Clinical Trials Sponsored by Institute for Medical Research and Occupational Health

Total 2043 results

Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); University of Chicago; University... and other collaborators

Terminated

CleanUP IPF for the Pulmonary Trials Cooperative (CleanUp-IPF)

Idiopathic Pulmonary Fibrosis

United States
Children's National Research Institute
Patient-Centered Outcomes Research Institute; Eunice Kennedy Shriver National... and other collaborators

Completed

PCORI Urea Cycle Disorder Study

Urea Cycle Disorders

United States
Arbor Research Collaborative for Health
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Washington... and other collaborators

Recruiting

LURN: Urinary Urgency Phenotyping Protocol

Lower Urinary Tract Symptoms

United States
Parc Sanitari Pere Virgili
Consorci Sanitari Integral; Vall d'Hebron Institute of Research; Health and Ageing... and other collaborators

Recruiting

IMAGINE Study Protocol (IMAGINE)

Patients (>=60 Years Old) Suffering From Mild-moderate Stroke (Ischemic or Hemorrhagic, Stroke Severity Assessed by NIHSS <16 Points)

Spain, Sweden
Arbor Research Collaborative for Health
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Washington... and other collaborators

Completed

Symptoms of Lower Urinary Tract Dysfunction Protocol 2/Recall Study

Lower Urinary Tract Symptoms

United States
Karolinska Institutet
The Swedish Research Council; University of California, San Francisco; Swedish... and other collaborators

Completed

Inflammation and Brain Function - Pilot Study

Sickness Behavior
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); University of Michigan; Duke... and other collaborators

Completed

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 2) (CAPTURE)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); University of Michigan; Duke... and other collaborators

Completed

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 1) (CAPTURE)

Chronic Obstructive Pulmonary Disease (COPD)

United States
VTT Technical Research Centre of Finland
Social Insurance Institution, Finland; Finnish Institute for Health and Welfare and other collaborators

Completed

Pharmacogenomics of Antithrombotic Drugs -a Register Linkage Study With National Registries and Biobanks in Finland

Individuals With a Disease of Cardiovascular System

Finland
Arbor Research Collaborative for Health
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Washington... and other collaborators

Completed

Symptoms of Lower Urinary Tract Dysfunction Phenotyping Study

Lower Urinary Tract Symptoms

United States
University of California, San Francisco
Harvard Medical School (HMS and HSDM); National Institute of Allergy and Infectious... and other collaborators

Recruiting

Rapid Research in Diagnostics Development for TB Network (R2D2TB Network)

Tuberculosis

South Africa, Uganda, Georgia, India, Philippines, Vietnam
University of Ibadan
Shin Poong Pharm Co Ltd 161 yoksam-ro, Gangnam-Gu Seoul 135-925, Korea; Institute...

Completed

Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-Lumefantrine

Plasmodium Falciparum Malaria | Uncomplicated Malaria | Malaria Fever

Nigeria
Georgetown University
Memorial Sloan Kettering Cancer Center; City of Hope Medical Center; Indiana... and other collaborators

Recruiting

Older Breast Cancer Patients: Risk for Cognitive Decline (TLC)

Cognitive Decline | Cancer, Breast | Age-related Cognitive Decline

United States
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); University of Michigan; Duke... and other collaborators

Completed

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3) (CAPTURE)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Johns Hopkins Bloomberg School of Public Health
United States Agency for International Development (USAID); Bill and Melinda... and other collaborators

Completed

Single-dose Postpartum Vitamin A Supplementation of Mothers and Neonates (ZVITAMBO)

HIV | Vitamin A Deficiency
Preventive Medicine Research Institute
Harvard Medical School (HMS and HSDM); University of California, San Diego; The... and other collaborators

Active, not recruiting

Can Lifestyle Changes Reverse Early-Stage Alzheimer's Disease

Alzheimer Disease

United States
Karolinska Institutet
The Swedish Research Council; University of California, San Francisco; Swedish... and other collaborators

Completed

Inflammation and Brain Function - Main Study

Sickness Behavior
Jason Wilken
Minneapolis Veterans Affairs Medical Center; Johns Hopkins Bloomberg School... and other collaborators

Completed

Ankle Foot Orthosis Comparative Effect (AFOCE)

Foot Injuries and Disorders

United States
Leiden University Medical Center
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Netherlands... and other collaborators

Completed

Implementation Study With Decision Support Based on Data

Urinary Tract Infections

Netherlands
St. Louis University
Johns Hopkins University; Massachusetts General Hospital; Beth Israel Deaconess... and other collaborators

