Clinical Trials Sponsored by NuCana plc

Total 11422 results

NuCana plc

Active, not recruiting

A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

Colorectal Neoplasms | Colorectal Cancer | Colorectal Cancer Metastatic | Colorectal Adenocarcinoma | Neoplasm, Colorectal

United States, Spain, United Kingdom, Italy, Germany, France
NuCana plc

Recruiting

A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma

Lymphoma | Solid Tumor | Advanced Cancer

United Kingdom
NuCana plc

Terminated

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Biliary Tract Cancer

Canada, United States, Spain, Hungary, Korea, Republic of, United Kingdom, Czechia, Germany, Russian Federation, Australia, France, Taiwan, Ukraine, Italy, Turkey
NuCana plc

Recruiting

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

Melanoma | Renal Cell Carcinoma | Gastric Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Advanced Cancer | Head and Neck Squamous Cell Carcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Classical Hodgkin Lymphoma | Neoplasm Malignant | Pleural... and other conditions

United Kingdom
NuCana plc

Completed

A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment

Colorectal Neoplasms | Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal

United States, France, United Kingdom
NuCana plc

Terminated

NUC-1031 in Patients With Platinum-Resistant Ovarian Cancer

Ovarian Cancer

United States, United Kingdom
Imperial College London
Nucana

Completed

NUC-1031 in Patients With Advanced Solid Tumours (ProGem1)

Cancer

United Kingdom
Neurana Pharmaceuticals, Inc.

Completed

A Phase 1 PK Study of Tolperisone in Healthy Subjects

Healthy

United States
Neurana Pharmaceuticals, Inc.

Completed

Effects of Tolperisone on Measures of Drowsiness and Cognitive Function

Healthy

United States
Humana Inc.
Boehringer Ingelheim; Humana Healthcare Research, Inc.

Active, not recruiting

Educational Intervention to Increase Select Guideline-recommended Cardioprotective Medications in Patients With Diabetes

Cardiovascular Diseases | Diabetes Mellitus, Type 2

United States
Lucyna Mastalerz

Recruiting

Long-term Aspirin Therapy as a Predictor of Decreased Susceptibility to SARS-CoV-2 Infection in Aspirin-Exacerbated Respiratory Disease (AERD-CoV19)

AERD - Aspirin Exacerbated Respiratory Disease

Poland
Faculdade de Motricidade Humana

Recruiting

Effects of Short- Term Intermittent Fasting Aerobic and Anaerobic Capacity (Performance)

Healthy Males | Men

Portugal
Faculdade de Motricidade Humana

Completed

The Effects of Leucine Metabolites in Performance, Body Composition and Biochemical Markers of Muscle Damage (LMET2IMPROVE)

Resistance Training

Portugal
Faculdade de Motricidade Humana

Completed

Breaking of Sitting Time Prevents Lower Leg Swelling (Break_sitting)

Edema Leg

Portugal
Evidation Health
Humana Co.Ltd.

Completed

Digital Self-Management Program for Medicare Advantage Members With Type 2 Diabetes- Impact on A1c

Diabetes Mellitus, Type 2

United States
Humana Co.Ltd.
Vitkovice Hospital

Completed

Effect of Galactooligosaccharides on Incidence of Atopic Manifestations in Infants

Atopic Dermatitis

Czech Republic
Zucara Therapeutics Inc.

Recruiting

A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes (ZONE)

Type 1 Diabetes Mellitus With Hypoglycemia

United States, Canada
Zucara Therapeutics Inc.

Terminated

Effect of ZT-01 on Glucagon During Hypoglycemia in Type 1 Diabetes Mellitus

Hypoglycemia | Type 1 Diabetes

Canada
Neurana Pharmaceuticals, Inc.

Completed

Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm (RESUME-1)

Back Pain | Acute Pain | Back Muscle Spasm | Back Strain | Back Spasm Upper | Muscle Spasm

United States
Neurana Pharmaceuticals, Inc.

Completed

Tolperisone in Acute Muscle Spasm of the Back (STAR)

Back Pain | Low Back Pain | Acute Pain | Muscle Cramp | Back Strain | Muscle Spasm | Back Spasm Upper Back

United States
USANA Health Sciences

Completed

Effect of a Multivitamin/Multimineral/Phytochemical Dietary Supplement on Indices of Human Health

Healthy

United States
Faculdade de Motricidade Humana

Completed

The Motor Neurological Soft Signs (MNSS) in Persons With Schizophrenia (MNSS)

Schizophrenia | Motor Skills Disorders | Psychomotor Status

Portugal
Mayo Clinic
Anumana, Inc.

Completed

A Multi-Center Study of Detection of Low Ventricular Ejection Fraction

Cardiac Disease

United States
Faculdade de Motricidade Humana

Completed

Lifestyle Intervention Program for Former Elite Athletes (Champ4Life)

Obesity

Portugal
Susana Morimoto

Completed

Endocrowns vs.Ceramic Onlays Used in Endodontically Treated Teeth- Randomized Clinical Study

Ceramic Restorations in Endodontically Treated Teeth

Brazil
Faculdade de Motricidade Humana

Completed

Psychomotor Therapy Effects in Adaptive Behavior and Motor Proficiency in Intellectual Disability

Intellectual Disability
Faculdade de Motricidade Humana

Completed

Effects of a Resistance and Stretching Training Program on Forward Head and Protracted Shoulder Posture Adolescents

Posture Disorders in Children

Portugal
Zuzana Zbožínková, M.Sc.

