Clinical Trials Sponsored by Lighthouse Trust

Total 6131 results

Northumbria Healthcare NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

Influence of Reliance on Historical Blood Eosinophil Counts on ICS Prescribing by GOLD 2019 Thresholds in COPD (BECCOPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Homerton University Hospital NHS Foundation Trust
Barts & The London NHS Trust

Recruiting

Function Following Laser for Anal Intraepithelial Neoplasia (FLAN) (FLAN)

Post Operative Pain | Fecal Incontinence | Anal Intraepithelial Neoplasia | Anus Cancer

United Kingdom
Manchester University NHS Foundation Trust
Northern Care Alliance NHS Foundation Trust

Active, not recruiting

A Study of Migalastat in Fabry Disease (GALAFAB)

Fabry Disease

United Kingdom
Liverpool University Hospitals NHS Foundation Trust
Manchester University NHS Foundation Trust

Completed

Eye Muscle Needle Electromyogram (EMu) Study (EMu)

Strabismus

United Kingdom
Portsmouth Hospitals NHS Trust
King's College Hospital NHS Trust; University College London Hospitals; Northern... and other collaborators

Completed

A Evaluation of the Utilisation, Effectiveness and Safety of Purastat® in the Management of Gastrointestinal Bleeding (POPS)

Gastrointestinal Bleeding

United Kingdom
University Hospital Southampton NHS Foundation...
The Leeds Teaching Hospitals NHS Trust; University of Southampton; Newcastle-upon-Tyne... and other collaborators

Recruiting

Reconstruction in Extended MArgin Cancer Surgery (REMACS)

Quality of Life | Surgery--Complications | Abdominal Cancer | Pelvic Cancer

United Kingdom
University Hospital Southampton NHS Foundation...
University Hospitals Bristol and Weston NHS Foundation Trust; Oxford University... and other collaborators

Unknown

Respiratory Syncytial Virus (RSV) and Vaccination in Pregnancy

Respiratory Syncytial Virus (RSV) | Attitude | Maternal Vaccine Exposure

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
Wellcome Trust

Recruiting

Base Edited CAR T Cells Against AML: Deep Conditioning Ahead of Allogeneic Stem Cell Transplantation (CARAML)

Relapsed Acute Myeloid Leukaemia

United Kingdom
Manchester University NHS Foundation Trust
Medtronic; Pennine Acute Hospitals NHS Trust

Recruiting

What is the Workload Burden Associated With Using the Triage HF+ Care Pathway? (TRIAGE-HF)

Heart Failure

United Kingdom
Manchester University NHS Foundation Trust
Northern Care Alliance NHS Foundation Trust

Completed

Immediate Loading of Bone Anchored Hearing Devices

Hearing Loss
University of Birmingham
Wellcome Trust; University Hospital Birmingham NHS Foundation Trust

Completed

Viability Testing and Transplantation of Marginal Livers (VITTAL)

Liver Transplantation

United Kingdom
Mid and South Essex NHS Foundation Trust
North Bristol NHS Trust

Completed

Evaluation of Spinal Cord Stimulation Pulse Rate On Clinical Outcomes (PROCO)

Back Pain | Neuralgia

United Kingdom
Sheffield Children's NHS Foundation Trust
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Psychosocial Outcomes and Transition Readiness in JIA

Juvenile Idiopathic Arthritis

United Kingdom
Heart of England NHS Trust
Sandwell & West Birmingham Hospitals NHS Trust

Completed

RESynchronisation in Patients With Heart Failure and a Normal QRS Duration (RESPOND)

Heart Failure, Congestive

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Wellcome Trust; University of Cambridge

Completed

Haemodynamic Effects of Apelin Agonists and Antagonists in Man in COPD With Raised Pulmonary Artery Pressures

Pulmonary Hypertension | COPD

United Kingdom
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Norfolk and Norwich University Hospitals... and other collaborators

Completed

Idiopathic Pulmonary Fibrosis Job Exposures Study (IPFJES)

Idiopathic Pulmonary Fibrosis | IPF

United Kingdom
Oxford University Hospitals NHS Trust
Northampton General Hospital NHS Trust; University Hospital of Wales; Royal Berkshire... and other collaborators

Terminated

Observational Study of the LMA Protector (ADEPT1)

Airway Complication of Anesthesia

United Kingdom
Northumbria University
Newcastle-upon-Tyne Hospitals NHS Trust; Gateshead Health NHS Foundation Trust and other collaborators

Active, not recruiting

CIPN in Early Stage Breast Cancer Patients

Breast Cancer | Chemotherapy-induced Peripheral Neuropathy

United Kingdom
Imperial College Healthcare NHS Trust
Cambridge University Hospitals NHS Foundation Trust; Mid and South Essex NHS...