Recruiting

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

Giant Cell Tumor of Bone

United States, Canada, India
Duke-NUS Graduate Medical School
Khoo Teck Puat Hospital; Singapore General Hospital; Tan Tock Seng Hospital; Institute... and other collaborators

Terminated

Levothyroxine for Non-Alcoholic Fatty Liver Disease (NAFLD)

Diabetes Mellitus, Type 2 | Non-Alcoholic Fatty Liver Disease
International AIDS Vaccine Initiative
University of Cape Town Lung Institute; European and Developing Countries Clinical... and other collaborators

Active, not recruiting

Study to Evaluate H56:IC31 in Preventing Rate of TB Recurrence

Tuberculosis, Pulmonary

South Africa, Tanzania
Wroclaw Medical University
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; University of Valencia and other collaborators

Unknown

FOCUS- Frailty Management Optimization Through EIP AHA Commitments and Utilization of Stakeholders Input (FOCUS-WMU)

Frailty

Poland
Aryn Knight
The University of Texas Health Science Center, Houston; Baylor College of Medicine and other collaborators

Withdrawn

Umbilical Cord Blood in the Treatment of Stroke in Children. (Pedi Stroke)

Arterial Ischemic Stroke (AIS) in Children

United States
Klaus Reither
Radboud University Medical Center; Charite University, Berlin, Germany; University... and other collaborators

Completed

Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis (TB TRIAGE+)

Covid-19 | HIV | Pulmonary Tuberculosis | Tuberculosis Diagnosis

Lesotho, South Africa
RAND
National Institute of Mental Health (NIMH); University of Pittsburgh; Boston... and other collaborators

Active, not recruiting

Collaboration Leading to Addiction Treatment and Recovery From Other Stresses (CLARO)

Depression | Addiction | Opioid-use Disorder | Post-traumatic Stress Disorder

United States
RAND
National Institute of Mental Health (NIMH); University of Pittsburgh; Boston... and other collaborators

Active, not recruiting

Competitive Revision for CLARO: Collaboration Leading to Addiction Treatment and Recovery From Other Stresses

Depression | Suicidal Ideation | Addiction | Post Traumatic Stress Disorder | Opioid-use Disorder

United States
SingHealth Polyclinics
National University Hospital, Singapore; Khoo Teck Puat Hospital; Singapore General... and other collaborators

Terminated

Insulin Resistance and Mild Cognitive Impairment (IRMCI) Study (IRMCI)

Diabetes Mellitus, Type 2 | Insulin Resistance | Mild Cognitive Impairment

Singapore
Centre for Addiction and Mental Health
LOFT Community Services; Institute for Clinical Evaluative Sciences; The Ontario... and other collaborators

Active, not recruiting

Integrated Collaborative Care Teams for Youth With Mental Health and/or Addiction Challenges (YouthCan IMPACT)

Mental Disorders | Addiction

Canada
East Bay Institute for Research and Education
University of California, Davis; University of California, Irvine; Kaiser Permanente and other collaborators

Completed

Effect of ERCP Mechanical Simulator (EMS) Practice on Endoscopic Retrograde Cholangiopancreatography (ERCP) Training (ERCP)

Training

United States
University Hospital, Aker
University of Oslo; AstraZeneca; Norwegian University of Science and Technology; Diakonhjemmet Hospital and other collaborators

Completed

Treatment of Schizophrenia With an Omega-3 Fatty Acid (EPA) and Antioxidants

Psychotic Disorders | Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorders

Norway
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Training Local Leaders to Prevent and Reduce Domestic Violence Evidence From Peru (LIA)

Domestic Violence

Peru
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601) (SCURT)

Sickle Cell Disease

United States
The University of Queensland
University of California, Los Angeles; Monash University; University of Sydney; Griffith University and other collaborators

Active, not recruiting

Gonorrhoea Resistance Assessment by Nucleic Acid Detection (GRANDII) (GRANDII)

Gonorrhea | Antimicrobial Stewardship | Drug Resistance, Microbial

Australia
University of Vermont
Dartmouth-Hitchcock Medical Center; Dartmouth College; MaineHealth; MaineGeneral... and other collaborators

Completed

A Community Health Worker Program to Support Rural Older Adults

Cognitive Impairment | Depressive Symptoms | Frail Elderly | Mobility Limitation

United States
University of Cape Town
Radboud University Medical Center; University of Stellenbosch; Foundation for... and other collaborators

