Search clinical trials for: Imatinib-Resistant Gastrointestinal Stromal Tumors

Total 56664 results

Pfizer

Not yet recruiting

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Carcinoma, Pancreatic Ductal

Puerto Rico
Revolution Medicines, Inc.

Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Colorectal Cancer | Pancreatic Ductal Adenocarcinoma | Gastrointestinal Cancer | CRC | Metastatic Pancreatic Ductal Adenocarcinoma | PDAC

United States
ITM Solucin GmbH

Not yet recruiting

Phase I Trial to Determine the Dose and Evaluate the PK of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors (KinLET)

Lymphoma | CNS Tumor | Solid Tumor, Childhood | Somatostatin Receptor Positive | NET
BeiGene

Not yet recruiting

A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab, in Participants With Advanced or Metastatic Solid Tumors

Metastatic Solid Tumor | Advanced Hepatocellular Carcinoma | Metastatic Hepatocellular Carcinoma | Alpha-fetoprotein (AFP)-Producing Gastric Cancer | Extragonadal Yolk Sac Tumors | Glypican-3 (GPC3)-Positive Squamous Non-small Cell Lung Cancer
National Cancer Institute (NCI)

Not yet recruiting

Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy

Pheochromocytoma | Somatostatin Receptor Positive | Paragangliomas | Gastrointestinal Neuroendocrine Tumors

United States
Pravin T.P Kaumaya

Not yet recruiting

Vaccine Therapy in Treating Patients With Metastatic Solid Tumors

Metastatic Breast Cancer | HER2-positive Breast Cancer | HER2-positive Gastric Cancer | Metastatic Gastrointestinal Carcinoma | EGFR Overexpression

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Recruiting

A Study of LY4170156 in Participants With Selected Advanced Solid Tumors

Uterine Cervical Neoplasms | Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Ovarian Neoplasms | Endometrial Neoplasms | Triple Negative Breast Neoplasms | Pancreatic Neoplasm

United States
Sykehuset Telemark
Vestre Viken Hospital Trust; Oslo University Hospital; University Hospital of... and other collaborators

Not yet recruiting

Palliative Radiotherapy in Symptomatic Pelvic Soft Tissue Tumors (PALLSOFT)

Gynecologic Cancer | Gastrointestinal Cancer | Urologic Cancer
Shanghai Juncell Therapeutics

Recruiting

Engineering Tumor Infiltrating Lymphocytes Injection (GC203 TIL) for the Treatment of Advanced Malignant Solid Tumors (KUNLUN-001)

Breast Cancer | Gynecologic Cancer | Lung Cancer | Solid Tumor | Gastrointestinal Cancer

China
National Cancer Institute (NCI)

Not yet recruiting

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors

Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage... and other conditions
Cook Research Incorporated

Not yet recruiting

EchoTip AcuCore Post-Market Clinical Study

Adenocarcinoma | Hepatocellular Carcinoma | Neuroendocrine Tumors | Cholangiocarcinoma | Metastasis | Chronic Pancreatitis | Autoimmune Pancreatitis | Malignant Lymphoma
Corregene Biotechnology Co., Ltd

Not yet recruiting

CRTE7A2-01 TCR-T Cells for HPV-16 Positive Advanced Cancers

Cervical Cancer | Anal Cancer | Head and Neck Cancers | Other Solid Tumors
Mayo Clinic

Recruiting

Predicting Response to Immune Checkpoint Inhibitors Across Solid Tumors Using a Live Tumor Diagnostic Platform (CYBRID-04)

Metastatic Lung Non-Small Cell Carcinoma | Metastatic Clear Cell Renal Cell Carcinoma | Resectable Lung Non-Small Cell Carcinoma | Metastatic Malignant Solid Neoplasm | Metastatic Bladder Urothelial Carcinoma | Metastatic Colorectal Carcinoma | Metastatic Triple-Negative Breast Carcinoma | Locally... and other conditions

United States
Australasian Gastro-Intestinal Trials Group
Canadian Cancer Trials Group

Not yet recruiting

Cessation of Somatostatin Analogues After PRRT in Mid, Hind-Gut and Pancreatic Neuroendocrine Tumours (STOPNET)

Neuroendocrine Tumors

Australia
Jonsson Comprehensive Cancer Center

Not yet recruiting

A Vaccine (Neoantigen-Targeted ppDC) for the Treatment of H3 G34-mutant Diffuse Hemispheric Glioma

Diffuse Hemispheric Glioma, H3 G34-Mutant

United States
European Institute of Oncology

Recruiting

YOUNg Adults With Gastro-inteSTinal (GI) and nEuroendocrine canceRs. (YOUNGSTER)

