Search clinical trials for: LAL deficiency

Total 10703 results

Cairo University

Recruiting

Vascularized Inter-positional Periosteal Connective-tissue Flap Versus Collagen Membrane in Guided Bone Regeneration (VIP-CT)

Horizontal Ridge Deficiency

Egypt
Alexion

Recruiting

Lysosomal Acid Lipase (LAL) Deficiency Registry (ALX-LALD-501)

Wolman Disease | Cholesterol Ester Storage Disease | Lysosomal Acid Lipase Deficiency | Acid Cholesteryl Ester Hydrolase Deficiency, Type 2 | Acid Lipase Deficiency | LIPA Deficiency | LAL-Deficiency

France, Belgium, United States, Spain, Germany, Greece, Israel, Italy, Slovenia, United Kingdom, Brazil, Canada, Denmark, Australia, Croatia, Czechia, Ireland, Mexico, Netherlands, Poland, Portugal, Saudi Arabia
ViiV Healthcare
Pfizer

Completed

Prospective Observational Epidemiologic Study of Maraviroc's Safety (POEM)

Human Immunodeficiency Virus

United States, Canada, Spain, Belgium, France, United Kingdom, Italy, Brazil, Puerto Rico, Germany, Greece
Alexion Pharmaceuticals

Completed

Acid Lipase Replacement Investigating Safety and Efficacy (ARISE) in Participants With Lysosomal Acid Lipase Deficiency (ARISE)

Lysosomal Acid Lipase Deficiency

France, Poland, United Kingdom, Spain, Mexico, Turkey, Japan, Australia, Russian Federation, United States, Germany, Italy, Czechia, Argentina, Croatia
Alexion Pharmaceuticals

Completed

Safety and Efficacy Study of Sebelipase Alfa in Participants With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency

Spain, Germany, Italy, United States, Croatia, Canada, Russian Federation, Denmark, United Kingdom, Belgium, Mexico, Australia, Netherlands, Brazil, Turkey
Alexion Pharmaceuticals

Terminated

Clinical Study In Infants With Rapidly Progressive Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency

United Kingdom, Finland, United States, Italy
Alexion Pharmaceuticals

Completed

Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Sebelipase Alfa in Children With Growth Failure Due to Lysosomal Acid Lipase Deficiency

Wolman Disease | Lysosomal Acid Lipase Deficiency

United Kingdom, France, United States, Egypt, Ireland
Alexion Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of SBC-102 (Sebelipase Alfa) in Adult Participants With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency | Cholesterol Ester Storage Disease(CESD) | LAL-Deficiency

France, United States, United Kingdom, Czechia
Alexion Pharmaceuticals

Completed

Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of SBC-102 (Sebelipase Alfa) in Adult Subjects With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency | LAL-Deficiency | Cholesterol Ester Storage Disease (CESD)

France, United Kingdom, United States, Canada, Czechia
Wellcome Trust Liverpool Glasgow Centre for Global...
Professor David Lalloo; Professor Hamish Simpson; Professor William J Harrison; Professor Sithombo Maqungo

Unknown

HIV in Orthopaedic Skeletal Trauma Study (HOST)

Fracture Healing in HIV-positive Patients

South Africa
Ankara University
Alexion Pharmaceuticals

Completed

National Lysosomal Acid Lipase Deficiency Study (LAL-D)

Cholesteryl Ester Storage Disease

Turkey
Alexion Pharmaceuticals

Terminated

Screening for Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency

United States
Hospices Civils de Lyon

Unknown

Assessment of the Prevalence of Lysosomal Acid Lipase Deficiency in Patients Waiting for a Liver Transplant. (LALTH-1)

Patients Waiting for a Liver Transplant.

