Search clinical trials for: open label

Total 9441 results

Spaulding Rehabilitation Hospital
National Institute on Drug Abuse (NIDA)

Recruiting

Conditioning & Open-Label Placebo (COLP) for Opioid Management in Intensive Inpatient Rehabilitation

Burns | Spinal Cord Injuries | Polytrauma

United States
liberDi Ltd.

Not yet recruiting

A Prospective, Open-label, Multi-center Pilot Study to Evaluate the Safety, Feasibility and Usability of the IDA (CSP-027-21)

Chronic Kidney Disease Stage V
Sun Yat-sen University

Recruiting

Chemoradiotherapy Plus Anti-PD1 in Recurrent NPC: A Multicenter, Open-label, Randomised, Controlled, Phase III Trial

Nasopharyngeal Carcinoma

China
The University of Hong Kong
Storz Medical AG

Recruiting

Transcranial Pulse Stimulation Open-label Self-controlled Trial For Mild Neurocognitive Disorder

Mild Neurocognitive Disorder

Hong Kong
Chinese PLA General Hospital

Recruiting

An Open-label, Phase I/II Study of PLENA Regimen in Patients With Unresectable Pancreatic Cancer or BTC

Pancreatic Cancer | Biliary Tract Cancer

China
M.D. Anderson Cancer Center

Recruiting

Non-randomized, Open-label Study of Intralesional Nivolumab for High Risk Oral Premalignant Lesions

Head and Neck Cancer

United States
Betta Pharmaceuticals Co., Ltd.

Recruiting

A Phase 1，Open-label Study of BPI-421286 in Subjects With Advanced Solid Tumors

Metastatic Cancer | Malignant Neoplasms

China
Evaxion Biotech A/S
Merck Sharp & Dohme LLC

Recruiting

A Single Arm Trial Evaluating the Efficacy and Safety of EVX-01 in Combination With Pembrolizumab in Adults With Unresectable or Metastatic Melanoma

Melanoma Stage IV | Melanoma Stage III

Australia
ImCheck Therapeutics
ILife Consulting; Exystat

Recruiting

Phase 1/2a Study of ICT01 Plus Low Dose SC IL-2 in Patients With Advanced Solid Tumors (EVICTION-2)

Solid Tumor, Adult

France
National Taiwan University Hospital

Recruiting

A Single Center, Randomized, Open Label, Parallel Group, Phase 3 Study to Evaluate the Efficacy of Dapagliflozin in Subjects With Nonalcoholic Fatty Liver Disease

Fatty Liver

Taiwan
Belgian Inflammatory Bowel Disease Research and...
Janssen Cilag N.V./S.A.

Recruiting

An Open-Label Extension and Long-term Efficacy and Safety Monitoring Study of Patients With Crohn's Disease Previously Included in the Loss of RESponse to Ustekinumab Treated by Dose Escalation Study (REScUE-OLE)

Crohn Disease

Belgium
Anwita Biosciences
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Phase 1 First-in-human Study of JS014

Lymphoma | Solid Tumor, Adult | Neoplasm Malignant | Neoplasm, Experimental

Taiwan
University of Miami
ADC Therapeutics S.A.

Recruiting

Open-label of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Marginal Zone Lymphoma

Marginal Zone Lymphoma

United States
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Phase 1, Open-label, Multicenter, Dose Escalation Study of IBI363 (PD1-IL2m) in Subjects With Advanced Solid Malignancies or Lymphomas

Solid Malignancies or Lymphomas

Australia
National Taiwan University Hospital

Recruiting

A Phase I, Open-label Study to Assess the Safety and Efficacy of Poly-ICLC Plus Nivolumab in Unresectable Hepatocellular Carcinoma Patients

Hepatocellular Carcinoma

Taiwan
DHR Health Institute for Research and Development

Recruiting

PROSPECTIVE OPEN LABEL CLINICAL TRIAL TO ADMINISTER A BOOSTER DOSE OF PFIZER/BIONTECH OR MODERNA COVID-19 VACCINE IN HIGH-RISK INDIVIDUALS

COVID-19 | SARS CoV 2 Infection

United States
Assistance Publique - Hôpitaux de Paris
BioMérieux

Recruiting

Use of MULTIplex PCR, Procalcitonin, and Sputum Appearance to Reduce Duration of Antibiotic Therapy During Severe COPD EXAcerbation: A Controlled, Randomized, Open-label, Parallel-Group, Multicenter Trial (MULTI-EXA)

Acute Exacerbation of COPD

France
ViGenCell Inc.

