Clinical Trials Sponsored by Cure Therapeutics

Total 10937 results

Allergy Therapeutics

Completed

Dose Selection Study of Efficacy and Safety of Different Doses of Grass MATA MPL and Grass MATA Using mEECs™

Seasonal Allergic Rhinitis

United States
MC2 Therapeutics

Completed

This Trial is a Randomised, Multicentre, Investigator-blind, Vehicle and Comparator-controlled, Parallel-group Trial With the Purpose of Evaluation Efficacy, Safety and Convenience of the MC2-01 Cream

Psoriasis Vulgaris

Germany, Czechia
United Therapeutics

Completed

Dinutuximab and Irinotecan Versus Irinotecan to Treat Subjects With Relapsed or Refractory Small Cell Lung Cancer

Small Cell Lung Cancer

United States, Canada, Spain, Australia, Korea, Republic of, France, United Kingdom, Thailand, Malaysia, Hungary, Poland, Taiwan, Philippines, Hong Kong, Lithuania, Georgia, Bulgaria, India, Italy, Romania, Russian Federation, Slo... and more
Allergy Therapeutics

Terminated

Investigation of Efficacy and Safety of Tree MATAMPL,Tree MATA, and Placebo in Patients With Birch-Induced Seasonal Allergic Rhinitis

Type I Hypersensitivity

Canada
Shield Therapeutics

Unknown

Four-Way Crossover Study to Compare Ferric Maltol Capsules and Oral Suspension in Healthy Volunteers

Anemia, Iron Deficiency

United States
Shield Therapeutics

Completed

Safety and Efficacy Study of Oral Ferric Maltol Compared to Intravenous Iron To Treat Iron Deficiency Anaemia in IBD

Anemia, Iron-Deficiency | Crohn's Disease | Inflammatory Bowel Disease

United States, France, Germany, Spain, Belgium, Hungary
Shield Therapeutics

Completed

Study With Oral Ferric Maltol for the Treatment of Iron Deficiency Anemia in Subjects With Chronic Kidney Disease (AEGIS-CKD)

Renal Insufficiency, Chronic | Iron-Deficiency Anemia

United States
Effector Therapeutics

Terminated

A Dose Escalation and Cohort-Expansion Study of Oral eFT508 in Subjects With Advanced Solid Tumors

Cancer

United States
Trevi Therapeutics

Completed

Study of Nalbuphine HCl ER Tablets in Patients With Prurigo Nodularis

Pruritus | Prurigo Nodularis | Prurigo | Nodularis Prurigo

United States, Germany, Poland
Karuna Therapeutics

Completed

A Study to Assess Safety and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-1)

Schizophrenia

United States
Promethera Therapeutics

Completed

Study to Evaluate the Efficacy of HepaStem in Urea Cycle Disorders Paediatric Patients (HEP002)

Urea Cycle Disorders

Belgium, Spain, France, Poland
Promethera Therapeutics

Completed

Phase II Safety Study of 2 Dose Regimens of HepaStem in Patients With ACLF (HEP101)

Acute-On-Chronic Liver Failure

Belgium, France
RANI Therapeutics

Completed

A First-in-Human Study of the RaniPill, an Oral Drug Delivery Platform (RaniPill)

Healthy Volunteers

Australia
Nektar Therapeutics

Completed

Efficacy and Safety Study of NKTR-181 in Opioid-Naive Subjects With Low Back Pain (SUMMIT-07)

Low Back Pain | Chronic Pain

United States
PTC Therapeutics

Completed

Phase 3 Study of Ataluren in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) (ACT DMD)

Nervous System Diseases | Genetic Diseases, Inborn | Genetic Diseases, X-Linked | Musculoskeletal Diseases | Muscular Diseases | Neuromuscular Diseases | Muscular Dystrophies | Muscular Disorders, Atrophic | Muscular Dystrophy, Duchenne

United States, Spain, Korea, Republic of, Belgium, France, Canada, Australia, United Kingdom, Israel, Italy, Brazil, Chile, Czechia, Sweden, Switzerland, Turkey, Germany, Poland
Halozyme Therapeutics

Completed

PEGPH20 Plus Nab-Paclitaxel Plus Gemcitabine Compared With Nab-Paclitaxel Plus Gemcitabine in Participants With Stage IV Untreated Pancreatic Cancer

Metastatic Pancreatic Cancer

United States
Celldex Therapeutics

Completed

A Phase 1 Study of CDX-0159

Healthy Subjects

United States
Eleusis Therapeutics

Completed

A Double-blind, Placebo-controlled Study to Evaluate Very Low Dose LSD in Healthy Volunteers Aged 55-75 Years

Healthy Volunteers
Effector Therapeutics

Completed

An Open-label Study Examining the Effect of Tomivosertib (eFT508) in Patients With Advanced Castrate-resistant Prostate Cancer (CRPC)

Castrate-resistant Prostate Cancer (CRPC)

United States
Sangamo Therapeutics

Completed

Safety and Efficacy of CERE-120 in Subjects With Parkinson's Disease

Idiopathic Parkinson's Disease

United States
Blade Therapeutics

Completed

First in Human Study in Healthy Volunteers Followed With Dosing in Participants With Lung or Liver Fibrosis

Fibrosis

Australia
Therapeutics, Inc.

