Search clinical trials for: mRNA

Total 591 results

RVAC Medicines (US), Inc.

Terminated

Safety and Immunogenicity of RVM-V001 in Healthy Individuals Previously Vaccinated With BNT162b2 and mRNA-1273

COVID-19 | Infectious Disease

Australia
CanSino Biologics Inc.

Withdrawn

A Study to Evaluate the Safety and Immunogenicity of Ad5-vector Based Vaccine Against Coronavirus Variants in Adults (≥18 Years) Immunized With 2 Doses of mRNA Vaccines Plus One Dose of Booster AZD1222 Vaccine

COVID-19
Beijing 302 Hospital

Active, not recruiting

Autologous T-cells Transfected With mRNA Encoding HBV-TCR T Cell Therapy in Combination With NUC for Chronic Hepatitis B

Chronic Hepatitis B

China
ModernaTX, Inc.

Active, not recruiting

Moderna Vaccine mRNA-1345 Observational Respiratory Syncytial Virus (RSV) Study

Respiratory Syncytial Virus

United States
Mustafa Khasraw, MBChB, MD, FRCP, FRACP

Completed

DC Migration Study for Newly-Diagnosed GBM (ELEVATE)

Glioblastoma | Glioblastoma Multiforme | Giant Cell Glioblastoma | Astrocytoma, Grade IV

United States
Centre Hospitalier Universitaire de Saint Etienne
Sanofi Pasteur, a Sanofi Company; Bioster, a.s.

Completed

Factors Influencing the COVID-19 Vaccine Immune Response According to Age and Presence or Not of a Past History of COVID-19 (COVIMMUNAGE)

Covid19

France
Valneva Austria GmbH

Completed

VLA2001 Booster in Adult Participants After Priming With mRNA COVID-19 Vaccine and/or Natural SARS-CoV-2 Infection

SARS-CoV-2 Infection

New Zealand, Netherlands
Pfizer

Completed

This Study Intends to Describe the Characteristics of Patients Given the Pfizer-BioNTech Bivalent mRNA COVID-19 Vaccine and Any Commercially Available Influenza Vaccines at the Same Time Versus at Different Times.

COVID-19 | Influenza, Human

United States
Quratis Inc.

Active, not recruiting

Study to Assess Safety, Reactogenicity and Immunogenicity of the repRNA(QTP104) Vaccine Against SARS-CoV-2(COVID-19)

COVID-19 | SARS-CoV-2

Korea, Republic of
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Active, not recruiting

A Study of SARS-CoV-2 mRNA Vaccine (SYS6006) in Chinese Healthy Adults Aged 18 -59 Years.

SARS-CoV-2

China
National Institute of Allergy and Infectious Diseases...

Completed

SARS-CoV-2 Immune Responses After COVID-19 Therapy and Subsequent Vaccine

Covid19 | SARS-CoV2 Infection

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Active, not recruiting

A Study of SARS-CoV-2 mRNA Vaccine (SYS6006) in Chinese Healthy Participants Aged 18 Years or More

SARS-CoV-2 Infection

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Active, not recruiting

A Study of SARS-CoV-2 mRNA Vaccine (SYS6006) in Chinese Healthy Older Adults.

SARS-CoV-2

China
Indiana University

Terminated

Immune Responses in Oncology Patients to Novel Coronavirus Vaccines (IROC)

Cancer

United States
ModernaTX, Inc.

Active, not recruiting

A Study of mRNA-1011.1, mRNA-1011.2, and mRNA-1012.1 Candidate Seasonal Influenza Vaccines in Healthy Adults

Seasonal Influenza

United States
ModernaTX, Inc.

Completed

Long-Term Follow-up Survey of COVID-19 Vaccine After Vaccination

Coronavirus Disease (COVID-19)

Japan
University of Melbourne
Southern Star Research Pty Ltd.

Completed

Safety and Immune Response of Adjuvanted SARS-CoV-2 (COVID-19) Beta Variant RBD Recombinant Protein (DoCo-Pro-RBD-1 + MF59®) and mRNA (MIPSCo-mRNA-RBD-1) Vaccines in Healthy Adults

SARS-CoV-2

Australia
Oslo University Hospital

Completed

Trial of Vaccine Therapy With mRNA- Transfected Dendritic Cells in Patients With Androgen Resistant Metastatic Prostate Cancer

Prostate Cancer

Norway
Sunnybrook Health Sciences Centre
University Health Network, Toronto; Unity Health Toronto; Scarborough General... and other collaborators

Terminated

COVID-19 Vaccine Boosters in Patients With CKD (BOOST KIDNEY)

COVID-19 | Chronic Kidney Diseases

Canada
Wuhan Recogen Biotechnology Co., Ltd.

