Clinical Trials Sponsored by Aadi, LLC

Total 10857 results

Northwestern University
Nadi, LLC

Active, not recruiting

Open-source Hearing Aid Platform Comparisons (COSP-1)

Hearing Loss | Hearing Loss, Sensorineural

United States
Sarcoma Oncology Research Center, LLC
Aadi Bioscience, Inc.

Completed

Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers

Melanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Ewing Sarcoma | Non Small Cell Lung Cancer | Chordoma | Urothelial Carcinoma | Classical Hodgkin Lymphoma | PEComa | Desmoid Tumor | Epithelioid Sarcoma | Squamous Cell Carcinoma | MTOR Activating Mutation

United States
Aadi Bioscience, Inc.

Recruiting

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

Cancer | Endometrial Cancer | Tumor | Recurrent Endometrial Carcinoma | Endometrioid Endometrial Cancer | Endometrioid Tumor

United States
Aadi Bioscience, Inc.

Completed

Nab-sirolimus in Recurrent High Grade Glioma and Newly Diagnosed Glioblastoma

High Grade Recurrent Glioma and Newly Diagnosed Glioblastoma

United States
Aadi Bioscience, Inc.

Completed

A Phase 2 Study of Nab-sirolimus (ABI-009) in Patients With Advanced Malignant PEComa (AMPECT)

Malignant PEComa

United States
Aadi Bioscience, Inc.

Active, not recruiting

ABI-009, an mTOR Inhibitor, for Patients With Severe Pulmonary Arterial Hypertension

Pulmonary Hypertension

United States
Aadi Bioscience, Inc.

Withdrawn

ABI-009 (Nab-sirolimus) in Patients With Genetically-confirmed Leigh or Leigh-like Syndrome

Leigh Syndrome
Aadi Bioscience, Inc.

Recruiting

Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors (NETs) of the Gastrointestinal Tract, Lung, or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors

Neuroendocrine Tumors | Pancreatic Neuroendocrine Tumor | Gastrointestinal Neuroendocrine Tumor | NET | Pulmonary Neuroendocrine Tumor

United States
Aadi Bioscience, Inc.

Approved for marketing

Expanded Access for ABI-009 in Patients With Advanced PEComa and Patients With a Malignancy With Relevant Genetic Mutations or mTOR Pathway Activation

TSC1 | TSC2 | PEComa, Malignant | mTOR Pathway Abberation
Aadi Bioscience, Inc.

Recruiting

Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment

Advanced Solid Tumor | Tumor | Tumor, Solid

United States
Aadi Bioscience, Inc.

Recruiting

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

Malignant Solid Neoplasm | Neoplasms | Cancer | Neoplasm Metastasis | Solid Tumor | Metastatic Cancer | Metastasis | Advanced Solid Tumor | Metastatic Solid Tumor | Advanced Cancer | Tumor | Malignant Neoplasm | Malignant Tumor | Tumors | Cancer Metastatic | Tumor, Solid | Malignant Solid Tumor | TSC | TSC1 | TSC2 | Metastatic Neoplasm

Korea, Republic of, United States, Puerto Rico
Aadi Bioscience, Inc.

Completed

Nab-Sirolimus in Combination With FOLFOX & BEV as 1st Line Therapy in Patients With Advanced or Metastatic Colorectal Cancer

Colorectal Cancer Metastatic

United States
Massachusetts General Hospital
Aadi Bioscience, Inc.

Withdrawn

Safety and Efficacy of ABI-009 (Nab-rapamycin) in Combination With Pomalidomide and Dexamethasone for Relapsed and Refractory Multiple Myeloma

Multiple Myeloma

United States
M.D. Anderson Cancer Center
Aadi Bioscience

Not yet recruiting

A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions

Leiomyosarcoma | Soft-tissue Sarcomas

United States
Mirati Therapeutics Inc.
Aadi Bioscience, Inc.

