Clinical Trials Sponsored by Motif Bio

Total 2354 results

Sao Thai Duong Joint Stock Company
Big Leap Clinical Research Joint Stock Company

Completed

Safety and Efficacy of KOVIR in the Combination Regimen With Background Treatment in COVID-19 Patients (KOVIR) (KOVIR)

COVID-19

Vietnam
Hospital de Clinicas de Porto Alegre
Federal University of Rio Grande do Sul

Completed

Teleconsultation in Counter-reference Between Tertiary and Primary Care for Patients With Benign Prostatic Hyperplasia

Prostatic Hyperplasia

Brazil
Hospital de Clinicas de Porto Alegre
Federal University of Rio Grande do Sul

Completed

Urethral Stricture: A Comparison Between Jugal or Labial Graft Urethroplasty

Urethral Stricture
Federal University of Rio Grande do Sul
Aline Nogueira Haas; Flávia Gomes Martinez

Active, not recruiting

Effects of Different Physical Therapies and Dance in People With Parkinson's Disease

Parkinson Disease | Parkinson Disease 10

Brazil
Seoul National University Hospital
Boston Scientific Korea Co. Ltd; Dio; Terumo Corporation; Abbott

Unknown

Harmonizing Optimal Strategy for Treatment of Coronary Artery Diseases Trial - Comparison of REDUCTION of PrasugrEl Dose & POLYmer TECHnology in ACS Patients (HOST REDUCE POLYTECH RCT Trial)

Acute Coronary Syndrome

Korea, Republic of
Hospital de Clinicas de Porto Alegre
Federal University of Rio Grande do Sul

Unknown

Technology for Innovative Monitoring of Cardiovascular Prevention: a RCT (TIM)

Prehypertension | Blood Pressure, High

Brazil
Henk Bilo, MD
University Medical Center Groningen; Isala

Completed

Large Scale Demonstrator, Webportal Diabetes (LSD)

Diabetes Mellitus Type 2

Netherlands
Ana Elizabeth Prado Lima Figueiredo

Completed

Study to Determine Appropriate Nurse: Patient Ratios in Peritoneal Dialysis Programs

Chronic Renal Failure

Brazil
Hospital de Clinicas de Porto Alegre
Federal University of Rio Grande do Sul

Completed

Intervention in the Management of Post-high Tuberculosis Hospital Through Educational Strategy and Oversight Distance

Pulmonary Tuberculosis | Extra Pulmonary Tuberculosis

Brazil
Imam Abdulrahman Bin Faisal University
King Abdulaziz University; Ministry of Health, Saudi Arabia

Completed

Saudi Outcomes of ECMO-treated MERS-CoV Patients

Refractory Hypoxemia | MERS-CoV Infection

Saudi Arabia
Federal University of Rio Grande do Sul
Hospital de Clinicas de Porto Alegre

Completed

IMT in Ventilatory Muscle Metaboreflex in COPD

Chronic Obstructive Pulmonary Disease

Brazil
Polisa - Biopolímeros para Saúde
Rio de Janeiro State University; Universidade Federal de Pernambuco

Completed

Study Comparing the Polyurethane Films and Sugarcane Biopolymer Used as Dressings

Rupture | Surgery | Cesarean Section | Wound

Brazil
Hospital de Clinicas de Porto Alegre
Federal University of Rio Grande do Sul

Completed

Aquatic and Land Physical Training Effects on Cardiometabolic Risk Factors in Adolescents With Overweight and Obesity

Obesity | Overweight
Instituto de Cardiologia do Rio Grande do Sul
Quaker Oats Company; CNPq Universal

Unknown

Impact of Consumption of Oats in Lipid Profile of Children and Adolescents With Dyslipidemia

Atherosclerosis | Hypercholesterolemia

Brazil
Hospital do Olho Rio Preto
Faculty of Medicine of Ribeirão Preto (FMRP-USP)

Completed

Prevalence of Diabetic Retinopathy in São José do Rio Preto-SP-Brazil

Diabetic Retinopathy

Brazil
Jianbin Bi

Not yet recruiting

Rezvilutamide Plus Abiraterone for Metastatic Hormone-sensitive Prostate Cancer (RASTOM)

Metastatic Hormone-Sensitive Prostate Cancer
University of Urbino "Carlo Bo"
University of Pavia