Recruiting

Evaluating the Impact of Computer-assisted X-ray Diagnosis and Other Triage Tools to Optimise Xpert Orientated Community-based Active Case Finding for TB and COVID-19

HIV Infections | COVID-19 | Tuberculosis

South Africa, Zambia, Zimbabwe
Brigham and Women's Hospital
Patient-Centered Outcomes Research Institute; Massachusetts General Hospital; University of Missouri-Columbia and other collaborators

Recruiting

BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes (BESTMED)

Diabetes Mellitus, Type 2

United States
Jaeb Center for Health Research
University of Colorado, Denver; National Institute of Diabetes and Digestive... and other collaborators

Completed

Day and Night Closed-loop in Young People With Type 1 Diabetes (DAN05)

Glucose Metabolism Disorders | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1

United Kingdom, United States
Amsterdam UMC, location VUmc
Erasmus Medical Center; ZonMw: The Netherlands Organisation for Health Research... and other collaborators

Recruiting

Percutaneous Transforaminal Endoscopic Discectomy vs. Open Microdiscectomy for Lumbar Disc Herniation (PTED-study)

Lumbar Disk Herniation

Netherlands
Seattle Institute for Biomedical and Clinical Research
University of Colorado, Denver; Yale University; VA Connecticut Healthcare System and other collaborators

Active, not recruiting

High-quality COPD Care for People With Immune Dysfunction Through Proactive E-consults (ACHIEVE)

HIV/AIDS | COPD

United States
Helen Minnis
King's College London; National Institute for Health Research, United Kingdom; NHS Greater Glasgow and Clyde and other collaborators

Active, not recruiting

Effectiveness and Cost-effectiveness of the New Orleans Intervention Model for Infant Mental Health (BeST?-)

Mental Health | Maltreatment

United Kingdom
The Methodist Hospital Research Institute
Massachusetts General Hospital; The Center for Clinical and Translational Sciences... and other collaborators

Active, not recruiting

T-regulatory Cells in ALS (Tregs in ALS)

ALS (Amyotrophic Lateral Sclerosis)

United States
National Institute of Allergy and Infectious Diseases...
London School of Hygiene and Tropical Medicine; Institut National de la Santé... and other collaborators

Active, not recruiting

Partnership for Research on Ebola VACcinations (PREVAC)

Ebola Virus Disease

Guinea, Liberia, Mali, Sierra Leone
The George Institute
National Health and Medical Research Council, Australia; Medical University... and other collaborators

Recruiting

The RAFT ECT Study (RAFT-ECT)

Major Depressive Episode

United States, Australia
University of North Carolina, Chapel Hill
Patient-Centered Outcomes Research Institute; National Institute of Arthritis... and other collaborators

Completed

Low Dose Oral Methotrexate in Pediatric Crohn's Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy (COMBINE)

Pediatric Crohn's Disease

United States
University of Washington
University of Colorado, Denver; Massachusetts General Hospital; Mayo Clinic; Oregon... and other collaborators

Completed

Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial) (LESS)

Low Back Pain | Spinal Stenosis

United States
Médecins Sans Frontières, France
Harvard Medical School (HMS and HSDM); Institute of Tropical Medicine, Belgium and other collaborators

Active, not recruiting

Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q) (endTB-Q)

Bacterial Infections | Gram-Positive Bacterial Infections | Tuberculosis | Tuberculosis, Multidrug-Resistant | Pulmonary Tuberculoses | Mycobacterial Infections

Vietnam, Pakistan, India, Kazakhstan, Lesotho, Peru
University of Crete
Aristotle University Of Thessaloniki; Ottawa Heart Institute Research Corporation and other collaborators

Unknown

Tobacco Treatment TrAining Network in Greece & Cyprus (TiTAN)

Tobacco Use

Greece
Schön Klinik Berchtesgadener Land
GlaxoSmithKline GmbH & Co. KG (Munich, Germany); Coordinating Center for Clinical... and other collaborators

Active, not recruiting

Predictors of Acute Exacerbation in Patients With COPD - an Observational Study (PACE)

Chronic Obstructive Pulmonary Disease | COPD | COPD Exacerbation | COPD Exacerbation Acute

Germany
University of British Columbia
University of Pennsylvania; Wuhan University; Canadian Institutes of Health Research... and other collaborators

Unknown

Host Response Mediators in Coronavirus (COVID-19) Infection (ARBS CORONA I)

COVID-19 | SARS-CoV2

Canada

Clinical Trials Sponsored by Institute for Medical Research and Occupational Health

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