Search clinical trials for: BF2.649 versus placebo

Total 72803 results

Bioprojet

Completed

BF2.649 in Patients With OSA, Still Complaining of EDS and Refusing to be Treated by CPAP. (HAROSA2)

Obstructive Sleep Apnea | Excessive Daytime Sleepiness

France
Bioprojet

Active, not recruiting

Efficacy and Safety of Pitolisant in Pediatric Narcoleptic Patients With or Without Cataplexy, Double-blind Study Followed by a Prolonged Open-label Period

Narcolepsy Without Cataplexy | Narcolepsy With Cataplexy

France, Italy, Russian Federation, Finland, Netherlands
Bioprojet

Completed

Effects of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy.

Treatment of Excessive Daytime Sleepiness in Narcolepsy

France
Bioprojet

Completed

Pharmacokinetics of BF2.649 in Renal Impairment

Renal Impairment

France
Bioprojet

Not yet recruiting

Proof of Concept Study on Pitolisant Effect on Autism Spectrum Disorders in Children and Adolescents

Autism Spectrum Disorder
University of Texas Southwestern Medical Center
Stanley Medical Research Institute; Bioprojet

Completed

Study to Demonstrate Cognitive Enhancing Effects of BF2.649

Schizophrenia

United States
Bioprojet

Completed

Pitolisant to Assess Weekly Frequency of Cataplexy Attacks and EDS in Narcoleptic Patients (HARMONY CTP)

Excessive Daytime Sleepiness | Narcolepsy With Cataplexy

Hungary
Bioprojet

Completed

Efficacy and Safety of BF2.649 in Excessive Daytime Sleepiness (EDS) in Parkinson's Disease (HARPS1)

Parkinson's Disease

France
Bioprojet

Completed

Dose-range Finding Study of BF2.649 Effect on Patients With Obstructive Sleep Apnea (OSA)

Excessive Daytime Sleepiness | Obstructive Sleep Apnoea

France
Bioprojet

Completed

Efficacy and Safety of BF2.649 in Excessive Daytime Sleepiness (EDS) in Parkinson's Disease (HARPS2)

Parkinson's Disease

Germany
Bioprojet

Completed

BF2.649 in Patients With OSA and Treated by CPAP But Still Complaining of EDS (HAROSA1)

Obstructive Sleep Apnea | Excessive Daytime Sleepiness

France
Bioprojet

Completed

Determination the Abuse Potential of Pitolisant in Healthy, Non-Dependent Recreational Stimulant Users

Healthy | Drug Abuse

Canada
St. Luke's-Roosevelt Hospital Center
GlaxoSmithKline

Withdrawn

Trial of Treatment of Atopic Dermatitis With Concurrent Altabax® and Topical Low-Potency Corticosteroids Versus Low-Potency Corticosteroid Mono-therapy

Atopic Dermatitis

United States
Bioprojet

Completed

Efficacy and Safety Study of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy (Harmony1)

Sleep Disorders | Narcolepsy | Cataplexy | Excessive Daytime Sleepiness

Switzerland
GlaxoSmithKline

Completed

Carcinogenicity Study of Bupropion

Depressive Disorder | Cancer
Bioprojet

Completed

Pitolisant (BF2.649) in the Treatment of EDS in Patients With OSA (HAROSA3)

Obstructive Sleep Apnea | Excessive Daytime Sleepiness

Bulgaria, North Macedonia
Bioprojet

Completed

Long Term Open Label Study in Narcolepsy With BF2.649 (Pitolisant) (HARMONYIII)

Narcolepsy | Cataplexy

France
Bioprojet

Completed

Patient Narcoleptic Treated With BF2.649 (Pitolisant) in add-on to Sodium Oxybate (HARMONY IV) (HARMONY IV)

Narcolepsy

France
Bioprojet

Completed

Efficacy and Safety Study of BF2.649 and BF2.649 Add on Modafinil on Cataplexy in Patients With Narcolespy (Harmony2)

Narcolepsy | Cataplexy | Excessive Daytime Sleepiness

Switzerland
Bioprojet

Withdrawn

Pitolisant (BF2.649) in the Treatment of Excessive Daytime Sleepiness in Patients With Obstructive Sleep Apnoea Syndrome, Treated or Not by Nasal Continuous Positive Airway Pressure, But Still Complaining of Excessive Daytime Sleepiness (HAROSA IV)

Obstructive Sleep Apnea | Excessive Daytime Sleepiness

France
Bioprojet

Withdrawn

A Trial Evaluating Pitolisant (BF2.649) in Alcohol Use Disorder Treatment (PoC Alcohol)

Alcohol Abuse, Nervous System
Bioprojet

Completed

Dose Range Finding Study of BF2.649 Versus Placebo to Treat Excessive Daytime Sleepiness in Parkinson's Disease Patients

Parkinson's Disease | Excessive Daytime Sleepiness

France
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

External Mastalgia-oil Versus Oral Tamoxifen in Premenopausal Women With Severe Mastalgia

Mastalgia

China
Riadh Boukef

Recruiting

Enantyum® IV Versus Piroxen® IM in Emergency Pain Management (PiDex)

Traumatic Injury

Tunisia
Aurora Health Care

Not yet recruiting

Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR (ATRIUM)

Atrial Fibrillation | Tachycardia Atrial | Atrial Flutter With Rapid Ventricular Response

United States
Akeso

Not yet recruiting

A Study of AK104+Lenvatinib in Combination With Transarterial Chemoembolization (TACE) Versus TACE in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Efficacy and Safety of Angiotensin II Injection Versus Placebo in Patients With Refractory Distributed Shock

