Search clinical trials for: GABAA receptor

Total 17975 results

The Deutsche Diabetes Forschungsgesellschaft e.V.
Algiax Pharmaceuticals GmbH

Recruiting

Effects of GABAA Receptor Modulation by AP-325 on Insulin Secretion in Patients With Type 2 Diabetes

Type2 Diabetes

Germany
Praxis Precision Medicines

Withdrawn

A Clinical Trial of PRAX-114 in Participants With Essential Tremor

Essential Tremor

United States
Jules Desmeules

Completed

Exploring the Role of the GABAergic Modulation in Pain Transmission in Human (NDMC-101)

Neuropathic Pain

Switzerland
University Hospital, Geneva

Completed

GABAergic Modulation in Pain Transmission in Human: Effect of the GABAA Agonist Clobazam on Peripheral and Central Sensitisation

Neuropathic Pain

Switzerland
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With (11C) Flumazenil to Determine Central GABAA Receptor Occupancy of AZD6280 (PET)

Anxiety

Sweden
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With (11C)Flumazenil to Determine Central GABAA Receptor Occupancy of AZD7325 (PET)

Anxiety

Sweden
Post Graduate Institute of Medical Education and...
Indian Council of Medical Research

Not yet recruiting

Carvedilol + Simvastatin vs. Carvedilol Alone for Chronic Liver Disease and Cirrhotic Cardiomyopathy and Its Impact on Hepatic Decompensation and Survival; a Double-blind Randomized Controlled Trial (CIRROSTAT)

Decompensated Cirrhosis | Acute Kidney Injury | Cirrhosis, Liver | Left Ventricular Diastolic Dysfunction | Cirrhotic Cardiomyopathy
Shenzhen Institute of Advanced Technology, Chinese...

Recruiting

Variation in the Impact of Coffee on the Metabolic Rate

Healthy

China
Radboud University Medical Center
UMC Utrecht; Catharina Ziekenhuis Eindhoven; Maasstad Hospital

Not yet recruiting

Efficacy of Endothelin Receptor Antagonism in Coronary Artery Spasm (EDIT-CAS)

Coronary Spasm

Netherlands
Chong Kun Dang Pharmaceutical

Recruiting

Efficacy and Safety of Telmisartan Compared With Losartan

Hypertension | Diabetic Nephropathies

Korea, Republic of
Auburn University
National Institute on Drug Abuse (NIDA); Wayne State University

Not yet recruiting

Cannabinoids and Biological Reactivity to Stress (COBRAS)

Cannabis Use Disorder
Karamanoğlu Mehmetbey University

Not yet recruiting

Determination of Salivary Soluble Urokinase Plasminogen Activator Receptor (SuPAR), Hypoxia-inducible Factor-1 Alpha (HIF-1α), E-cadherin, Galectin 3, IL-4, IL-10 and TNF-α Levels in Individuals With Different Degrees of Periodontal Disease

Periodontitis | Periodontal Diseases
University of KwaZulu

Not yet recruiting

Anti-Inflammatory Reliever South Africa (AIRSA001)

Asthma
Henry M. Jackson Foundation for the Advancement...
Uniformed Services University of the Health Sciences; Brooke Army Medical Center

Not yet recruiting

Ketamine for Sedation in Severe Traumatic Brain Injury (Ketamine)

Intracranial Hypertension | Severe Traumatic Brain Injury | Intracranial Hemorrhage, Hypertensive
Chih-Hui Chiu

Recruiting

Caffeine & Bodybuilding Dehydration Ability

Caffeine | Placebo

Taiwan
Atara Biotherapeutics

Not yet recruiting

A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Lupus Nephritis

Systemic Lupus Erythematosus | Lupus Nephritis
Merck Sharp & Dohme LLC

Not yet recruiting

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Metastatic Breast Cancer
Ain Shams University

Not yet recruiting

The Effect of Adding Either Propofol or Ketamine to Magnesium and Lidocaine Infusions in Nasal Surgeries.

Intraoperative Bleeding

Egypt
Zhuhai Beihai Biotech Co., Ltd

Not yet recruiting

An Relative Bioavailability Study of BH006 for Injection in Healthy Subjects

Bioavailability
Shenzhen Geno-Immune Medical Institute
The No.2 Clinical Hospital of the Ministry of Health

Recruiting

Frontline Combination CAR-T Cell Therapy for Multiple Myeloma or Plasmacytoma

Multiple Myeloma | Plasmacytoma

China, Russian Federation
National Cancer Institute (NCI)

Not yet recruiting

Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy

Pheochromocytoma | Somatostatin Receptor Positive | Paragangliomas | Gastrointestinal Neuroendocrine Tumors

United States
Universidad de Almeria
Leiden University Medical Center; ETH Zurich (Switzerland)

Not yet recruiting

Deciphering a Novel and Unique Brown Adipose Tissue Depot in Women (DEBATE)

Cardiometabolic Diseases

Spain
Ewha Womans University Seoul Hospital

Not yet recruiting

Comparison of the Improvement and Safety of the Ankle Brachial Arterial Pressure Index of Sarpogrelate and Clopidogrel in Stroke Patients With Decreased Ankle Brachial Arterial Pressure Index and Intermittent Claudication of Lower Limb Vascular Atherosclerosis.