Completed

Comparison of 188-0551 Spray Versus Vehicle Spray in Subjects With Plaque Psoriasis (307)

Plaque Psoriasis

United States
United Therapeutics

Completed

Phase III Clinical Worsening Study of UT-15C in Subjects With PAH Receiving Background Oral Monotherapy (FREEDOM-EV)

Pulmonary Arterial Hypertension

Korea, Republic of, United States, Australia, Austria, Taiwan, China, Israel, Canada, India, Germany, Singapore, United Kingdom, Brazil, Italy, Netherlands, Argentina, Sweden, Chile, Denmark, France, Greece, Mexico, Poland
Corcept Therapeutics

Completed

Study to Evaluate CORT125134 in Participants With Cushing's Syndrome

Cushing's Syndrome

Netherlands, United States, Hungary, Italy, United Kingdom
Sangamo Therapeutics

Completed

Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Subjects

HIV Infection | HIV

United States
Corcept Therapeutics

Completed

CORT125134 Single Ascending Dose (SAD) and Multiple Ascending Dose (MAD)

Healthy

United Kingdom
Celldex Therapeutics

Completed

A Window of Opportunity Study of KTN3379 in Surgically Resectable Head and Neck Cancer Patients

Squamous Cell Carcinoma of the Head and Neck

United States
Aprea Therapeutics

Completed

Safety Study of APR-246 in Patients With Refractory Hematologic Cancer or Prostate Cancer

Prostatic Neoplasms | Hematologic Neoplasms

Sweden
Windtree Therapeutics

Terminated

Trial To Assess The Safety And Tolerability Of Lucinactant For Inhalation In Preterm Neonates 26 to 28 Weeks PMA

Respiratory Distress Syndrome

Canada, United States, Chile, Poland
Proteon Therapeutics

Completed

A Study of PRT-201 Administered Immediately After Radiocephalic Arteriovenous Fistula(AVF) Creation in Patients With Chronic Kidney Disease (CKD) (PATENCY-1)

Chronic Kidney Disease

United States
BioMimetic Therapeutics

Unknown

Long-term Safety and Effectiveness of AUGMENT® Injectable Bone Graft Compared to Autologous Bone Graft

Ankle and Hindfoot Arthrodesis
PTC Therapeutics

Withdrawn

A Study of Deflazacort (Emflaza®) in Participants With Duchenne Muscular Dystrophy (DMD) (PTCEMF)

Duchenne Muscular Dystrophy
Promethera Therapeutics

Completed

Long-term Safety Follow-up Study of Patients Having Received HepaStem (SAF001)

Urea Cycle Disorders | Crigler Najjar Syndrome

Belgium
Corcept Therapeutics

Completed

First-in-human Study in Healthy Subjects

Healthy

United Kingdom
Cyclerion Therapeutics

Completed

A Trial of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Healthy Subjects

Healthy

United States
Akebia Therapeutics

Completed

A Single Dose Study of Oral Vadadustat in Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment

United States
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Cyclosporine, Probenecid and Rifampin

Drug Interaction Potentiation

Canada
Akebia Therapeutics

Completed

A Study in Evaluating Bioequivalence of Test and Reference Vadadustat 450 MG and 150 MG Tablets and to Determine Food Effect on the 450 MG Tablet

Healthy

United States
Akebia Therapeutics

Completed

Study to Evaluate the Effect of Rabeprazole on the Pharmacokinetics of Vadadustat

Pharmacokinetics | Drug Interaction Potentiation

Canada
Corcept Therapeutics

Completed

Mass Balance Recovery and Metabolite Profile of CORT125281 in Healthy Male Participants

Healthy

United Kingdom
Intarcia Therapeutics

Terminated

Comparison of Efficacy, Safety, and Tolerability of ITCA 650 to Empagliflozin and Glimepiride as add-on Metformin

Diabetes Mellitus, Type 2

United States, Canada
Halozyme Therapeutics

Completed

Phase II Pharmacokinetics Study of Humalog and Humulin-R With and Without rHuPH20 in Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States
BioMimetic Therapeutics

Completed

Pilot Study of Augment Rotator Cuff for Surgical Treatment of Full Thickness Rotator Cuff Tears

Full Thickness Rotator Cuff Tear

Canada
Amicus Therapeutics

Approved for marketing

Physician Initiated Expanded Access Request for Migalastat in Individual Patients With Fabry Disease

Fabry Disease

United States, Australia
Placon Therapeutics

Unknown

A Study to Determine the Safety of BTP-114 for Treatment in Patients With Advanced Solid Tumors With BRCA Mutations

Breast Neoplasms | Prostatic Neoplasms | Pancreatic Neoplasms | Ovarian Neoplasms

United States
United Therapeutics

Completed

Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 Years

PAH

United States
Agile Therapeutics

Completed

Pharmacokinetic Study of AG200-15 Transdermal Patch to Three Anatomical Sites in Healthy Females

Healthy

United States
BioMimetic Therapeutics

Completed

Augment® Injectable Bone Graft Compared to Autologous Bone Graft as a Bone Regeneration Device in Hindfoot Fusions

Arthritis | Osteoarthritis | Rheumatoid Arthritis | Degenerative Joint Disease | Congenital Deformity

United States, Canada
Heron Therapeutics

Completed

Bupivacaine HCl PK and Safety in Augmentation Mammoplasty

Analgesia

United States
Akebia Therapeutics

Completed

Relative Bioavailability of Two Formulations of AKB-6548 and the Food Effect of a New Tablet in Healthy Adult Subjects

Healthy

United States

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