France
Hospices Civils de Lyon

Unknown

Assessement of the Prevalence of Lysosomal Acid Lipase Deficiency in Liver Post-transplant Patients (LALTH-2)

Liver Post-transplant Patients

France
Alexion Pharmaceuticals

Completed

An Observational Study of Patients With Lysosomal Acid Lipase Deficiency/Cholesteryl Ester Storage Disease Phenotype

Lysosomal Acid Lipase Deficiency | Cholesterol Ester Storage Disease(CESD)

United States, United Kingdom, France, Canada, Czech Republic, Italy, Poland, Switzerland
Alexion

Completed

A Retrospective Natural History Study of Patients With Lysosomal Acid Lipase Deficiency/Wolman Phenotype

Wolman Disease | Lysosomal Acid Lipase Deficiency

United States, Canada, United Kingdom, Italy, France
Alexion Pharmaceuticals

No longer available

An Expanded Access Protocol for Sebelipase Alfa for Patients With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency
Alexion Pharmaceuticals

Terminated

A Study to Identify and Characterize LAL-D Patients in High-risk Populations

Lysosomal Acid Lipase Deficiency

United States
Azidus Brasil

Unknown

Evaluation of Pharmacokinetic and Pharmacodynamic Parameters of Somatropin Produced by Laboratory Blausiegel Indústria e Comércio Ltda., Compared to Saizen® From Laboratory Merck Serono S.A.

Growth Retardation | GH Deficiency (GHD)

Brazil
Azidus Brasil

Unknown

PHARMACODYNAMICS ASSESSMENT PRODUCT HEPARIN SODIUM (INTRAVENOUSLY) OF THE SWINE 5.000UI/ML OF BLAU FARMACÊUTICA S/A IN HEALTHY SUBJECTS IN COMPARISON OF SODIUM HEPARIN APP PHARMACEUTICALS

Healthy

Brazil
Inozyme Pharma

Not yet recruiting

ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency

Pseudoxanthoma Elasticum | Arterial Calcification | Gene Mutations | Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency | Autosomal Recessive Hypophosphatemic Rickets Type 2
The Dermatology Institute of Boston

Recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of Sarecycline for Treating Periorificial Dermatitis

Perioral Dermatitis

United States
University of Pennsylvania

Recruiting

Improving the Organizational Social Context to Address Structural Racism and Discrimination

HIV/AIDS

United States
Imperial College London

Not yet recruiting

Automated Insulin Delivery in Adults With Advanced Kidney Disease (AIDkidney)

Diabetes Mellitus | Chronic Kidney Diseases
Elizabeth Austen Lawson

Not yet recruiting

Identifying Oxytocin Deficiency in Adults With Pituitary Disease

Oxytocin Deficiency | Arginine Vasopressin Deficiency
Duke Street Bio Ltd

Not yet recruiting

Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies

Advanced Malignancies With Homologous Recombination Deficiency (HRD) (Breast, Ovarian, mCRPC, Brain Metastases)
German University in Cairo
Prof. Mohamed Hassan Solayman, Clinical pharmacy Department, German University... and other collaborators

Not yet recruiting

Effect of Vitamin D Supplementation on Mental Health: An Exploratory Study on A University Students Suffering From Vitamin D Deficiency

Psychiatric Disorder
University of Parma
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Federico II University; University... and other collaborators

Recruiting

Use of miRNAs in Growth Hormone Deficiency (GHD) (GH-miRNA2)

Growth Hormone Deficiency

Italy
Guiding Right, Inc.
University of California, San Diego

Recruiting

LinkPositively+ A Mobile Health App Delivered Intervention to Improve HIV Care Outcomes Among Black Women Affected by Mental Health and Violence (LPP Plus)

HIV/AIDS | Mental Health Issue

United States
South Tees Hospitals NHS Foundation Trust

Recruiting

Iron Deficiency in Acute Myocardial Infarction: Prevalence Pilot Study (IDAMI Pilot)

Acute Myocardial Infarction

United Kingdom
Claris Biotherapeutics, Inc.

Recruiting

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Limbal Stem Cell Deficiency

Limbal Stem Cell Deficiency

United States
Poznan University of Physical Education

Not yet recruiting

Relative Energy Deficiency in Rowers

Mood Disorders | Endothelial Dysfunction | Malnutrition, Calorie

Poland
Children's Hospital Medical Center, Cincinnati

Not yet recruiting

Vitamin A Supplementation in Allogeneic Stem Cell Transplantation.

