Clinical Trials Sponsored by NIHR Clinical Research Facility, University Hospital Southampton NHS Foundation Trust

Total 81 results

University Hospital Southampton NHS Foundation...
NIHR Southampton Biomedical Research Centre

Withdrawn

Fortified Foods in Older Inpatients

Malnutrition | Dementia | Frail Elderly Syndrome | Aging

United Kingdom
Lancashire Teaching Hospitals NHS Foundation Trust
NIHR Lancashire Clinical Research Facility

Completed

Low Dose Lung Radiotherapy to Treat COVID-19 Pneumonia

Covid19

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
NIHR Exeter Clinical Research Facility

Completed

Glucose Response, Excursions And Treatment (GREAT) Study (GREAT)

Type 2 Diabetes

United Kingdom
NIHR Exeter Clinical Research Facility
Torbay and South Devon NHS Foundation Trust

Completed

Nitrate, Chronic Obstructive Pulmonary Disease (COPD) and Exercise

COPD

United Kingdom
University Hospital Southampton NHS Foundation...
Medical Research Council; University of Southampton

Completed

Women's Responses to Adjusted Product Placement and Its Effects on Diet - 1 (WRAPPED1) (WRAPPED1)

Diet Modification
University Hospital Southampton NHS Foundation...
Asthma Allergy & Inflammation Research Trust

Recruiting

Severe Asthma Covid Vaccine Response Study (SHINE)

Coronavirus Antibody Levels

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
University of Exeter; NIHR Exeter Clinical Research Facility

Completed

The Genetics of Adipose Tissue Function and Its Link to Type 2 Diabetes and Heart Disease (FATFUNgenes)

Diabetes Mellitus

United Kingdom
University Hospital Southampton NHS Foundation...
Warwick University Clinical Trials Unit

Not yet recruiting

Ventricular Fibrillation Following Out-of-hospital Cardiac Arrest

Ventricular Fibrillation | Cardiac Arrest, Out-Of-Hospital

United Kingdom
University Hospital Southampton NHS Foundation...
AstraZeneca; Cancer Research UK

Completed

Open Label Phase I/Randomised,Double Blind Phase II Study in mCRPC of AZD5363 In Combination With DP Chemotherapy (ProCAID)

Prostate Cancer

United Kingdom
University Hospital Southampton NHS Foundation...
Cancer Research UK; The Christie NHS Foundation Trust; Celldex Therapeutics; Oxford... and other collaborators

Active, not recruiting

A Combination of Rituximab and Varlilumab Immunotherapy in Patients With B-cell Lymphoma (RiVa)

B Cell Lymphoma

United Kingdom
Yeovil District Hospital NHS Foundation Trust
University of Southampton; University Hospital Southampton NHS Foundation Trust and other collaborators

Unknown

Frailty and Sarcopenia Outcomes in Emergency General Surgery (FrOGS)

Emergencies | Frail Elderly Syndrome | Sarcopenia | Surgery

United Kingdom
University of Southampton
NIHR Clinical Research Facility, University Hospital Southampton NHS Foundation... and other collaborators

Terminated

High-Dose Melphalan With or Without Radiolabeled Monoclonal Antibody in Treating Patients With Multiple Myeloma Undergoing an Autologous Stem Cell Transplant (AntiCD-66)

Multiple Myeloma and Plasma Cell Neoplasm

United Kingdom
University of Southampton
University Hospital Southampton NHS Foundation Trust; National Institute for... and other collaborators

Completed

Development and Pilot Evaluation of a Web-supported Programme of Constraint Induced Therapy Following Stroke (LifeCIT)

Stroke

United Kingdom
University Hospital Southampton NHS Foundation...
Roche Pharma AG; Cancer Research UK

Recruiting

Atezolizumab Immunotherapy, in Immunotherapy Naive Patients With Urinary Tract Squamous Cell Carcinoma (UTSCC). (AURORA)

Squamous Cell Carcinoma | Urinary Tract Cancer

United Kingdom
Papworth Hospital NHS Foundation Trust
King's College Hospital NHS Trust; The Leeds Teaching Hospitals NHS Trust; University... and other collaborators

Completed

Home Monitoring to Predict Exacerbation in Cystic Fibrosis (SmartCare)

Cystic Fibrosis

United Kingdom
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Completed

A Feasibility Study of Early Mobilisation Programmes in Critical Care (EMPRESS)

Critical Illness

United Kingdom
University of Cambridge
The Leeds Teaching Hospitals NHS Trust; Cambridge University Hospitals NHS... and other collaborators

Active, not recruiting

Closed Loop From Onset in Type 1 Diabetes (CLOuD)

Diabetes Mellitus | Type 1 Diabetes

United Kingdom
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Recruiting

Eye Movement Desensitisation and Reprocessing (EMDR) to Improve Mental Health Following Intensive Care Admission (EMERALD)