Unknown

Czech Multicentre Research Database of Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Airway Disease

Czechia
Anumana, Inc.
Mayo Clinic

Not yet recruiting

A Multicenter Pragmatic Implementation Study of ECG-AI-Based Clinical Decision Support Software to Identify Low LVEF (AIM ECG-AI)

Ventricular Ejection Fraction

United States
Faculdade de Motricidade Humana

Recruiting

Effects of Hydration Changes on Neuromuscular Function of Athletes (H2OAthletes)

Dehydration | Hyperhydration

Portugal
Faculdade de Motricidade Humana

Completed

The Effects of High Intensity Circuit Training in Nature Vs. Indoor on Exercise Performance, and Wellbeing

Green Exercise | Indoor Exercise

Portugal
Faculdade de Motricidade Humana

Completed

Effect of Sodium Bicarbonate on Exercise Performance

Sodium Bicarbonate

Portugal
Faculdade de Motricidade Humana

Completed

Effects of Facemask on Cardiorespiratory Performance

Facemask Impact on Cardiorespiratory Performance

Portugal
Evidation Health
Humana Co.Ltd.

Completed

Diabetes Coaching Program for Medicare Advantage Members With Type 2 Diabetes - Impact on A1c

Diabetes Mellitus, Type 2

United States
Faculdade de Motricidade Humana

Completed

Lifestyle Intervention in Overweight Women (PESO)

Obesity | Physical Activity | Weight Loss | Cardiovascular Risk Factor | Behavior, Health | Nutritional and Metabolic Disease | Lifestyle, Sedentary

Portugal
USANA Health Sciences

Recruiting

A Clinical Study to Determine if Beta Glucan Reduces the Incidence, Duration or Severity of URTIs Among Skiers

Upper Respiratory Tract Infections | Mental Stress

United States
Equipo Juana Crespo

Unknown

Ovarian Fragmentation Study (Crespo Medical Team)

IVF | Premature Ovarian Failure | Ovarian Failure

Spain
Angle plc
MidLantic Urology, LLC

Terminated

Characterization of Circulating Tumor Cells (CTCs) in High Risk and Early Metastatic Prostate Cancer Patients Using Parsortix® System (CHARTER)

Prostate Cancer | Castration-resistant Prostate Cancer | Biochemically Recurrent Prostate Carcinoma | High Risk Prostate Carcinoma

United States
Sujana Dontukurthy

Terminated

IPACK Versus Popliteal Sciatic Nerve Block in ACL Reconstruction

Anterior Cruciate Ligament Tear

United States
Waldkrankenhaus Protestant Hospital, Spandau
Humana Inc.

Completed

Nutritive Efficacy and Safety of a Modified Infant Formula With a Reduced Protein Content and Improved Protein Quality

Overweight

Germany
University of Miami
Humana Inc.

Completed

Improving Adherence to Post PCI Antiplatelet Therapy in Minority Populations

Coronary Artery Disease

United States
University of Miami
Humana Inc.

Completed

Improving Adherence to Statins Among Minority Populations

Dyslipidemia

United States
Zuzana Zbožínková, M.Sc.
Boehringer Ingelheim

Completed

Phenotypes of COPD in Central and Eastern Europe (POPE)

Chronic Obstructive Pulmonary Disease

Latvia, Croatia, Austria, Bulgaria, Czech Republic, Hungary, Poland, Russian Federation, Serbia, Slovakia, Slovenia
MedRegen LLC
Johns Hopkins University; ICON plc

Recruiting

MRG-001 as an Immunoregulatory and Regenerative Therapy for COVID-19 Patients

COVID-19 | ARDS, Human | Regeneration | Stem Cells

United States
Redx Pharma Plc
Merck Sharp & Dohme LLC

Completed

A Study to Assess RXC004 Efficacy in Advanced Solid Tumours After Progression on Standard of Care (SoC) Therapy (PORCUPINE2) (KEYNOTE-E86)

Advanced Solid Tumours

United Kingdom, Australia
4D pharma plc
Merck Sharp & Dohme LLC

Terminated

Live Biotherapeutic Product MRx0518 and Pembrolizumab Combination Study in Solid Tumors

Melanoma | Renal Cell Carcinoma | Solid Tumor | Non Small Cell Lung Cancer | Bladder Cancer | Oncology

United States
Neurana Pharmaceuticals, Inc.
Cognitive Research Corporation

Completed

Driving Simulation to Assess Non-Sedative Effects of Tolperisone

Driving Impaired

United States
Centro de Infertilidad y Reproducción Humana

Terminated

Use of IMSI in Poor Responders to IVF

Female Infertility

Spain
Centro de Infertilidad y Reproducción Humana

Completed

Low-dose GH Supplementation Increases Clinical Pregnancy Rate

Infertility

Spain
Centro de Infertilidad y Reproducción Humana

Withdrawn

Endometrial Scratching in In Vitro Fertilization Cycles With Oocyte Donation

Subfertility

Spain

Clinical Trials Sponsored by NuCana plc

Sponsors and Collaborators

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