Search clinical trials for: Heme Oxygenase

Total 4289 results

Hillhurst Biopharmaceuticals, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

A Safety, Efficacy, and Pharmacokinetic (PK) Study of HBI-002, an Oral Carbon Monoxide (CO) Therapeutic, in Subjects With Sickle Cell Disease (SCD)

Anemia, Sickle Cell

United States
University of Maryland, Baltimore

Recruiting

Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

Liver Cancer

United States
Ataturk University

Completed

The Effects of Two Anesthetic Drugs on Some Enzyme Levels in Patients Undergoing Lower Extremity Surgery

Malondialdehyde | C-Reactive Protein | Heme Oxygenase

Turkey
Hillhurst Biopharmaceuticals, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Study to Assess the Safety and Pharmacokinetics of HBI-002, an Oral Carbon Monoxide Therapeutic, in Healthy Volunteers

Anemia, Sickle Cell

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...
The Cleveland Clinic

Completed

Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen (PRECISION)

Arthritis, Rheumatoid

United States, Taiwan, Philippines, Mexico, Canada, Australia, Colombia, Brazil, Ukraine, Costa Rica, Hong Kong, Panama, Peru
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

GI-Reasons- A Trial Of GI Safety Of Celecoxib Compared With Non-Selective Nonsteroidal Antiinflammatory Drugs (NSAIDS) (GI-REASONS)

Osteoarthritis

United States, Puerto Rico
Martin Andreas, M.D.
National Bank of Austria; Orphan Medical

Completed

The Effects of Intravenous Heme Arginate on Heme Oxygenase-1 Expression (HO-1) and Oxidative Stress in the Human Heart

Myocardial Ischemia

Austria
Yeditepe University Hospital

Completed

Relationship Between Heme Oxygenase 1 Enzyme Level and Coronary SYNTAX Score

Coronary Artery Disease | Oxidative Stress

Turkey
InfaCare Pharmaceuticals Corporation, a Mallinckrodt...

Completed

Observational Follow-up of Participants From Clinical Trial 64,185-202 (NCT00850993)

Jaundice | Neonatal Hyperbilirubinemia
Daniel Doberer

Completed

Reresveratrol Administered to Healthy Male Subjects (REVAHS)

Healthy Subjects | Heme Oxygenase

Austria
Radboud University Medical Center

Completed

The Effects of Atazanavir-induced Hyperbilirubinemia During Human Endotoxemia

Sepsis | Inflammation | Endotoxemia | Multi Organ Dysfunction Syndrome

Netherlands
University of Edinburgh
NHS Lothian

Completed

Induction of HO-1; a Therapeutic Approach to Reduce Ischaemia Reperfusion Injury (IRI) Following Deceased Donor Renal Transplantation (HOT)

Ischemia-reperfusion Injury | Graft Failure

United Kingdom
Adil Bharucha
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

Modulation of Heme Oxygenase 1 by Nizatidine and Lisinopril in Healthy Subjects

Gastroparesis

United States
Southern California Institute for Research and...

Unknown

Role of Heme-oxygenase (HO) and Nitric Oxide (NO) Pathway in Patients With Obstructive Sleep Apnea (OSA) and Pulmonary Hypertension (PH)

Obstructive Sleep Apnea | Pulmonary Hypertension
Daniel Doberer

Completed

The Effects of Oral Curcumin on Heme Oxygenase-1 (HO-1) in Healthy Male Subjects (CUMAHS)

Healthy

Austria
Daniel Doberer

Completed

Effects of Heme Arginate in Healthy Male Subjects (HEMAHS)

Healthy Subjects | Genetic Polymorphism | Heme Oxygenase

Austria
Radboud University Medical Center
Dutch Diabetes Research Foundation

Terminated

Heme Oxygenase (HO) Activity and Adenosine Induced Vasodilation

Atherosclerotic Cardiovascular Disease

Netherlands
University Medical Center Groningen

Completed

Does Heme Oxygenase-1 Induction Ameliorate Cardiac Injury After Myocardial Infarction? (HAEM)

Acute Myocardial Infarction

Netherlands
Tel-Aviv Sourasky Medical Center

Unknown

Analysis of Anti-inflammatory and Antioxidant Pathways in Lung Diseases by Haem Oxygenase-1 (HO-1) in Induced Sputum and Carbon Monoxide (CO) in Exhaled Air

Lung Diseases
Tel-Aviv Sourasky Medical Center

Unknown

Correlation of Particulate Matter and Heme Oxygenase-1 Protein Activity in Asthmatic Children by Induced Sputum Analysis.