Withdrawn

Safety, Reactogenicity, and Immunogenicity Study of a Lyophilized COVID-19 mRNA Vaccine

COVID-19 Pandemic
H. Lee Moffitt Cancer Center and Research Institute
ModernaTX, Inc.

Completed

COVID-19 Immunogenicity of a Third Dose of mRNA-1273 Vaccine Among Cancer Patients

Covid19 | SARS-CoV2 Infection

United States
Seoul National University Bundang Hospital

Completed

Long-term Follow-up of Interleukin-1B and H+,K+-ATPase mRNA Expression After Helicobacter Pylori Eradication

Helicobacter Pylori Infection

Korea, Republic of
GlaxoSmithKline
CureVac

Completed

Safety, Reactogenicity, and Immunogenicity Trial of CV2CoV mRNA Vaccine Against SARS-CoV-2 in Seropositive Adult Participants

SARS-CoV-2

United States
Providence Therapeutics Holdings Inc.

Completed

PTX-COVID19-B, an mRNA Humoral Vaccine, Intended for Prevention of COVID-19 in a General Population. This Study is Designed to Demonstrate the Safety, Tolerability, and Immunogenicity of PTX-COVID19-B in Comparison to the Pfizer-BioNTech COVID-19 Vaccine.

Covid19 Vaccine

Canada, South Africa
ModernaTX, Inc.

Completed

Use of Wearable Digital Sensors After mRNA Vaccination in Adults

Healthy Participants

United States
Providence Health & Services

Terminated

Efficacy of COVID-19 Vaccination in Patients With Multiple Sclerosis Treated With Immune Modulating Medication

Multiple Sclerosis

United States
Norwegian School of Sport Sciences
King's College London; Oslo University Hospital; Rigshospitalet, Denmark; University... and other collaborators

Terminated

Androgen Deprivation Therapy Muscle Protein Metabolism and Blood Glucose

Prostate Cancer | Resistance Exercise | Androgen Deprivation Therapy

Norway
Medigen Vaccine Biologics Corp.
Coalition for Epidemic Preparedness Innovations

Completed

A Study to Evaluate the Safety and Immunogenicity of Booster With AZD1222, mRNA-1273, or MVC-COV1901 Against COVID-19

COVID-19 Vaccine

Taiwan
LTN PHARMACEUTICALS, INC.

Terminated

A Study of Galeterone Compared to Enzalutamide In Men Expressing Androgen Receptor Splice Variant-7 mRNA (AR-V7) Metastatic CRPC (ARMOR3-SV)

Prostate Cancer

United States, France, Australia, Canada, Spain, United Kingdom, Italy, Belgium
International AIDS Vaccine Initiative
ModernaTX, Inc.; AURUM Tembisa Clinical Research; Center for Family Health Research

Active, not recruiting

A Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644)

HIV-1-infection

Rwanda, South Africa
Eunice Kennedy Shriver National Institute of Child...

Completed

Microarray Expression Profiling to Identify Stereotypic mRNA Profiles in Human Parturition

Preterm Birth | Premature Rupture of Membranes

United States, Korea, Republic of, Chile, Italy
Maria Joyera Rodríguez

Withdrawn

Study About the Response to the Administration of a Third Dose of mRNA-1273 Vaccine (COVID-19 Vaccine Moderna) in Renal Transplants With Immunological Failure Initial to Vaccination (VAX-TRES)

Covid19
Erasmus Medical Center
University Medical Center Groningen; Academisch Medisch Centrum - Universiteit... and other collaborators

Active, not recruiting

SWITCH ON: Analysing the Immunogenicity of Additional Booster Vaccinations in HCW (SWITCHON)

Covid-19 Vaccination

Netherlands
AIM Vaccine Co., Ltd.
First Affiliated Hospital Bengbu Medical College; Ningbo Rongan Biological...

