Search clinical trials for: lysosomal storage diseases

Total 376914 results

Triangle Pharmaceuticals

Unknown

A Safety Study to Evaluate 12 Weeks of Treatment with Clevudine in Patients Infected with Hepatitis B Virus.

Hepatitis B

United States, Canada, China, France, Singapore
Argus Pharmaceuticals

Completed

A Study of Nystatin in HIV-Infected Patients

HIV Infections

United States
The Avicena Group

Unknown

Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS)

United States
Eunice Kennedy Shriver National Institute of Child...
Johns Hopkins University

Completed

Study of the Pathogenesis of Rett Syndrome

Rett Syndrome
The Immune Response Corporation

Completed

An Expanded Access Open Label Protocol of Remune (HIV-1 Immunogen) in HIV-1-Infected Adults With CD4 Count 550 Cells /Ml and Greater.

HIV Infections

United States
Chugai Pharma USA

Completed

A Blinded Study Conducted at Multiple Centers Evaluating Various Doses of an Investigational Agent (BO-653) Against Placebo, for Safety and Effectiveness in Preventing Post-Angioplasty Blood Vessel Re-Closure (Restenosis) in Stented Vessels.

Atherosclerosis | Coronary Restenosis | Graft Occlusion, Vascular

United States
GlaxoSmithKline

Unknown

Safety and Effectiveness of TRIZIVIR (Abacavir/Lamivudine/Zidovudine) With Efavirenz in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
National Eye Institute (NEI)

Unknown

The Early Treatment for Retinopathy of Prematurity Study (ETROP)

Retinopathy of Prematurity

United States
National Eye Institute (NEI)

Unknown

The Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study

Myopia

United States
Hoffmann-La Roche

Completed

A Study of Saquinavir and Zalcitabine, Used Alone and Together, in the Treatment of Advanced HIV Infection in Patients Who Stopped Taking or Who Cannot Take Zidovudine

HIV Infections

United States, Puerto Rico, Canada
Ortho Pharmaceuticals

Completed

The Safety and Effectiveness of r-HuEPO in Patients With AIDS or Advanced AIDS-Related Complex (ARC) Who Are Anemic

HIV Infections | Cytopenias

United States
Hoechst Marion Roussel

Completed

A Randomized, Double-Blind Active-Controlled, Dose-Ranging Study of the Safety and Efficacy of Chronically Administered MDL 28,574A in the Treatment of HIV-Infected Patients

HIV Infections

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

International Programs Collaborative Studies Coordinating Center

Heart Diseases | Cardiovascular Diseases | Lung Diseases
Gilead Sciences

Completed

Phase I Study of the Safety, Tolerance, and Pharmacokinetics of 9-[2-(Bispivaloyloxymethyl)Phosphonylmethoxyethyl]Adenine (Bis-POM PMEA; Adefovir Dipivoxil) in HIV-Infected Patients

HIV Infections

United States
National Center for Research Resources (NCRR)

Completed

Body Water Content in Cyanotic Congenital Heart Disease

Heart Defects, Congenital

United States
National Institute of Allergy and Infectious Diseases...

Completed

A "Pre-Enrollment" Protocol for HIV-Infected Adolescents

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

The Effects of Illnesses on HIV Levels in the Body

HIV Infections

United States
Shaman Pharmaceuticals

Completed

Double-Blind Placebo-Controlled Study Comparing the Combination of 15% SP-303 Gel With Acyclovir Versus Acyclovir Alone for the Treatment of Recurrent Herpes Simplex Virus (HSV) Infections in Subjects With Acquired Immunodeficiency Syndrome (AIDS)

HIV Infections | Herpes Simplex

United States, Puerto Rico
Sandoz

Completed

A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With Cytopenia

HIV Infections | Cytopenias

United States
Immunobiology Research Institute

Completed

The Effects of Thymopentin on HIV Infectivity of Blood Cells and Semen in HIV-Infected Patients

HIV Infections

United States
Cytran

Completed

Safety and Effectiveness of an Experimental Drug, IM862, in Treating Kaposi's Sarcoma in AIDS Patients

HIV Infections | Sarcoma, Kaposi

Canada, United States, Australia, Belgium
National Center for Research Resources (NCRR)
Baylor College of Medicine

Completed

Phase IV Study of Chronic Infusional Epoprostenol for Severe Primary Pulmonary Hypertension

Hypertension, Pulmonary
National Center for Research Resources (NCRR)
University of Texas

Completed

Study of Nutritional Factors in Porphyria

Porphyria
National Center for Research Resources (NCRR)

Suspended

A Multi-Centered Study of the Long-Term Effect of Salmeterol and Albuterol in Cystic Fibrosis

Cystic Fibrosis

United States
University of Minnesota

Completed

Phase I/II Study of Total Body Irradiation, Cyclophosphamide, and Fludarabine Followed by Alternate Donor Hematopoietic Cell Transplantation in Patients With Fanconi's Anemia

Fanconi's Anemia

United States
National Center for Research Resources (NCRR)
University of Alabama at Birmingham

