Clinical Trials Sponsored by Imperial College Healthcare National Health Service Trust

Total 60 results

Imperial College London
Imperial College Healthcare NHS Trust; Imperial Health Charity

Completed

Avoidance of Hyperglycaemia in People With Type 1 Diabetes (HYPE)

Diabetes Mellitus, Type 1

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom; Imperial College Healthcare...

Withdrawn

MRI Assessment of Myocardial Fibrosis Associated With Monocyte Phenotype in End Stage Renal Failure (CM3)

Myocardial Fibrosis | Heart Failure | End Stage Renal Failure on Dialysis | Chronic Kidney Disease Stage V | Chronic Kidney Disease, Stage IV (Severe)

United Kingdom
Imperial College London
National Health Service, United Kingdom

Completed

Incentives in Diabetic Eye Assessment by Screening (IDEAS)

Diabetes | Diabetic Retinopathy
Imperial College London
National Health Service, United Kingdom

Terminated

Rifaximin in Fatty Liver Disease (RiFL)

NAFLD | Nonalcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis

United Kingdom
Imperial College Healthcare NHS Trust
National Institute for Health Research, United Kingdom

Completed

Low Dose Peri-operative IV Ketamine for Chronic Post-surgery Pain Prevention

Chronic Postoperative Pain

United Kingdom
Imperial College Healthcare NHS Trust
National Institute for Health Research, United Kingdom

Completed

Effects of Oral Sodium Bicarbonate Supplementation in Haemodialysis Patients (BicHD) (BicHD)

End-stage Renal Disease

United Kingdom
Imperial College Healthcare NHS Trust
National Institute for Health Research, United Kingdom

Terminated

The Role of Ambulatory Oxygen in Improving the Effectiveness of Pulmonary Rehabilitation for COPD Patients

Chronic Obstructive Pulmonary Diseases

United Kingdom
Intensive Care National Audit & Research Centre
Imperial College Healthcare NHS Trust

Completed

Evaluation of the Association Between Day and Time of Admission to Critical Care and Acute Hospital Outcome

Critical Illness
Golden Jubilee National Hospital
NHS Lothian; Imperial College Healthcare NHS Trust

Unknown

Effects of Apelin on the Lung Circulation in Pulmonary Hypertension

Heart Failure | Pulmonary Arterial Hypertension

United Kingdom
Imperial College London
Royal Marsden NHS Foundation Trust; Chelsea and Westminster NHS Foundation... and other collaborators

Recruiting

COlorectal BReath Analysis (COBRA2)

Colorectal Cancer

United Kingdom
Imperial College London
National Institute for Health Research, United Kingdom; Imperial Health Charity and other collaborators

Active, not recruiting

The Colorectal Breath Analysis (COBRA) Study (COBRA)

Colorectal Cancer | Colorectal Polyps | Colorectal Adenocarcinoma

United Kingdom
Imperial College Healthcare NHS Trust
The Behavioural Insights Team; Central London CCG; Imperial College Health Partners and other collaborators

Not yet recruiting

Using Text Messages to Improve COVID-19 Vaccination Uptake

Covid19
Imperial College London
Wellcome Trust; National Institute for Health Research, United Kingdom

Completed

The Safety and Immunogenicity of a Potential HIV Vaccine

HIV Infections

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...
Newcastle-upon-Tyne Hospitals NHS Trust; Imperial College Healthcare NHS Trust

Not yet recruiting

The RIPPLE AT-PLUS Study

Atrial Tachycardia

United Kingdom
Imperial College London
University of Southern California; Guy's and St Thomas' NHS Foundation Trust; Ipse... and other collaborators

Terminated

A Study to Assess the Ability of a Novel Endocrine Treatment for Breast Cancer, Irosustat, to Slow Down Cancer Growth (IPET)

Breast Neoplasms

United Kingdom
Imperial College London
UMC Utrecht; Dr. Reddy's Laboratories Limited; Royal College of Surgeons, Ireland and other collaborators

Completed

UMPIRE - Use of a Multidrug Pill In Reducing Cardiovascular Events (UMPIRE)

Cardiovascular Diseases

Australia, India, Ireland, Netherlands, United Kingdom
Imperial College London
Medical Research Council; Wellcome Trust; National Institute for Health Research...

Terminated

A Study of Protective Immunity Against RSV and Influenza in Experimental Human Challenge of Volunteers

Influenza, Human | Respiratory Syncytial Virus Infections

United Kingdom
my mhealth Ltd
Imperial College London; Hull University Teaching Hospitals NHS Trust; Innovate... and other collaborators

Completed

Clinical Efficacy and Cost Effectiveness of MYCOPD in Patients With Mild and Moderate Newly Diagnosed COPD (EARLY)

COPD

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; National Institute for Health...

