Search clinical trials for: High risk malignancies

Total 33731 results

University of California, San Francisco
Jazz Pharmaceuticals

Not yet recruiting

Defibrotide Prophylaxis of Transplant Associated-Thrombotic Microangiopathy for Neuroblastoma

Thrombotic Microangiopathies | Neuroblastoma | High-risk Neuroblastoma | Transplant-Associated Thrombotic Microangiopathy

United States
National Cancer Institute (NCI)

Recruiting

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Neuroblastoma | Ganglioneuroblastoma, Nodular

United States
University of Chicago

Not yet recruiting

Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues

Multiple Sclerosis | Obesity | Obesity, Morbid | Obese | Long COVID | Long Covid19 | Acute Leukemia in Remission
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Postoperative CCRT Followed by Immunotherapy in High-Risk LA HNSCC

Head and Neck Squamous Cell Carcinoma

China
National Cancer Institute (NCI)

Recruiting

Comparing the Combination of Selinexor-Daratumumab-Velcade-Dexamethasone (Dara-SVD) With the Usual Treatment (Dara-RVD) for High-Risk Newly Diagnosed Multiple Myeloma

Multiple Myeloma

United States
Ohio State University

Recruiting

Feasibility Trial of a Single Session of Crisis Response Planning for Youth at High Risk for Suicide

Suicide Prevention

United States
Stony Brook University
The University of Texas Health Science Center at San Antonio

Recruiting

Definitive Radiation for High-Risk Spine Metastases

Metastatic Cancer | Metastatic Lung Cancer | Metastatic Breast Cancer | Metastasis | Spine Metastases | Metastatic Tumor | Metastatic Tumor of Bone | Metastatic Tumor to the Spine

United States
CHX Technologies Inc.
The Research Institute of St Joe's Hamilton; St. Joseph's Health System - Centre...

Not yet recruiting

A Pilot Observation and Feasibility Study of Prevora, Integrated Into Homecare Visits of High-risk Adults

Dialysis | COPD (Chronic Obstructive Pulmonary Disease) | Chronic Metabolic Disorder | CHF (Congestive Heart Failure)
San Diego State University
University of California, San Diego

Recruiting

eSTEP: An Integrated mHealth Intervention to Engage High-risk Individuals Along the Full PrEP Care Continuum (eSTEP)

Pre-Exposure Prophylaxis (PrEP)

United States
Antonio M Jimenez Jimenez
AbbVie

Not yet recruiting

Venetoclax in Combination With Azacitidine (VEN/AZA) Followed by Donor Lymphocyte Infusion (DLI) for Patients With Very High-Risk Acute Myeloid Leukemia (AML) Undergoing Allogeneic Hematopoietic Cell Transplant (HCT)

Acute Myeloid Leukemia

United States
Washington University School of Medicine
The Leukemia and Lymphoma Society; Rising Tide Foundation; St. Louis Children...

Recruiting

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML (ABCD-NK)

Acute Myeloid Leukemia | Aml | AML, Childhood | Acute Myeloid Leukemia, Pediatric

United States
Hospices Civils de Lyon

Not yet recruiting

Impact of Non-invasive Individualized Goal-directed Fluid Therapy on Outcomes Following Thoracic Cancer Surgery (GDFT-TCS)

High-risk Thoracic Cancer Surgery

France
OHSU Knight Cancer Institute
Oregon Health and Science University; Kuni Foundation

Recruiting

Atorvastatin for Preventing Disease Metastasis in Patients With Resected High-Risk Stage IIA Melanoma

Clinical Stage IIA Cutaneous Melanoma AJCC v8

United States
Johns Hopkins University
Patient-Centered Outcomes Research Institute; Children's Hospital of Philadelphia and other collaborators

Not yet recruiting

Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

Suicide, Attempted | Suicide | Suicide Ideation | Suicide Prevention
Mayo Clinic

Recruiting

A Prospective Registry for Patients at High-Risk for Pancreatic Cancer

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma | PDAC | PDAC - Pancreatic Ductal Adenocarcinoma

United States
Maxima Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Continuous Non-invasive Electrophysiological Monitoring in High Risk Pregnancies (NIEM-O)

Preterm Birth | High Risk Pregnancy | Perinatal Outcomes

Netherlands
University of California, San Francisco

Not yet recruiting

Preoperative Prophylactic Antibiotic Duration in Moderate to High Risk Ureteroscopy

Nephrolithiasis | Infections, Urinary Tract

United States
GluBio Therapeutics Inc.