Asthma

Israel
Mayo Clinic

Completed

Hemin in Healthy Subjects

Healthy Volunteers

United States
Charles University, Czech Republic
IGA MZ, Czech Republic

Unknown

Role of Heme Oxygenase in the Pathogenesis of Hepatocellular Injury in Chronic Hepatitis C Virus (HCV) Infection

Nonalcoholic Steatohepatitis | Chronic HCV Infection

Czech Republic
Groningen Research Institute for Asthma and COPD

Completed

Regulatory T Cells in COPD

Chronic Obstructive Pulmonary Disease

Netherlands
Bayer

Not yet recruiting

A Study to Learn About Whether BAY H006689 Causes an Allergic Reaction When Applied as a Topical Gel in Healthy Participants

Pain | Healthy Volunteers

United States
Instituto Nacional de Investigacao em Saude, Angola
FUNDAÇAO CALOUSTE GULBENKIAN; FUNDACIÓN BANCARIA CAIXA D'ESTALVIS I PENSIONS... and other collaborators

Recruiting

LEARNER- Low dosE AspiRiN prEterm tRial (Angola) (LEARNER)

Pregnancy Complications | Pregnancy Related | Sickle Cell Disease | Pre-Eclampsia

Angola
Bruno Minotti
Roland Bingisser, Principal Investigator, Head of Emergency Department, University... and other collaborators

Not yet recruiting

Open-Label Placebo for Non-Specific Pain in the ED (OLP_EM)

Pain, Acute
University of Pennsylvania
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Not yet recruiting

APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia (APPLE)

Pre-Eclampsia | Pregnancy Loss

United States
Riadh Boukef

Recruiting

Enantyum® IV Versus Piroxen® IM in Emergency Pain Management (PiDex)

Traumatic Injury

Tunisia
Federal State Budgetary Institution, V. A. Almazov...

Recruiting

Prospective, Post-registration, Interventional, Randomized, in Parallel Groups, Multicenter Eurasian Clinical Study of DERIVO®/DERIVO® Mini Aneurysm Embolization Device, Europe-Asia

Intracranial Aneurysm

Russian Federation
Muhammad Ilyas

Not yet recruiting

The Effect of Pregabalin and Etoricoxib on Pain Alone Versus in Combination

Back Pain Lower Back Chronic
ASST Fatebenefratelli Sacco

Not yet recruiting

A Study to Investigate the Analgesic Efficacy of Ibuprofen Alone and Ibuprofen Plus Hyoscine-n- Butyl Bromide in Reducing Pain of Outpatient Hysteroscopy

Pain
Western Michigan University School of Medicine
Bronson Methodist Hospital

Not yet recruiting

Haloperidol for Pain Control in Patients With Acute Musculoskeletal Back Pain in the Emergency Department

Back Pain | Chronic Pain
London Health Sciences Centre
Western University

Not yet recruiting

Use of 81 vs 325mg of ASA in Treatment of BCVI

Carotid Artery Injuries | Traumatic Injury | Vertebral Artery Injury
Centre Hospitalier Universitaire, Amiens
University Hospital, Rouen; University Hospital, Lille

Recruiting

Non-steroidal Anti-inflammatory in Cardiac Surgery (KETOPAIN)

Cardiac Surgery | Acute Postoperative Pain | Pain Intensity | Multimodal Pain Management | Non-steroidal Anti-inflammatory Drugs

France
Northwell Health

Recruiting

Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries

Pain, Postoperative | Postoperative Pain, Acute

United States
HALEON

Recruiting

A Real-World Evidence Study to Evaluate the Effects of Voltaren Use on Mobility and Quality of Life in Participants With Knee Osteoarthritis Pain

Pain

United States, Poland
University of Michigan Rogel Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

A Trial of Omeprazole and Low Dose Aspirin to Identify Colorectal Biomarkers of Preventive Efficacy

Colorectal Neoplasia

United States
The Cleveland Clinic

Not yet recruiting

NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow

Chronic Pain | Elbow Pain

United States
Virginia Commonwealth University

Not yet recruiting

Oral Azacitidine in Transplant-Eligible Patients With Acute Myeloid Leukemia (AML) Suffering From Health-Inequality (REMAIN1)

Acute Myeloid Leukemia

United States
Egymedicalpedia

Recruiting

Management of Abnormal Uterine Bleeding

Abnormal Uterine Bleeding

Egypt
Dow University of Health Sciences

Recruiting

Valacyclovir Monotherapy in Pain Management of Acute Periapical Abscesses After Emergency Chamber Opening (Antiviral)

Acute Apical Abscess

Pakistan
Matthew Varacallo
Pacira Biosciences

Not yet recruiting

Impact of Opioid Avoidance Protocol for ACL Reconstruction

Post Operative Pain | ACL Tear

United States
Ain Shams University

Not yet recruiting

Comparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical Healing

Periapical Disease

Egypt
Suez Canal University

Not yet recruiting

Intracutaneous Sterile Water and Diclofenac Sodium Injections in Renal Colic

Renal Colic
Sound Pharmaceuticals, Incorporated
Med-El Corporation

Not yet recruiting

SPI-1005 in Adults Receiving Cochlear Implant

Hearing Loss | Cochlear Trauma
International Bio service

Not yet recruiting

Bioequivalence Study of Generic Celecoxib 200 mg Capsules

Healthy Volunteer
Anhui Medical University

Recruiting

Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study

Cognitive Impairment | Intracranial Atherosclerosis | Cerebrovascular Event

China
Boston Children's Hospital

Recruiting

Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery

Pain | Emergence Delirium | Anesthesia | Tonsillitis | Opioid Analgesic Adverse Reaction | Post-operative Nausea and Vomiting (PONV)

United States
Guangdong Provincial Hospital of Traditional Chinese...

Not yet recruiting

Efficacy and Mechanism of FSN Treatment for Senile Knee Osteoarthritis

Osteoarthritis, Knee
Beijing Tiantan Hospital

Not yet recruiting

Ultrasound-guided Stellate Ganglion Block for Treatment of Chronic Migraine in Adult

Chronic Migraine

China

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