Clinical Trials Sponsored by Imperial College Healthcare Trust, St Mary's Hospital

Total 93 results

Imperial College London
St Mary's Hospital, London

Suspended

Total Cerebral Protection With Embolic Protection Devices Thoracic Aortic Stenting

Stroke | Silent Cerebral Infarct

United Kingdom
Imperial College London
Guy's and St Thomas' NHS Foundation Trust; Imperial College Healthcare NHS...

Recruiting

Assessment, Monitoring and Optimisation of Prehabilitation Patients Using Wearable Fitness Trackers

Cancer

United Kingdom
Imperial College London
St Mark's Hospital Foundation; CORE

Completed

Plasma Determination of Glucagon-like Peptide 2 as a Predictor of Recovery in Adults With Acute Intestinal Failure

Short Bowel Syndrome
Imperial College Healthcare NHS Trust
Imperial College London; The Wellington Hospital, London

Completed

Measurements of Angulation of the C-spine

Cervical Spine

United Kingdom
Imperial College London
Cambridge University Hospitals NHS Foundation Trust; Imperial College Healthcare...

Completed

Predictive of Biomarkers of Healing in Chronic Venous Ulceration of the Lower Limb (MOJITO)

Varicose Ulcer

United Kingdom
King's College London
King's College Hospital NHS Trust; Imperial College London; Guy's and St Thomas... and other collaborators

Not yet recruiting

Trial of Mirtazapine for Depression in IBD (MDIBD)

Inflammatory Bowel Diseases | Major Depressive Disorder
Imperial College London
Imperial College Healthcare NHS Trust; London North West Healthcare NHS Trust; Chelsea and Westminster Hospital NHS Foundation Trust

Recruiting

Artificial Intelligence-assisted Diagnosis and Prognostication in COVID-19 Using Electrocardiograms (AI-COV-19)

Coronavirus

United Kingdom
Imperial College Healthcare NHS Trust
Imperial College London; University of Oxford; Oxford University Hospitals NHS...

Withdrawn

SABRE: A Single-arm Prospective Study Measuring Safety and Tolerability of SARS-CoV-2 Neutralising Antibodies in High-risk Populations (SABRE)

Lymphoma | Leukemia | Immune Thrombocytopenia | SARS-CoV2 Infection | SARS-CoV-2 Acute Respiratory Disease | Myeloma | Thrombotic Thrombocytopenic Purpura (TTP)

United Kingdom
Imperial College London
Medical Research Council; Imperial College Healthcare NHS Trust; University Hospital...

Completed

Ciclosporin in HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP) (HAM05)

HTLV I Associated Myelopathy

United Kingdom
London North West Healthcare NHS Trust
St Mark's Hospital Foundation

Unknown

Nutritional Management of Acute and Chronic Enterocutaneous Fistulae

Enterocutaneous Fistulae

United Kingdom
Imperial College London
Royal Free Hospital NHS Foundation Trust; Mid and South Essex NHS Foundation... and other collaborators

Not yet recruiting

Multivessel Balloon Occlusion to Investigate Obstructive Coronary Artery Disease and aNgina (ORBITA-MOON)

Stable Angina | Multivessel Coronary Artery Disease

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Imperial College Healthcare NHS Trust; Royal Cornwall Hospitals Trust

Unknown

Assessment of Olfactory Dysfunction in SARS CoV-2 (COVID-19) Infection (ODYSSI)

Quality of Life | Anosmia | SARS-CoV-2 | COVID19 | Olfactory Disorder | Microsomia | Smell Disorder

United Kingdom
Imperial College London
Barking, Havering and Redbridge University Hospitals NHS Trust; Imperial College... and other collaborators

Recruiting

Profiling Microbiome Associated Metabolic Pathways in Oesophageal Cancer Survivors (MAPLES)

Quality of Life | Oesophageal Cancer | Bacterial Overgrowth

United Kingdom
Womb Transplant UK
Oxford University Hospitals NHS Trust; Imperial College Healthcare NHS Trust

Recruiting

INvestigational Study Into Transplantation of the Uterus (INSITU)

Cervical Cancer | Postpartum Hemorrhage | Mayer-Rokitansky-Kuster Syndrome | Asherson's Syndrome

United Kingdom
University Hospital Southampton NHS Foundation...
Imperial College London; University of Bristol; University Hospitals Bristol... and other collaborators

Completed

Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study (StePS)

Sepsis

United Kingdom
Accunea Ltd.
Imperial College Healthcare NHS Trust; Hammersmith Hospitals NHS Trust; Innovate...