Active, not recruiting

A Cohort Study of COVID-19 mRNA Vaccine, Bivalent in Participants in China

SARS-CoV-2

China
AIM Vaccine Co., Ltd.
First Affiliated Hospital Bengbu Medical College; Ningbo Rongan Biological...

Active, not recruiting

A Preliminary Exploratory Cohort Study of SARS-CoV-2 Variant (Omicron BA.5) mRNA Vaccine in Participants Aged 18 Years and Over in China

SARS-CoV-2

China
AIM Vaccine Co., Ltd.
First Affiliated Hospital Bengbu Medical College; Ningbo Rongan Biological...

Active, not recruiting

A Preliminary Exploratory Cohort Study of COVID-19 mRNA Vaccine, Bivalent in Participants Aged 18 Years and Over in China

SARS-CoV-2

China
Murdoch Childrens Research Institute

Completed

Investigating COVID-19 Vaccine Immunity in Children in the Melbourne Infant Study of BCG for Allergy and Infection Reduction (COSI BAIR)

COVID-19 | Vaccine Reaction | Immunization; Infection

Australia
Chulalongkorn University
National Vaccine Institute, Thailand; Chula Vaccine Research Center (ChulaVRC)... and other collaborators

Completed

ChulaCov19 Vaccine in Healthy Adults

COVID-19 Vaccine | Safety Issues

Thailand
Murdoch Childrens Research Institute
Coalition for Epidemic Preparedness Innovations; The Peter Doherty Institute...

Completed

Evaluation of Full Versus Fractional Doses of COVID-19 Vaccines Given as a Booster in Adults in Australia - Mongolia, Indonesia, Australia Coronavirus (MIACoV). (MIACoV)

COVID-19

Australia
Suzhou Abogen Biosciences Co., Ltd.

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of SARS-CoV-2 Variant (COVID-19 Omicron) mRNA Vaccine (Phase 1)

COVID-19

United Arab Emirates
Suzhou Abogen Biosciences Co., Ltd.

Active, not recruiting

A Study to Evaluate Safety, Tolerability, and Immunogenicity of SARS-CoV-2 Variant (COVID-19) mRNA Vaccines

COVID-19

Indonesia
Stemirna Therapeutics

Active, not recruiting

mRNA Booster Vaccine(SW-BIC-213) Compared With Pfizer andSinopharm Against Emerging VOCs

Efficacy | Safety | Immunogenicity

Lao People's Democratic Republic
Memorial Sloan Kettering Cancer Center
Rockefeller University

Completed

Immune Responses to Autologous Langerhans-type Dendritic Cells Electroporated With mRNA Encoding a Tumor-associated Antigen in Patients With Malignancy: A Single-arm Phase I Trial in Melanoma

Melanoma

United States
Regeneron Pharmaceuticals

Completed

COVID-19 Study to Assess Immunogenicity, Safety, and Tolerability of Moderna mRNA-1273 Vaccine Administered With Casirivimab+Imdevimab in Healthy Adult Volunteers

Healthy | Chronic Stable Illness

United States
Institut Pasteur de Tunis

Completed

Immunogenicity of Heterologous Versus Homologous Prime Boost Schedule With mRNA and Inactivated COVID-19 Vaccines

COVID-19

Tunisia
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); Samuel Lunenfeld Research Institute... and other collaborators

Active, not recruiting

SafeTy and Efficacy of Preventative CoVID Vaccines (STOPCoV)

Vaccine Response | COVID-19 Virus Infection

Canada
Serge Thal

Completed

Effect of Different SARS-CoV-2 Vaccine Schedules and Vaccination Intervals on Reactogenicity and Humoral Immunogenicity

SARS-CoV2 Infection | Tolerance | Immunisation Reaction | Antibody Hypersensitivity

Germany
ModernaTX, Inc.
Biomedical Advanced Research and Development Authority

Completed

Dose-Confirmation Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1273 COVID-19 Vaccine in Adults Aged 18 Years and Older

SARS-CoV-2

United States
Harald Wolf, MD
Medical Scientific Fund of the Mayor of Vienna

Completed

The Clinical Relevance of Micro RNAs in Mild Traumatic Brain Injury (mRNA)

Brain Injuries, Traumatic

Austria
Stemirna Therapeutics

Completed

A Phase I/II Clinical Trial in Healthy People Aged 18 Years and Above

COVID-19 Pandemic

Lao People's Democratic Republic

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