Clinical Trials Sponsored by University Hospitals Leicester NHS Trust, UK

Total 2172 results

Loughborough University
University Hospitals of Derby and Burton NHS Foundation Trust; University Hospitals...

Completed

The Influence of High Impact Exercise on Musculoskeletal Health in Older Men (Hiphop)

Bone Strength | Neuromuscular Function

United Kingdom
University of Leicester
Leicester Royal Infirmary NHS Trust

Completed

A Clinical Trial Investigating Effect of Tinted Light on Perception of Tinnitus

Tinnitus

United Kingdom
University Hospitals, Leicester
Diabetes UK

Completed

Can Structured Education Promote Physical Activity in Those Identified With an Increased Risk of Developing Diabetes (PREPARE)

Prediabetic State

United Kingdom
Portsmouth Hospitals NHS Trust
Asthma UK

Completed

EXhaled Hydrogen Peroxide As a Marker of Lung diseasE (EXHALE) Pilot Study. (EXHALE Pilot)

Chronic Obstructive Pulmonary Disease | Asthma

United Kingdom
Nottingham University Hospitals NHS Trust
Diabetes UK

Completed

Evaluation of Education in the Secondary Prevention of Foot Ulceration in Diabetes (ESP)

Foot Ulceration in Diabetes

United Kingdom
Oxford University Hospitals NHS Trust
Cancer Research UK

Completed

Effect of Metformin on Breast Cancer Metabolism

Breast Cancer

United Kingdom
University of Nottingham
Nottingham University Hospitals NHS Trust; University Hospitals, Leicester

Completed

Small Particle Steroids in Refractory Asthma (SPIRA)

Asthma

United Kingdom
Womb Transplant UK
Oxford University Hospitals NHS Trust; Imperial College Healthcare NHS Trust

Recruiting

INvestigational Study Into Transplantation of the Uterus (INSITU)

Cervical Cancer | Postpartum Hemorrhage | Mayer-Rokitansky-Kuster Syndrome | Asherson's Syndrome

United Kingdom
University Hospital Southampton NHS Foundation...
Sheffield Teaching Hospitals NHS Foundation Trust; University Hospitals, Leicester and other collaborators

Completed

CPET and Outcome After Oesophagogastric Cancer Surgery

Upper Gastrointestinal Disorders

United Kingdom
Papworth Hospital NHS Foundation Trust
King's College London; University Hospitals, Leicester

Recruiting

Nasal Oxygen Therapy After Cardiac Surgery (NOTACS)

Coronary Artery Disease | Respiratory Failure | Cardiac Valve Disease

United Kingdom
University of Oxford
University Hospitals, Leicester; Oxford University Hospitals NHS Trust

Unknown

PERfusion CT in the FOXFIRE Trial to Study Blood Flow to Liver Metastases (PERFORM)

Metastatic Colorectal Cancer

United Kingdom
University Hospital Southampton NHS Foundation...
Cancer Research UK; The Christie NHS Foundation Trust; Celldex Therapeutics; Oxford... and other collaborators

Active, not recruiting

A Combination of Rituximab and Varlilumab Immunotherapy in Patients With B-cell Lymphoma (RiVa)

B Cell Lymphoma

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Diabetes UK

Completed

Study of CBME in the Relief of Painful Diabetic Neuropathy

Diabetic Neuropathy | Painful

United Kingdom
University Hospitals of North Midlands NHS Trust
Diabetes UK

Recruiting

Is Fat in the Liver a Marker of Post-Pregnancy Glycaemic Deterioration in Women With Gestational Diabetes? (FLiP-GD2)

Gestational Diabetes

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Arthritis Research UK

Unknown

Acquired Immunodeficiency in ANCA Associated Vasculitis (ACQUIVAS)

Systemic Vasculitis
Royal Free Hospital NHS Foundation Trust
Innovate UK

Active, not recruiting

CirrhoCare in COVID-19: A Pilot, Remote, Home Monitoring Study in Advanced Cirrhosis

Decompensated Cirrhosis

United Kingdom
Accunea Ltd.
Imperial College Healthcare NHS Trust; Hammersmith Hospitals NHS Trust; Innovate...