Withdrawn

Detecting Markers of Kidney Function With Intravenous Microdialysis

Kidney Diseases

United Kingdom
Golden Jubilee National Hospital
NHS Lothian; Imperial College Healthcare NHS Trust

Unknown

Effects of Apelin on the Lung Circulation in Pulmonary Hypertension

Heart Failure | Pulmonary Arterial Hypertension

United Kingdom
Ourotech, Inc.
Barts & The London NHS Trust; Imperial College Healthcare NHS Trust; Hampshire... and other collaborators

Recruiting

Prospective Evaluation of AI R&D Tool for Patient Stratification - MoA Evaluation in Triple Negative Breast Cancer (PEAR-MET) (PEAR-MET)

Breast Cancer | Triple Negative Breast Cancer

United Kingdom
King's College London
King's College Hospital NHS Trust; Guy's and St Thomas' NHS Foundation Trust; Imperial College Healthcare NHS Trust and other collaborators

Completed

Mental Wellbeing and Quality of Life in Prostate Cancer (MIND-P)

Prostate Cancer

United Kingdom
Imperial College London
University College London Hospitals; Guy's and St Thomas' NHS Foundation Trust

Completed

Neuroprotective Effects of Hypothermia Combined With Inhaled Xenon Following Perinatal Asphyxia (TOBYXe)

Hypoxic Ischaemic Encephalopathy

United Kingdom
Royal Free Hospital NHS Foundation Trust
University Hospital Tuebingen; Imperial College Healthcare NHS Trust; Ankara...

Unknown

Accuracy of the LiverVision® Semi-automated Liver Volumetry Software (LiverVision)

Liver Diseases | Liver Cancer

Germany, United Kingdom, Turkey
Imperial College London
GlaxoSmithKline; University College, London; Medical Research Council; Queen Mary... and other collaborators

Completed

Patient Research Cohort: Rapidly Evolving Multiple Sclerosis (PRC-REMS)

Relapsing-remitting Multiple Sclerosis | Secondary Progressive Multiple Sclerosis

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...
Newcastle-upon-Tyne Hospitals NHS Trust; Imperial College Healthcare NHS Trust

Not yet recruiting

The RIPPLE AT-PLUS Study

Atrial Tachycardia

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
Imperial College London; Barts & The London NHS Trust; University of Cambridge; Imperial College Healthcare NHS Trust

Completed

Biomarkers of Acute Serious Illness in Children (BASIC)

Critical Illness | Children, Only | Infection, Mixed

United Kingdom
Imperial College London
Guy's and St Thomas' NHS Foundation Trust; Liverpool University Hospitals NHS... and other collaborators

Recruiting

Coronary Sinus Reducer Implantation in Patients With Ischaemia and Non-obstructed Coronary Arteries and Coronary Microvascular Dysfunction. (REMEDY-PILOT)

Coronary Disease | Angina Pectoris | Refractory Angina | Microvascular Angina | Microvascular Coronary Artery Disease

United Kingdom
Imperial College Healthcare NHS Trust
University College London Hospitals; University College, London; University of... and other collaborators

Not yet recruiting

Imperial Prostate 9 - ATLAS (Approaches To Long-Term Active Surveillance) (IP9-ATLAS)

Prostate Cancer
Imperial College Healthcare NHS Trust
Cambridge University Hospitals NHS Foundation Trust; Mid and South Essex NHS...

Completed

Adherence and Acceptability of a Remote, Home-based, Pre-surgery Programme for Patients Undergoing Abdominal Aortic Aneurysm Surgery

Aortic Aneurysm, Abdominal

United Kingdom
Imperial College London
King's College Hospital NHS Trust; University College London Hospitals; Cambridge... and other collaborators

Active, not recruiting

National Institute for Health Research (NIHR) Health Informatics Collaborative Troponin Study (NHIC-Troponin)

Mortality | Acute Coronary Syndrome | Troponin | Age
Ourotech, Inc.
Royal Free Hospital NHS Foundation Trust; Imperial College Healthcare NHS Trust and other collaborators

Not yet recruiting

Prospective Evaluation of AI R&D Tool for Patient Stratification: a Trial for Renal Immuno-oncology Model Experimental Evaluation 2 (PEAR-TREE2)

Kidney Cancer | Renal Cell Cancer Metastatic

United Kingdom
Imperial College London
Guy's and St Thomas' NHS Foundation Trust; University Hospital Southampton... and other collaborators

Recruiting

Intervention With Cerebral Embolic Protection in TEVAR: Gaseous Protection (INTERCEPT:GP)

Stroke | Neurocognitive Dysfunction | Silent Cerebral Infarction | Vascular Brain Injury

United Kingdom
Imperial College London
University of Southern California; Guy's and St Thomas' NHS Foundation Trust; Ipse... and other collaborators

Terminated

A Study to Assess the Ability of a Novel Endocrine Treatment for Breast Cancer, Irosustat, to Slow Down Cancer Growth (IPET)

Breast Neoplasms

United Kingdom
University of Oxford
Imperial College Healthcare NHS Trust; Fortius Clinic; BUPA Cromwell Hospital...

