Search clinical trials for: Tocilizumab

Total 514 results

Hoffmann-La Roche

Completed

A Study to Provide RoActemra/Actemra (Tocilzumab) to Patients With Multicentric Castleman's Disease Who Demonstrated Benefit From Previous RoActemra/Actemra Treatment

Castleman's Disease

United States
Hoffmann-La Roche

Completed

An Observational Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis (ACTIVATE)

Rheumatoid Arthritis

Hungary
Hoffmann-La Roche

Completed

An Observational Study of RoActemra/Actemra (Tocilizumab) in Rheumatoid Arthritis Patients

Rheumatoid Arthritis

Greece
Hoffmann-La Roche

Unknown

An Observational Study on Long-Term Effectiveness and Safety of RoActemra/Actemra (Tocilizumab) in Daily Practice in Patients With Rheumatoid Arthritis (ICHIBAN)

Rheumatoid Arthritis

Germany
Hoffmann-La Roche

Completed

A Retrospective Observational Study on Compliance in Patients With Rheumatoid Arthritis on Treatment With RoActemra/Actemra (Tocilizumab) in Clinical Practice (REMISSION II)

Rheumatoid Arthritis

Greece
Hoffmann-La Roche

Completed

A Study to Assess the Safety and Efficacy of Tocilizumab in Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

France, Italy, Spain, United States, Australia, Canada, Mexico, South Africa, Portugal, Slovenia, Serbia, Israel, Lithuania, Argentina, China, Denmark, Norway, Peru
Hoffmann-La Roche

Completed

An Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to DMARDs

Rheumatoid Arthritis

Slovakia
Hoffmann-La Roche

Completed

A Long-Term Extension Study of RoActemra/Actemra (Tocilizumab) in Patients With Juvenile Idiopathic Arthritis From France Who Completed WA19977 Core Study

Juvenile Idiopathic Arthritis

France
Hoffmann-La Roche

Completed

A Study of Administration of RoActemra/Actemra (Tocilizumab) by Auto-injector Vs. Pre-filled Syringe in Healthy Volunteers

Healthy Volunteer

France
University of Zurich
European Foundation for the Study of Diabetes

Completed

Role of Interleukin-6 in Exercise (Exil-6)

Obesity | Diabetes Mellitus, Type 2

Switzerland
Hoffmann-La Roche

Completed

A Prospective Observational Study of Tocilizumab (RoActemra/Actemra) in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

Spain
Hoffmann-La Roche

Completed

An Observational Study of RoActemra/Actemra (Tocilizumab) As Monotherapy in Rheumatoid Arthritis Patients in Routine Clinical Practice (ACT SOLO)

Rheumatoid Arthritis

France
Hoffmann-La Roche

Completed

A Non-Interventional Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Indonesia
Hoffmann-La Roche

Completed

Use of Tocilizumab for Rheumatoid Arthritis (RA) in Daily Routine

Rheumatoid Arthritis

Germany
Hoffmann-La Roche

Terminated

A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Severe Active Rheumatoid Arthritis, Comparing Tapering Versus Maintaining the Methotrexate Dosage

Rheumatoid Arthritis

United Kingdom
Genentech, Inc.

Completed

A Long-Term Extension Study of WA22762 and NA25220 of Subcutaneous (SC) Tocilizumab (TCZ) in Moderate to Severe Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States, Puerto Rico
Hoffmann-La Roche

Completed

A Non-Interventional Study in Rheumatoid Arthritis Patients Treated With Tocilizumab (RoActemra/Actemra)

Rheumatoid Arthritis

Canada
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) Versus Placebo in Patients With Systemic Sclerosis

Sclerosis, Systemic

Germany, United States, France, United Kingdom, Canada
Hoffmann-La Roche

Completed

An Open-Label Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

Australia
Hoffmann-La Roche

Terminated

An Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Romania
University Hospital, Brest

Completed

Lymphocyte and Cytokine Disturbances in Polymyalgia Rheumatica (TENOR-IMMUNO)

Polymyalgia Rheumatica

France
Cedars-Sinai Medical Center

Completed

A Safety Study of Tocilizumab to Improve Transplant Rates in Highly Sensitized Patients Awaiting Kidney Transplantation

End Stage Renal Disease (ESRD)

United States
Maria Stoenoiu

Unknown

Ultrasound as Imaging Biomarker of Early Response to Tocilizumab and Methotrexate in Very Early Rheumatoid Arthritis (TOVERA)

Rheumatoid Arthritis

Belgium
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA)

Juvenile Idiopathic Arthritis

Belgium, Italy, Spain, United States, Greece, Germany, Australia, Brazil, Argentina, Canada, United Kingdom, Poland, Denmark, Norway, Mexico, Slovakia, Sweden, Czech Republic, Netherlands
Hoffmann-La Roche

Completed

Observational Study of Tocilizumab in Participants With Rheumatoid Arthritis in Australia

Rheumatoid Arthritis

Australia
Washington University School of Medicine

Withdrawn

Allogeneic Stem Cell Transplantation for Patients With Multiple Myeloma

Multiple Myeloma | Myeloma-Multiple
Hoffmann-La Roche

Completed

A Study of Tocilizumab and Methotrexate in Combination or as Monotherapy in Treatment-Naïve Patients With Early Rheumatoid Arthritis