Completed

Adherence and Acceptability of a Remote, Home-based, Pre-surgery Programme for Patients Undergoing Abdominal Aortic Aneurysm Surgery

Aortic Aneurysm, Abdominal

United Kingdom
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma (VAPOR)

Pancreatic Cancer | PDAC - Pancreatic Ductal Adenocarcinoma

United Kingdom
Imperial College Healthcare NHS Trust
Nottingham University Hospitals NHS Trust; Barts & The London NHS Trust; Hospital... and other collaborators

Completed

Ripple Mapping Guided Ablation of Ischaemic Ventricular Tachycardia. (RIPPLE-VT)

Ischemic Heart Disease | Ventricular Tachycardia

United Kingdom
Nottingham University Hospitals NHS Trust
King's College Hospital NHS Trust; The Leeds Teaching Hospitals NHS Trust; Manchester... and other collaborators

Recruiting

A Comprehensive Approach To Relief Of Digestive Symptoms In Cystic Fibrosis: CARDS-CF (CARDS-CF)

Respiratory Tract Diseases | Lung Diseases | Cystic Fibrosis | Genetic Disease | Digestive System Disease | Pancreatic Disease

United Kingdom
Queen's University, Belfast
The Leeds Teaching Hospitals NHS Trust; Cambridge University Hospitals NHS... and other collaborators

Recruiting

Co-morbidity and Refractory Asthma - UK Severe Asthma Registry (UKSAR)

Asthma

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; Nottingham University... and other collaborators

Completed

FASter Insulin in Closed-loop Technology in Children (FAST-Kids)

Type 1 Diabetes Mellitus

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust
Brighton and Sussex University Hospitals NHS Trust; University Hospitals Bristol... and other collaborators

Completed

Multicentre Randomised Clinical Trial Comparing Fixed vs Pro re Nata (PRN) Dosing of 700 μg Dexamethasone (OZDRY)

Diabetic Macular Edema

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Northumbria Healthcare NHS Foundation Trust; North East Ambulance Service NHS...

Completed

Paramedic Initiated Lisinopril For Acute Stroke Treatment (PIL-FAST)

Stroke

United Kingdom
University Hospital Southampton NHS Foundation...
Cancer Research UK; The Christie NHS Foundation Trust; Celldex Therapeutics; Oxford... and other collaborators

Active, not recruiting

A Combination of Rituximab and Varlilumab Immunotherapy in Patients With B-cell Lymphoma (RiVa)

B Cell Lymphoma

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...
Newcastle-upon-Tyne Hospitals NHS Trust; Imperial College Healthcare NHS Trust

Not yet recruiting

The RIPPLE AT-PLUS Study

Atrial Tachycardia

United Kingdom
University Hospital Southampton NHS Foundation...
Guy's and St Thomas' NHS Foundation Trust; Liverpool University Hospitals NHS...

Unknown

VEST: The UK Vedolizumab Real Life Experience Study in Inflammatory Bowel Disease (VEST)

Crohn's Disease | Ulcerative Colitis

United Kingdom
Iva Hauptmannova
International Spinal Research Trust

Recruiting

Transcutaneous Spinal Cord Stimulation With Bladder and Pelvic Floor Muscle Training

Spinal Cord Injuries

United Kingdom
King's College Hospital NHS Trust
Guy's and St Thomas' NHS Foundation Trust

Recruiting

Use of DTT to Define Facial Nerve Position in Vestibular Schwannomas

Vestibular Schwannoma

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust

Recruiting

The Effectiveness of Electronic Reminders in Improving Elastic Compliance in Orthodontic Patients

Malocclusion | Compliance, Patient

United Kingdom
St Helens & Knowsley Teaching Hospitals NHS Trust
Manchester University NHS Foundation Trust

Completed

Rehabilitating Muscle After Intensive Care (REMAIC)

Recovery From Critical Illness

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust

Unknown

Paternally Inherited Phenotypes in Cholestasis (PIP-C)

Primary Sclerosing Cholangitis | Cholestasis | Primary Biliary Cirrhosis

United Kingdom
Papworth Hospital NHS Foundation Trust
Anglia Ruskin University; Hinchingbrooke Healthcare NHS Trust