Vasodilatory Shock

China
University of Monastir

Not yet recruiting

Paracetamol-Tramadol and Paracetamol-caffeine Versus Placebo in the Emergency Discharge Treatment of Renal Colic (RC)

Renal Colic
Gilead Sciences

Recruiting

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With Biktarvy (ARTISTRY-2)

HIV-1-infection

United States, Puerto Rico
Christoph Berger

Not yet recruiting

A Trial of Placebo Versus Macrolide for Mycoplasma Pneumoniae Childhood Pneumonia: MYTHIC Study (MYTHIC)

Community Acquired Pneumonia in Children | Mycoplasma Pneumoniae | Mycoplasma Pneumoniae Pneumonia

Switzerland
Cairo University

Not yet recruiting

Intrathecal Non-preservative-free Morphine With Bupivacaine Versus Intrathecal Bupivacaine Alone for Analgesia in Unilateral Inguinal Hernia Repair Surgeries

Pain, Postoperative

Egypt
Universitaire Ziekenhuizen KU Leuven

Recruiting

Nodular Shrinking in Dupuytren Disease (Echo)

Dupuytren's Disease

Belgium
Arab Contractors Medical Centre

Not yet recruiting

Colchicine Versus Beta-blockers, Angiotensin-converting Enzyme Inhibitors, and Statins for Prevention of Chemotherapy-Induced Cardiomyopathy (BASiC-CIC)

Chemotherapy Induced Systolic Dysfunction

Egypt
James Tarbox, MD
Texas Tech University Health Sciences Center

Recruiting

Penicillin Allergy Delabeling After a One-Dose Versus Two-Dose Graded Direct Oral Challenge

Penicillin Allergy

United States
Murdoch Childrens Research Institute

Recruiting

Analysing HIgh Dose Probiotic Peanut Oral Immunotherapy (PPOIT) and High Dose Peanut Oral Immunotherapy (OIT) Versus LOw Dose Peanut OIT for Peanut Allergy (HILO)

Peanut Allergy

Australia
Mahmoud Yousry Rashwan Hefny

Recruiting

Posterior Innominate Mobilization Versus Muscle Energy Technique on Lumbopelvic Angles in Sacroiliac Joint Dysfunction (MET)

Sacroiliac Joint Dysfunction

Egypt
Johns Hopkins University

Not yet recruiting

Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome

Staphylococcus Aureus | Microbial Colonization | Neonatal Infection

United States
St. Olavs Hospital
Helsinki University Central Hospital; University Hospital of North Norway; Helse... and other collaborators

Not yet recruiting

The Effect of Local Application of Tranexamic Acid Versus Placebo on Postoperative Complications in Plastic Surgery.

Surgical Complication
RDC Clinical Pty Ltd

Recruiting

Comparison of 2 Extracts of Saw Palmetto Versus Placebo on BPH Symptoms

Benign Prostatic Hyperplasia

Australia
Nexira

Recruiting

Study to Evaluate the Physiological Effects on the Skin of 3 Food Supplements Versus Placebo in 40-60 Years Old Female Subjects

Healthy Volunteers

France
Tanta University

Recruiting

Preoperative Oral Carbohydrate Loading Versus Fasting in Patients Undergoing Major Abdominal Surgery

Fasting | Major Abdominal Surgery | Carbohydrate

Egypt
medac GmbH

Not yet recruiting

Efficacy and Safety of Methotrexate Versus Placebo in Adults With Atopic Dermatitis.

Moderate to Severe Atopic Dermatitis
60 Degrees Pharmaceuticals LLC

Not yet recruiting

Oral Tafenoquine Plus Standard of Care Versus Placebo Plus Standard of Care for Babesiosis

Babesiosis
International Research Training Group 2804
German Research Foundation; Uppsala University; University Hospital Tuebingen

Recruiting

Estradiol and Stress Reactivity in Women

Stress vs. Control | Estradiol vs. Placebo

Germany
Università Vita-Salute San Raffaele

Recruiting

Antibiotic-Loaded Cement Versus Non-Antibiotic-Loaded Cement in Hip Prosthesis Surgery for Proximal Femur Fractures

Proximal Femoral Fractures

Italy
Ain Shams University

Recruiting

Potential Role of Intravenous Lidocaine Versus Intravenous Ketamine for Pain Management in Fibromyalgia Patients

Anesthesia

Egypt
Alexion Pharmaceuticals, Inc.

Recruiting

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM (DepleTTR-CM)

Transthyretin Amyloid Cardiomyopathy

United States, Spain, United Kingdom, Norway, Israel, Korea, Republic of, Belgium, France, Germany, Italy, Japan, China, Australia, Argentina, Austria, Taiwan, Switzerland, Canada, Sweden, Poland, Denmark, Turkey, Brazil, Netherlands, G... and more
Concept Medical Inc.

Not yet recruiting

Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease (MAGICAL BTK)

Arterial Disease of Legs
FutureGen Biopharmaceutical (Beijing) Co., Ltd

Recruiting

M108 Plus CAPOX Versus Placebo Plus CAPOX as First-line Treatment for Claudin (CLDN) 18.2-Positive, HER2-Negative, PD-L1 CPS<5, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma.

Locally Advanced Unresectable or Metastatic Gastric Cancer | Locally Advanced Unresectable or Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma

China
Clinical Hospital Centre Zagreb

Recruiting

Prophylactic Tranexamic Acid Versus Adrenaline During Flexible Bronchoscopy (TAVA2)

Bleeding | Hemoptysis

Croatia

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