Completed

Intelligent Oxygen Therapy During Activities of Daily Living

Hypoxia | COPD | Hyperoxia

United Kingdom
Imperial College London
Guy's and St Thomas' NHS Foundation Trust; University Hospital Southampton... and other collaborators

Recruiting

Intervention With Cerebral Embolic Protection in TEVAR: Gaseous Protection (INTERCEPT:GP)

Stroke | Neurocognitive Dysfunction | Silent Cerebral Infarction | Vascular Brain Injury

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; Imperial College London; National Institute for Health...

Completed

The Grown Up Peanut Immunotherapy Study (GUPI)

Peanut Allergy

United Kingdom
University of Cambridge
Imperial College London; Cambridge University Hospitals NHS Foundation Trust; Wellcome Trust and other collaborators

Active, not recruiting

PET Imaging of Giant Cell and Takayasu Arteritis (PITA)

Giant Cell Arteritis | Takayasu Arteritis

United Kingdom
Imperial College London
University Hospitals, Leicester; Medical University of Silesia; Royal Brompton... and other collaborators

Completed

Randomised Ischaemic Mitral Evaluation (RIME) Trial (RIME)

Coronary Artery Disease | Mitral Regurgitation

United Kingdom, Poland
King's College Hospital NHS Trust
King's College London; University College London Hospitals; University of Sheffield and other collaborators

Recruiting

RElated Haplo-DonoR Haematopoietic stEm Cell Transplantation for Adults With Severe Sickle Cell Disease (REDRESS)

Sickle Cell Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
London School of Hygiene and Tropical Medicine; King's College London; King's... and other collaborators

Completed

A Randomised Trial of Expedited Transfer to a Cardiac Arrest Centre for Non-ST Elevation Out-of-hospital Cardiac Arrest (ARREST)

Out-Of-Hospital Cardiac Arrest

United Kingdom
Imperial College London
Chelsea and Westminster NHS Foundation Trust; National Heart and Lung Institute and other collaborators

Completed

Defining the Intestinal Microbiota in Premature Neonates

Necrotizing Enterocolitis | Premature Intestinal Microbiota | Late Onset Bloodstream Infection

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Imperial College London; British Lung Foundation; National Heart and Lung Institute

Completed

The Use of Inflammatory Markers to Guide Therapy in Children With Severe Asthma

Asthma

United Kingdom
Imperial College London
Cambridge University Hospitals NHS Foundation Trust; National Institute for... and other collaborators

Active, not recruiting

Transplant Antibody-Mediated Rejection: Guiding Effective Treatments (TAR:GET-1)

Kidney Transplant Rejection | Antibody-mediated Rejection

United Kingdom
University Hospital Southampton NHS Foundation...
Royal Marsden NHS Foundation Trust; University College London Hospitals; Cambridge... and other collaborators

Unknown

Coronavirus Infection in Primary or Secondary Immunosuppressed Children and Adults. (ImmunoCOVID)

COVID | Infection | Immune Deficiency | Immune Suppression | Children, Adult

United Kingdom
Imperial College London
University Hospital Southampton NHS Foundation Trust; National Institute for... and other collaborators

Unknown

EndoBarrier TM Gastrointestinal Liner Diabetes Trial (EndoBarrier)

Diabetes | Overweight and Obesity

United Kingdom
Imperial College London
Royal Marsden NHS Foundation Trust; University College London Hospitals; The... and other collaborators

Completed

Cancer Loyalty Card Study (CLOCS)

Ovarian Neoplasms

United Kingdom
Imperial College Healthcare NHS Trust
Barts & The London NHS Trust; Royal Free Hospital NHS Foundation Trust; University... and other collaborators

Active, not recruiting

TB PCR in BAL and EBUS-TBNA (TRiBE)

Tuberculosis

United Kingdom
Imperial College London
National Heart Foundation, Australia; Royal Brompton & Harefield NHS Foundation... and other collaborators

Completed

Radial Artery Versus Saphenous Vein Patency (RSVP) Study (RSVP)

Coronary Arteriosclerosis

United Kingdom
University of Hertfordshire
University of Southampton; University of Plymouth; Imperial College Healthcare... and other collaborators

Recruiting

A Study to Evaluate the Introduction of New Staffing Models in Intensive Care: a Realist Evaluation (SEISMIC-R) (SEISMIC-R)

Critical Illness | Intensive Care | Staff Attitude | Organisation

United Kingdom
University of Southampton
University of Maryland; Imperial College London; National Institute for Health... and other collaborators

Unknown

Mechanical Muscle Activity With Real-time Kinematics (M-MARK): A Novel Combination of Existing Technologies to Improve Arm Recovery Following Stroke

Stroke
Guy's and St Thomas' NHS Foundation Trust
University of Nottingham; Imperial College London; University College, London; Cambridge... and other collaborators