Withdrawn

Detecting Markers of Kidney Function With Intravenous Microdialysis

Kidney Diseases

United Kingdom
University of Leicester
Guy's and St Thomas' NHS Foundation Trust; Sheffield Teaching Hospitals NHS... and other collaborators

Not yet recruiting

Study on Optimal Temperature During Cardiopulmonary Bypass (THERMIC-4) (THERMIC-4)

Cardiovascular Diseases | Ischemic Heart Disease | Valvular Heart Disease | Surgery-Complications
University of Oxford
University of Leicester; Oxford University Hospitals NHS Trust

Active, not recruiting

RE-BLEED: A Digital Platform for Identifying Bleeding Patients - a Feasibility Study (RE-BLEED)

Hemorrhage | Trauma | Gastro Intestinal Bleeding

United Kingdom
University of Leicester
University of Nottingham; Nottingham University Hospitals NHS Trust

Completed

Evaluation of a Prototype Hand Held Hybrid Gamma Camera (BIVISTA)

Tumour

United Kingdom
University Hospital Birmingham NHS Foundation Trust
Pancreatic Cancer UK

Recruiting

The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study) (DETECTION)

Pancreatic Exocrine Insufficiency

United Kingdom
University of Leicester
University Hospitals, Leicester; Loughborough University; National Institute...

Completed

Upregulating the Nitric Oxide Pathway To Restore Autonomic Phenotype (UNTRAP). (UNTRAP)

Heart Failure | Arrhythmia

United Kingdom
Portsmouth Hospitals NHS Trust
University Hospitals, Leicester; Brighton and Sussex University Hospitals NHS... and other collaborators

Unknown

"Using Dilute Vinegar to Find Changes in Cells During Endoscopy for Patients With Barrett's Oesophagus" (The ABBA Study) (ABBA)

Barrett Esophagus

United Kingdom
University Hospitals of Derby and Burton NHS Foundation...
University Hospitals, Leicester

Recruiting

Memories in Heartbeats Study

Palliative Care

United Kingdom
King's College London
King's College Hospital NHS Trust; University College London Hospitals; Cambridge... and other collaborators

Recruiting

The Clinical Impact of the Basophil Activation Test to Diagnose Food Allergy

Egg Allergy | Food Allergy | Food Allergy in Children | Milk Allergy | Food Allergy in Infants | Nut Allergy | Food Allergen Sensitisation

United Kingdom
Norfolk and Norwich University Hospitals NHS Foundation...
Guy's and St Thomas' NHS Foundation Trust; University Hospitals, Leicester; University... and other collaborators

Recruiting

The CAVA Multicentre Dizziness Trial (CAVA 2)

Vestibular Migraine | Benign Paroxysmal Positional Vertigo (BPPV) | Ménière's Disease

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; Cancer Research UK

Recruiting

Platinum and Polyadenosine 5'Diphosphoribose Polymerisation Inhibitor for Neoadjuvant Treatment of Triple Negative Breast Cancer and/or Germline BRCA Positive Breast Cancer (PARTNER)

Breast Cancer

United Kingdom
The Leeds Teaching Hospitals NHS Trust
Cancer Research UK

Recruiting

Experiences and Perceptions of Colonoscopy and New Technologies

Bowel Cancer | Colonoscopy

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Cancer Research UK

Completed

A Feasibility Study for a Multicentre Randomised Controlled Trial to Compare Surgery With Needle Ablation Techniques in People With Small Renal Masses (4cm) (CONSERVE)

Renal Cancer

United Kingdom
The Leeds Teaching Hospitals NHS Trust
Cancer Research UK

Completed

Hepatitis C Rimantadine and Antiviral Combination Therapy (HepRiACT)

Hepatitis C

United Kingdom
Imperial College Healthcare NHS Trust
Barts & The London NHS Trust; Royal Free Hospital NHS Foundation Trust; University... and other collaborators

Active, not recruiting

TB PCR in BAL and EBUS-TBNA (TRiBE)

Tuberculosis

United Kingdom
University of Leicester
University of London; City, University of London; Leicestershire Partnership... and other collaborators

Recruiting

Adult Eating Disorder Assessment Study

Eating Disorders

United Kingdom
King's College Hospital NHS Trust
King's College London; University of Leicester

Completed

The Iron and Muscle Study

Iron-deficiency | CKD Stage 4 | CKD Stage 3

United Kingdom
University of Leicester
AstraZeneca; Royal Surrey County Hospital NHS Foundation Trust

Completed

The Effect of a SGLT2 Inhibitor on Glucose Flux, Lipolysis and Exercise in Type 2 Diabetes (SINGLED)