Not yet recruiting

Effects of Melissa Extract on Sleep Characteristics

Quality of Life | Sleep Disorder | Anxiety

Italy
IO Biotech
Merck Sharp & Dohme LLC; Theradex; Almac

Recruiting

Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors

Melanoma | Squamous Cell Carcinoma of Head and Neck

United States, Australia, Denmark, Spain, France, Germany
IO Biotech
Merck Sharp & Dohme LLC; Syneos Health

Active, not recruiting

IO102-IO103 in Combination With Pembrolizumab Versus Pembrolizumab Alone in Advanced Melanoma (IOB-013 / KN-D18)

Metastatic Melanoma | Unresectable Melanoma

Hungary, Spain, United Kingdom, Australia, France, Italy, United States, Denmark, Germany, Israel, Czechia, Belgium, Netherlands, Turkey, Poland, South Africa
Yu Bo
Massachusetts General Hospital

Completed

Paradigm Shift in the Treatment of Patients With ACS

Acute Coronary Syndrome

China
University College Dublin
Irish Cancer Society; Big Health Ltd.; Research Electronic Data Capture (REDCap)

Not yet recruiting

The Sleepio After Cancer Study (SACS)

Cancer | Insomnia

Ireland
Lawrence Feldman, MD
Merck Sharp & Dohme LLC; HiberCell, Inc.

Active, not recruiting

Pembrolizumab + Imprime PGG for Metastatic Non-small Cell Lung Cancer After Progression on First-Line Therapy: Big Ten Cancer Research Consortium BTCRC-LUN15-017

Non-Small Cell Lung Cancer

United States
D'Or Institute for Research and Education
Rio de Janeiro State Research Supporting Foundation (FAPERJ)

Completed

Family and Patient Outcomes After Pediatric Intensive Care (FOREVER) (FOREVER)

Depression | Quality of Life | Stress Disorders, Post-Traumatic | Anxiety | Satisfaction, Patient | Post-Intensive Care Syndrome

Brazil
Universidade Federal do Rio de Janeiro
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.

Completed

Effect of a Propolis Tablet on the Saliva and the Amount of Adolescent Dental Plaque Microbes

Dental Plaque

Brazil
Universidade Federal do Rio Grande do Norte
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Unknown

Motor Learning of Stroke Patients in Virtual Environments

Stroke | Stroke Sequelae

Brazil
Instituto de Cardiologia do Rio Grande do Sul
Hospital de Clinicas de Porto Alegre

Unknown

Anti-Inflammatory Drug and Endothelial Function (HOLD)

Cardiovascular Diseases | Coronary Artery Disease | Atherosclerosis | Sleep Apnea | Endothelial Dysfunction

Brazil
AIO-Studien-gGmbH
Amgen; Assign Data Management and Biostatistics GmbH; Assign Clinical Research...

Terminated

Cisplatin and 5-FU +/- Panitumumab for Patients With Nonresectable,Advanced or Metastatic Esophageal Squamous Cell Cancer (POWER)

Esophageal Squamous Cell Cancer

Germany
Patri-cia Angelica de Miranda Silva Nogueira

Completed

CPAP Versus Bi-level in Chronic Heart Failure (CHF)

Heart Failure
Rio de Janeiro State University
Laboratory for Clinical and Experimental Research on Vascular Biology

Completed

Acute and Short-term Chronic Effects of Galvus (Vildagliptin) in Diabetes Type 2 Obese Women

1- Microvascular Function | 2-oxidative Stress | 3-inflammation

Brazil
Universidade Federal do Rio Grande do Norte
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Gait Training With Cognitive Tasks in Parkinson's Disease

Parkinson's Disease

Brazil
Cleber Ferraresi
Universidade Federal do Rio Grande do Norte

Completed

Use of Low-level Laser Therapy (808nm) to Muscle Fatigue Resistance

Healthy

Brazil
Instituto de Cardiologia do Rio Grande do Sul
Instituto de Cardiologia de Santa Catarina

Unknown

The Effects of mETHotrexate Therapy on ST Segment Elevation MYocardial InfarctionS (TETHYS Trial) (TETHYS)

Myocardial Infarction

Brazil
Hospital Ernesto Dornelles
Federal University of Rio Grande do Sul; Hospital Moinhos de Vento

Unknown

Lung Ultrasound Assisting Weaning in Difficult-to-wean Patients (WeanUS)

Difficult-to-wean Adult Patients

Brazil
Sao Jose do Rio Preto Medical School
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Microbiological Keratitis in a Countryside City of Brazil

Keratitis

Brazil
PT Bio Farma
Sinovac Life Sciences Co., Ltd.; Faculty of Medicine Universitas Padjadjaran; National Intitute of Health Research and Development, Ministry of Health Republic of Indonesia

Completed

Efficacy, Safety and Immunogenicity Study of SARS-CoV-2 Inactivated Vaccine (COVID-19)

SARS-CoV2 Infection

Indonesia
Bio-Sensing Solutions S.L. (DyCare)
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau; Centre...