Stroke | Atherosclerosis
Stanford University
American Heart Association

Not yet recruiting

Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries (MVP-ANOCA)

Angina Pectoris | Microvascular Angina | Vasospastic Angina | Myocardial Bridge of Coronary Artery

United States
Medical University of South Carolina

Not yet recruiting

Study of Fingolimod

Non Small Cell Lung Cancer | Small-cell Lung Cancer
Tanta University

Recruiting

Preoperative Ondansetron Lozenge for Prevention of Postoperative Nausea and Vomiting in Pediatrics Undergoing Squint Surgeries

Postoperative Nausea and Vomiting | Pediatrics | Squint | Ondansetron Lozenge

Egypt
Tanta University

Recruiting

Preoperative Ondansetron Lozenge for Prevention of Post-Spinal Shivering in Caesarean Section

Cesarean Section | Ondansetron Lozenge | Post-Spinal Shivering

Egypt
Bostal Drug Delivery Co., Ltd

Not yet recruiting

A Study to Evaluate Safety, Tolerability and pK of Semaglutide ER Injectable Suspension in Healthy, Adult Human Subjects

Diabetes Mellitus, Type 2
AstraZeneca
Premier HealthCare Solutions Inc.

Recruiting

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care (ANCHOR)

Asthma

United States
Benha University

Recruiting

Articaine Plus Dexmedetomidine in Supraclavicular Block

Post Operative Pain, Acute

Egypt
Jens D Hove, MD,PHD

Recruiting

Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure (FIT-HF)

Obesity | Weight Loss | Chronic Heart Failure | Heart Failure With Reduced Ejection Fraction

Denmark
Icahn School of Medicine at Mount Sinai

Not yet recruiting

Intrathecal Dexmedetomidine vs Epinephrine

Cesarean Section | Anesthesia, Spinal

United States
Vittoria Biotherapeutics
University of Pennsylvania

Not yet recruiting

CD5-deleted Chimeric Antigen Receptor Cells (Senza5 CART5) for T Cell Non-Hodgkin Lymphoma (NHL) (VIPER101)

T Cell Non-Hodgkin Lymphoma

United States
Institute of Liver and Biliary Sciences, India
Institute of Liver and Biliary Sciences

Recruiting

Effect of TCI Propofol on Liver Transplant (TCI) Propofol on Intra-operative Usage of Vasopressors in Liver Transplant Recipients.

Liver Transplant Recipients

India
Acepodia Biotech, Inc.

Not yet recruiting

ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)

Metastatic Solid Tumor | Locally Advanced Solid Tumor

United States
Anqing Municipal Hospital

Recruiting

The Effect of Dexmedetomidine and Esketamine Combined Infusion Quality of Sleep Undergoing Modified Radical Mastectomy

Dexmedetomidine Plus Esketamine Affect Postoperative Sleep Quality

China
Hansoh BioMedical R&D Company

Not yet recruiting

A Study of HS-20117 Combined With Aumolertinib in Participants With Advanced Non-Squamous Non-Small Cell Lung Cancer

Non-Squamous Non-Small Cell Lung Cancer
PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Not yet recruiting

Preliminary Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Systemic Sclerosis | Immune Thrombocytopenia | Sjogren's Syndrome | Idiopathic Inflammatory Myopathies | Primary Biliary Cholangitis
University of Oxford

Recruiting

Baby-CINO: CaffeINe Treatment Optimisation in Premature Infants (Baby-CINO)

Caffeine | Infant,Premature

United Kingdom
AstraZeneca
Daiichi Sankyo

Not yet recruiting

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung15)

Metastatic Non-small Cell Lung Cancer
Theodor Bilharz Research Institute

Recruiting

The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study

Procedural Sedation | GIT Endoscopy

Egypt
Fujian Provincial Hospital
Fujian Maternity and Child Health Hospital; Fujian Children's Hospital

Not yet recruiting

Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children

Behavior Problem
Axsome Therapeutics, Inc.

Recruiting

Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol (ENGAGE)

Binge-Eating Disorder

United States
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Novo...

Not yet recruiting

Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment

Obesity | Diabetes type1

United States
Muhammad Ilyas

Not yet recruiting

Impact of Intrathecal vs Intravenous Dexmedetomidine

Nausea and Vomiting, Postoperative
Jules Bordet Institute
RayzeBio, Inc.

Not yet recruiting

A Phase I Study to Assess the Tolerability of 225Ac-DOTATATE in Patients With Refractory and Relapsing Multiple Myeloma Expressing Somatostatin Receptors (AcTRESS)

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory | Multiple Myeloma Progression

Belgium
Assiut University

Not yet recruiting

Dexmeditomedine as an Adjuvant to Levobupivacaine in Transversus Thoracis Plane Block on the Management of Post-sternotomy Pain in Open-heart Surgeries

Pain, Postoperative
Centre for Human Drug Research, Netherlands

Recruiting

Deep Phenotyping of Cutaneous Lupus Erythematosus

Cutaneous Lupus Erythematosus

Netherlands
QED Therapeutics, Inc.

Recruiting

Prospective Clinical Assessment Study in Children With Hypochondroplasia (HCH)

Hypochondroplasia

United States, Australia, Norway, Portugal, Singapore, Spain
University Medical Center, Kazakhstan
Nazarbayev University; Astana Medical University; Ministry of Science and Higher... and other collaborators

Recruiting

Effectiveness of Weight Loss Methods on Lifespan for Metabolic Syndrome

Metabolic Syndrome

Kazakhstan

Search clinical trials for: GABAA receptor

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