Search clinical trials for: Cytochrome p450 CYP2C19 (Human)

Total 26254 results

Markus Joerger
University of Basel

Completed

Cytochrom p450 3A4 and 1A2 Phenotyping for the Individualization of Treatment With Sunitinib or Erlotinib in Cancer Patients

Non Small-cell Lung Cancer | Renal-cell Cancer | Gastrointestinal Stroma Tumor

Switzerland
Yonsei University

Completed

Effect of CYP2C9/CYP2C19 Polymorphism on Pharmacokinetics of Phenobarbital in Korean Neonatal Seizure Patients.

Neonatal Seizure
University Hospital, Basel, Switzerland

Completed

In Vivo Determination of Cytochrome P450 Activities in Patients With Liver Cirrhosis (CombiCapsLC)

Liver Cirrhosis

Switzerland
Janssen-Cilag International NV

Completed

A Clinical Trial Comparing the Efficacy of Darunavir/Ritonavir Monotherapy Versus a Triple Combination Therapy Containing Darunavir/Ritonavir and 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Patients With Undetectable Plasma HIV-1 RNA on Current Treatment (PROTEA)

Human Immunodeficiency Virus (HIV) Infections | Acquired Immunodeficiency Syndrome (AIDS) Virus

France, United Kingdom, Belgium, Germany, Spain, Switzerland, Denmark, Israel, Austria, Poland, Hungary, Sweden, Ireland
NEMA Research, Inc.

Completed

Cytochrome P450 Pharmacokinetic DDIs Among Patients With Chronic Low Back Pain Taking Opioids

Chronic Low Back Pain
National Health Research Institutes, Taiwan
Mackay Memorial Hospital; Chang Gung Memorial Hospital; National Science Council... and other collaborators

Completed

Clinical Pharmacogenomics of Antidepressant Response

Depression

Taiwan
Pfizer

Active, not recruiting

Study to Evaluate the Efficacy and Safety of PF-07055480 / Giroctocogene Fitelparvovec Gene Therapy in Moderately Severe to Severe Hemophilia A Adults (AFFINE)

Hemophilia A

Spain, Taiwan, Australia, United States, Japan, France, Turkey, Germany, Korea, Republic of, United Kingdom, Saudi Arabia, Canada, Greece, Sweden, Brazil, Italy
University of Pennsylvania

Completed

Testing the Persuasiveness of Pro-inoculation Arguments

Vaccine Refusal | Vaccination Hesitancy | Human Papillomavirus Vaccination

United States
Public Health England

Completed

Observational Follow up of Prior HPV Vaccinees (HPVfollowup)

Human Papillomavirus Virus

United Kingdom
GlaxoSmithKline

Completed

First Study in Humans With GSK424887

Depressive Disorder and Anxiety Disorders

United Kingdom
Emergent BioSolutions
National Institutes of Health (NIH)

Completed

Safety and Pharmacokinetics Study of Anthrax Immune Globulin Intravenous (AIGIV)

Anthrax

United States
Jordi Carratala
Institut d'Investigació Biomèdica de Bellvitge; Instituto de Salud Carlos III

Unknown

Effect of Albumin Administration in Hypoalbuminemic Hospitalized Patients With Community-acquired Pneumonia. (ALBUCAP)

Hypoalbuminemia | Community-acquired Pneumonia

Spain
Musculoskeletal Transplant Foundation
Washington University School of Medicine; Pines Surgical; Meridian Healthcare...

Completed

Multi-Center Study To Examine The Use Of Flex HD® And Strattice In The Repair Of Large Abdominal Wall Hernias

Hernia of Abdominal Wall

United States
University Medicine Greifswald
Botiss Medical AG

Terminated

Alveolar Management Following Teeth Extraction

Bone Resorption | Alveolar Bone Loss

Germany
National Institutes of Health Clinical Center (CC)

Completed

Effect of Genetics on Metabolism of Efavirenz

Metabolism

United States
Milton S. Hershey Medical Center
National Cancer Institute (NCI)

Active, not recruiting

HPV Vaccine Communication ECHO for Primary Care Clinics

Human Papillomavirus Vaccines | Adolescent Health Services

United States
Mutual Pharmaceutical Company, Inc.

Completed

Drug - Drug Interaction Study Between Quinine Sulfate and Theophylline

Pharmacokinetics

United States
National Institute of Allergy and Infectious Diseases...

Completed

Influenza A H3N2 Human Challenge Study in Healthy Adult Volunteers

Determine Minimally to Moderately Infective Dose (MMID) of Influenza A H3N2

United States
Vitrolife

Completed

Adding Antioxidants Into Human Sequential Culture Media System (Antioxidants)

Blastocyst | Human | Antioxidants | Oxygen | Culture Media | Embryo

Japan
Columbia University

Recruiting

Targeted Fortification of Donor Breast Milk in Preterm Infants

Growth Failure | Growth Retardation | Prematurity; Extreme | Infant Nutrition Disorders | Failure to Thrive in Newborn

United States
University of Tennessee

Completed

Alcohol Inhibits Drug Metabolism by Carboxylesterases

Drug Interactions

United States
Wageningen University
FrieslandCampina

Recruiting

Milk and Plant Protein Digestion (MAPP-D)