Completed

Prevalence of Obstructive Sleep Apnoea in Glaucoma (POSAG)

Open Angle Glaucoma | Obstructive Sleep Apnoea

United Kingdom
Liverpool University Hospitals NHS Foundation Trust
University Hospital Southampton NHS Foundation Trust

Completed

The Effect of Chemotherapy and Surgery for Cancer on Exercise Capacity

Tumor of Esophagus, Stomach and Duodenum

United Kingdom
Royal Marsden NHS Foundation Trust
Royal Brompton and Harefield NHS Foundation Trust

Unknown

A Prospective Longitudinal Cohort Study Looking at the Difference in Carotid Intima-medial Thickness Between Irradiated and Unirradiated Carotid Arteries in Patients With Head and Neck Cancer

Head and Neck Tumours

United Kingdom
University of Edinburgh
Wellcome Trust; NHS Lothian; Manchester University NHS Foundation Trust; Oxford... and other collaborators

Completed

Prediction of Recurrent Events With 18F-Fluoride (PREFFIR)

Myocardial Infarction | Coronary Artery Disease

United Kingdom
University Hospitals of Derby and Burton NHS Foundation...
Wellcome Trust; Nottingham University Hospitals NHS Trust; BioPhage Theraputics...

Withdrawn

Assessing the Efficacy of Anti-staphylococcal Phages in the Management of Infected Foot Ulcers in Diabetes (PDFI)

Diabetes | Diabetic Foot | Diabetic Foot Infection

United Kingdom
Manchester University NHS Foundation Trust
North West Ambulance Service nhs foundation trust

Not yet recruiting

Arterial Blood Pressure and Cardiac Arrest (ABaCAS)

Cardiac Arrest
University Hospitals Coventry and Warwickshire...
Oxford University Hospitals NHS Trust

Not yet recruiting

Physiotherapy and Optimised Nutrition in Survivors of Critical Illness (PHOENIX)

Critical Illness

United Kingdom
Northumbria University
Gateshead Health NHS Foundation Trust; Northumbria Healthcare NHS Foundation...

Recruiting

Ocular Microtremor in Parkinson's Disease. (OMTinPD)

Parkinson's Disease | Parkinson Disease

United Kingdom
South Tees Hospitals NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust

Not yet recruiting

Thrombogenicity of Lipoprotein A: Laboratory Study Defining the Prothrombotic Effects of Lipoprotein A

Cardiac Disease | Cardiovascular Disease and Lipid Disorders

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust

Recruiting

Endothelial Function, Inflammation and Organ Dysfunction in COVID-19

Shock | COVID

United Kingdom
King's College Hospital NHS Trust
Merck Sharp & Dohme LLC; Hepatitis C Trust

Terminated

ATTIC - Access To Treat in the Community (ATTIC)

Hepatitis C, Chronic

United Kingdom
University of Nottingham
Nottinghamshire Healthcare NHS Trust; Lincolnshire Partnership NHS Foundation...

Completed

Video NET With CYP Who Witnessed Domestic Violence

Domestic Violence | Trauma, Psychological | Post-Traumatic Stress Disorder in Children | Narrative Exposure Therapy | Post-Traumatic Stress Disorder in Adolescence | Post-Traumatic Stress Disorder Complex

United Kingdom
University of Oxford
Oxford University Hospitals NHS Trust; Buckinghamshire Healthcare NHS Trust

Completed

Total Hip Replacement Performance & Assessment

Hip Osteoarthritis

United Kingdom
University Hospital Southampton NHS Foundation...
Dorset HealthCare University NHS Foundation Trust

Completed

Early EMDR Following Covid-19 Critical Illness: A Feasibility Trial (Cov-EMERALD)

Depression | Anxiety Disorders | COVID | Post Traumatic Stress Disorder | Critical Care | Intensive Care Psychiatric Disorder

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust

Completed

Pregnancy Dating Test - The Fall of hPL in Urine Over Time

Miscarriage Threatening | Abortion, Complete

United Kingdom
University Hospital Plymouth NHS Trust
Torbay and South Devon NHS Foundation Trust

Completed

Does Trans-Cutaneous Electrical Nerve Stimulation (TENS) Alleviate The Pain Experienced During Bone Marrow Sampling? (TENS)

Pain

United Kingdom

Clinical Trials Sponsored by Lighthouse Trust

Sponsors and Collaborators

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Drug Interventions

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CROs in Luxembourg

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Rare Diseases

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