Unknown

Predicting Osteoarthritis Risk Following Knee Injury. (KICK)

Osteoarthritis | Injury

United Kingdom
King's College Hospital NHS Trust
King's College London; University College London Hospitals; University of Sheffield and other collaborators

Recruiting

RElated Haplo-DonoR Haematopoietic stEm Cell Transplantation for Adults With Severe Sickle Cell Disease (REDRESS)

Sickle Cell Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
London School of Hygiene and Tropical Medicine; King's College London; King's... and other collaborators

Unknown

TAPS2 Transfusion Antenatally in Pregnant Women With SCD (TAPS2)

Pregnancy, High Risk | Sickle Cell Disease | Blood Transfusion Complication

United Kingdom
King's College London
Imperial College London; Medical Research Council; Guy's and St Thomas' NHS Foundation... and other collaborators

Unknown

Treg Immunotherapy in Crohn's Disease (TRIBUTE)

Crohn Disease
Imperial College Healthcare NHS Trust
Nottingham University Hospitals NHS Trust; Barts & The London NHS Trust; Hospital... and other collaborators

Completed

Ripple Mapping Guided Ablation of Ischaemic Ventricular Tachycardia. (RIPPLE-VT)

Ischemic Heart Disease | Ventricular Tachycardia

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
London School of Hygiene and Tropical Medicine; King's College London; King's... and other collaborators

Completed

A Randomised Trial of Expedited Transfer to a Cardiac Arrest Centre for Non-ST Elevation Out-of-hospital Cardiac Arrest (ARREST)

Out-Of-Hospital Cardiac Arrest

United Kingdom
Imperial College London
University College London Hospitals; Northern Care Alliance NHS Foundation... and other collaborators

Recruiting

Non-invasive Testing for Early oEesophageal Cancer and Dysplasia (NEED)

Barrett Esophagus | Oesophageal Cancer | Barretts Esophagus With Dysplasia

United Kingdom
University of Aberdeen
Imperial College London; Medical Research Council; Brighton and Sussex University... and other collaborators

Completed

Nitrites in Acute Myocardial Infarction (NIAMI)

Acute ST Elevation Myocardial Infarction

United Kingdom
University of Leeds
King's College London; Imperial College London; University of Oxford; University... and other collaborators

Recruiting

LOng COvid Multidisciplinary Consortium: Optimising Treatments and servIces Across the NHS (LOCOMOTION) (LOCOMOTION)

COVID-19

United Kingdom
University College, London
King's College Hospital NHS Trust; University College London Hospitals; Guy's... and other collaborators

Recruiting

Legacies and Futures: Measuring Roles of Resilience and Vulnerability in Pregnancy and Birth Outcomes

Pregnancy Related

United Kingdom
my mhealth Ltd
Imperial College London; Hull University Teaching Hospitals NHS Trust; Innovate... and other collaborators

Completed

Clinical Efficacy and Cost Effectiveness of MYCOPD in Patients With Mild and Moderate Newly Diagnosed COPD (EARLY)

COPD

United Kingdom
University of Manchester
King's College Hospital NHS Trust; Cardiff University; University College London... and other collaborators

Not yet recruiting

Immune Profiles in Myasthenia Gravis

Myasthenia Gravis
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma (VAPOR)

Pancreatic Cancer | PDAC - Pancreatic Ductal Adenocarcinoma

United Kingdom
St George's, University of London
University of Oxford; Ohio State University; University of Bristol; University... and other collaborators

Recruiting

Duroplasty for Injured Cervical Spinal Cord With Uncontrolled Swelling (DISCUS)

Spinal Cord Injuries

United Kingdom
Royal Marsden NHS Foundation Trust
King's College Hospital NHS Trust; University College London Hospitals; Guy's... and other collaborators

Recruiting

Lung Nodule Imaging Biobank for Radiomics and AI Research (LIBRA)

Lung Neoplasms | Lung Cancer | Pulmonary Nodule, Solitary | Pulmonary Nodule, Multiple

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Imperial College London and other collaborators

Active, not recruiting

Validation of an Artificial Intelligence Enabled Diagnostic Support Software (ArtiQ.Spiro) in Primary Care Spirometry Datasets - a Retrospective Analysis

Respiratory Disease

United Kingdom
University of Surrey
The Leeds Teaching Hospitals NHS Trust; University Hospital Birmingham NHS... and other collaborators

Recruiting

The National Transition Evaluation Study (NTES)

Young People With All Long-term Health Conditions

United Kingdom
Imperial College London
Royal Free Hospital NHS Foundation Trust; Mid and South Essex NHS Foundation... and other collaborators

Recruiting

Finding the Invasive Haemodynamic Threshold for Symptom Relief in Stable Angina (ORBITA-FIRE)

Stable Angina

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cambridge University Hospitals NHS Foundation... and other collaborators

Completed

Diffusion-weighted Imaging Study in Cancer of the Ovary (DISCOVAR)

Ovarian Cancer | Peritoneal Metastases

United Kingdom

Clinical Trials Sponsored by Imperial College Healthcare Trust, St Mary's Hospital

Sponsors and Collaborators

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