Adenocarcinoma | Neuroendocrine Neoplasm

Italy
Institut Curie
Merck Sharp & Dohme LLC; ProLynx LLC

Not yet recruiting

A Study on Tuvusertib (Oral ATR Inhibitor) in Combination With PLX038 (Topo1 Inhibitor) in Patients With Advanced Solid Tumors (POP-ART)

Solid Tumor

France
Jianjun Yang,MD

Recruiting

Research on the Correlation Between Organoid Drug Sensitivity Testing and Precise Treatment of Gastrointestinal Tumors

Gastrointestinal Tumors，3D Organoids，Drug Sensitivity

China
Enliven Therapeutics

Recruiting

ELVN-002 With Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer

Colorectal Cancer | HER2-positive Breast Cancer | HER2-positive Gastric Cancer | HER2 Amplification | HER2 Positive Solid Tumors

United States
Fondazione del Piemonte per l'Oncologia

Recruiting

SUNNYDAY: SUbepithelialgastroiNtestiNal Tumors Detection,accuracYDiAgnosis,ElastographY and Contrast-enhanced EUS (SunnyDay021)

Subepithelial Gastrointestinal Tumors

Italy
Qilu Hospital of Shandong University

Not yet recruiting

A Real-world Study of Octreotide Microspheres in Chinese Patients With Neuroendocrine Tumors

Neuroendocrine Tumors

China
Nanjing First Hospital, Nanjing Medical University

Recruiting

Endostar Combined With SBRT and Envafolimab in the Treatment of Advanced Gastrointestinal Tumors

Gastrointestinal Neoplasms

China
Pfizer

Recruiting

A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors

Melanoma | Neoplasms | Renal Cell Carcinoma | Non-small-cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Urothelial Carcinoma | Colorectal Carcinoma | Ovarian Carcinoma

United States, Japan, Puerto Rico
West China Hospital

Recruiting

Lactobacillus Reuteri Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors

Oral Mucositis (Ulcerative) Due to Radiation

China
Duke University

Not yet recruiting

Biobanking Upper Gastrointestinal Tumors to Evaluate Response (BURGER With BACON)

GastroEsophageal Cancer

United States
Bavarian Cancer Registry
Bavarian Association of Statutory Health Insurance Accredited Physicians

Not yet recruiting

Risk Factors for Neuroendocrine Neoplasms

Neuroendocrine Neoplasm of Lung | Neuroendocrine Neoplasm of Gastrointestinal Tract (Disorder)
HRYZ Biotech Co.

Not yet recruiting

MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma

Leiomyosarcoma | Fibrosarcoma | Liposarcoma | Angiosarcoma | Synovial Sarcoma | Endometrial Stromal Sarcoma | Undifferentiated Pleomorphic Sarcoma | Epithelioid Sarcoma | Desmoplastic Small Round Cell Tumor | Malignant Peripheral Nerve Sheath Tumors | Pleomorphic Rhabdomyosarcoma

China
AstraZeneca
Daiichi Sankyo Co., Ltd.

Recruiting

A Study of T-DXd in Patients With Selected HER2-overexpressing Tumors

Advanced Solid Tumors (Excluding Gastric Cancer and Breast Cancer)

China
Mayo Clinic

Recruiting

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Malignant Solid Neoplasm | Renal Cell Carcinoma | Hepatocellular Carcinoma | Metastatic Cutaneous Melanoma | Unresectable Cutaneous Melanoma | Lung Non-Small Cell Carcinoma | Urothelial Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Recurrent Head and Neck Squamous... and other conditions

United States
NiKang Therapeutics, Inc.

Recruiting

A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors

Small Cell Lung Carcinoma | Gastric Cancer | Ovarian Neoplasms | Ovarian Cancer | Solid Tumor | Endometrial Neoplasms | Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Advanced Solid Tumor | Endometrial Cancer | Small-cell Lung Cancer | Platinum-resistant Ovarian Cancer | Ovarian Carcinoma | Solid... and other conditions

United States
Fudan University
Changhai Hospital; Shanghai East Hospital; Shanghai Changzheng Hospital

Not yet recruiting

Wound Management Following Gl Tumor Surgery: Comparing Outcomes of Dressing Changes Versus Non-Dressing Techniques (Dressing)

Pain, Postoperative | Surgical Wound Infection | Gastrointestinal Tumors

China
Case Comprehensive Cancer Center

Not yet recruiting

EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.