Not yet recruiting

A Prospective, Open Label, Dose-escalation, SAD/MAD, Multicenter, 24weeks, Phase I/IIa Clinical Trial to Evaluate the Safety, Tolerability and Pharmacodynamics of Investigational Product (VM-001) in Patients With Graft-versus-host Disease(GvHD)

Graft Versus Host Disease
Szeged University

Recruiting

Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in Diabetic Leg Ulcers

Leg Ulcer | Diabetic Foot Ulcer | Mesenchymal Stem Cells | Autologous Adipose Stromal Vascular Fraction | Adipose-Derived Mesenchymal Stem Cells

Hungary
BioAtla, Inc.

Recruiting

A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Head and Neck Cancer | Metastatic Cancer | Squamous Cell Carcinoma of Head and Neck | Recurrent Squamous Cell Carcinoma of the Head and Neck | Metastatic Squamous Cell Carcinoma of the Head and Neck

United States
Newronika

Not yet recruiting

An Open-label Clinical Trial to Compare the Safety and Effectiveness of Adaptive Versus Conventional Deep Brain Stimulation (ADVENT)

Parkinson Disease
Fudan University

Recruiting

Capecitabine Combined With Lenvatinib and Tislelizumab as Adjuvant Treatment After Resection in Patients With BTC

Biliary Tract Cancer

China
Intergroupe Francophone de Cancerologie Thoracique

Recruiting

De-escalation Immunotherapy mAintenance Duration Trial for Stage IV Lung Cancer Patients With Disease Control After Chemo-immunotherapy Induction (DIAL)

Metastatic NSCLC

France
Donald Jeffrey Newport
Sage Therapeutics

Recruiting

An Open Label Pilot Study of IV Brexanolone for the Treatment of Post-Traumatic Stress Disorder

Post-Traumatic Stress Disorder

United States
Hangzhou Tangji Medical Technology Co., Ltd.

Not yet recruiting

Tangji EU Gastric Bypass Stent Study for Obesity

Obesity
Li Zhang, MD

Recruiting

An Open Label, Multicenter Phase 2 Study of Durvalumab (MEDI4736) + Olaparib as Maintenance Therapy in Chinese

Small Cell Lung Cancer | Lung Cancer | Durvalumab

China
GlaxoSmithKline
Iqvia Pty Ltd

Recruiting

An Open-Label Extension Study of GSK3511294 (Depemokimab) in Participants Who Were Previously Enrolled in 206713 (NCT04719832) or 213744 (NCT04718103) (AGILE)

Asthma

United States, Australia, Canada, France, Germany, Italy, Japan, Poland, Spain, China, Czechia, Hungary, Taiwan, United Kingdom
Charitable Union for the Research and Education...

Recruiting

Efficacy of RestoreX Penile Traction Therapy In Preserving Erectile Function Post-Prostatectomy

Erectile Dysfunction Following Radical Prostatectomy

United States
Marina Ramsis Aziz Ghaly

Recruiting

Lidocaine Spray 10% Versus Oral Ibuprofen Tablets in Pain Control During Copper Intrauterine Device Insertion

Lidocaine Toxicity

Egypt
Medical University of Silesia
Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology,...

Recruiting

The Assessment of Immune Response in Newly Diagnosed Glioblastoma Patients Treated With Pembrolizumab (PIRG)

Newly Diagnosed Glioblastoma

Poland
Virogin Biotech Canada Ltd

Recruiting

An Open-Label, Multiple-Center, Phase IIa/IIb Clinical Trial to Evaluate the Efficacy, Safety and Tolerability of VG161 as Monotherapy and in Combination With Nivolumab for Treatment of Patients With Hepatocellular Carcinoma or Intrahepatic Cholangiocarcinoma

Hepatocellular Carcinoma | Intrahepatic Cholangiocarcinoma

United States
Ain Shams University

Recruiting

Ilioinguinal Nerve Block in Transcatheter Aortic Valve Implantation

Anesthesia

Egypt
Novartis Pharmaceuticals

Recruiting

A 24-week Prospective, Open-label, Multicenter, Single-arm rPMS Study in Real-world Setting for Atectura®

Asthma

Korea, Republic of
Tianjin Medical University Cancer Institute and...

