Relative Energy Deficiency in Rowers

Relative Energy Deficiency in Females and Males Rowers - Observational Study

This study aims to learn about relative energy deficiency in male and female rowers at the end of the direct sport preparation phase of the annual training cycle. The main questions:

- How will energy intake influence leptin, cortisol levels, mood, gut discomfort, and permeability? The observational study involves male and female rowers from the Polish rowing team.

Participants will perform 2000 meter ergometer test and 6000 ergometer test in annual training cycle. Researchers will compare outcomes from both tests.

Study Overview

• Status: Not yet recruiting
• Conditions: Mood Disorders; Endothelial Dysfunction; Malnutrition, Calorie
• Intervention / Treatment: Other: 2000 meter ergometer test

• Study Type: Observational
• Enrollment (Estimated): 30

Contacts and Locations

• Study Contact: Name: Hanna Dziewiecka, Msc; Phone Number: 48 606880282; Email: hannadziewiecka@gmail.com
• Study Contact Backup: Name: Anna Skarpańska-Stejnborn, Profesor

Study Locations

• Poland
  • Lubuskie
    • Gorzów Wielkopolski, Lubuskie, Poland, 66-400
      • Poznan University of Physical Education, Faculty of Sport Sciences in Gorzow
      • Contact: Hanna Dziewiecka, Msc; Phone Number: 606880282; Email: hannadziewiecka@gmail.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Male rowers age 18 - 22 years.

Description

Inclusion Criteria:

• Membership in Polish Rowing Team,
• minimum five years of training,
• total training time minimum of 240 minutes,
• filling out a food diary,
• finishing 2000-meter ergometer test.

Exclusion Criteria:

• Probiotics within the last three months,
• prebiotics within the last three months
• antibiotic therapy within the last three months,
• dietary regime,
• gastrointestinal diseases.

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
male and female rowers; Rowers will perform 2000m ergometer test.A 2,000-m time trial is a standard test used to assess performance in rowers.	Other: 2000 meter ergometer test; Rowers will perform 2000m ergometer test. A 2,000-meter trial is a standard test used to assess performance in rowers.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
-FABP (intestinal fatty acid binding protein)to measure epithelial wall injury	I-FABP concentration measured in blood [ng/ml] using commercially availableenzyme-linked immunosorbent assays	Blood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting) up to one hour after getting up, 1 minute after the test, and 3-hour recovery period
Leptin to measure long-term energy balance	Leptin concentration measured in blood [ng/ml] using commercially availableenzyme-linked immunosorbent assays	Blood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting) up to one hour after getting up, 1 minute after the test, and 3-hour recovery period
Cortisol to measure stress	Stress hormone concentration measured in blood [ng/ml] using commercially available enzyme-linked immunosorbent assays	Blood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting) up to one hour after getting up, 1 minute after the test, and 3-hour recovery period
sCD14 multifunctional lipopolysaccharide receptor	sCD14 concentration measured in blood [ug/ml] using commercially available enzyme-linked immunosorbent assays	Blood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting) up to one hour after getting up, 1 minute after the test, and 3-hour recovery period
Claudin to measure tight junction leakage	Claudin concentration measured in blood [ng/ml] using commercially available enzyme-linked immunosorbent assays	Blood samples was taken from the cubital vein at three-time points: before each stress test (after overnight fasting) up to one hour after getting up, 1 minute after the test, and 3-hour recovery period
POMS	Profile of Mood States	day before the test
REST-Q sport	Recovery-Stress questionnaire for Athletes	day before the test

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
energy	energy [kcal ]of food intake measured by food diary	Time Frame: whole day (24hours) before test, in the morning before the test
protein	protein [g ]of food intake measured by food diary	Time Frame: whole day (24hours) before test, in the morning before the test
fat	fat [g ]of food intake measured by food diary	Time Frame: whole day (24hours) before test, in the morning before the test
carbohydrate	carbohydrate [g ]of food intake measured by food diary	Time Frame: whole day (24hours) before test, in the morning before the test
fiber	fiber [g ]of food intake measured by food diary	Time Frame: whole day (24hours) before test, in the morning before the test
Body mass	Body mass [kg] measured by electronic scale to the nearest 0,05 kg (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan)	in the morning before the test up to 1 hour after getting up
Body fat	Body fat [%] measured by electronic scale (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan)	in the morning before the test up to 1 hour after getting up
Total body water	Body water [%] measured by electronic scale (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan)	in the morning before the test up to 1 hour after getting up
Lean body mass	Lean body mass [kg] measured by electronic scale (Tanita BC 418 MA Tanita Corporation, Tokyo, Japan)	in the morning before the test up to 1 hour after getting up
Height	[cm] measured by high meter	in the morning before the test up to 1 hour after getting up
Self reported scale of gastrointestinal symptoms e.g.burping, heartburn, flatulence, abdominal pain, the urge to reiterate, vomiting, diarrhoea, nausea, dizziness, and stitch	10-point scale where 10 was the symptom with the greatest severity	up to 1 hours after the test

Collaborators and Investigators

• Sponsor: Poznan University of Physical Education
• Investigators: Study Director: Anna Skarpańska-Stejnborn, Profesor, Poznan University of Physical Education

Study record dates

Study Major Dates

• Study Start (Estimated): June 20, 2024
• Primary Completion (Estimated): June 26, 2024
• Study Completion (Estimated): June 30, 2024

Study Registration Dates

• First Submitted: June 5, 2024
• First Submitted That Met QC Criteria: June 10, 2024
• First Posted (Actual): June 11, 2024

Study Record Updates

• Last Update Posted (Actual): June 13, 2024
• Last Update Submitted That Met QC Criteria: June 11, 2024
• Last Verified: June 1, 2024

More Information

Terms related to this study

• Keywords: gut permeability; rowers; relative energy deficiency
• Additional Relevant MeSH Terms: Mental Disorders; Nutrition Disorders; Mood Disorders; Malnutrition
• Other Study ID Numbers: REDs2024

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No