The Motor Neurological Soft Signs (MNSS) in Persons With Schizophrenia (MNSS)

The aim is to contribute to the knowledge of the relationship between Motor Neurological Soft Signs (MNSS) and schizophrenia, as well as to point out the implications and recommendations for clinical and rehabilitative practices, in order to contribute to the identification of these signs as potential facilitators of prevention and a better follow-up in the psychosocial rehabilitation processes of the person with schizophrenia.

Study Overview

• Status: Completed
• Conditions: Schizophrenia; Motor Skills Disorders; Psychomotor Status
• Intervention / Treatment: Diagnostic test: Brief Motor Scale_portuguese version (BMS_pt)

Detailed Description

The aim is to contribute to the knowledge of the relationship between Motor Neurological Soft Signs (MNSS) and schizophrenia, as well as to point out the implications and recommendations for clinical and rehabilitative practices, in order to contribute to the identification of these signs as potential facilitators of prevention and a better follow-up in the psychosocial rehabilitation processes of the person with schizophrenia.

It is therefore important to answer the following starting questions:

• How can MNSS be assessed and analysed in the Portuguese population with schizophrenia?
• How does the manifestation of MNSS differ between people with and without schizophrenia?
• Do the MNSS of people with schizophrenia vary according to their functionality level including the following areas of activity (Cognition, Mobility, Self-Care, Interpersonal Relations, Daily Activities and Participation) and their motor experiences?
• How can the information obtained by applying a validated assessment tool for this purpose be made operational as a procedure for psychomotor assessment and intervention with this population?

The following objectives have been defined to answer these questions, which guide the work:

1. Translate, adapt and validate the BMS instrument (Jahn et al., 2006) for the Portuguese population with schizophrenia;
2. Explore the relationship of MNSS with demographic variables (e.g.: age, gender, education), clinical-therapeutic variables (e.g.: age of diagnosis, number of hospitalizations, medication, type of support) and psychosocial variables (e.g.: functionality, satisfaction and well-being, motor experiences);
3. Test a multifactorial model of the relationships between MNSS, demographic variables, functional clinical-therapeutic and psychosocial;
4. Compare MNSS in people with schizophrenia and people from a healthy control group.

• Study Type: Interventional
• Enrollment (Actual): 103
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Portugal
  • Lisbon, Portugal
    • Susana Guimarães

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Have a schizophrenia diagnoses

Exclusion Criteria:

• Have a motor disability
• Drugs consumer

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Supportive Care
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Other: Motor Neurological Soft Signs; motor test and an interview for the participants	Diagnostic test: Brief Motor Scale_portuguese version (BMS_pt); translate, adapt and validate Brief Motor Scale for portuguese population with schizophrenia

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Assessment of persons with schizophrenia with Brief Motor Scale - Portuguese version (BMS_pt) instrument	The aim of this study was to translate, adapt and validate a Portuguese version of the Brief Motor Scale (BMS_pt) in people with schizophrenia (Jahn et al, 2006). The participants (N=43) were evaluated twice with an interval of two weeks. In total, the sample collection lasted 6 weeks. Scale used and caracteristics: Unabbreviate title - Brief Motor Scale - Portuguese version Abbreviate title - BMS_pt Minimum value = 0; Maximum value = 2 Higher scores mean a worse outcome. Scale description: BMS_pt is a quantative test, which assessed motor neurological soft signs (MNSS) in two domains: motor coordination and motor sequencing. BMS_pt have a range score between 0 and 2 points for each item, domains and total score.	6 weeks

Collaborators and Investigators

• Sponsor: Faculdade de Motricidade Humana
• Investigators: Principal Investigator: Susana Guimarães, MD, Faculdade Motricidade Humana

Publications and helpful links

Helpful Links

• Validity and Reliability of the Portuguese Version of Brief Motor Scale in Persons with Schizophrenia: A Preliminary Study

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2017
• Primary Completion (Actual): December 1, 2019
• Study Completion (Actual): June 1, 2020

Study Registration Dates

• First Submitted: July 25, 2020
• First Submitted That Met QC Criteria: July 30, 2020
• First Posted (Actual): August 3, 2020

Study Record Updates

• Last Update Posted (Actual): June 2, 2023
• Last Update Submitted That Met QC Criteria: May 31, 2023
• Last Verified: July 1, 2020

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Mental Disorders; Schizophrenia Spectrum and Other Psychotic Disorders; Neurodevelopmental Disorders; Schizophrenia; Motor Skills Disorders
• Other Study ID Numbers: 32/2017

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No