Search clinical trials for: Drug trial

Total 274224 results

Regeneron Pharmaceuticals

Not yet recruiting

An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting (SPECTRUM-US)

Visual Impairment | Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD) | Wet Age-related Macular Degeneration (AMD)
Sanofi Pasteur, a Sanofi Company

Not yet recruiting

Co-administration Study of an Investigational Live-Attenuated Respiratory Syncytial Virus Vaccine in Infants and Toddlers (CORAL)

RSV Immunization
Complement Theory Inc.

Not yet recruiting

A Randomised Controlled Trial to Evaluate the Impact of Complement Theory's Live 1:1 Exercise Coaching and Personalised Digital Application on Cancer Survivors' Cost of Care

Breast Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer | Other Cancer
West China Hospital

Not yet recruiting

Individualized ANH for Non-cardiac Surgery

Hemodilution | Transfusion Related Complication
CSL Behring

Not yet recruiting

Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Chinese Subjects With Hemophilia B Previously Treated With FIX Therapy

Hemophilia B
McGill University Health Centre/Research Institute...

Not yet recruiting

A Registry-Based Parallel Group Randomized-Controlled Trial of an Upper Limb Exergaming Intervention for Children and Adolescents With Spinal Muscular Atrophy, With an Optional Open-Label Extension (INFORM SMA)

Spinal Muscular Atrophy
Mayo Clinic

Not yet recruiting

Wisconsin Ginseng for Decreasing Cancer Related Fatigue

Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Beijing Hospital of Traditional Chinese Medicine

Not yet recruiting

A Multicentre Randomized Controlled Clinical Study on the Chitosan Nanocrystalline Qinteng Huoxue Runji Ointment Therapy for Psoriasis With Blood Stasis Syndrome.

Plaque Psoriasis
Summit Therapeutics
Akeso

Recruiting

Phase III Study of AK112 for NSCLC Patients

Non-Squamous Non-small Cell Lung Cancer

Canada, United States, Spain, Italy, France
Cairo University

Not yet recruiting

The Effect of Photobiomodulation Using Low-Level Diode Laser Therapy on Postoperative Pain in Symptomatic Lower Molar Teeth With Irreversible Pulpitis and Apical Periodontitis; a Randomized Controlled Clinical Trial

Effect of Photobiomodulation Using Diode Laser
Chinese PLA General Hospital

Not yet recruiting

Chidamide+Decitabine Plus Anti-PD-1 Antibody in PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma.

PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma
Université de Sherbrooke
Hopital Charles Lemoyne

Not yet recruiting

Epsom Salt Compresses to Relieve Perineal for Postpartum Care: A Clinical Trial

Pain | Perineal Injury
Preeyaporn Jirakittidul

Not yet recruiting

The Effect of Dimenhydrinate on Postoperative Nausea and Vomiting After Abdominal Hysterectomy: Randomized-controlled Trial

Healthy Women | Gynecologic Neoplasm
Centre Leon Berard
Groupe Français de Pneumo-Cancérologie

Not yet recruiting

FIRST-NEC (GFPC 01-2022) - Combination of Durvalumab With Etoposide and Platinum (FIRST-NEC)

Large Cell Neuroendocrine Carcinoma of the Lung

France
Washington University School of Medicine

Not yet recruiting

LIMIT Trial - Lidocaine With Intramuscular Injection of Benzathine Penicillin G for Treponema Pallidum Treatment (LIMIT)

Syphilis Infection | Benzathine Penicillin Adverse Reaction
Fundación Pública Andaluza para la Investigación...

Recruiting

SURGERY VS BOTULINUM TOXIN ON QUALITY OF LIFE IN STROKE PATIENTS: RANDOMIZED TRIAL

Stroke

Spain
Genmab
BioNTech SE

Recruiting

Trial to Assess the Safety and Preliminary Efficacy of GEN1055 on Malignant Solid Tumors as Monotherapy and as Combination Therapy

Malignant Solid Tumor

Spain
Hebrew SeniorLife
Beth Israel Deaconess Medical Center; Tufts University; MaineHealth; Solarea Bio...

Not yet recruiting

Synbiotic to Attenuate Resorption of the Skeleton (STARS)

Inflammation | Aging | Osteoporosis

United States
Massachusetts General Hospital
University of Ibadan

Not yet recruiting

Pilot Randomized Clinical Trial of Change My Story

Depression | Hiv | Psychological Distress
Aldeyra Therapeutics, Inc.

Recruiting

A Phase 3 Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease

Dry Eye Disease

Canada
Novo Nordisk A/S

Not yet recruiting

A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight

Obesity

United Kingdom, Germany, Canada, United States, France
Mayo Clinic

Not yet recruiting

Accuracy of 18F-rhPSMA-7.3 PET/ MRI for Prediction of Lymph Node Metastasis in Localized High-Risk Prostate Cancer

Localized Prostate Carcinoma | Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Oligometastatic Prostate Carcinoma

United States
GlaxoSmithKline

Recruiting

A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus (RSV) Given to Adults 18 to 49 Years of Age at Increased Risk for Respiratory Syncytial Virus Disease, Compared to Older Adults 60 Years of Age and Above

Respiratory Syncytial Virus Infections

Canada, Australia, United States, Germany, Japan, South Africa
University of California, San Diego
Mayo Clinic; National Heart, Lung, and Blood Institute (NHLBI); Yale University; Brigham and Women's Hospital and other collaborators

Recruiting

Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping (EPIPHANY)