Recruiting

GEMOX Combined With Targeted Therapy and Immunotherapy for Patients With Advanced Cholangiocarcinoma

Cholangiocarcinoma

China
Samsung Medical Center

Recruiting

Open Label RCT for Chronic Severe AR : Entresto vs. CCB/ARB (REVERSE-AR)

Aortic Valve Insufficiency

Korea, Republic of
CAGE Bio Inc.
John Peter Smith Hospital

Recruiting

An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection

Fungal Infection | Onychomycosis | Tinea Unguium

United States
IntraGel Therapeutics

Not yet recruiting

A Single Arm, Prospective, Open Label, Multi Center, Phase Ib Study to Evaluate the Safety, Tolerability and Initial Efficacy of a Single Intra-tumoral Injection of IntraGel's Polymer-based Cisplatin-loaded Gel (TumoCure) in Subjects With Progressive or Radio-resistant Primary Head and Neck Tumor

Head and Neck Cancer

Israel
AstraZeneca

Recruiting

A 24-Week Efficacy and Safety Study to Assess Budesonide and Formoterol Fumarate Metered Dose Inhaler in Adult and Adolescent Participants With Inadequately Controlled Asthma (VATHOS) (VATHOS)

Asthma

United States, Canada, Italy, Japan, Vietnam, Spain, Germany, Malaysia
Taipei Veterans General Hospital, Taiwan

Recruiting

Sequencing and Combination of Mirabegron and TTNS in Overactive Bladder Syndrome: a Multicenter, Randomized, Open-label, Crossover Trial

Overactive Bladder Syndrome

Taiwan
Verrica Pharmaceuticals Inc.
Instat Clinical Research; HeartcoR Solutions; Myonex; Vial Health Technology, Inc

Recruiting

Open-Label Proof of Concept Study of VP-315 in Basal Cell Carcinoma

Carcinoma | Skin Cancer | Basal Cell Carcinoma | Cancer of the Skin, Basal Cell | Cancer of the Skin

United States
Institut Bergonié
Ipsen; MSD France

Recruiting

Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas (PEMBROCABOSARC)

Osteosarcoma | Ewing Sarcoma | Soft Tissue Sarcoma Adult | Undifferentiated Pleomorphic Sarcoma | Advanced Soft-tissue Sarcoma

France
Centre for Addiction and Mental Health

Recruiting

Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression (DEEPP)

Suicidality | Bipolar Disorder (BD)

Canada
Eucure (Beijing) Biopharma Co., Ltd

Recruiting

A Study to Evaluate the Combination of YH003, YH001 and Pembrolizumab in Subjects With Advanced Solid Tumors

Solid Tumor

Australia
Fudan University
Merck Sharp & Dohme LLC

Recruiting

Induction of Cisplatin/Nab-paclitaxel/Pembrolizumab Followed by Olaparib/Pembrolizumab Maintenance in mTNBC Patients

Triple Negative Breast Cancer

China
Fulcrum Therapeutics

Recruiting

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of FTX-6058

Sickle Cell Disease | Sickle Cell Anemia

United States
Szeged University

Recruiting

Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in Chronic Non-Healing Venous Leg Ulcers

Mesenchymal Stem Cells | Venous Leg Ulcer | Autologous Adipose Stromal Vascular Fraction | Adipose-Derived Mesenchymal Stem Cells

Hungary
University Hospital, Basel, Switzerland

Recruiting

Patients' Attitudes Towards Open-Label Placebo Implementation Into Clinical Practice (PATOLP)

Open-label Placebos

Switzerland
National University Hospital, Singapore

Not yet recruiting

Splint Versus Steroid Randomized Trial

De Quervain Syndrome
Imam Abdulrahman Bin Faisal University

Not yet recruiting

Minimal Effective Concentration of Lidocaine in Propofol Lidocaine Mixture for Relief of Pain on Propofol Injection

Pain
Servier Bio-Innovation LLC
Institut de Recherches Internationales Servier

Recruiting

A Study of PRS-344/S095012 (PD-L1x4-1BB Bispecific Antibody-Anticalin Fusion) in Patients With Solid Tumors

Solid Tumor

Spain, Australia, Belgium, United States

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