Recruiting

A Study of GLB-001 in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher Risk Myelodysplastic Syndromes

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United States
Niguarda Hospital

Recruiting

Ultrasound-assisted, Catheter-directed Thrombolysis for Acute Intermediate-high-risk Pulmonary Embolism (USAT IH-PE)

Pulmonary Embolism

Italy
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

Non-Invasive Biomarkers in Prostate Cancer Disease Management

Prostate Cancer

United States
Wuhan Union Hospital, China

Recruiting

Study to Evaluate the Safety and Efficacy of Daratumumab and Carfilzomib-based Induction/Consolidation/Maintenance Therapy in Transplant-eligible, Ultra High-risk, Newly Diagnosed Multiple Myeloma

Multiple Myeloma | Extramedullary Multiple Myeloma | Primary Plasma Cell Leukemia

China
Regeneron Pharmaceuticals

Not yet recruiting

A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma (LINKER-MGUS1)

Monoclonal Gammopathy of Undetermined Significance (MGUS) | Smoldering Multiple Myeloma (SMM)
IIMC, Riphah International University, Pakistan

Not yet recruiting

The Impact of Vitamin D Supplementation on Pregnant Women With the Risk of GDM

Gestational Diabetes Mellitus

Pakistan
Tianjin Third Central Hospital
BGI, China

Recruiting

A Prospective Study on the Application of Liquid Biopsy in the Surveillance of High-risk Population of HCC.

Hepatocellular Carcinoma

China
Institute of Tropical Medicine, Belgium
University of Manitoba; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Monkeypox, Biology, Outcome, Transmission and Epidemiology -Prospective Follow-up of High-risk Contacts (MBOTE-CONTACT)

Mpox

Congo, The Democratic Republic of the
Boston Scientific Corporation

Recruiting

VITALYST Early Feasibility Study in High-Risk PCI Patients (VITALYST EFS) (VITALYST EFS)

Heart Disease, Coronary | High-risk Percutaneous Coronary Intervention

United States, Sweden
University of Oklahoma

Not yet recruiting

Relugolix + Enzalutamide Study in High-Risk Prostate Cancer

Androgen Deprivation Therapy | Locally Advanced Prostate Cancer

United States
Karabuk University

Recruiting

Sexual Function in High-risk Pregnant Women

Anxiety | Sexual Dysfunction | High Risk Pregnancy | Female Sexual Function

Turkey
International Vaccine Institute
London School of Hygiene and Tropical Medicine; Karolinska Institutet; Centers...

Not yet recruiting

Global Burden Estimation of Human Papillomavirus (GLOBE-HPV) (HPV)

HPV Infection

Zambia, Bangladesh, Congo, The Democratic Republic of the, Ghana, Nepal, Pakistan, Sierra Leone, Tanzania
University of Kansas Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Relugolix in Combination With Radiation Therapy for Treating Patients With High Risk Prostate Cancer

Stage IV Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8

United States
Peking University People's Hospital

Not yet recruiting

Endometrial Cancer Screening in High-risk Populations

Cancer Screening
Dana-Farber Cancer Institute

Recruiting

Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma | Pancreatic Neoplasm | PDAC | PDAC - Pancreatic Ductal Adenocarcinoma

United States
Novo Nordisk A/S
Duke Clinical Research Institute

Not yet recruiting

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack (ARTEMIS)

Cardiovascular Risk | Acute Myocardial Infarction (AMI)

Canada, China, United States, Germany, Spain, Korea, Republic of, Netherlands, Australia, Italy, Denmark, India, United Kingdom, Argentina, Turkey, Mexico, Malaysia, Czechia, Poland, Brazil, France, Japan, Bulgaria, Greece, Israel
Xuesong Li