Stomach Cancer | Esophageal Cancer | Rectal Cancer | Neuroendocrine Tumors | Colon Cancer | Pancreas Cancer | Gastrointestinal Cancer | Anal Cancer | Liver Cancer | Appendix Cancer

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Multi-modal Characterisation of Gastroenteropancreatic Neuroendocrine Tumours (GEP-NETs) Treated With Targeted Radionuclide Therapy (TRT): Prospective Interventional Multicentre National Cohort (OPERANDI-NET)

Radiotherapy | Gastroenteropancreatic Neuroendocrine Tumor

France
BeiGene

Recruiting

A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors

Breast Cancer | Small Cell Lung Cancer | Gastric Cancer | Ovarian Cancer | Prostate Cancer | Advanced Solid Tumor | Endometrial Cancer | Hormone Receptor Positive HER-2 Negative Breast Cancer | Hormone-receptor-positive Breast Cancer

United States, Australia
Ipsen

Recruiting

A Study to Understand Participant's Experiences in Gastro-enteropancreatic Neuroendocrine Tumors (GEP-NETs) and Acromegaly (BackSOM)

Acromegaly | Gastro-enteropancreatic Neuroendocrine Tumor

United States
West China Hospital

Not yet recruiting

A Lithium-containing Mouthwash Prevention and Treatment of Oral Mucositis and Dysgeusia in Patients Undergoing Radiotherapy

Head and Neck Squamous Cell Carcinoma | Malignant Head and Neck Tumors

China
Jagiellonian University
University Hospital in Krakow

Recruiting

Clinical Application of the J-PET Scanner Prototype (JPET2Clinic)

Prostatic Neoplasms | Prostatic Hyperplasia | Prostate Cancer | Neuroendocrine Tumors | Neuroendocrine Carcinoma | Prostate Cancer Metastatic

Poland
Merck Sharp & Dohme LLC

Recruiting

Safety and Efficacy of MK-1200 in Participants With Advanced Solid Tumors

Advanced Solid Tumors

Israel, United States, Australia, Chile
Beijing 302 Hospital

Recruiting

Application of Multimodal Endoscopic Functional Imaging Technology in the Diagnosis of Common Gastrointestinal Diseases (Endo-mmfi)

Gastrointestinal Disease

China
Centre Hospitalier Universitaire de Nīmes

Not yet recruiting

Safety & Efficacy of Ischemic Preconditioning by Embolization of the Inferior Mesenteric Artery in Surgery for Tumors of Lower and Middle Rectum (AMIREMBOL_2)

Cancer, Rectal
Seoul National University Hospital
Samsung Medical Center; Asan Medical Center; Chonnam National University Hospital and other collaborators

Recruiting

Development of Clinical Evidence for Optimal Management of Adrenal Diseases Based on Real-World Data

Primary Aldosteronism | Cushing Syndrome | Pheochromocytoma | Adrenal Cortical Carcinoma | Adrenal Tumor

Korea, Republic of
N.N. Petrov National Medical Research Center of...

Recruiting

Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS Mutations (NТО-RAS)

Melanoma | Lung Cancer | Pancreas Cancer | Refractory Cancer | Colorectal Cancer Recurrent | RAS Mutation | Ras (Kras or Nras) Gene Mutation

Russian Federation
Renmin Hospital of Wuhan University

Recruiting

Nutritional Psychological Intervention and Vomit-free Management on Survival and Quality of Life in Advanced Gastrointestinal Tumors

Digestive System Neoplasm | Digestive System Cancer

China
Jonsson Comprehensive Cancer Center

Not yet recruiting

Fluoxetine for the Modification of Colorectal Tumor Immune Cells Before Surgery in Patients With Colorectal Cancer

Colorectal Adenocarcinoma

United States
Southern Medical University, China

Not yet recruiting

The Effectiveness of HP and TMZ Synergism on Adult Recurrence GBM

Glioblastoma Multiforme
Neogene Therapeutics, Inc.

Recruiting

A Study of NT-112 in HLA-C*08:02-Positive Adult Subjects With Unresectable, Advanced, and/ or Metastatic Solid Tumors Positive for the KRAS G12D Mutation

Endometrial Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma | Colorectal Carcinoma | Solid Tumor, Adult | KRAS G12D

United States
Radboud University Medical Center

Not yet recruiting

PRE- MISTIC: MRI and Cine Imaging to Improve Staging of Tumors In the Colon (PRE-MISTIC)

Colon Cancer

Netherlands
University Hospital, Essen

Recruiting

Prospective Validation of Adaptive Radiotherapy (ART) in Patients With Head and Neck Tumors (ART in HNT)

Head and Neck Cancer | Optimized Treatment | Radiation | Adaptive Radiotherapy | Protection of Organs at Risk | Dysphagia Reduction

Germany
University of Aarhus

Recruiting

FMT in Checkpoint Inhibitor-mediated Diarrhea and Colitis (Immunobiome)

Kidney Cancer | Diarrhea | Colitis | Malignant Melanoma

Denmark
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Prospective Single-center Study About the Use of ctDNA in the Management of Patients With Tumors of the Gastrointestinal Tract (ctDNA-GI)

Colon Cancer | Pancreas Cancer | Biliary Tract Cancer

Italy

Search clinical trials for: Imatinib-Resistant Gastrointestinal Stromal Tumors

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