- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06431035
Caffeine & Bodybuilding Dehydration Ability
July 23, 2024 updated by: Chih-Hui Chiu
Effect of Caffeinated Chewing Gum on Dehydration Ability in Bodybuilding Athletes: a Crossover Trial
15-20 trained bodybuilding athletes were divided into caffeine gum trial (CAF) and placebo trial (PL) with a randomized, double-blind study design.
The participants chewing either caffeine Gum (CAF trial, containing 5 mg/kg of caffeine) or placebo gum (PL) for 10 minutes.
After rested for 15 minutes, Participants used the bicycle to adjust the pedal resistance and speed according to their own feelings until they were dehydrated to 2% of their original body weight.
Study Overview
Detailed Description
The purpose of this study was to investigate the effect of caffeinated chewing gum on dehydration ability in bodybuilding athletes.
Methods: 15-20 trained bodybuilding athletes were divided into caffeine gum trial (CAF) and placebo trial (PL) with a randomized, double-blind study design.
The participants chewing either caffeine Gum (CAF trial, containing 5 mg/kg of caffeine) or placebo gum (PL) for 10 minutes.
After rested for 15 minutes, Participants used the bicycle to adjust the pedal resistance and speed according to their own feelings until they were dehydrated to 2% of their original body weight.
Record time from exercise to completion of dehydration, heart rate, HRV, energy expenditure, fat oxidation rate and carbohydrate oxidation rate.
Study Type
Interventional
Enrollment (Actual)
14
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Taichung, Taiwan, 404
- National Taiwan University of Sport
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- having won the top 8 places in a national competition,
- having no cardiovascular or joint diseases
- being an adult male
Exclusion Criteria:
- no top 8 finishes at national level
- cardiovascular or joint disease, or any other condition that could be impaired by exercise
- female and underage participants
- previous caffeine allergy
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: caffeine gum
Chewing caffeine Gum (CAF trial, containing 5 mg/kg of caffeine) for 10 minutes before test.
|
The participants chewed either caffeine gum (5 mg/kg for 10 minutes per chew) or a placebo (10 minutes per chew, using regular gum).
Other Names:
|
|
Placebo Comparator: placebo
Chewing placebo gum (without caffeine) for 10 minutes before test.
|
The participants chewed either caffeine gum (5 mg/kg for 10 minutes per chew) or a placebo (10 minutes per chew, using regular gum).
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
dehydration speed
Time Frame: 15 minutes after intervention
|
The participants start dehydration until dehydrated to 2% of their original body weight.
|
15 minutes after intervention
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
energy expenditure
Time Frame: 15 minutes after intervention
|
The energy expenditure during dehydration
|
15 minutes after intervention
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: ChihHui Chiu, PhD, National Taiwan University of Sport
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
April 8, 2024
Primary Completion (Actual)
June 30, 2024
Study Completion (Actual)
June 30, 2024
Study Registration Dates
First Submitted
April 8, 2024
First Submitted That Met QC Criteria
May 24, 2024
First Posted (Actual)
May 28, 2024
Study Record Updates
Last Update Posted (Actual)
July 24, 2024
Last Update Submitted That Met QC Criteria
July 23, 2024
Last Verified
July 1, 2024
More Information
Terms related to this study
Additional Relevant MeSH Terms
- Pathologic Processes
- Metabolic Diseases
- Water-Electrolyte Imbalance
- Dehydration
- Physiological Effects of Drugs
- Neurotransmitter Agents
- Molecular Mechanisms of Pharmacological Action
- Enzyme Inhibitors
- Purinergic Antagonists
- Purinergic Agents
- Phosphodiesterase Inhibitors
- Purinergic P1 Receptor Antagonists
- Central Nervous System Stimulants
- Caffeine
Other Study ID Numbers
- 113-3 (Other Identifier: NTUS)
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
IPD Plan Description
Only participant number and experimental data are provided.
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Caffeine
-
Ain Shams UniversityCompletedCaffeine | Caffeine Withdrawal | Caffeine DependenceEgypt
-
Psychiatric Hospital of the University of BaselSwiss National Science FoundationCompletedSleep | Circadian Rhythm | Caffeine | Caffeine WithdrawalSwitzerland
-
St. Mary's University, TwickenhamNot yet recruiting
-
St Mary's University CollegeNot yet recruiting
-
Ege UniversityThe Scientific and Technological Research Council of TurkeyCompletedCaffeineTurkey (Türkiye)
-
Wake Forest University Health SciencesThe Hershey CompanyCompleted
-
Technical University of LisbonCompleted
-
Johns Hopkins UniversityNational Institute on Drug Abuse (NIDA)CompletedSleep Disorder | Diarrhea | Anxiety Disorders | Insomnia | Sleep Initiation and Maintenance Disorders | Anxiety | Sleep Disturbance | Gastrointestinal Dysfunction | Heartburn | Caffeine | Caffeine Withdrawal | Caffeine; Sleep Disorder | Caffeine Dependence | Caffeine-Induced Anxiety Disorder | Caffeine-Induced Sleep... and other conditionsUnited States
-
St. Mary's University, TwickenhamNot yet recruiting
-
Yu-Shiuan LinActive, not recruiting
Clinical Trials on caffeine
-
University of RochesterNot yet recruitingInfants | Neonatal Apnea
-
Indiana UniversityIndiana Clinical and Translational Sciences InstituteNot yet recruitingPremature Birth | Respiratory Distress Syndrome | Bronchopulmonary Dysplasia | Apnea of Prematurity | Preterm Labor With Preterm Delivery
-
Northumbria UniversityCompletedExercise | Dietary SupplementTurkey (Türkiye)
-
Sinop UniversityCompletedAthletic Performance | Cognitive Performance | Healthy Adult FemalesTurkey (Türkiye)
-
Istanbul University - Cerrahpasaİstanbul Yeni Yüzyıl ÜniversitesiNot yet recruitingMuscle Strength | Exercise Performance | Adaptation | Muscle HypotrophyTurkey (Türkiye)
-
KTO Karatay UniversityRecruitingPostoperative Pain | Gastrointestinal Motility | Psychological Well-BeingTurkey (Türkiye)
-
Universidad Rey Juan CarlosEnrolling by invitationExercise | Caffeine | Ergogenics | Cycling | Fat MetabolismSpain
-
Southern Illinois University CarbondaleCompleted
-
National Taiwan Sport UniversityCompleted
-
University of Wisconsin, MadisonEunice Kennedy Shriver National Institute of Child Health and Human Development...Recruiting