Critical Illness | Post Traumatic Stress Disorder | Depression, Anxiety | Eye Movement Desensitisation and Reprocessing

United Kingdom
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Completed

Investigation of Synbiotic Treatment in NAFLD (INSYTE)

Non-Alcoholic Fatty Liver Disease

United Kingdom
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Completed

Treatment of Non Alcoholic Fatty Liver Disease With n-3 Fatty Acids (WELCOME)

Non-Alcoholic Fatty Liver Disease

United Kingdom
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Completed

Grip Strength Routine Implementation (GRImP)

Frail Elderly, Inpatients

United Kingdom
University of Oxford
King's College Hospital NHS Trust; Nottingham University Hospitals NHS Trust; Guy's and St Thomas' NHS Foundation Trust and other collaborators

Enrolling by invitation

Echocardiography: Value and Accuracy at REst and STress (EVAREST)

Coronary Artery Disease | Angina Pectoris | Ischaemic Heart Disease
University of Southampton
BlueWind Medical; University Hospital Southampton NHS Foundation Trust; National...

Withdrawn

Urinary Catheter 'Fill and Flush' Valve: Safety, Effectiveness, Acceptability and Feasibility Trial

Indwelling Urinary Catheter Users

United Kingdom
University of Southampton
University Hospital Southampton NHS Foundation Trust; University of Birmingham and other collaborators

Completed

A Study Into Airways Disease Case Finding and Management (ASSIST)

Asthma | COPD

United Kingdom
Owlstone Ltd
University College, London; University of Athens; University Hospital, Ghent; University... and other collaborators

Completed

Lung Cancer Indicator Detection (LuCID)

Lung Cancer

Germany, United Kingdom, Belgium, Italy
University Hospital Southampton NHS Foundation...
Medical Research Council; National Institute for Health Research, United Kingdom

Completed

The Southampton Mealtime Assistance Roll-out Trial (SMART)

Volunteer Mealtime Assistants

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
University College, London; University of Southampton; University Hospital Southampton... and other collaborators

Completed

Conservative Versus Liberal Oxygenation Targets in Critically Ill Children (Oxy-PICU)

Hypoxia | Pediatric ALL | Critical Care

United Kingdom
University Hospital Southampton NHS Foundation...
Cancer Research UK; IntraOp Medical Corporation; PLANETS Cancer Charity

Recruiting

Intraoperative Electron Radiotherapy in Rectal Cancer - A Feasibility Trial (ELECTRA)

Locally Advanced Rectal Cancer | Locally Recurrent Rectal Cancer

United Kingdom
University of Southampton
University of Leeds; Newcastle-upon-Tyne Hospitals NHS Trust; National Institute... and other collaborators

Not yet recruiting

Promoting Increased Physical Activity in Hospitalised Older Adults (PIVOT)

Hospital-associated Deconditioning
Imperial College London
University College London Hospitals; Northern Care Alliance NHS Foundation... and other collaborators

Recruiting

Augmented Response of Volatile Biomarkers in Assessment of Oesophagogastric Cancer (AROMA 1 / BIORESOURCE)

Gastric Cancer | Oesophageal Cancer | Microbiome | Volatile Organic Compounds | Transcriptomics | Microbioata | Breath Analysis | Volatalomics | Metabonomics/Lipidomics | Microbiome Analysis

United Kingdom
University College, London
Royal Free Hospital NHS Foundation Trust; University Hospital Southampton NHS... and other collaborators

Completed

Targeted OXYgen Therapy in Critical Illness (TOXYC)

Critical Illness | Respiratory Failure

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Nottingham University Hospitals NHS Trust; Barts & The London NHS Trust and other collaborators

Recruiting

The BARCODE 2 Study - The Use of Genetic Profiling to Guide Prostate Cancer Treatment (BARCODE2)

Hormone Refractory Prostate Cancer

United Kingdom
University of East Anglia
The Norfolk and Norwich University Hospitals NHS Foundation Trust; The Quadram...

Not yet recruiting

Effects of Vitamin C on Skeletal Muscle (VICS)

Healthy

United Kingdom
University Hospital Southampton NHS Foundation...
Medical Research Council; University of Southampton; National Institute for Health... and other collaborators

Active, not recruiting

Women's Responses to Adjusted Product Placement and Its Effects on Diet - 2 (WRAPPED2)

Diet Modification

United Kingdom
University Hospital Southampton NHS Foundation...
Imperial College Healthcare NHS Trust; Royal Devon and Exeter NHS Foundation... and other collaborators

Completed

WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular Electroporation (WIN)

Leukaemia (Acute) | Leukaemia (Chronic) | Leukaemia (Acute Myeloid) | Leukaemia (Acute Lymphoblastic) | Leukaemia (Acute Promyelocytic)

United Kingdom
Queen's University, Belfast
Mayo Clinic; University Hospital Southampton NHS Foundation Trust; University... and other collaborators

Completed

Myeloproliferative Neoplasms: an In-depth Case-control Study (MOSAICC)

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia

United Kingdom
University Hospital Southampton NHS Foundation...
Bristol-Myers Squibb; Cancer Research UK; Institute of Cancer Research, United...

