Search clinical trials for: CK-3828136, CK-136

Total 455 results

Cytokinetics

Recruiting

A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult Participants

Healthy Participants

United States
Cytokinetics

Recruiting

A Single and Multiple Ascending Dose Study of CK-4021586 in Healthy Adult Participants

Healthy Participants

United States
Cytokinetics

Completed

A Study of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

United States
Hanlim Pharm. Co., Ltd.

Recruiting

Observational Study on the Improvement of Dry Eye Syndrome, Treatment Satisfaction, and Intraocular Tolerance With Diquasol Eye Drops

Dry Eye Syndrome

Korea, Republic of
Cytokinetics

Completed

Study to Evaluate the Effect of Aficamten Administration on QT/QTc Interval

Healthy Participants

United States
Cytokinetics

Completed

PK and Tolerability of IV and Oral CK-1827452 in Patients With Ischemic Cardiomyopathy and Angina

Myocardial Ischemia | Heart Failure | Angina Pectoris

Georgia, Russian Federation
University of Aarhus
TRYG Foundation

Unknown

Cognitive Behavioral Therapy for Adolescents With Social Anxiety Disorder

Social Anxiety Disorder

Denmark
Cytokinetics

Completed

A Study of CK-2017357 in Patients With Peripheral Artery Disease and Symptomatic Claudication

Intermittent Claudication | Peripheral Artery Disease

United States
Cytokinetics
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Pharmacodynamic Study of CK-2017357 in Patients With Generalized Myasthenia Gravis

Myasthenia Gravis

United States
Oregon Social Learning Center
Office of Planning, Research & Evaluation

Recruiting

KEEP Connecting Kin (KEEP-CK)

Parenting | Externalizing Behavior | Parent Stress | Internalizing Behavior | Child Permanency | Service Utilization

United States
CK Regeon Inc.

Completed

Safety, Tolerability, and Pharmacokinetic Evaluations of CKR-051 After Transdermal Administration in Healthy Male Subjects

Healthy

Korea, Republic of
Cytokinetics

Completed

A Single and Multiple Ascending Dose Study of CK-3773274 in Healthy Adult Subjects

Healthy Subjects | Symptomatic Obstructive Hypertrophic Cardiomyopathy

United States
Cytokinetics

Completed

Dose-finding Study to Evaluate the Safety, Tolerability, PK, and PD of CK-3773274 in Adults With HCM (REDWOOD-HCM)

Hypertrophic Cardiomyopathy (HCM)

United States, Spain, Italy, Netherlands
Cytokinetics

Completed

A Study for Patients Who Completed VITALITY-ALS (CY 4031) (VIGOR-ALS)

Amyotrophic Lateral Sclerosis (ALS)

United States, Netherlands, Canada, Belgium, United Kingdom, France, Germany, Ireland, Italy, Portugal, Spain
Cytokinetics

Terminated

Phase II Study of the Effect of CK-1827452 Injection on Myocardial Efficiency

Heart Failure

Canada, United States
Cytokinetics
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.

Completed

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM (SEQUOIA-HCM) (SEQUOIA-HCM)

Obstructive Hypertrophic Cardiomyopathy (oHCM)

United States, France, Spain, Portugal, Germany, China, United Kingdom, Israel, Netherlands, Denmark, Czechia, Hungary, Italy, Poland
Checkpoint Therapeutics, Inc.
Novotech (Australia) Pty Limited

Recruiting

Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers

Melanoma | Renal Cell Carcinoma | Head and Neck Cancer | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Non Hodgkin Lymphoma | Endometrial Cancer | Carcinoma, Small Cell | Urothelial Carcinoma | Classical Hodgkin Lymphoma | Merkel Cell Carcinoma | Cutaneous Squamous Cell Carcinoma | Malignant Mesothelioma, Advanced

Australia, New Zealand, Thailand, Ukraine, Spain, Russian Federation, France, Poland, South Africa
Cytokinetics

Completed

A Study of CK-1827452 Infusion in Stable Heart Failure

Heart Failure

United States, United Kingdom, Georgia, Russian Federation
Astellas Pharma Global Development, Inc.
Cytokinetics

Completed

A Study to Assess the Effect of CK-2127107 on Physical Function in Subjects With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)

United States
Astellas Pharma Global Development, Inc.
Cytokinetics

Terminated

A Study to Assess the Anti-fatigability Effect of CK-2127107 in Elderly Male and Female Subjects With Limitations in Mobility

Mobility Limitation

United States
Cytokinetics
Astellas Pharma Inc

Completed

A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS) (FORTITUDE-ALS)

Amyotrophic Lateral Sclerosis

United States, Netherlands, Australia, Canada, Ireland, Spain
The Cooper Health System

Withdrawn

Stereotactic Radiosurgery for Soft Tissue Sarcoma

Soft Tissue Sarcoma

United States
Centre Antoine Lacassagne

Completed

Hypofractionated Radiation by CyberKnife as a Mean of the Tumor Site's Radiation After Conventional Breast Radiation. (CYBERBOOST)

Breast Cancer

France
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.

