Search clinical trials for: All patients presenting for high-risk cardiac surgery and who might post-operatively meet the study

Total 494173 results

Abiomed Inc.

Completed

RECOVER I Impella RECOVER LP/LD 5.0 Support System Safety and Feasibility Study (RECOVER I)

Cardiac Surgery

United States
Bristol-Myers Squibb
Pfizer; Duke Clinical Research Institute

Completed

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Acute Coronary Syndromes

Australia, Germany, Poland, United States, Spain, Brazil, France, Netherlands, Argentina, Mexico, Russian Federation, Colombia, Austria, Belgium, Czechia, Hungary, Israel, Peru, Switzerland, Korea, Republic of, Canada, Romania, Sweden, Ukrai... and more
PD Dr. Bertram Scheller
Goethe University; Dr. Franz Köhler Chemie GmbH (study medication and labeling)

Unknown

Evaluation if Physostigmine Reduces Symptoms in Patients Who Has Developed a Delirium in Intensive Care After a Surgery

Suspected Delirium After Elective or Emergency Heart Surgery | CAM-ICU Diagnosed Delirium

Germany
Yonsei University

Completed

Impact of High-dose Pretreatment of Rosuvastatin in Patients With Acute Coronary Syndrome Following Off-pump Coronary Artery Bypass: Results From the HIROP-ACS (HIgh-dose Pretreatment of Rosuvastatin During Off-Pump Coronary Bypass in Acute Coronary Syndrome) Study

A Total of 234 Patients With Acute Coronary Syndrome Who Will Undergo OPCAB.

Korea, Republic of
The First Affiliated Hospital of Henan University...

Not yet recruiting

Clinical Study on the Effect of Removal of Porphyromonas Gingivalis on Prognosis of Esophageal Cancer After Radical Surgery

Evaluate the DFS of Patients With Esophageal Cancer Who Underwent Radical Operation After Regular Removal of Porphyromonas Gingivalis
Nantes University Hospital

Recruiting

Prospective Multicenter Randomized and Controlled Study Evaluating the Benefit of Early Pulmonary Vein Isolation Compared to Usual Treatment in Patients Aged Over 75 Years and Presenting With Atrial Fibrillation (EDearly AF)

Atrial Fibrillation

France
Bayer
Janssen Research & Development, LLC

Not yet recruiting

An Observational Study to Learn More About How Safe Rivaroxaban is And How Well it Works in Children With Congenital Heart Disease Who Had a Heart Surgery Called the Fontan Procedure

Children | Congenital Heart Disease | Prevention of Venous Thromboembolism | Fontan Procedure

Japan
Abbott Medical Devices

Recruiting

Assert-IQ Implantable Cardiac Monitor (ICM) Post Market Study (Assert-IQ)

Atrial Fibrillation, Persistent | Cardiac Arrhythmia | Ablation | Atrial Fibrillation Paroxysmal

United States
Octapharma

Not yet recruiting

Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

Acquired Antithrombin Deficiency
University of Rochester
Varian Medical Systems

Recruiting

This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned. (DASBRT-RPC)

Recurrent Prostate Cancer After Surgery

United States
Gilead Sciences

Recruiting

Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy (ASCENT-07)

Stage IV Breast Cancer | Locally Advanced or Unresectable Metastatic Breast Cancer

Taiwan, Korea, Republic of, Australia, Greece, Spain, United States, United Kingdom, France, Israel, Malaysia, Japan, Belgium, Poland, China, Germany, Czechia, Singapore, Hungary, Brazil, Italy, South Africa, Portugal, Argentina, Hong... and more
Anthos Therapeutics, Inc.

Recruiting

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76) (LILAC-TIMI 76)

Atrial Fibrillation (AF)

United States, Canada, Israel, Japan, China, Brazil, Chile, United Kingdom, Bulgaria, Germany, Hungary, Italy, Poland, Romania, Spain, Czechia, Latvia, Mexico, India
Rijnstate Hospital
University Medical Center Groningen; Maastricht University Medical Center; Leiden... and other collaborators

Recruiting

Effects of Preoperative Multidisciplinary Team Meetings for High-risk, Adult, Noncardiac Surgical Patients (PREPARATION)