Vitamin D Deficiency | Vitamin A Deficiency | Graft Vs Host Disease

United States
Assiut University

Not yet recruiting

Minerals Status in Relation to Overweight and Obese Adolescent

Mineral Deficiency

Egypt
London North West Healthcare NHS Trust

Not yet recruiting

PSYLIVED: the Psychological Impacts of Living With an Inherited Colorectal Cancer Predisposition Syndrome (PSYLIVED)

Lynch Syndrome | Polyposis Syndrome, Hereditary Mixed, 1 | Polyposis Syndrome, Hereditary Mixed, 2

United Kingdom
University of Milan
Kolfarma s.r.l. - Italy; Fondazione Telethon

Recruiting

Targeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD) (NUTRIENT)

CDKL5

Italy
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Primary Immunodeficiencies and Obstetrical Neuraxial Anaesthesia (ANEU-DIP)

Infectious Complications (Epidural Abscess or Meningitis) | Obstetrical Neuraxial Anaesthesia

France
Xuanwu Hospital, Beijing

Not yet recruiting

Efficacy and Safety Evaluation of Hyperthermic Baths in the Treatment of Seizures in Children With CDKL5 Deficiency

CDKL5 Deficiency Disorder

China
University Hospital, Montpellier

Not yet recruiting

Identification and Characterization of Circulating Tumor Cells Before and After Treatment (Surgery and Radiotherapy) in a Cohort of Patients Treated for Resectable Stage I-III Merkel Cell Carcinoma (MERCCALIBI)

Merkel Cell Carcinoma
University Hospital, Grenoble

Not yet recruiting

Brief Motivational Intervention (BMI) on the Deprescription of Benzodiazepines and Related Substances in Adult Chronic Drug Users (BENZ_HALTE)

Benzodiazepine Withdrawal

France
Cairo University

Not yet recruiting

Radiographic Assessment of Bone Gain Following Sinus Lifting With Simultaneous Implant Placement Using Crestal Approach With Membrane Control Technique for Bone Augmentation of Atrophied Maxillary Posterior Ridge

Implant Site Reaction | Maxillary Deficiency
University Ghent
Bill and Melinda Gates Foundation; Institut de Recherche en Sciences de la... and other collaborators

Recruiting

Adolescent Nutrition in Girls in Burkina Faso and Ethiopia (Adonut)

Nutrition Deficiency Due to Insufficient Food

Burkina Faso, Ethiopia
Assiut University

Recruiting

Effect of Bee-buzzy Vibrating Cold Application and Marionette Doll on Pain and Fear During Phlebotomy

Fear of Pain

Egypt
Assiut University

Not yet recruiting

Iron Status in Autism Spectrum Disorders

Anemia, Iron Deficiency
Seoul St. Mary's Hospital

Not yet recruiting

The Role of Intravenous Ferritin in Optimizing Postoperative Recovery Following Pancreaticoduodenectomy (Ferritin)

Pancreaticojuodenectomy
Assiut University

Not yet recruiting

Vitamin B12 Status and Its Impact on Chronic Haemodialysis Patient (Haemodialysis)

Vitamin B 12 Deficiency | End Stage Renal Disease on Dialysis
University Hospital, Montpellier
Université Montpellier; Centre National de la Recherche Scientifique, France

Not yet recruiting

Development of a New Family of HIV Latency Regulators (LRAs) Targeting the Tat Viral Protein (TatLat)

HIV Infections
Atlantic Health System
Regeneron Pharmaceuticals

Not yet recruiting

Atlantic Lipid Lowering Treatment Optimization Program (ALLTOP)

Familial Hypercholesterolemia | High Density Lipoprotein Deficiency | Lipoprotein Types--Lp System Lp(A) Hyperlipoproteinemia | Apolipoprotein B 100, Familial Defective | Low-Density-Lipoid-Type Hyperlipoproteinemia

United States
Xuanwu Hospital, Beijing

Not yet recruiting

Subiculum Electrical Stimulation for Temporal Lobe Epilepsy With Biliteral Hippocampus Sclerosis(SESTB)

Epilepsy, Drug Resistant

China
Gonzalo Blasi

Recruiting

The Influence of Non-Carious Cervical Lesions on Root Coverage

Gingival Recession

Spain

Search clinical trials for: LAL deficiency

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