Search clinical trials for: Non-Nucleoside Reverse transcriptase Inhibitor

Total 68491 results

Janssen Research & Development, LLC

Completed

A Study in Healthy Participants to Assess the Effect of Darunavir, Emtricitabine, and Tenofovir Alafenamide in the Presence of Cobicistat as Fixed Dose Combination (Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide) Compared With Co-administration of the Separate Agents

Healthy

Netherlands
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy

HIV Infections

United States, Puerto Rico, Thailand, Botswana, Argentina, Brazil, Tanzania, South Africa
Ann & Robert H Lurie Children's Hospital of Chicago
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Study of HIV-Infected and Uninfected Pregnant Woman/Child Dyads in Gaborone, Botswana

Diabetes Mellitus | HIV | Insulin Sensitivity

Botswana
Xiangya Hospital of Central South University

Completed

The Renal Safety of Tenofovir Alafenamide in HBV-related Acute-on-chronic Liver Failure: Real-World Study

Antiviral Drugs

China
Fundación FLS de Lucha Contra el Sida, las Enfermedades...
Institut d'Investigació Biomèdica de Bellvitge; Hospital Universitari de Bellvitge

Completed

Doravirine Concentrations and Antiviral Activity in Genital Fluids in HIV-1 Infected Individuals

HIV-1-infection

Spain
Johnson & Johnson Pte Ltd

Terminated

A Study to Determine the Safety and Efficacy of Rilpivirine in Treatment-naive Indian Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Infection (RISE)

Human Immunodeficiency Virus Infections

India
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of a Moderate CYP3A Inducer Efavirenz on Quizartinib Pharmacokinetics in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Fundacion SEIMC-GESIDA
Janssen-Cilag, S.A.

Completed

A Clinical Trial to Evaluate the Reversibility of Abacavir/Lamivudine/Dolutegravir CNS-Related Neurotoxicity After Switching to Tenofovir/Alafenamide/Emtricitabine/Darunavir/Cobicistat (TAF/FTC/DRV/c) (DETOX)

HIV Infections

Spain
University of Southern Denmark

Terminated

Metformin's Effect on Drug Metabolism in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Denmark
Daewoong Pharmaceutical Co. LTD.
C&R Research, Inc.

Completed

Evaluate the Efficacy and Safety to Tenofovir Disoproxil in Chronic Hepatitis B Patients (HBV)

Hepatitis B, Chronic

Korea, Republic of
Professor Francois Venter
University of Cape Town

Completed

The Effect of Rifampicin on the Pharmacokinetics of Intracellular Tenofovir-diphosphate and Tenofovir When Coadministered With Tenofovir Alafenamide Fumarate During the Maintenance Phase of Tuberculosis Treatment in TB/HIV-1 Coinfected Participants (EpiTAF)

Tuberculosis | HIV-1-infection

South Africa
University of Texas Southwestern Medical Center

Terminated

ARQ-761 Treatment With Gemcitabine/Nab-Paclitaxel Chemotherapy In Pancreatic Cancer

Pancreatic Cancer

United States
Wuhan Union Hospital, China

Enrolling by invitation

An Experimental Study on the Effect of Tenofovir Amibufenamide on Blood Lipid During Anti-HBV Treatment

Hepatitis B, Chronic | Lipid Disorder

China
Antios Therapeutics, Inc

Terminated

A Study of Safety and Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infection

Chronic Hepatitis b

Moldova, Republic of, Ukraine
University College Dublin
Rush University Medical Center; Royal College of Surgeons, Ireland; Mater Misericordiae... and other collaborators

Terminated

Alendronate for Prevention of AntiRetroviral Therapy-associated Bone Loss (APART)

Bone Demineralization

Ireland
Sunshine Lake Pharma Co., Ltd.

Completed

GLS4/RTV and TAF Drug-drug Interaction

Chronic Hepatitis B

China
West China Hospital

Active, not recruiting

RCT of Different Effects of Nucleot(s)Ide Analogues on the Prognosis of HBV-HCC Patients After Curative Resection

HCC | HBV Coinfection

China
University of Chicago
Planned Parenthood Great Plains

Withdrawn

Accelerated PrEP Access for Black MSM and TW

HIV/AIDS
Institut Bergonié

Completed

Efavirenz in Treating Patients With Metastatic Prostate Cancer (FAVE)

Prostate Cancer

France
Centers for Disease Control and Prevention
Botswana Ministry of Health

Completed

Open Label Extension (OLE) of the TDF2 Study, Botswana (TDF2-OLE)

HIV Infections
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

The Incidence of Hepatitis B Reactivations in Patients Affected by Chronic Lymphocytic Leukemia With Ibrutinib (LLC1618)

Chronic Lymphocytic Leukemia

Italy
University of Liege

Active, not recruiting

Impact of DOlutegravir+Lamivudine Simplification on HIV-1 Reservoirs (IDOLTIB)

HIV Infections

Belgium
National Institute of Allergy and Infectious Diseases...