Recruiting

An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM

Obstructive Hypertrophic Cardiomyopathy

China
Cytoki Pharma
SGS Life Sciences, a division of SGS Belgium NV

Completed

A Phase 1 Study to Investigate Safety, Tolerability, and Pharmacokinetics of CK-0045 in Healthy Participants and Otherwise Healthy Participants With Obesity

Healthy

Belgium
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
Cytokinetics

Completed

Safety, Tolerability and Pharmacokinetics Study of CK-3773274

Healthy Adult Subjects | Obstructive Hypertrophic Cardiomyopathy

China
Cytokinetics

Completed

Pharmacokinetics of Oral CK-1827452 in Patients With Stable Heart Failure

Heart Failure

Georgia
Instituto Dante Pazzanese de Cardiologia

Terminated

Sevoflurane and Percutaneous Coronary Intervention by Stent

Myocardial Infarction

Brazil
Seoul National University Hospital

Terminated

Neoadjuvant Chemotherapy Response in Metaplastic Carcinoma of Triple Negative Breast Cancer (NEO-SMART)

Metaplastic Breast Carcinoma

Korea, Republic of
Cytokinetics

Completed

Study to Evaluate the Safety and Efficacy of IV Infusion Treatment With Omecamtiv Mecarbil in Subjects With Left Ventricular Systolic Dysfunction Hospitalized for Acute Heart Failure (ATOMIC-AHF)

Heart Failure

United States, Canada, Germany, Italy, Netherlands, Belgium, France, Czechia, Australia, Russian Federation, Hungary, Poland, Bulgaria, Slovakia, United Kingdom, Finland, Greece, Lithuania, Norway
Cytokinetics
Astellas Pharma Global Development, Inc.

Completed

A Study of CK-2127107 in Patients With Spinal Muscular Atrophy

Spinal Muscular Atrophy

United States, Canada
Cytokinetics

Completed

Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure (METEORIC-HF)

Heart Failure With Reduced Ejection Fraction

United States, Hungary, France, Canada, Netherlands, Germany, Poland, Italy, Sweden
Cytokinetics

Enrolling by invitation

Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM (FOREST-HCM)

Symptomatic Hypertrophic Cardiomyopathy (HCM)

United States, France, Israel, Spain, United Kingdom, Italy, Poland, Hungary, Denmark, Netherlands, Germany, Czechia, Portugal
Cytokinetics

Completed

Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year (VITALITY-ALS)

Amyotrophic Lateral Sclerosis

Canada, United States, Netherlands, France, United Kingdom, Belgium, Germany, Spain, Ireland, Italy, Portugal
Biosite

Withdrawn

Rapid Assessment of Cardiac Markers for the Evaluation of Acute Coronary Syndrome (RACE-ACS)

Acute Coronary Syndrome

United States
University of Delaware

Recruiting

Sensorimotor Control During Postural Transitions in CP

Cerebral Palsy

United States
Centre Francois Baclesse, Luxembourg

Active, not recruiting

IMRT Followed by CyberKnife Boost Focused on the Gross Residual Pelvic Tumor Volume (Boost_Pelvis)

Pelvis Tumors

Luxembourg
Wang Hongxia
Tianjin Eye Hospital

Unknown

Comparison of Anterior Corneal Optical Aberration Induced by CK and Hyperopic LASIK

Refractive Error

China
Ullevaal University Hospital

Completed

Comparison of Blood Cardioplegia and Custodiol

Myocardial Protection | Mitral Insufficiencies

Norway
Checkpoint Therapeutics, Inc.

Completed

Phase I/II Study of CK-101 in NSCLC Patients and Other Advanced Solid Tumors

Lung Diseases | Adenocarcinoma | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

United States, Thailand, New Zealand, Australia, Poland
FH ORTHO
Slb Pharma

Recruiting

Performance and Safety Evaluation of the FHK®-CK Knee Prosthesis (FHK-CK)

Total Knee Arthroplasty

France
Georgetown University

Terminated

CyberKnife Stereotactic Accelerated Partial Breast Irradiation (SAPBI) (CK-SAPBI)

Breast Cancer | DCIS | Invasive Ductal Carcinoma

United States
University College, London

Unknown

Metabolic Response to Playing Video Games: Two Arm Trial

Sedentary Lifestyle | Appetite and General Nutritional Disorders

United Kingdom
Centre Antoine Lacassagne

Completed

Stereotactic Radiosurgery in Treating Patients Undergoing Chemotherapy and Radiation Therapy For Stage III Non-Small Cell Lung Cancer

Lung Cancer

France
VA Office of Research and Development

Completed

Evaluating Two Types of Cognitive Training in Veterans With Schizophrenia

Schizophrenia

United States
The Cooper Health System

Unknown

A Study of Pre-Operative Cyberknife in Patients With Potentially Resectable Pancreas Cancer

Pancreatic Cancer | Pancreatic Adenocarcinoma | Pancreas Adenocarcinoma | Pancreas Cancer | Adenocarcinoma of the Pancreas

United States
University Hospital, Clermont-Ferrand

Unknown

Impact of Early Lactate Dosage Compared to CK for Diagnosis of a Suspected Seizure

Creatine Kinase | Lactate | Epileptic Seizure | Epileptic Generalized Tonic-clonic Seizure

France
The Cooper Health System

Terminated

Study To Establish Maximum Tolerated Dose (MTD) of Cyberknife in Patients With Un-Resectable Pancreas Cancer (TL002)

Pancreatic Cancer | Pancreatic Adenocarcinoma | Pancreas Adenocarcinoma | Pancreas Cancer | Adenocarcinoma of the Pancreas

United States
Cytokinetics

Recruiting

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM (MAPLE-HCM)

Obstructive Hypertrophic Cardiomyopathy (oHCM)

United States, Denmark, Spain, Netherlands, United Kingdom, France, China, Israel, Germany, Italy, Hungary, Canada
Oslo University Hospital

Completed

Comparison of Blood and Crystalloid Cardioplegia

Aortic Stenosis | Myocardial Protection

Norway

Search clinical trials for: CK-3828136, CK-136

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