Recruiting

Combined Postoperative Radiotherapy With Kidney Sparing Surgery for Locally Advanced High-risk Ureteral Cancer

Urothelial Carcinoma Ureter | Locally Advanced

China
Fudan University

Recruiting

Postoperative Chemotherapy With/Without Radiotherapy and Immunotherapy for Colorectal Liver Metastases With High Risk of Locally Recurrence (IMPROVE)

Colorectal Cancer | Liver Metastases | Radiotherapy | Immunotherapy

China
University Hospital, Geneva

Recruiting

Neuro-biomechanical Determinants for Motor Behavior in High-risk Infants (BAMBI)

Nervous System Diseases | Cerebral Palsy | Brain Injuries | Premature Birth | Neurodevelopmental Disorders

Switzerland
FANG HE

Recruiting

Aspirin Discontinuation in High-Risk Pregnant Women of Preeclampsia

Preeclampsia | Perinatal Haemorrhage

China
Columbia University

Not yet recruiting

Telehealth-Based Intervention to Detect and Manage Glaucoma Among High-Risk Populations (NYC-SIGHT-2)

Adherence to In-Office Glaucoma Evaluation Appointment
Shanghai Hengrui Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study of SHR-2005 Intravesical Instillation in the Treatment of High-risk Non-muscle Invasive Bladder Cancer (NMIBC)

High-risk Non-muscle Invasive Bladder Cancer

China
Anhui Provincial Hospital

Recruiting

Safety and Efficacy of Unrelated Umbilical Cord Blood Microtransplantation in Patients With Higher-risk MDS

Myelodysplastic Syndromes

China
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Physiologic Markers of Cardiometabolic Risk in People With Type 1 Diabetes

Obesity | type1diabetes

United States
H. Lee Moffitt Cancer Center and Research Institute
Kite, A Gilead Company

Recruiting

Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL

Large B-cell Lymphoma | Relapsed Non-Hodgkin Lymphoma

United States
Fujian Cancer Hospital

Not yet recruiting

A Predictive Model for Early Metastasis in Cervical Cancer Patients After Radiotherapy

Cervical Cancer | Radiotherapy | Risk Factor | Prognostic Model | Distant Metastasis

China
Carl Ola Landgren, MD, PhD
Janssen Scientific Affairs, LLC

Recruiting

Teclistamab or Talquetamab in Combination With Daratumumab for High-Risk Smoldering Myeloma (REVIVE Study) (REVIVE)

Multiple Myeloma

United States
Kırıkkale University

Recruiting

Balance, Walking Speed, Quadriceps Femoris Muscle Strength and Quality of Life in Falling and Non-falling Individuals With COPD

Copd

Turkey
Second Affiliated Hospital, School of Medicine,...

Recruiting

Oriental Intervention for Enhanced Neurocognitive Health (Orient) Diet in Populations With High Risk of Stroke (ENDS)

High Risk of Stroke

China
Shanghai First Maternity and Infant Hospital

Recruiting

Prediction of Placental Fetal Growth Restriction in High Risk Population (PoPFGR)

Fetal Growth Retardation

China
National Cancer Centre, Singapore
Tan Tock Seng Hospital; BeiGene

Not yet recruiting

Tislelizumab and Metronomic Capecitabine as Maintenance in High-risk Locoregionally-advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

Singapore
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Tongji Hospital; Hunan Cancer... and other collaborators

Recruiting

Reduced-dose RT With/Without CCT Versus Standard CCRT for High-risk LANPC Who Achieved CR Post Induction Chemotherapy

Nasopharyngeal Carcinoma | De-escalation Therapy

China
Swiss Group for Clinical Cancer Research

Recruiting

LIBERTY: Liquid Biopsy to Diagnose and Monitor CNS Involvement in High-risk B Cell Non-Hodgkin Lymphoma (SAKK 38/23)

Non-hodgkin Lymphoma, B Cell

Switzerland

Search clinical trials for: High risk malignancies

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