Moderate to Severe Asthma

United States
Boston Immune Technologies and Therapeutics

Not yet recruiting

A Clinical Trial in Adults With Non-Hodgkin Lymphoma (NHL), With a Particular Emphasis on Cutaneous T Cell Lymphoma (CTCL), Testing the Safety and Activity of a Novel Drug to Inhibit a Protein Called Tumor Necrosis Factor Receptor 2 That Drives Both Lymphoma Growth and Escape of the Immune System

Peripheral T-cell Lymphoma | NHL | Cutaneous T Cell Lymphoma
Opella Healthcare Group SAS, a Sanofi Company

Not yet recruiting

Bioavailability Study of Magne-B6 New Formulation

Healthy Volunteers
Eli Lilly and Company

Not yet recruiting

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES)

Overweight and Obesity

United States, Canada, Australia, Germany, Mexico, Argentina, Brazil, Hungary, Austria, India, Poland, Slovakia, Spain, Netherlands, Turkey, Czechia, United Kingdom, Denmark, Puerto Rico, France, Israel
Chinese SLE Treatment And Research Group
Beijing Life oasis public service center

Not yet recruiting

A Study on the Prevention and Treatment of GIOP With Eldecalcitol (ELEGANT)

Rheumatoid Arthritis | Osteoporosis | Osteopenia

China
Regeneron Pharmaceuticals

Not yet recruiting

Study of Cemiplimab Alone or in Combination With Fianlimab and/or Other Experimental Agents in Adult Participants With Peri-operative Stage III/IV Cutaneous Squamous Cell Carcinoma (CSCC)

Cutaneous Squamous Cell Carcinoma
University of Bern
Swiss National Science Foundation; University of Zimbabwe

Not yet recruiting

The Friendship Bench Plus Trial (FB+)

Major Depressive Disorder | Severe Depressive Episode Without Psychotic Symptoms

Zimbabwe
University Health Network, Toronto

Not yet recruiting

Topical TRanexamic Acid vs. Placebo on Acute Postoperative Pain Following DRF Fixation (TRADR)

Distal Radius Fractures

Canada
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

A Study to Evaluate Pregabalin in Painful Diabetic Peripheral Neuropathy

Painful Diabetic Neuropathy
University Hospital, Tours

Not yet recruiting

Efficacy of EMONO as an add-on Therapy to Conventional Antidepressants for the Treatment of Depressive Symptoms in Nursing-home Residents With Neurocognitive Disorders: a Randomized Controlled Trial- (PROTO-EHPAD)

Depression | Neurocognitive Disorders
McMaster University
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

A Trial of a Next Generation COVID-19 Vaccine Delivered by Inhaled Aerosol (AeroVax)

COVID-19 Infection

Canada
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Bayesian Basket Trial (PALETTE)

Sepsis
Cancer Research UK
UCB Biopharma SRL

Not yet recruiting

A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer

Uterine Cervical Neoplasms | Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Pancreatic Neoplasms | Esophageal Neoplasms | Ovarian Neoplasms | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Neoplasms | Advanced Solid Tumours | Carcinoma, Renal Cell (Clear Cell Only) | Stomach Neoplasms...

United Kingdom
Mayo Clinic
National Cancer Institute (NCI)

Not yet recruiting

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
GlaxoSmithKline

Recruiting

A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults

Influenza, Human

United States
University of Salerno

Not yet recruiting

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients (BESAFE)

Cardiovascular Diseases | Dyslipidemias | Lipid Metabolism Disorders | Statin Adverse Reaction
Montefiore Medical Center

Not yet recruiting

Antiemetic Fosaprepitant To Remedy Nausea and Vomiting (AFTR NV RCT)

Nausea | Vomiting | Nausea and Vomiting

United States
Northwell Health

Recruiting

Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries

Pain, Postoperative | Postoperative Pain, Acute

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Clinical Trial of Microneedle Radiofrequency Combined With Oral Isotretinoin in Moderate to Severe Acne

Moderate to Severe Acne Vulgaris

China
Mayo Clinic

Not yet recruiting

Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial (DIVINE)

Recurrent Prostate Cancer | Castration-resistant Prostate Cancer | Stage IVB Prostate Cancer AJCC v8 | Recurrent Castration-Sensitive Prostate Carcinoma

United States
Shanghai JMT-Bio Inc.

Not yet recruiting

JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations

Local Advanced or Metastatic NSCLC
Bayer

Recruiting

A Study to Learn About How Food and Esomeprazole Affect the Level of BAY2927088 in the Blood When Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United States
JHSPH Center for Clinical Trials
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Multi-Center Clean Air Randomized Controlled Trial in COPD (Clean Air)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Indian Council of Medical Research
King George's Medical University; Lady Hardinge Medical College; King Edward... and other collaborators

Not yet recruiting

Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates (SAUNA)

Sepsis | Preterm Birth | Preterm Premature Rupture of Membrane | PROM, Preterm (Pregnancy) | Early-Onset Neonatal Sepsis

India
University of Michigan Rogel Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

A Trial of Omeprazole and Low Dose Aspirin to Identify Colorectal Biomarkers of Preventive Efficacy

Colorectal Neoplasia

United States
Etienne Xavier Keller

Recruiting

Effect of Propofol vs. Sevoflurane on Erections During Narcosis In Transurethral Surgery (PENIS)

Erection; Incomplete

Switzerland
Vall d'Hebron Institute of Oncology

Recruiting

Status of HRD That Lead to a Benefit From Olaparib in Combination With Bevacizumab (STROBE Trial) (STROBE)

Ovarian Cancer

Spain

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