Postoperative Complications | Interdisciplinary Communication | Surgical Procedures, Operative | Preoperative Care | Cost-Benefit Analysis | Noncardiac Surgery | Comorbidities and Coexisting Conditions | Patient Care Team

Netherlands
Gilead Sciences
Alliance Foundation Trials, LLC.; NSABP Foundation Inc

Recruiting

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/NSABP B-63) (ASCENT-05)

Triple Negative Breast Cancer

United States
Murdoch Childrens Research Institute

Recruiting

Beat to Beat A Study in Paediatric, Adolescent and Young Adult Patients Who Are Undergoing or Have Undergone Cancer Therapy to Evaluate the Agreement Between QTc Measured Using 12 Lead Electrocardiogram (ECG) and a Wearable Device ECG

Neoplasms | Cardiac Arrhythmia

Australia
University Hospital, Basel, Switzerland

Recruiting

Impact of Personalised Cardiac Anaesthesia and Cerebral Autoregulation on Neurological Outcomes in Patients Undergoing Cardiac Surgery (PRECISION)

Postoperative Delirium | Postoperative Cognitive Dysfunction | Postoperative Stroke

Germany, Switzerland, United Kingdom
Novartis Pharmaceuticals

Recruiting

A Multi-center Study to Evaluate the Safety, Tolerability and Efficacy of TIN816 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery.

Acute Kidney Injury Following Cardiac Surgery

France, Taiwan, Belgium, Germany, Argentina, Spain, Czechia, Hungary, Singapore, Estonia, Brazil, Lithuania
Pfizer
Thrombolysis In Myocardial Infarction (TIMI)

Recruiting

A Study of Ponsegromab in People With Heart Failure (GARDEN TIMI 74)

Heart Failure

United States, Canada, China, Australia, Spain, Japan, Czechia, Hungary, Germany, United Kingdom, Poland
M.D. Anderson Cancer Center
National Institutes of Health (NIH)

Recruiting

A Phase II Randomized Controlled Trial to Determine the Efficacy of an auGmented reAlity gaMe in pediatrIc caNcer Patients Who Are Opioid Naïve Undergoing Surgery to Reduce Postoperative Opioid Use (GAMING-ON Study)

Cancer | Pediatric ALL

United States
Korea University Anam Hospital

Recruiting

A Study to Evaluate the Impact of Pre-procedural Intracoronary Nicorandil Injection to PREVENT reductioN Of decREased TIMI FLOW in Patients Who Undergoing Percutaneous Coronary Intervention for the Coronary Artery Disease

Coronary Artery Disease | Percutaneous Coronary Intervention | No-Reflow Phenomenon

Korea, Republic of
University of Florida
National Institute of Nursing Research (NINR); Ohio State University

Recruiting

Dysphagia in Cardiac Surgical Patients

Cardiovascular Diseases | Dysphagia

United States
Asklepion Pharmaceuticals, LLC

Recruiting

A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart Defects

Atrioventricular Septal Defect | Ventricular Septal Defect | Primum Atrial Septal Defect

United States
Second Affiliated Hospital of Wenzhou Medical University
The First People's Hospital of Wenling

Recruiting

A Study of Huperzine A Injection in Reducing Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery

Injection | Delirium in Old Age | Post Operative Delirium | Non-cardiac Surgery

China
Acceleron Pharma, Inc., a wholly-owned subsidiary...

Recruiting

Study of Sotatercept in Newly Diagnosed Intermediate- and High-Risk PAH Participants (MK-7962-005/A011-13) (HYPERION)

Pulmonary Arterial Hypertension

United States, Belgium, France, Germany, Spain, Argentina, Australia, Austria, Colombia, Croatia, Denmark, Greece, Israel, Korea, Republic of, Netherlands, Portugal, Serbia, Taiwan, Brazil, Canada, Czechia, Italy, New Zealand, Sweden, S... and more
Acceleron Pharma, Inc., a wholly-owned subsidiary...

