Search clinical trials for: Heavy water

Total 6371 results

UK Kidney Association

Recruiting

National Registry of Rare Kidney Diseases (RaDaR)

Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy | Atypical Hemolytic Uremic Syndrome | Autosomal Dominant Polycystic Kidney Disease | Cystinosis | Nephronophthisis | BK Nephropathy and other conditions

United Kingdom
National Cancer Institute (NCI)

Recruiting

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Hormone Receptor-Positive Breast Carcinoma | HER2-Negative Breast Carcinoma

United States
Columbia University
University of California, Berkeley

Recruiting

Glycemic Effect of Diazoxide in NAFLD

Insulin Resistance | Prediabetic State | Hyperinsulinemia | Non-Alcoholic Fatty Liver Disease

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-small Cell Lung Cancer

Stage III Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Locally Advanced Lung Non-Small Cell Carcinoma

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Recruiting

Regorafenib and Durvalumab for the Treatment of High-Risk Liver Cancer

Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IB Hepatocellular Carcinoma AJCC v8 | Stage II Hepatocellular Carcinoma AJCC v8

United States
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

Endometrial Mixed Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Stage IV Uterine Corpus Cancer AJCC v8 | Endometrial Adenocarcinoma | Endometrioid Adenocarcinoma

United States, Canada
National Cancer Institute (NCI)

Active, not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Glioma | Hematopoietic and Lymphoid Cell Neoplasm | Melanoma | Lymphoma | Multiple Myeloma | Recurrent Ovarian Carcinoma | Breast Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Skin Carcinoma | Gastric Carcinoma | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory... and other conditions

United States, Puerto Rico, Guam
National Cancer Institute (NCI)
NRG Oncology; Canadian Cancer Trials Group

Active, not recruiting

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage... and other conditions

United States, Canada
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

Stage III Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Unresectable Lung Non-Small Cell Carcinoma | Recurrent Lung Non-Small Cell Carcinoma

United States, Guam
OHSU Knight Cancer Institute
Oregon Health and Science University

Terminated

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Primary Myelofibrosis | Anemia | Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Anatomic Stage IV Breast Cancer AJCC v8 | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic... and other conditions

United States
Johns Hopkins Bloomberg School of Public Health
Columbia University; Missouri Breaks Industries Research, Inc.

Active, not recruiting

Strong Heart Water Study (SHWS)

Arsenic Poisoning

United States
National Cancer Institute (NCI)

Active, not recruiting

Durvalumab and Tremelimumab With or Without High or Low-Dose Radiation Therapy in Treating Patients With Metastatic Colorectal or Non-small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Colorectal Carcinoma | Stage IV Lung Non-Small Cell Cancer AJCC v7

United States, Canada
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
SWOG Cancer Research Network
National Cancer Institute (NCI)

Completed

Durvalumab and Tremelimumab in Treating Patients With Recurrent Stage IV Lung Cancer

Recurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Completed

Lung-MAP: Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer

Recurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7

United States, Canada
SWOG Cancer Research Network
National Cancer Institute (NCI)

Completed

Lung-MAP: Durvalumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers

Recurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7

United States
University of Waterloo
Alcon Research

Completed

Evaluating the Performance of Precision1 Daily Disposable Contact Lens in a Group of Heavy Digital Device Users (PUG)

Myopia

Canada
Boston Medical Center
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers

Alcohol Use Disorder

United States
Lia Bally

Completed

Assessing Insulin Turnover Using an In-vivo Deuterated Water Experiment. (DEEP1A)

Hypoglycemia | Gastric Bypass | Bariatric Surgery

Switzerland
University of Nottingham
Abbeyfield

Completed

Concurrent Assessment of Skeletal Muscle Mass and Synthesis/Breakdown in Old Age

Sarcopenia | Muscle Atrophy

United Kingdom
M.D. Anderson Cancer Center
Pharmacyclics LLC.

Completed

Pilot Study to Determine Effects of the Btk Inhibitor PCI-32765 on Leukemia Cell Kinetics and Trafficking, Using Heavy Water Labeling in Subjects With CLL and SLL

Leukemia

United States
Philip Kern
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Cold Induced Changes in White Adipose

Metabolic Syndrome | Obese | Prediabetes | Normal Body Weight

United States
Gazi University

Completed

Comparing the Effects of Levobupivacaine and Bupivacaine in Saddle Spinal Anesthesia

Drug Effect | Anesthesia | General Surgery | Outpatients | Anorectal Disorder
Göteborg University
Sahlgrenska University Hospital, Sweden

Completed

Effect of Body Weight Loading on Urinary Electrolyte Excretion (EBU)

Obesity | Edema

Sweden
Ulthera, Inc

Completed

Feasibility Study: Heavy Water Tissue Labeling Protocol

Skin Laxity

United States
University of Saskatchewan
University of Chicago; Emory University; University of Alberta; University of Calgary and other collaborators

Completed

Selenium and Arsenic Pharmacodynamics (SEASP)

Arsenic Poisoning Chronic

Bangladesh
GlaxoSmithKline

Terminated

Study to Evaluate Fractional Collagen Synthesis Within Keloid Scars and Identify Biomarkers of Keloid Scars