Recruiting

Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19)

NSCLC | Metastatic Cancer | Advanced Cancer | Solid Tumor, Adult | Malignant Neoplastic Disease

United States
Seattle Children's Hospital
Aadi Bioscience, Inc.

Completed

ABI-009 (Nab-rapamycin) for Surgically-Refractory Epilepsy (RaSuRE)

Epilepsy Intractable

United States
University of Washington
Aadi Bioscience, Inc.

Active, not recruiting

Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas

Advanced Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Locally Advanced Soft Tissue Sarcoma

United States
Maadi Military Hospital

Unknown

Study to Justify Steroid Use in Preterm Neonates to Prevent Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia

Egypt
Aadi Bioscience, Inc.
National Cancer Institute (NCI)

Completed

Phase 1/2 Study of ABI-009 in Nonmuscle Invasive Bladder Cancer

Non-muscle Invasive Bladder Cancer (NMIBC)

United States
Al Hadi Hospital

Completed

IVI Aflibercept Before and After Phaco in DME.

Diabetic Macular Edema

Kuwait
Al Hadi Hospital

Completed

Intravitreal Aflibercept Injection or Early Vitrectomy for Diabetic Vitreous Hemorrhage

Diabetic Vitreous Hemorrhage

Kuwait
Al Hadi Hospital

Completed

Aflibercept With and Without Micropulse Laser in Diabetic Macular Edema (MPL)

Diabetic Macular Edema

Kuwait
Abdi İbrahim Otsuka

Completed

Effects of Aripiprazole (LAI) on Phychosocial/Cognitive Functioning, pt Reported AcceptabilityofTreatment in Sch (ARILAI)

Schizophrenia

Turkey
Robert Ramirez
Aadi Bioscience, Inc.

Terminated

A Study to testABI-009 in Patients With Metastatic, Unresectable, Low or Intermediate Grade Neuroendocrine Tumors of the Lung or Gastroenteropancreatic System

Neuroendocrine Tumors

United States
Adai Technology (Beijing) Co., Ltd.

Completed

Gamified Adaptive Approach Bias Modification on Individuals With Methamphetamine Use History

Addiction, Substance

China
Fadi Haddad, M.D.

Unknown

IgG/IgM Antibody Test in Patients Who Have Tested Negative or Positive for COVID-19 With the Standard Method of COVID19 Testing.

SARS-CoV 2

United States
Arthritis Northwest PLLC
Epigenesys LLC

Unknown

Identification of Epigenetic Biomarkers for Early Detection of Rheumatic Disease

Arthritis, Rheumatoid

United States
Angle plc
MidLantic Urology, LLC

Terminated

Characterization of Circulating Tumor Cells (CTCs) in High Risk and Early Metastatic Prostate Cancer Patients Using Parsortix® System (CHARTER)

Prostate Cancer | Castration-resistant Prostate Cancer | Biochemically Recurrent Prostate Carcinoma | High Risk Prostate Carcinoma

United States
Adai Technology (Beijing) Co., Ltd.

Not yet recruiting

Depression in Patients With Mild to Moderate Depression

Depression
Adai Technology (Beijing) Co., Ltd.

Recruiting

Digital Intervention for Depression and Anxiety in Adolescents

Depression | Anxiety

China
Adai Technology (Beijing) Co., Ltd.

Completed

Game-Based Digital Intervention for Relieving Depression and Anxiety Symptoms

Depression | Anxiety

China
University of Baghdad
Afnan Hadi Khudhayer

Completed

Heart-health Promotion

Heart Diseases

Iraq
Synochi, LLC
LAC+USC Medical Center

Not yet recruiting

Prospective Placebo-controlled Study of Synochi Scar Spray

Burns Multiple
LLS PedAL Initiative, LLC
Kura Oncology

Not yet recruiting

Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

Relapsed/Refractory KMT2A-r Acute Leukemia | Relapsed/Refractory NUP98-r Acute Leukemia | Relapsed/Refractory NPM1-m Acute Leukemia
Derm Research, PLLC
WFH MEDICAL, LLC