Recruiting

A Long-term Follow-up Study of Sotatercept for PAH Treatment (MK-7962-004/A011-12) (SOTERIA)

Pulmonary Arterial Hypertension | PAH

United States, France, Germany, Spain, Sweden, Argentina, Australia, Austria, Colombia, Croatia, Denmark, Greece, Israel, Italy, Korea, Republic of, Netherlands, New Zealand, Portugal, Serbia, Taiwan, United Kingdom, Brazil, Canada, B... and more
Huazhong University of Science and Technology
Qilu Hospital of Shandong University; Hunan Cancer Hospital; The Third Xiangya... and other collaborators

Recruiting

Clinical Efficacy of Adjuvant Chemotherapy in Patients With Locally Advanced Cervical Cancer Who Did Not Meet the NCCN Guidelines for Adjuvant Treatment After NACT Combined With Surgery

Cervical Cancer | Uterine Cervical Neoplasms

China
Ancora Heart, Inc.

Recruiting

Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study

Dilated Cardiomyopathy | Heart Failure With Reduced Ejection Fraction (HFrEF)

United States, France, Netherlands, Czechia, Belarus, Belgium, Serbia
SFJ Pharmaceuticals, Inc.

Recruiting

Bentracimab in Ticagrelor-treated Patients With Uncontrolled Bleeding or Requiring Urgent Surgery or Invasive Procedure (REVERSE-IT)

Hemorrhage | Invasive Procedure | Urgent Surgery

United States, Netherlands, China, Sweden, Austria, Belgium, France, Italy, Spain, Switzerland, United Kingdom, Canada, Germany
Actelion

Recruiting

Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension (UNISUS)

Pulmonary Arterial Hypertension

Belgium, United States, Italy, Canada, Taiwan, Greece, China, Korea, Republic of, Germany, Israel, Austria, Russian Federation, Australia, Thailand, United Kingdom, Brazil, Malaysia, Spain, Ukraine, Bulgaria, Colombia, Mexico, Turkey, Vietna... and more
National Cancer Institute (NCI)

Recruiting

BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Acute Myeloid Leukemia Post Cytotoxic Therapy

United States
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Recruiting

A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease (CULTIVATE)

Crohn's Disease

United States, Korea, Republic of, Netherlands, Colombia, Israel, Italy, Lebanon, Mexico, Poland, Spain, Turkey, Australia, Georgia, Czechia, Belgium, Germany, South Africa, Greece, Russian Federation, United Kingdom, Croatia, Serbia and more
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Recruiting

An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis (ELEVATE UC OLE)

Ulcerative Colitis

Poland, Japan, Georgia, Estonia, United States, Czechia, Australia, Korea, Republic of, Lithuania, Italy, Hungary, Turkey, Spain, Romania, Serbia, Germany, France, Bulgaria, Austria, Belarus, Canada, Croatia, Denmark, Israel, Latvia, Lebanon and more
Memorial Sloan Kettering Cancer Center

Recruiting

A Study to Test the Safety of Immunotherapy With Nivolumab Alone or With Ipilimumab Before Surgery for Bladder Cancer Patients Who Are Not Suitable for Chemotherapy

Bladder Cancer

United States
Children's Oncology Group
National Cancer Institute (NCI); EsPhALL Network/ BFM Study Group

Recruiting

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia | T Acute Lymphoblastic Leukemia | Mixed Phenotype Acute Leukemia

United States, Canada, Puerto Rico, Australia, Finland, New Zealand, Saudi Arabia, Germany, Austria, Belgium, Chile, Czechia, France, Italy, Netherlands, Sweden, Switzerland, Hong Kong, Israel
Chinese University of Hong Kong

Recruiting

Fibroscan Study in HCC

Confirmed Diagnosis of Hepatocellular Carcinoma | Patients Who Are Scheduled to Undergo Transarterial Chemobolization, Systemic Therapy Surgery | Child's A to C Cirrhosis

Hong Kong
Frantz Viral Therapeutics, LLC
University of California, San Francisco; Laser Surgery Care; Amarex CRO; Anal Dysplasia...