Recruiting

Validation of a Digital Platform for Functional Respiratory Rehabilitation (ReHub)

COPD

Spain
International Centre for Diarrhoeal Disease Research...
Bill and Melinda Gates Foundation; Centers for Disease Control and Prevention; PA... and other collaborators

Completed

Clinical Trial of Novel OPV2 Vaccine

Poliomyelitis

Bangladesh
A.O. Ospedale Papa Giovanni XXIII
Aferetica - Italy (BO)

Terminated

Convalescent Antibodies Infusion in Critically Ill COVID 19 Patients

Coronavirus Infection | Pneumonia, Ventilator-Associated

Italy
University of Urbino "Carlo Bo"
University of Padova

Completed

Relationship-based Care Model in Pediatrics

Nurse-Patient Relations | Depression, Anxiety
Federal University of Rio Grande do Sul
Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, Brazil; Conselho... and other collaborators

Unknown

Partial Removal of Caries Dentines (PRCD)

Dental Caries

Brazil
Instituto Nacional de Traumatologia e Ortopedia
Rio de Janeiro State Research Supporting Foundation (FAPERJ)

Not yet recruiting

Knee Osteoarthritis Treatment With Platelet-rich Plasma

Osteoarthritis, Knee

Brazil
Sao Thai Duong Joint Stock Company
Big Leap Clinical Research Support Joint Stock Company

Recruiting

To Evaluate the Efficacy and Safety of Shampoo TD03 and TD07 in Scalp Diseases (TD0307)

Scalp Dermatitis

Vietnam
Pontificia Universidade Católica do Rio Grande...
ITI International Team for Implantology, Switzerland

Completed

Short Implants Supporting Single Crowns in the Posterior Region

Quality of Life | Dental Implants | Dental Prosthesis

Brazil
AIO-Studien-gGmbH
Bayer; Institut für Klinisch-Onkologische Forschung (IKF) am Krankenhaus Nordwest...

Completed

Regorafenib in Combination With TAS-102 in Subjects With Metastatic Colorectal Cancer Who Have Progressed After Standard Therapy (REMETY)

Pretreated Metastatic Colorectal Cancer

Germany
Hospital de Clinicas de Porto Alegre
UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL (UFRGS)

Completed

Positive Expiratory Pressure With Blow-bottle Device Versus EPAP After Postoperative Cardiac Surgery

Thoracic Surgery

Brazil
Federal University of Rio Grande do Sul
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Unknown

Metabolic Syndrome and Periodontitis

Metabolic Syndrome | Inflammatory Response | Periodontal Disease

Brazil
Singapore General Hospital
Shanghai Yueyang Integrated Medicine Hospital; Singapore Bao Zhong Tang TCM...

Completed

Traditional Chinese Medicine in the Supportive Management of Anaemic and Cytopenic (Leukopenia, Thrombocytopenia) Haematological Disorders

Myelodysplastic Syndrome (MDS) | Myelofibrosis (MF) | Thalassemia Intermedia | Aplastic Anaemia (AA)

Singapore
AIO-Studien-gGmbH
Universitätsklinikum Hamburg-Eppendorf; Merck Serono GmbH, Germany; Pierre Fabre...

Recruiting

Neoadjuvant Encorafenib, Binimetinib and Cetuximab for Patients With BRAF V600E Mutated/pMMR Localized Colorectal Cancer (NeoBRAF)

Colorectal Cancer | Colon Cancer | BRAF V600 Mutation | BRAF V600E | Localized Cancer

Germany
Laura Alice Santos Oliveira
Federal Institute of Rio de Janeiro

Enrolling by invitation

Trans-spinal Electrical Stimulation in Individuals With Spinocerebellar Ataxia

Gait Ataxia | Postural Balance | SCA

Brazil
Universidade Federal do Rio de Janeiro
CNPq - National Council for Scientific and Technological Development

Completed

Visual Oral Examination for Early Detection of Oral Cancer in High-Risk Individuals

Mouth Neoplasms

Brazil

Clinical Trials Sponsored by Motif Bio

Sponsors and Collaborators

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