Search clinical trials for: open defecation

Total 8611 results

Centre Hospitalier Universitaire de Nice

Not yet recruiting

A 44-week Monocentric Open Study Assessing the Efficacy and Safety of Deucravacitinib in Adults With Inflammatory Genodermatoses (GENEPID)

Inflammatory Epidermal Genodermatoses

France
Assiut University

Not yet recruiting

Comparison of Outcomes Between Open Wedge High Tibial Osteotomy and Double Level Osteotomy in Antromedial Knee Arthritis With Extra Articular Deformity

Knee Osteoarthritis
Vanda Pharmaceuticals

Recruiting

Motion Delos: An Open Label Safety and Efficacy of Tradipitant in Participants Affected by Motion Sickness

Motion Sickness

United States
Methodist Health System

Recruiting

Penetrating Trauma Registry and Open Source Data

Penetrating Trauma Registry and Open Source Data

United States
Martina Hansen's Hospital
Oslo University Hospital; South-Eastern Norway Regional Health Authority; Lovisenberg...

Not yet recruiting

Finding the Optimal Aim of Correction in Opening Wedge High Tibial Osteotomy

Arthralgia | Osteoarthritis, Knee | Knee Pain Chronic
Center of Endourology "Endocenter"

Not yet recruiting

Hemorrhoids: Options of Traditional Hemorrhoidectomy

Hemorrhoids | Open Hemorrhoidectomy

Russian Federation
Ki Health Partners. LLC
Revance Therapeutics, Inc.; The Los Angeles Headache Center

Recruiting

Open Label, 6-month Study for High Frequency and Chronic Migraine,

Chronic Migraine, Headache

United States
Oxford University Hospitals NHS Trust
Gleamer

Recruiting

AI Assisted Detection of Fractures on X-Rays (FRACT-AI) (FRACT-AI)

Fractures, Closed | Fracture | Fractures, Open | Bone Fracture | Dislocation | Fracture Multiple

United Kingdom
Chinese University of Hong Kong

Recruiting

Open-label Pilot Study Synbiotic Treatment for Autism Spectrum Disorder

Anxiety | Autism Spectrum Disorder

Hong Kong
Liquidia Technologies, Inc.

Recruiting

An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH (ASCENT)

Pulmonary Hypertension | Interstitial Lung Disease

United States
Dan Liu

Recruiting

Diagnosis and Comprehensive Treatment of Mediastinal Interventional Technique

Mediastinal Diseases

China
Duke University

Not yet recruiting

Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252 (PuMP)

Recurrent High Grade Glioma
Gamaleya Research Institute of Epidemiology and...

Not yet recruiting

An Open-label Study of the Safety and Pharmacokinetics of the TGKP

Acute Respiratory Distress Syndrome (ARDS)
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Multicenter, Open-label Extension Study Evaluating the Efficacy and Safety of IBI311 in Subjects With Thyroid Eye Disease

Thyroid Eye Disease, TED

China
Huihua Xiong

Recruiting

The Efficacy and Safety of Utidelone Plus Tirelizumab and Bevacizumab for Advanced or Metastatic Triple-negative Breast Cancer (UTILIZABLE) ：Single-arm, Prospective, Open Clinical Study (UTILIZABLE)

TNBC - Triple-Negative Breast Cancer

China
Hospital Universitario La Fe

Recruiting

Use of Heart-lung Interaction to Predict Haemodynamic Tolerance to the Open Lung Approach With Individualised PEEP (HiPEEP)

Anesthesia | Hypovolemia | Perioperative/Postoperative Complications | Haemodynamic Instability

Spain
Janssen Research & Development, LLC

Recruiting

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib (COCOON)

Carcinoma, Non-Small-Cell Lung

United States, Taiwan, Korea, Republic of, Malaysia, Turkey, France, Spain, China, Germany, Argentina
Cabaletta Bio

Recruiting

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Nephritis

United States
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.

Recruiting

An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM

Obstructive Hypertrophic Cardiomyopathy

China
PT Bio Farma

Recruiting

Effectiveness & Safety of Ovine Enoxaparin Sodium to Originator Enoxaparin in Non-ST-Segment Elevation Acute Coronary Syndrome (NSTEACS) Patients: a Multicenter, Non-randomized, Open-label, Non-inferiority Trial

Safety Issues | Effect of Drug

Indonesia
Henry Ford Health System

Not yet recruiting

Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic Fractures

Fractures, Bone | Trauma | Opioid Use
M.D. Anderson Cancer Center

Recruiting

A Pilot, Open-Label Study of Luspatercept for Patients With Lower Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes

United States
University Hospital, Strasbourg, France

Recruiting

Chronic Anergic-anhedonic Depression Open Trial (CADOT)

Depressive Disorder, Treatment-Resistant

France
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Evaluation of the Efficacy and Safety of Interleucin-2 Combined With PD-1 Monoclonal Antibody and CAPOX in Preoperative Neoadjuvant Therapy for Locally Advanced Rectal Cancer - a Multicenter, Single-arm, Open-label Clinical Trail

Locally Advanced Rectal Adenocarcinoma
The Second Hospital of Nanjing Medical University

Recruiting

Washed Microbiota Transplantation for Chronic Constipation in Adults

Constipation

China
Centre de Médecine Intégrative et Complémentaire...