Active, not recruiting

Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL (anal HSIL HIV-)

HPV Infection | Anal Dysplasia | Anal High Grade Squamous Intraepithelial Lesion | Anal Precancerous Condition | AIN 2/3 | HPV Disease

United States
National Cancer Institute (NCI)

Active, not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Glioma | Hematopoietic and Lymphoid Cell Neoplasm | Melanoma | Lymphoma | Multiple Myeloma | Recurrent Ovarian Carcinoma | Breast Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Skin Carcinoma | Gastric Carcinoma | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory... and other conditions

United States, Puerto Rico, Guam
Amgen

Active, not recruiting

Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke (VESALIUS-CV)

Coronary Heart Disease (CHD)

Canada, France, United States, Spain, United Kingdom, Korea, Republic of, Netherlands, Austria, Australia, Czechia, Taiwan, Finland, Hungary, Italy, Poland, Greece, Germany, Brazil, Latvia, Denmark, Mexico, Russian Federation, Bulgaria and more
Universitätsmedizin Mannheim
Heidelberg University

Completed

Cilengitide and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Lung Cancer (CIRAB)

Lung Cancer | Brain and Central Nervous System Tumors

Germany
University of Edinburgh
NHS Lothian

Completed

A Study to Identify the Incidence of Post Traumatic Stress Symptoms in Patients With Delirium Following Cardiac Surgery

Delirium | Stress Disorders, Post-Traumatic | Cardiac Disease
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Completed

A Study to Assess the Safety and Efficacy of Oral Etrasimod in Adult Participants With Eosinophilic Esophagitis (VOYAGE)

Eosinophilic Esophagitis

United States, Spain, Switzerland, Australia, Belgium, Netherlands, Canada, Germany
Children's Hospital Medical Center, Cincinnati
Uganda Heart Institute; Murdoch Children's Research Institute, Melbourne Australia

Active, not recruiting

A Long-term Follow up Study for Patients Who Participated in the GOAL Trial (GOAL-Post)

Rheumatic Heart Disease

Uganda
Hoffmann-La Roche
NSABP Foundation Inc; German Breast Group

Active, not recruiting

A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE)

Breast Cancer

United States, Italy, United Kingdom, Canada, Czechia, Argentina, Austria, Belgium, Brazil, China, France, Germany, Guatemala, Ireland, Panama, Spain, Sweden, Taiwan, Turkey, Colombia, Hong Kong, Peru, Switzerland, South Africa, Israel, G... and more
Pfizer
Astellas Pharma Inc; Medivation LLC, a wholly owned subsidiary of Pfizer Inc.

Active, not recruiting

Safety and Efficacy Study of Enzalutamide in Patients With Nonmetastatic Castration-Resistant Prostate Cancer (PROSPER)

Prostate Cancer | Cancer of the Prostate | Nonmetastatic Castration-Resistant Prostate Cancer

Hong Kong, Canada, China, Germany, Spain, Netherlands, United Kingdom, Korea, Republic of, Taiwan, Australia, Denmark, France, United States, Singapore, Poland, Malaysia, Turkey, Belgium, Argentina, Thailand, Slovakia, Brazil, Finland, Ita... and more
Concert Pharmaceuticals

Completed

A Study to Evaluate the Durability of Response Study of CTP-543 in Adult Patients With Moderate to Severe Alopecia Areata

Alopecia Areata

United States
Novo Nordisk A/S

Completed

Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity (SELECT)

Obesity | Overweight

United States, France, Spain, Taiwan, United Kingdom, Germany, India, Brazil, Canada, Japan, Malaysia, Russian Federation, Australia, Norway, Mexico, Netherlands, Portugal, Hungary, Italy, Austria, Greece, South Africa, Turkey, Finland, Puerto Rico and more
National Cancer Institute (NCI)

Active, not recruiting

Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases

Metastatic Malignant Neoplasm in the Brain

United States
Pfizer
Astellas Pharma Inc; Medivation LLC, a wholly owned subsidiary of Pfizer Inc.

Active, not recruiting

Safety and Efficacy Study of Enzalutamide Plus Leuprolide in Patients With Nonmetastatic Prostate Cancer (EMBARK)

Prostate Cancer | Cancer of the Prostate | Hormone Sensitive Prostate Cancer

Canada, United States, France, Spain, Australia, Sweden, Taiwan, Finland, Korea, Republic of, Netherlands, United Kingdom, Denmark, Brazil, Slovakia, Austria, Italy, Poland
University Health Network, Toronto

Completed

Prostatectomy Adaptive Radiation Therapy (ART)

Prostate Cancer

Canada
Cerus Corporation

Active, not recruiting

Study to Evaluate the Efficacy & Safety of the INTERCEPT Blood System for RBCs in Complex Cardiac Surgery Patients (ReCePI)

Anemia

United States

Search clinical trials for: All patients presenting for high-risk cardiac surgery and who might post-operatively meet the study

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