tumor

United States
National Cancer Institute (NCI)

Recruiting

T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer

Adenocarcinoma | Advanced Non-Small Cell Lung Cancer | Squamous Cell Carcinoma | Advanced NSCLC | Adenosquamous Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer

Cancer | HIV | Chronic Granulomatous Disease | Dock 8 Deficiency

United States
National Cancer Institute (NCI)

Recruiting

Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

Stomach Neoplasms | Pancreatic Neoplasms | Thymoma | Mesothelioma | Biliary Tract Neoplasms

United States
National Cancer Institute (NCI)

Recruiting

Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer

Colorectal Neoplasms | Cholangiocarcinoma | Bile Duct Cancer | Pancreas Cancer | Gastric Neoplasms

United States
National Cancer Institute (NCI)

Recruiting

Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

MDS | Immunodeficiency | GATA2

United States
National Cancer Institute (NCI)

Recruiting

Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy

Prostatic Neoplasms | Prostate Cancer

United States
National Eye Institute (NEI)

Recruiting

Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma (MAC)

Coloboma

United States
National Cancer Institute (NCI)

Recruiting

Natural History Study of Children and Adults With Medullary Thyroid Cancer

Medullary Thyroid Cancer

United States
National Cancer Institute (NCI)

Recruiting

Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS)

KSHV Inflammatory Cytokine Syndrome (KICS) | KSHV | HHV-8

United States
National Cancer Institute (NCI)

Recruiting

Acquisition of Blood and Tumor Tissue Samples From Patients With Gastrointestinal Cancer

Gastrointestinal Cancer | Cancer of Gastrointestinal Tract | Non-GI Cancers

United States
National Cancer Institute (NCI)

Recruiting

Genetic Clues to Chordoma Etiology: A Protocol to Identify Sporadic Chordoma Patients for Studies of Cancer-Susceptibility Genes

Genes | Sporadic Chordoma

United States
Stanford University
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

Advanced Gastrointestinal Endoscopic Imaging

Gastrointestinal Diseases | Gastrointestinal Stromal Tumor (GIST) | Gastric (Stomach) Cancer

United States
National Cancer Institute (NCI)

Recruiting

Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies

Breast Cancer | Lung Cancer | Prostate Cancer | Colon Cancer | Liver Cancer

United States
National Cancer Institute (NCI)

Recruiting

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

Malignant Pleural Mesotheliomas NOS | Esophageal Cancers NOS | Lung Cancer NOS | Thoracic Cancers | Cancers of Non Thoracic Origin With Metastases to the Lungs or Pleura

United States
National Cancer Institute (NCI)

Recruiting

Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease

Chronic Graft vs. Host Disease

United States
National Cancer Institute (NCI)

Recruiting

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

Kidney Cancer | Renal Tumor Histology | Cutaneous Leiomyoma

United States
National Cancer Institute (NCI)

Recruiting

Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

Kidney Cancer | Kidney Neoplasms | Pneumothorax | FLCN Protein, Human

United States
National Cancer Institute (NCI)

Recruiting

Collection of Blood, Bone Marrow, Tumor, or Tissue Samples From Patients With Cancer to Study Drug Resistance

Renal Cell Carcinoma | Cervical Carcinoma | Lung Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Psychological Benefits of a Normalized Camping Experience for Children With Cancer

Pediatric Cancer

United States
National Cancer Institute (NCI)

Enrolling by invitation

Mobile Sensor Technologies to Assess General Symptomology of People With Cancer

Neoplasms | Lung Cancer | Prostate Cancer | Colon Cancer | Solid Tumors

United States
National Cancer Institute (NCI)

Active, not recruiting

Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination With BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) With CV301 TRICOM in Advanced Solid Tumors (STAT)

Metastatic Cancer | Solid Tumors

United States
National Cancer Institute (NCI)

Completed

Removal of the Ovaries/Fallopian Tubes and CA-125 Screening to Reduce the Risk of Ovarian Cancer in Women at Increased Genetic Risk

Breast Cancer | Ovarian Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Clinical, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Hematologic Cancer

Hodgkin Disease | Waldenstrom Macroglobulinemia | Chronic Lymphocytic Leukemia | NonHodgkin Lymphoma | Mixed Lymphoproliferative Disease

United States
National Cancer Institute (NCI)

Completed

Predictors of Relapse of Ovarian, Peritoneal, and Fallopian Tube Cancers

Peritoneal Neoplasms | Fallopian Tube Cancer | Epithelial Ovarian Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Phase I/II Study of Immunotherapy Combination BN-Brachyury Vaccine, M7824, N-803 and Epacadostat (QuEST1)

Solid Tumor | Prostate Cancer | Advanced Solid Tumor | Metastatic Prostate Cancer | Prostate Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Development of a Biologic Specimen Bank for the Study of Early Markers of Lung Cancer Among Tin Miners in Yunnan, China

Lung Cancer

China
National Cancer Institute (NCI)

Suspended

A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome

Hematopoietic Stem Cell Transplantation | Immunodeficiency

United States
National Cancer Institute (NCI)

Enrolling by invitation

Biology Studies of Hematologic Cancers

Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia | Non-Hodgkins Lymphoma | Myelodysplastic Syndrome (MDS) | Hodgkins Lymphoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Machine Learning to Analyze Facial Imaging, Voice and Spoken Language for the Capture and Classification of Cancer/Tumor Pain

Neoplasms | Cancer | Solid Tumors

United States
National Cancer Institute (NCI)

Active, not recruiting

Response-Adapted Therapy With Copanlisib and Rituximab in Untreated Follicular Lymphoma

Follicular Lymphoma | Non-Hodgkin's Lymphoma | NHL

United States
National Cancer Institute (NCI)

Enrolling by invitation

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

Lymphoma | Leukemia | Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Diffuse Large B Cell Lymphoma

United States
National Eye Institute (NEI)

Active, not recruiting

Natural History of Geographic Atrophy Associated With Age-Related Macular Degeneration

Age-Related Macular Degeneration

United States
National Cancer Institute (NCI)

Active, not recruiting

Treatment and Natural History Study of Lymphomatoid Granulomatosis

Lymphomatoid Granulomatosis | Non-Hodgkins Lymphoma | Lymphoproliferative Disorder | Granulomatosis, Lymphomatoid

United States
National Cancer Institute (NCI)

Enrolling by invitation

Collection of Blood and Urine From Patients Undergoing Radiation Therapy

Carcinoma | Cancer | Tumor

United States
National Cancer Institute (NCI)

Enrolling by invitation

Analysis of Data Collected From Individuals Administered Neurobehavioral Assessments

HIV | Neurofibromatosis Type 1 | Brain Tumors

United States
National Cancer Institute (NCI)

Active, not recruiting

Natural History Study of Patients With Neurofibromatosis Type I

Neurofibroma | Neurofibromatosis Type 1 | Malignant Peripheral Nerve Sheath Tumor | Optic Glioma | Plexiform Neurofibroma

United States
National Cancer Institute (NCI)

Completed

Esophageal Cancer Genetics Studies

Esophageal Cancer | Gastric (Cardia, Body) Cancer

China

Clinical Trials Sponsored by Liggins Institute

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Turkmenistan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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