Completed

Aczone 5% Gel as Maintenance Treatment of Acne Vulgaris Following Completion of Oral Doxycycline and Aczone 5% Gel

Acne Vulgaris

United States
Verily Life Sciences LLC
The Emmes Company, LLC; Optos, PLC; Google LLC.; Nikon Corporation

Completed

ARDA Software for the Detection of mtmDR

Diabetic Retinopathy

United States
Par Pharmaceutical, Inc.
AAI Clinic

Completed

Bioavailability Study of Tramadol/APAP Tablets Under Fed Conditions

To Determine Bioequivalence Under Fed Conditions
Abdi Ibrahim Ilac San. ve Tic A.S.

Completed

Efficacy and Safety Study of Udenafil Tablets in Erectile Dysfunction.

Erectile Dysfunction

Turkey
MedRegen LLC
Johns Hopkins University; ICON plc

Recruiting

MRG-001 as an Immunoregulatory and Regenerative Therapy for COVID-19 Patients

COVID-19 | ARDS, Human | Regeneration | Stem Cells

United States
Par Pharmaceutical, Inc.
AAI Clinic

Completed

Bioavailability Study of Tramadol/APAP Tablets Under Fasting Conditions

To Determine Bioequivalence Under Fasting Conditions
Redx Pharma Plc
Merck Sharp & Dohme LLC

Completed

A Study to Assess RXC004 Efficacy in Advanced Solid Tumours After Progression on Standard of Care (SoC) Therapy (PORCUPINE2) (KEYNOTE-E86)

Advanced Solid Tumours

United Kingdom, Australia
4D pharma plc
Merck Sharp & Dohme LLC

Terminated

Live Biotherapeutic Product MRx0518 and Pembrolizumab Combination Study in Solid Tumors

Melanoma | Renal Cell Carcinoma | Solid Tumor | Non Small Cell Lung Cancer | Bladder Cancer | Oncology

United States
Anas Radi Hassan Alashram

Completed

Dry Needling Effects Post-traumatic Brain Injury

Traumatic Brain Injury

Jordan
Egyptian Liver Hospital
Wadi El Nil Hospital

Completed

Randomized, Open-Label, Study to Evaluate the Safety and Efficacy of Sofosbuvir Tablet Plus Ribavirin Tablet (Part A) Versus Single Dose (2 Tablets) of EHCV Containing Sofosbuvir, Ribavirin, and Natural Anti-hemolytic (B) in Egyptian Adults With Chronic Genotype 4 HCV Infection

Hepatitis c

Egypt
Abdi Ibrahim Ilac San. ve Tic A.S.

Completed

Metabolic Syndrome Prevalence Study

Metabolic Syndrome

Turkey
IVFarma LLC
BridgePharm LLC; GlobalPharma LLC

Completed

Study to Compare Efficacy and Safety of Primapur and Gonal-f in Women for Assisted Reproductive Treatment

Infertility, Female

Russian Federation
ClinAmygate
As-Salam Center, Maadi, Cairo, Egypt

Recruiting

Post-COVID-19 Chronic Fatigue Syndrome

Post-COVID-19 Syndrome | Post-COVID Syndrome

Egypt
Anas Radi Hassan Alashram

Not yet recruiting

Closed Kinetic Chain Exercises for Balance and Gait Rehabilitation for People With MS

Multiple Sclerosis

Jordan
Iman Abd-ElWahab Radi, PhD

Not yet recruiting

Socket Shield Technique Versus Early Implant Placement With Contour Augmentation

Bone Loss | Bone Resorption

Egypt
Iman Abd-ElWahab Radi, PhD

Completed

Patient Satisfaction and OHRQoL In Removable Versus Fixed Implant Prostheses

Completely Edentulous Patients

Egypt

Clinical Trials Sponsored by Aadi, LLC

Sponsors and Collaborators

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