Completed

The Addition of Ipilimumab to Carboplatin and Etoposide Chemotherapy for Extensive Stage Small Cell Lung Cancer (ICE)

Extensive Stage Small Cell Lung Cancer

United Kingdom
Queen's University, Belfast
Medical Research Council; Belfast Health and Social Care Trust; NHS Lothian; University... and other collaborators

Completed

Clinimetric Properties of Outcome Measures in Bronchiectasis in the UK

Bronchiectasis

United Kingdom
Bournemouth University
University of Southampton; National Institute for Health Research, United Kingdom and other collaborators

Completed

The TACIT Trial: TAi ChI for People With demenTia (TACIT)

Dementia | Accidental Falls

United Kingdom
University of Southampton
University Hospital Southampton NHS Foundation Trust; National Institute for... and other collaborators

Recruiting

Benchmarking Integrated Care for People Living With Huntington's Disease in England (Integrate-HD)

Huntington Disease

United Kingdom
Manchester University NHS Foundation Trust
University College, London; University Hospital Southampton NHS Foundation... and other collaborators

Recruiting

Comparing the Side-lying Sleep Positioning to Back-lying in Infants With Cleft Palate (SLUMBRS2)

Obstructive Sleep Apnea | Cleft Palate

United Kingdom
Cardiff and Vale University Health Board
The Leeds Teaching Hospitals NHS Trust; University of Leeds; University Hospital... and other collaborators

Active, not recruiting

Pathway of Low Anterior Resection Syndrome Relief After Surgery: a Feasibility Study (POLARiS)

Low Anterior Resection Syndrome

United Kingdom
University Hospital Southampton NHS Foundation...
Novartis; Boehringer Ingelheim; National Institutes of Health (NIH); National Institute... and other collaborators

Active, not recruiting

Wessex Asthma Cohort of Difficult Asthma (WATCH)

Asthma

United Kingdom
Maastricht University Medical Center
King's College Hospital NHS Trust; Oslo University Hospital; Federico II University and other collaborators

Active, not recruiting

ORANGE SEGMENTS: Open Versus Laparoscopic Parenchymal Preserving Postero-Superior Liver Segment Resection

Liver Surgery

United Kingdom, Netherlands, Belgium, Italy, Norway, Russian Federation
University of Sheffield
Sheffield Teaching Hospitals NHS Foundation Trust; South Yorkshire and Bassetlaw...

Unknown

Exploring Advanced Clinical Practitioner's Experience Developing Clinical Competence and Opinions on Role Identity

Nurse's Role | ACP | Development, Consensus

United Kingdom
University College, London
London School of Hygiene and Tropical Medicine; King's College London; Odense... and other collaborators

Completed

Effect of Remote Ischaemic Conditioning on Clinical Outcomes in STEMI Patients Undergoing PPCI (CONDI2/ERIC-PPCI)

Myocardial Reperfusion Injury | STEMI

Denmark, United Kingdom, Spain, Serbia
Imperial College London
University Hospital Southampton NHS Foundation Trust; National Institute for... and other collaborators

Unknown

EndoBarrier TM Gastrointestinal Liner Diabetes Trial (EndoBarrier)

Diabetes | Overweight and Obesity

United Kingdom
Diurnal Limited
Sheffield Teaching Hospitals NHS Foundation Trust; Manchester University NHS... and other collaborators

Completed

Study to Compare DITEST to Testosterone Undecanoate in Adult Men With Hypogonadism

Male Hypogonadism

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
University of Nottingham; Imperial College London; University College, London; Cambridge... and other collaborators

Not yet recruiting

BEARS Training Package to Maximise Hearing Abilities in Older Children and Teenagers With Bilateral Cochlear Implants (BEARS)

Hearing Loss | Deafness | Hearing Loss, Sensorineural | Hearing Impaired Children and Adolescents
University Hospital Birmingham NHS Foundation Trust
University of Birmingham; National Institute for Health Research, United Kingdom and other collaborators

Unknown

Can Vitamin D Supplementation in People With Crohn's Disease Improve Symptoms as an Adjunct Therapy? (D-CODE)

Vitamin D Deficiency | Crohn Disease

United Kingdom

Clinical Trials Sponsored by NIHR Clinical Research Facility, University Hospital Southampton NHS Foundation Trust

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cambodia

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