Completed

Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Limited to Skin, Eyes, and Mouth

Herpes Simplex

United States, Canada
National Center for Research Resources (NCRR)
Duke University

Unknown

A Safety and Feasibility Study of Active Immunotherapy in Patients With Metastatic Prostate Carcinoma Using Autologous Dendritic Cells Pulsed With Antigen Encoded in Amplified Autologous Tumor RNA

Prostate Cancer

United States
National Center for Research Resources (NCRR)
Crohn's and Colitis Foundation

Completed

A Pharmacokinetic Study to Determine the Oral Bioavailability of Methotrexate in Patients With Inflammatory Bowel Disease

Inflammatory Bowel Disease

United States
National Institute of Allergy and Infectious Diseases...

Completed

Treatment of Acute HIV Infection to Preserve Immune Function

HIV Infections

United States
National Center for Research Resources (NCRR)
National Institute of Neurological Disorders and Stroke (NINDS); University...

Completed

Phase III Randomized, Double-Blind Study of Prednisone for Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy
Gilead Sciences

Unknown

Tenofovir Disoproxil Fumarate in HIV-Infected Patients Who Have Not Had Success With Other Anti-HIV Drug Combinations

HIV Infections

United States
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase I/II Study of High-Dose Acyclovir for Central Nervous System or Disseminated Neonatal Herpes Simplex Virus Infection

Herpes Simplex
National Center for Research Resources (NCRR)
Johns Hopkins University

Completed

Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders

Amino Acid Metabolism, Inborn Errors
Orphan Medical

Completed

Safety and Efficacy of Xyrem Oral Solution (Sodium Oxybate) Compared With Placebo in Narcoleptic Patients

Narcolepsy

United States, Canada, Switzerland
National Eye Institute (NEI)

Completed

Diabetic Retinopathy Vitrectomy Study (DRVS)

Diabetic Retinopathy | Vitreous Hemorrhage | Retinal Detachment
National Eye Institute (NEI)

Unknown

Randomized Trials of Vitamin Supplements and Eye Disease

Macular Degeneration | Cataract
National Institute of Allergy and Infectious Diseases...
Janssen Pharmaceuticals

Completed

A Study of Letrazuril in the Treatment of AIDS-Related Diarrhea

HIV Infections | Cryptosporidiosis

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

A Third-Party Blinded, Placebo Controlled Comparative Study of AS-101 Administered Intravenously in HIV Positive Patients With Advanced Disease

HIV Infections

Brazil
Ionis Pharmaceuticals, Inc.

Completed

A Randomized Comparison of Intravitreal ISIS 2922 Plus Ganciclovir Versus Ganciclovir as Treatment for Patients With Cytomegalovirus Retinitis ( CMVR )

HIV Infections | Cytomegalovirus Retinitis

United States
Gilead Sciences

Completed

An Open-Label Study of the Safety and Efficacy of Cidofovir for the Treatment of Relapsing Cytomegalovirus Retinitis in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
National Center for Research Resources (NCRR)
Yale University

Completed

Developmental Phenomenology of Obsessive Compulsive Disorder and Tourette Syndrome in Children and Adolescents

Obsessive Compulsive Disorder | Tourette Syndrome

United States
Hoechst Marion Roussel

Completed

A Study of MDL 28,574A in HIV-Infected Patients

HIV Infections

United States
Schering-Plough

Completed

A Comparison of SCH 56592 and Fluconazole in the Treatment of Oropharyngeal Candidiasis (OPC) in HIV-Positive Patients

HIV Infections | Candidiasis, Oral

United States, Canada, Chile, Germany, France, Argentina, Belgium, Dominican Republic, Ethiopia, Guatemala, Honduras, Israel, Mexico, Panama, South Africa, Spain, Thailand, Venezuela
National Center for Research Resources (NCRR)
University of Rochester

Completed

Pilot Compassionate Use Study of Thioctic Acid Treatment in Mitochondrial Myopathy

Mitochondrial Myopathy
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Ohio...

Completed

Study of Genetic Anomalies of Complement Related Proteins in Patients With IgA Glomerulonephritis

IGA Glomerulonephritis

United States
National Center for Research Resources (NCRR)
American Heart Association

Completed

Major Depression and Inflammatory Risk Markers for Coronary Heart Disease

Depression

United States
Glaxo Wellcome

Completed

A Study of Amprenavir in HIV-Infected Patients

HIV Infections

United States
Light Sciences LLC

Completed

Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors

Sarcoma | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Rectal Cancer | Pelvic Cancer | Mouth Cancer | Liver Metastasis

United States
R W Johnson Pharmaceutical Research Institute

Completed

A Double-Blind Study to Evaluate the Safety and Pharmacokinetics of L-Ofloxacin (RWJ 25213) in Subjects With HIV Infection

HIV Infections

United States
Immune Enhancement Project

Completed

Acupuncture and Herbal Treatment of Chronic HIV Sinusitis

HIV Infections | Sinusitis

United States

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