Completed

Pharmacokinetic and Safety Study of a 90 Day Intravaginal Ring Containing Tenofovir

HIV Infections

United States
Mylan (Taiwan) Ltd

Completed

Efficacy and Safety of Ricovir® in Maintaining Durability of Viral Response in Chronic Hepatitis B Patients Who Have Been Treated With Viread® and Have Undetectable HBV DNA in Serum

Chronic Hepatitis B Infection

Taiwan
Fundación FLS de Lucha Contra el Sida, las Enfermedades...
Institut d'Investigació Biomèdica de Bellvitge; Hospital Universitari de Bellvitge

Completed

Doravirine Concentrations and Antiviral Activity in Cerebrospinal Fluid in HIV-1 Infected Individuals

HIV-1-infection

Spain
Kenneth H. Mayer, MD
Gilead Sciences

Completed

HIV Non-Occupational Post-Exposure Prophylaxis (QUAD)

Human Immunodeficiency Virus

United States
Pedro Cahn
ViiV Healthcare

Withdrawn

Dolutegravir-Lamivudine as Dual Therapy in naïve HIV-Infected Patients With Documented M184V Mutation:A Pilot Study (PADDLE184V)

HIV-1 Infection

Argentina
Fenway Community Health

Completed

Biktarvy for Non-Occupational Post-Exposure Prophylaxis (nPEP)

HIV Prevention

United States
Johns Hopkins University

Withdrawn

Pre-Exposure Prophylaxis Dosing in Pregnancy to Optimize HIV Prevention (PREP-P)

Pregnancy | HIV-1-infection
Samjin Pharmaceutical Co., Ltd.

Completed

A phase4 Clinical Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Disoproxil From Tenofovir Disoproxil Fumarate in Patients With Chronic Hepatitis B

Chronic Hepatitis B

Korea, Republic of
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France; Centre Muraz

Active, not recruiting

Preventing Childhood HIV: Rescue Intervention. ANRS 12388 PREVENIR-PEV (PREVENIR-PEV)

HIV-1

Burkina Faso
Mylan Inc.
ViiV Healthcare

Completed

Abacavir, Dolutegravir and Lamivudine Dispersible Tablets (60 mg/5 mg/30 mg)

HIV-1-infection

Canada
Sabyasachi Sen

Completed

Effect on HIV Medications on EPC Cells

AIDS

United States
Samjin Pharmaceutical Co., Ltd.

Completed

Clinical Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Disoproxil From Tenofovir Disoproxil Fumarate in Patients With Chronic Hepatitis B

Chronic Hepatitis b

Korea, Republic of
Myanmar Oxford Clinical Research Unit
Institute of Tropical Medicine, Belgium; Medical Action Myanmar

Completed

PrEP Among MSM and TG in Myanmar (PrEP)

HIV Infections

Myanmar
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Alafenamide in Human Immunodeficiency Virus (HIV-1) Infected, Antiretroviral Treatment-Naive Adults

HIV-1 Infection

Spain, United States, Italy, Germany, United Kingdom, France, Australia, Puerto Rico, Canada, Belgium, Dominican Republic
Rhonda Brand
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Development of a Urine-Based Point-of-Care Test for Adherence to Antiretroviral Drugs (APTAMER)

HIV | Medication Adherence

United States
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Abacavir/Dolutegravir/Lamivudine in Human Immunodeficiency Virus-1 (HIV-1) Infected, Antiretroviral Treatment-Naive Adults

HIV-1 Infection

France, Spain, Germany, United Kingdom, United States, Puerto Rico, Belgium, Canada, Italy, Dominican Republic
New York University
University of Nairobi; Impact Research & Development Organization

Completed

Gender-Specific Combination HIV Prevention for Youth in High Burden Settings (MP3-Youth) (MP3-Youth)

HIV | Adolescent Behavior | Gender

United States, Kenya
GlaxoSmithKline

Completed

Efficacy and Safety Study of Tenofovir Disoproxil Fumarate (TDF) in Chinese Chronic Hepatitis B (CHB) Subjects With Advanced Fibrosis & Compensated Cirrhosis

Hepatitis B, Chronic

China
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating Strategies to Reduce Mother-to-Child Transmission of HIV Infection in Resource-Limited Countries (PROMISE)

HIV Infections

Malawi, South Africa, Tanzania, Zimbabwe, India, Uganda, Zambia
Antios Therapeutics, Inc

Completed

A Drug-Drug Interaction Study Between ATI-2173 and Tenofovir Disoproxil Fumarate in Healthy Subjects

Drug Interaction

Canada
Gilead Sciences

Completed

Switching to a Fixed Dose Combination of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Adults Who Are Virologically Suppressed

HIV-1-infection

United States, Puerto Rico, France, Germany, Austria, Canada
University of Southern Denmark
SignaTope GmbH, Germany

Completed

Flucloxacillin as an Inducer of CYP-enzymes

Healthy Volunteers | Drug Drug Interaction

Denmark
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France

Completed

National Multicenter Trial Evaluating Two Treatments in Patients With Primary Human Immunodeficiency Virus (HIV-1) Infection (OPTIPRIM-2)

HIV-1 Infection

France
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A Drug-drug Interaction Study of SHR2150 on Healthy Chinese Volunteers

Human Immunodeficiency Virus Infection

China
University of Washington
Harvard Medical School (HMS and HSDM); National Institute of Mental Health... and other collaborators

Completed

The Prevention Options for Women Evaluation Research (POWER) Cohort

HIV/AIDS

Kenya, South Africa
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Study of SHR6390 on Healthy Chinese Volunteers

Advanced Solid Tumor

China
University of North Carolina, Chapel Hill
ViiV Healthcare

Completed

Safety and Efficacy of Fixed Dose Combination Dolutegravir/Abacavir/Lamivudine FDC Initiated During Acute HIV Infection (PHI-05)

HIV | Acute HIV Infection

United States
Thomas Jefferson University

Completed

Study Comparing the Safety of Switching From Lamivudine to Adefovir Dipivoxil Versus Overlapping Lamivudine and Adefovir Before Adefovir Dipivoxil Monotherapy in Patients With Chronic Hepatitis B

Chronic Hepatitis B

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