Food Digestion

Netherlands
Kingston University

Completed

The Role of Physical Activity and Diet Within Pulmonary Sarcoidosis

Interstitial Lung Disease | Sarcoidosis | Sarcoidosis, Pulmonary | ILD

United Kingdom
Hoffmann-La Roche

Terminated

A Phase II Study Comparing The Efficacy Of Venetoclax + Fulvestrant Vs. Fulvestrant In Women With Estrogen Receptor-Positive, Her2-Negative Locally Advanced Or Metastatic Breast Cancer Who Experienced Disease Recurrence Or Progression During Or After CDK4/6 Inhibitor Therapy (Veronica)

Estrogen Receptor-positive (ER+)/Human Epidermal Growth Factor Receptor (HER2)-Negative Locally Advanced or Metastatic Breast Cancer

Canada, United States, United Kingdom, Australia, Germany
Tuğba Sarı

Completed

The Effect of Education Given to Pregnancy on Prenatal Attachment, Anxiety and Fear of Birth

Fear of Childbirth

Turkey
Indiana University

Terminated

IU Health Krannert Personalized Medicine Study

Coronary Artery Disease

United States
Dokuz Eylul University
University of Liverpool

Unknown

Influence of CYP2C19 Genotype on Safety and Efficacy of Voriconazole in Pediatric Patients With Hematologic Malignancy

Adverse Drug Reactions

Turkey
Hoffmann-La Roche

Completed

A Study of RO5186582 Treatment on Cytochrome P450 (CYP) 3A4 Activity in Healthy Participants

Healthy Volunteer

United Kingdom
Repros Therapeutics Inc.

Completed

Assessment of Drug-Drug Interactions of Androxal With Cytochrome P450 Isoenyzmes in Healthy Males

Drug-drug Interaction

United States
Wageningen University

Completed

MRI Exploration of Protein Digestion (MOVE)

Gastric Digestion

Netherlands
Jules Desmeules

Completed

Cocktail Approach for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spot

Healthy Volunteers

Switzerland
NEMA Research, Inc.

Completed

Prevalence of Potential Cytochrome P450 Pharmacokinetic Incident Drug-Drug Interactions(DDI) Among Osteoarthritis Patients

Osteoarthritis
Indiana University
National Institutes of Health (NIH); National Institute of General Medical...

Completed

Determine the Effects of Gene Differences and Voriconazole on Enzyme CYP2B6 Activity in the Liver in Healthy Volunteers

Efavirenz, Metabolism and Pharmacokinetics Changes

United States
Baker Heart and Diabetes Institute

Completed

Polycystic Ovary Syndrome - Improving Outcomes

Polycystic Ovary Syndrome

Australia
University of Alabama at Birmingham

Not yet recruiting

Optimizing Human Milk Intake for Growth and Gut Health in Very Preterm Infants

Prematurity
National Taiwan University Hospital

Unknown

The Role of CYP2C19 on the Eradication of H. Pylori Infection:Implication of PK/PD Relationships

Peptic Ulcer With H. Pylori Infection | Gastritis With H. Pylori Infection

Taiwan
Mallinckrodt

Terminated

Topical Raplixa for Surgical Bleeding in Children

Surgical Bleeding

United States
Celgene

Completed

A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677

Healthy Volunteer

United Kingdom
University of Sarajevo
Wellcome Trust; University of Dundee; General Hospital Prim. Dr. Abdulah Nakas

Completed

Interaction Between Omeprazole and Gliclazide in CYP2C19 Normal/ Ultrarapid Metabolisers (INTERGLIKOM)

Diabetes Mellitus, Type 2

Bosnia and Herzegovina
National Cerebral and Cardiovascular Center

Completed

The Influence of CYP2C19 Polymorphism and Clinical Outcomes in Stroke Patients

Platelet Aggregation Inhibitors
National Taiwan University Hospital

Completed

CYP2C19 Genetic Polymorphism on the Accuracy of Proton-Pump Inhibitor Testing

GERD

Taiwan
Amgen

Active, not recruiting

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of Rotarix TM in Taiwanese Infants Who Received Hepatitis B Immunoglobulin After Birth.

Infections, Rotavirus

Taiwan
GlaxoSmithKline

Completed

Study to Assess the Safety of GSK Biologicals' Liquid Human Rotavirus Vaccine in Healthy Infants

Infections, Rotavirus

China
Istanbul Okan Univesitesi
Sakarya University

Not yet recruiting

The Effect of Motivational Interviewing on Treatment Adherence, Self-Efficacy, and Satisfaction in Individuals With Diabetic Foot Ulcers

Foot Ulcer, Diabetic
Assaf-Harofeh Medical Center

Unknown

Correlation Between CYP2C19 Genotype, Level Of Clopidogrel Metabolite And Platelet Inhibition Status

PRIMARY FOCUS:PATIENT THAT TAKE CLOPIDOGREL

Israel
Oslo University Hospital

Unknown

Monitoring of Needle-placement With Multiple Frequency Bioimpedance Monitoring

Electric Impedance | Human | Nerve | Hypodermic Needles | Tissues

Norway
Appalachian State University
Dole Food Company

Completed

Vitamin D2, Muscle Damage, NASCAR Pitcrew

Muscle Soreness | Vitamin D Status | Muscle Function

United States
Wageningen University
Tate & Lyle

Completed

Brain and Glycemic Responses to Sweet Soft Drinks (SWEETBRAIN)

Normal Physiological Response to Sweet Drinks

Netherlands
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Immune Response, and Efficacy of Gardasil (V501, qHPV) in Mid-Adult Women (V501-019)

Prevention | Papillomavirus Infection | Healthy Adult Female Participants | Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18

Search clinical trials for: Cytochrome p450 CYP2C19 (Human)

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