Rheumatoid Arthritis

Netherlands
Hoffmann-La Roche

Completed

Efficacy and Safety Study of RoActemra (Tocilizumab) in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

Austria
Hoffmann-La Roche

Completed

A Study to Compare Subcutaneous Versus Intravenous Administration of RoActemra/Actemra (Tocilizumab) in Participants With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

France, Germany, Italy, Spain, United Kingdom, Hong Kong, United States, Colombia, Brazil, Canada, New Zealand, South Africa, Philippines, Russian Federation, Thailand, Singapore, Bulgaria, Mexico, Australia, Lithuania, Poland, Ar... and more
Hoffmann-La Roche

Completed

An Observational Study on RoActemra/Actemra (Tocilizumab) in Clinical Practice in Patients With Rheumatoid Arthritis (TRUST)

Rheumatoid Arthritis

Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Tocilizumab for Chronic Graft-versus-Host Disease Treatment

Graft Versus Host Disease

United States
Hoffmann-La Roche

Completed

An Extension Long-Term Study of RoActemra/Actemra (Tocilizumab) in Patients With Polyarticular Juvenile Idiopathic Arthritis Who Completed The WA19977 Study

Juvenile Idiopathic Arthritis

Brazil
Sanofi
Regeneron Pharmaceuticals

Completed

Single-dose Study to Describe the Safety of Sarilumab and Tocilizumab in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Japan
Hoffmann-La Roche
Clalit Health Services

Completed

Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Israel
Ospedale San Raffaele

Terminated

Pilot Study of Tocilizumab in Patients With Erdheim-Chester Disease

Erdheim-Chester Disease

Italy
Hoffmann-La Roche

Completed

An Global Comparative Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Belgium, Germany, Spain, Colombia, United Kingdom, Greece, Portugal, Switzerland, Italy, Mexico, Argentina, Guatemala, Panama, Ukraine, Ecuador, Uruguay
Hoffmann-La Roche

Completed

A Study to Assess Efficacy With Respect to Clinical Improvement in Disease Activity and Safety of Tocilizumab in Patients Wtih Active Rheumatoid Arthritis.

Rheumatoid Arthritis

Germany
Leiden University Medical Center
University Medical Center Groningen

Completed

Feasibility of the Combination of Chemotherapy (Carbo/Caelyx or Carbo/Doxorubicin) With Tocilizumab (mAb IL-6R) and Peg-Intron in Patients With Recurrent Ovarian Cancer (PITCH)

Recurrent Ovarian Cancer

Netherlands
Hospital Clinico Universitario de Santiago
Fundación Ramón Domínguez

Completed

Tocilizumab Treatment in Graves´ Ophthalmopathy (Graves´ Orbitopathy or Thyroid Eye Disease) (GRC)

Thyroid Eye Disease | Thyroid Associated Ophthalmopathies | Graves´ Ophthalmopathy

Spain
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) Plus DMARDs in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

South Africa
Hoffmann-La Roche

Completed

An Observational Study of RoActemra/Actemra (Tocilizumab) in Monotherapy in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Sweden, Denmark, Norway
Hoffmann-La Roche

Completed

A Pharmacodynamic Study to Evaluate Neutrophil Distribution Kinetics and Function Following Single-Dose RoActemra/Actemra (Tocilizumab) in Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Turkey
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra and, if Initially Inadequately Responded to RoActemra/Actemra, Followed by MabThera/Rituxan in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Germany
Hoffmann-La Roche

Completed

A Study in Patients With Moderate to Severe Active Rheumatoid Arthritis Comparing Different Infusion Durations of RoActemra/Actemra (Tocilizumab) Treatment

Rheumatoid Arthritis

Denmark, Iceland
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) Given Subcutaneously in Combination With Traditional DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

Poland, United States, Colombia, Brazil, Canada, South Africa, Spain, Greece, Russian Federation, Switzerland, Thailand, Bulgaria, Israel, Mexico, Hungary, Argentina, Panama, Philippines, Guatemala, Malaysia, Australia, New Zealand
Hoffmann-La Roche

Completed

An Exploratory Study of Tocilizumab in Patients With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Current Non-Biologic DMARDs and/or Anti-TNF Therapy.

Rheumatoid Arthritis

Belgium, Czech Republic, France, Italy, Spain, Sweden, United Kingdom, Canada, Greece, Ireland, Portugal, Turkey, Netherlands, Denmark, Finland, Germany, Luxembourg, Austria, Switzerland, Poland, Australia, Hungary, Saudi Arabia, Romania and more
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) With or Without Methotrexate in Patients With Mild to Moderate Rheumatoid Arthritis With an Inadequate Response to Methotrexate

Rheumatoid Arthritis

Austria
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate Versus RoActemra/Actemra Monotherapy in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate

Rheumatoid Arthritis

Spain
Spanish Foundation of Rheumatology
Roche Farma, S.A

Unknown

Uncontrolled Study to Evaluate Efficacy of Tocilizumab in Patients With Moderate or Severe Rheumatoid Arthritis

Arthritis, Rheumatoid

Spain

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