Not yet recruiting

BEARS Training Package to Maximise Hearing Abilities in Older Children and Teenagers With Bilateral Cochlear Implants (BEARS)

Hearing Loss | Deafness | Hearing Loss, Sensorineural | Hearing Impaired Children and Adolescents
University of Ulster
Belfast Health and Social Care Trust; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

Awareness Detection and Communication in Disorders of Consciousness

Stroke | Paralysis | Motor Neuron Disease | Disorder of Consciousness | Physical Disability

United Kingdom, Ireland
Royal Marsden NHS Foundation Trust
Imperial College London; Royal Brompton & Harefield NHS Foundation Trust; Institute... and other collaborators

Recruiting

AI & Radiomics for Stratification of Lung Nodules After Radically Treated Cancer (AI-SONAR)

Lung Cancer | Lung Metastases | Indeterminate Pulmonary Nodules | Second Primary Cancer

United Kingdom
Imperial College London
University College London Hospitals; Northern Care Alliance NHS Foundation... and other collaborators

Recruiting

Augmented Response of Volatile Biomarkers in Assessment of Oesophagogastric Cancer (AROMA 1 / BIORESOURCE)

Gastric Cancer | Oesophageal Cancer | Microbiome | Volatile Organic Compounds | Transcriptomics | Microbioata | Breath Analysis | Volatalomics | Metabonomics/Lipidomics | Microbiome Analysis

United Kingdom
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Norfolk and Norwich University Hospitals... and other collaborators

Completed

Idiopathic Pulmonary Fibrosis Job Exposures Study (IPFJES)

Idiopathic Pulmonary Fibrosis | IPF

United Kingdom
Portsmouth Hospitals NHS Trust
King's College Hospital NHS Trust; University College London Hospitals; Northern... and other collaborators

Completed

A Evaluation of the Utilisation, Effectiveness and Safety of Purastat® in the Management of Gastrointestinal Bleeding (POPS)

Gastrointestinal Bleeding

United Kingdom
University College, London
London School of Hygiene and Tropical Medicine; King's College London; University... and other collaborators

Recruiting

Deep Brain Stimulation in Tourette Syndrome (Op-TICS)

Tourette Syndrome | Deep Brain Stimulation

United Kingdom
University of Birmingham
Royal Marsden NHS Foundation Trust; The Leeds Teaching Hospitals NHS Trust; Guy... and other collaborators

Active, not recruiting

Measuring the Quality of Surgical Care and Setting Benchmarks for Training Using Intuitive Data Recorder Technology (MASTERY)

Cancer | Surgery

United Kingdom
University College, London
King's College London; Imperial College London; National Institute for Health... and other collaborators

Unknown

Dementia Early Recognition and Response in Primary Care (EVIDEM-ED)

Dementia

United Kingdom
University of Bristol
University College, London; National Institute for Health Research, United... and other collaborators

Completed

Cortisol Evaluation in Abuse Survivors (CEASE)

Depression | Posttraumatic Stress Disorders | Anxiety | Panic Disorder | Domestic Violence

United Kingdom
Seoul National University Hospital
Samsung Medical Center; Ulsan University Hospital; Inje University; Keimyung University... and other collaborators

Completed

International Collaboration of Comprehensive Physiologic Assessment

Stable Angina | ST-segment Elevation Myocardial Infarction | Unstable Angina | Non-ST Elevation Myocardial Infarction

Korea, Republic of, Japan, Spain
University of Oxford
King's College Hospital NHS Trust; Nottingham University Hospitals NHS Trust; Guy's and St Thomas' NHS Foundation Trust and other collaborators

Enrolling by invitation

Echocardiography: Value and Accuracy at REst and STress (EVAREST)

Coronary Artery Disease | Angina Pectoris | Ischaemic Heart Disease
University of Leeds
University College London Hospitals; The Leeds Teaching Hospitals NHS Trust; Sheffield... and other collaborators

Completed

TReatment of Irritable Bowel Syndrome With Diarrhoea Using Titrated ONdansetron Trial (TRITON)

IBS - Irritable Bowel Syndrome

United Kingdom
Tan Tock Seng Hospital
Melbourne Health; National University Hospital, Singapore; Samsung Medical Center and other collaborators

Recruiting

Early Oral Step-down Antibiotic Therapy for Uncomplicated Gram-negative Bacteraemia

Gram-negative Bacteraemia

Singapore
University College, London
London School of Hygiene and Tropical Medicine; King's College London; Odense... and other collaborators

Completed

Effect of Remote Ischaemic Conditioning on Clinical Outcomes in STEMI Patients Undergoing PPCI (CONDI2/ERIC-PPCI)

Myocardial Reperfusion Injury | STEMI

Denmark, United Kingdom, Spain, Serbia

Clinical Trials Sponsored by Imperial College Healthcare National Health Service Trust

Sponsors and Collaborators

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CROs in Morocco

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