Type 2 Diabetes

United Kingdom
University Hospital Southampton NHS Foundation...
AstraZeneca; Cancer Research UK

Completed

Open Label Phase I/Randomised,Double Blind Phase II Study in mCRPC of AZD5363 In Combination With DP Chemotherapy (ProCAID)

Prostate Cancer

United Kingdom
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma (VAPOR)

Pancreatic Cancer | PDAC - Pancreatic Ductal Adenocarcinoma

United Kingdom
University of Birmingham
Royal Marsden NHS Foundation Trust; The Leeds Teaching Hospitals NHS Trust; Guy... and other collaborators

Active, not recruiting

Measuring the Quality of Surgical Care and Setting Benchmarks for Training Using Intuitive Data Recorder Technology (MASTERY)

Cancer | Surgery

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; Diabetes UK

Completed

Closing the Loop in Adults With Type 1 Diabetes (ANGELA01)

Type 1 Diabetes

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University College London Hospitals; Cambridge University Hospitals NHS Foundation... and other collaborators

Completed

Alternative Delivery of Dose Adjustment For Normal Eating (DAFNE) Trial in Patients With Type 1 Diabetes

Type 1 Diabetes Mellitus

United Kingdom
University of Kent
King's College Hospital NHS Trust; Royal Brompton & Harefield NHS Foundation... and other collaborators

Completed

Do Heat and Moisture Exchange Mask Reduce EIB and Cough Severity in Asthma

Asthma | Asthma, Exercise-Induced
Doccla UK
Northampton General Hospital NHS Trust; NHS Nene Clinical Commissioning Group

Completed

Nene Remote Monitoring Proof of Concept

Cardiovascular Diseases | Heart Failure | Stroke | Respiratory Disease

United Kingdom
Queen's University, Belfast
The Leeds Teaching Hospitals NHS Trust; Cambridge University Hospitals NHS... and other collaborators

Recruiting

Co-morbidity and Refractory Asthma - UK Severe Asthma Registry (UKSAR)

Asthma

United Kingdom
University of Leicester
Genentech, Inc.; Biomedical Research Centre- Respiratory (Glenfield Hospital...

Completed

Anti-ST2 (MSTT1041A) in COPD (COPD-ST2OP) (COPD-ST2OP)

COPD Exacerbation

United Kingdom
The Leeds Teaching Hospitals NHS Trust
Cambridge University Hospitals NHS Foundation Trust; Nottingham University... and other collaborators

Completed

Hospital Onset Diarrhoea Investigation (HOODINI)

Diarrhea

United Kingdom
Owlstone Ltd
University College, London; University of Athens; University Hospital, Ghent; University... and other collaborators

Completed

Lung Cancer Indicator Detection (LuCID)

Lung Cancer

Germany, United Kingdom, Belgium, Italy
Royal Marsden NHS Foundation Trust
University College, London; The Leeds Teaching Hospitals NHS Trust; Belfast Health... and other collaborators

Unknown

Targeted Radiotherapy in Androgen-suppressed Prostate Cancer Patients. (TRAP)

Prostate Cancer | Metastasis | Toxicity Due to Radiotherapy | Circulating Tumour DNA

United Kingdom
Owlstone Ltd
Cambridge University Hospitals NHS Foundation Trust; Cancer Research UK

Completed

PAN-study: Pan-Cancer Early Detection Study (PAN)

Gastric Cancer | Esophageal Cancer | Liver Cancer

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
The Urology Foundation, UK

Unknown

Hyaluronate for the Treatment and Prevention of Recurrent Urinary Tract Infection in Women Suffering Atrophic Vaginitis (HATPIN)

Urinary Tract Infections | Atrophic Vaginitis

United Kingdom
Newcastle University
Newcastle-upon-Tyne Hospitals NHS Trust; Arthritis Research UK

Completed

Autologous Tolerogenic Dendritic Cells for Rheumatoid Arthritis (AutoDECRA) (AutoDECRA)

Rheumatoid Arthritis

United Kingdom
Pennine Acute Hospitals NHS Trust
University Hospitals, Leicester; University of Manchester; University of Salford

Unknown

Refining and Testing the Diagnostic Accuracy of PAT-POPS

Pediatric ALL

United Kingdom

Clinical Trials Sponsored by University Hospitals Leicester NHS Trust, UK

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