Fibrosis

United Kingdom
Pennington Biomedical Research Center
Tanita

Completed

Tanita BIA System Validation (Tanita)

Body Composition | Circumference Measurements | Tissue Thickness Measurements

United States
University of Nottingham
Physiological Society

Completed

The Implementation of Novel 'Heavy' Water Techniques for Determining Modulation of Muscle Protein, DNA and Lipid Synthesis Due to Ageing

Healthy

United Kingdom
Centre for Addiction and Mental Health

Completed

Dopamine Release in the Human Brain Following Alcohol Administration

Heavy Drinking

Canada
Salena Killion
Michael J. Fox Foundation for Parkinson's Research

Unknown

Using Heavy Water to Study Cell Dynamics in Parkinson's Disease

HIV Infections | Parkinson's Disease

United States
KineMed
Bristol-Myers Squibb

Completed

Evaluating Cerebrospinal Fluid Biomarkers in Alzheimer's, Progressive Supranuclear Palsy Subjects, and Controls

Alzheimer Disease | Progressive Supranuclear Palsy

United States
Texas Tech University
National Cancer Institute (NCI); American Cancer Society, Inc.

Completed

Selenium in the Treatment of Arsenic Toxicity and Cancers (SETAC)

Arsenical Melanosis | Arsenical Keratosis | Arsenical Cancers | Arsenicosis | Arsenic Exposure | Arsenic Toxicity | Arsenic Poisoning

Bangladesh
Arizona State University

Not yet recruiting

Rehydration Efficiency During Ad-libitum Fluid Intake (LIV-D2O)

Dehydration

United States
Toronto Metropolitan University
McMaster University; University of Guelph; University of Waterloo; Health Canada; Public Health Agency of Canada (PHAC) and other collaborators

Recruiting

Canadian Beach Cohort Study

Gastrointestinal Diseases | Water-Related Diseases

Canada
EuBiologics Co.,Ltd

Not yet recruiting

Clinical Trial to Evaluate EuHZV in Healthy Adults Aged 50 to 69 Years

Herpes Zoster | Varicella Zoster Virus Infection
University of Cologne

Recruiting

Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges (RESERVE)

Hyponatremia

Germany
Guangdong Provincial People's Hospital

Recruiting

Pulmonary Watershed Topographic Map Navigation for Lung Nodule Resection

NSCLC, Stage I | Disease Free Survival | Pulmonary Function Assessment

China
HoHo Biotech
Tri-Service General Hospital; Taoyuan Armed Forces General Hospital

Recruiting

To Evaluate the Efficacy of Oral Molecular Hydrogen Supplement in Patients With Chronic Diseases

Chronic Disease | Chronic Inflammation

Taiwan
University of British Columbia

Recruiting

Impact of Exercise Intensity on Fitness, Extracellular Vesicles, Inflammation, and Metabolism (CEX)

Exercise Training

Canada
Université de Sherbrooke
Hopital Charles Lemoyne

Not yet recruiting

Epsom Salt Compresses to Relieve Perineal for Postpartum Care: A Clinical Trial

Pain | Perineal Injury
University of Pittsburgh
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

Centering Gender Affirming Resources in Higher Education (CARE)

Sexual Violence | Drinking Heavy

United States
Rocky Vista University, LLC

Recruiting

Ultrasound Investigation Into Swimming Induced Pulmonary Edema in Open Water Swimming Athletes (SIPE)

Swimming Induced Pulmonary Edema

United States
Kantonsspital Winterthur KSW
Luzerner Kantonsspital

Not yet recruiting

Skin Cancer and Hyperthermia and Radiotherapy (SAHARA)

Basal Cell Carcinoma | Non-melanoma Skin Cancer | Squamous Cell Carcinoma Skin

Switzerland
University Hospital, Basel, Switzerland

Not yet recruiting

Validation of New Diagnostic Indices to Simplify Hyponatremia Therapy Assessment in Patients on Thiazide Diuretics

Thiazide Associated Hyponatremia

Switzerland
Indonesia University
Universitas Padjadjaran; Fakultas Kedokteran Universitas Indonesia; Institut... and other collaborators

Not yet recruiting

The Effect of Anthocyanin Intake From Purple Sweet Potato in Cerebral Small Vessel Disease

Cerebral Small Vessel Diseases
VA Office of Research and Development

Not yet recruiting

Personalized Approach Bias Modification in Heavy Drinking Veterans With Mild to Moderate Traumatic Brain Injury (TABM)

Alcohol Use Disorder | Mild-Moderate Traumatic Brain Injury

United States
The Water Street Collective
British American Tobacco (Investments) Limited; HCD Research

Not yet recruiting

A Study to Assess the Effects of Dietary Supplement Drinks on Sleep, Stress and Mood

Stress | Sleep | Mood

United States
University of Waterloo
Alcon Research

Not yet recruiting

Visual Performance of Dailies Total1 Multifocal and Acuvue Oasys Max 1-Day Multifocal in Presbyopic Lens Wearers (GIRAFFE)

Presbyopia

Canada
University Hospital, Montpellier

Recruiting

Perineal Trauma After Jet Ski Accidents and Long-term Functional Outcomes Results (TP-JET)

Anal Incontinence | Perineum; Tear, Traumatic | Anal Tear

France

Search clinical trials for: Heavy water

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