Recruiting

Conditioned Open Label Placebo for Postoperative Pain Management (COLP)

Pain, Postoperative

Switzerland
Masaryk Memorial Cancer Institute

Recruiting

Optimization of Fractionation Schedules of Heel Spur Radiotherapy Prospective Randomized Open-label Trial

Heel Spur

Czechia
Menarini International Operations Luxembourg SA

Recruiting

Open-label, Multicenter, multinAtionaL, inteRventional Clinical Trial to Assess Efficacy and Safety of the exteMporaneous combInation of Nebivolol and Ramipril in hypertenSIve pAtients (ARTEMISIA)

Hypertension

Hungary
M.D. Anderson Cancer Center
Sanofi US Services, Inc

Recruiting

Phase I/II Open Label Study of Belumosudil Mesylate Alone, and in Combination With Dexamethasone, in Patients With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
Guy's and St Thomas' NHS Foundation Trust

Not yet recruiting

The ReVo Study: Low-volume vs High-volume Rectal Irrigation (ReVo)

Constipation | Constipation - Functional | Defecation Disorder | Constipation by Outlet Obstruction
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Study Assessing Esophageal Function and Remodeling With Dupilumab Compared With Placebo for 24 Weeks Followed by 104 Weeks Open Label in Adult Participants With EoE (REMOdeling With Dupilumab in Eosinophilic Esophagitis Long-term Trial)

Eosinophilic Oesophagitis

United States, Canada, Israel
Rocket Pharmaceuticals Inc.

Recruiting

A Multi-Center, Open Label Gene Therapy Study of RP-A501 in Male Patients With Danon Disease

Danon Disease

United States
Institute of Hematology & Blood Diseases Hospital...

Recruiting

A Prospective, One-arm and Open Clinical Study of Obinutuzumab in the Treatment of Pediatric Primary Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia | Treatment

China
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

An Open Phase I Clinical Trial of SHR-1826 for Injection in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
Maastricht University Medical Center
Erasmus Medical Center; Reinier Haga Orthopedisch Centrum; VieCuri Medical Centre and other collaborators

Recruiting

Evaluating the Utility of Bone Grafts in Open Wedge Corrective Osteotomy and Plate Fixation (WOPPeR)

Malunion of Fracture of Radius

Netherlands
Qilu Hospital of Shandong University

Not yet recruiting

Randomized Controlled, Open Clinical Study on Efficacy and Safety of Acupuncture for Bladder Function Recovery After Radical Cervical Cancer Surgery

Cervical Cancer
Merz Therapeutics GmbH

Recruiting

A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve Injury (PaiNT)

Moderate to Severe Chronic Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN) or Peripheral Nerve Injury

Bulgaria, Germany, Poland, France, Hungary, Spain
Sheba Medical Center
Tel Aviv University

Recruiting

Clemastine Treatment in Individuals With Williams Syndrome

Williams Syndrome

Israel
Centre Hospitalier St Anne

Recruiting

Transcranial Ultrasonic Stimulation in Treatment-resistant Depression : an Open-label Pilot Trial (StimulUS)

Treatment Resistant Depression

France
M.D. Anderson Cancer Center

Recruiting

Combination Therapy for Cancer Related Fatigue in Patients With Metastatic Cancers

Fatigue | Metastatic Cancers

United States
Milton S. Hershey Medical Center

Recruiting

Open vs. Blind Weighing Study In Adolescents and Young Adult With Eating Disorders

Anorexia Nervosa | Eating Disorders

United States
Spectrocor

Recruiting

Spectroscopic Assessment of Intramyocardial Oxygen Saturation During Open-Heart Surgery (ECS)

Coronary Artery Disease | Heart Valve Diseases

Finland
Hanita Lenses

Recruiting

Influence of CleaRing Open-capsule Device on Refractive Predictability in Cataract Patients (Part 2) (CleaRing)

Posterior Capsule Opacification

Israel
Cancer Institute and Hospital, Chinese Academy...

Recruiting

A Prospective, Open-label, Multicenter, Randomized Controlled Phase III Study of Prophylactic Central Neck Dissection in Low-risk Papillary Thyroid Cancer

Recurrence | Thyroid Cancer

China
San Diego Sexual Medicine

Not yet recruiting

An Open-Label Study of 50 mg Oral Testosterone Undecanoate (Kyztrex) in Menopausal Women With Low Testosterone and HSDD

Hypoactive Sexual Desire Disorder

United States
Mao Jianhua
Tongji Hospital; Xinhua Hospital, Shanghai Jiao Tong University School of Medicine and other collaborators

Recruiting

Study of Adrenocorticotropic Hormone on Children With Frequent Relapse or Steroid-dependent Nephrotic Syndrome: a Prospective, Multicenter, Randomized，Open-label Clinical Trial.

Nephrotic Syndrome in Children

China
Vivacelle Bio

Not yet recruiting

A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock (VBI-S-02) (VBI-S-02)

Sepsis | Septic Shock | Hypovolemia
TWi Biotechnology, Inc.

Recruiting

An International, Multicenter, Randomized, Double-Blind, Parallel Group, Vehicle-Controlled, Phase 2/3 Study With Open-Label Extension Evaluating the Efficacy and Safety of Diacerein 1% Ointment for the Treatment of Generalized Epidermolysis Bullosa Simplex (EBS)

Generalized Epidermolysis Bullosa Simplex

United States, Taiwan, Australia, Philippines, Austria, Italy, Poland
Second Affiliated Hospital, School of Medicine,...
Changxing Branch, Second Affiliated Hospital, School of Medicine, Zhejiang... and other collaborators

Recruiting

Clinical Study of Single Incision Laparoscopic Cholecystectomy in the Treatment of Patients With Acute Cholecystitis

Cholecystectomy, Laparoscopic

China
Hangzhou Sumgen Biotech Co., Ltd.

Recruiting

An Open-label Study of SG1827 in Subjects With Advanced Solid Tumors (CSG-1827-101)

Advanced Solid Tumors

China

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