Search clinical trials for: Meropenem

Total 192 results

Fundacion para la Investigacion Biomedica del Hospital...

Terminated

Approach for Optimizing Meropenem Therapy in Intubated and Mechanically-Ventilated, Adult Patients With Severe Gram-Negative Lower Respiratory Tract Infection (MON4STRAT)

Lower Respiratory Tract Infection

Belgium, Spain, France
Fundación Pública Andaluza para la gestión de la...

Unknown

Monitoring of Piperacillin-Tazobactam and Meropenem Plasmatic Levels in Critical Patients

Sepsis | Septic Shock

Spain
University Hospital Tuebingen

Withdrawn

Computer-based Dosage Calculation for Antibiotics

Acute Kidney Insufficiency | Anti-Infective Agent Toxicity

Germany
Karolinska University Hospital

Completed

Meropenem and Piperacillin Plasma Concentrations During CRRT (ABC2)

Sepsis | Hemolysis | Renal Replacement Therapy | Infection | Antibiotic

Sweden
Yonsei University

Completed

Population Pharmacokinetics of Teicoplanin, Levofloxacin, Piperacillin/Tazobactam, Meropenem, Vancomycin, Remifentanil, Cefepime, Cefpirome, Sufentanil, Midazolam, Clopidogrel, Ticagrelor, Prasugrel During Veno-arterial Extracorporeal Membrane Oxygenation (VA ECMO)

Cardiac Dysfunction

Korea, Republic of
Amsterdam UMC, location VUmc
ZonMw: The Netherlands Organisation for Health Research and Development; Fo...

Completed

Short Versus Extended Antibiotic Treatment With a Carbapenem for High-risk Febrile Neutropenia in Hematology Patients With FUO (SHORT)

Febrile Neutropenia | Hematological Malignancy

Netherlands
Venus Remedies Limited

Completed

CSE-1034 (Ceftriaxone+ Sulbactam+ EDTA) Compared to Meropenem in Complicated Urinary Tract Infections (cUTIs) Caused by ESBL Producing Gram Negative Bacteria (PLEA)

Acute Pyelonephritis | Urinary Tract Infection Complicated

India
Hannover Medical School

Unknown

Meropenem Pharmacokinetics in Spontaneous Bacterial Peritonitis

Liver Cirrhosis | Peritonitis Bacterial

Germany
Fundación Pública Andaluza para la gestión de la...
Spanish Network for Research in Infectious Diseases

Completed

Fosfomycin Versus Meropenem or Ceftriaxone in Bacteriemic Infections Caused by Multidrug Resistance in E.Coli (FOREST)

Infection Due to ESBL Escherichia Coli

Spain
Universiti Sains Malaysia

Unknown

Predictors and Outcomes of Meropenem Treatment Failure Among Patients With Septic Shock in Intensive Care Unit (Meropenem)

Predictors and Outcomes of Meropenem Treatment Failure
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

Dimethyl Fumarate, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Gliosarcoma | Adult Brain Glioblastoma

United States
Wei Zhao
Beijing Children's Hospital

Unknown

A Study the Population Pharmacokinetics of Children of Infectious Disease in Central Nervous System

Central Nervous System Infection

China
University of Aarhus

Completed

The Effect of Gut Sterilisation on Macrophage Activation in Patients With Alcoholic Hepatitis.

Alcoholic Hepatitis

Denmark
Shanghai 10th People's Hospital

Unknown

The Combined Antibiotic Therapy for Carbapenem Resistant Klebsiella Pneumoniae

Antibiotic Resistant Infection

China
Universidad del Norte

Unknown

Piperacillin/Tazobactam Versus Carbapenems in Non-bacteremic UTI Due to -ESBL-producing Enterobacteriaceae (CAPITIS)

Urinary Tract Infections | Enterobacteriaceae Infections | Clinical Trial | Carbapenem | Klebsiella Pneumoniae Infection | Infection Due to ESBL Bacteria | Escherichia Coli Infection | Drug Resistance, Bacterial

Colombia
Xiangya Hospital of Central South University

Unknown

Second-generation Sequencing Guides the Treatment of Severe Pneumonia (NGS)

Pneumonia | Metagenomic Next Generation Sequencing

China
Mahidol University

Completed

Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients

Sepsis | Critical Illness | Septic Shock | Morality | Pharmacokinetic | Carbapenem | Pharmacodynamic | Clinical Outcome | Organ Failure, Multiple

Thailand
Rempex (a wholly owned subsidiary of Melinta Therapeutics...
Department of Health and Human Services

Completed

Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults

Bacteremia | Acute Pyelonephritis | Ventilator-associated Bacterial Pneumonia | Urinary Tract Infection Complicated | Hospital Acquired Bacterial Pneumonia | Abdominal Infection

Italy, United States, Colombia, Greece, Israel, Brazil, Argentina, United Kingdom
Melinta Therapeutics, Inc.

Withdrawn

A Study of Meropenem-Vaborbactam Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia (TANGOIII)

Hospital-Acquired Bacterial Pneumonia | Ventilator-Associated Bacterial Pneumonia | Hospital-Acquired Pneumonia | Ventilator-Associated Pneumonia
Rempex (a wholly owned subsidiary of Melinta Therapeutics...
Biomedical Advanced Research and Development Authority

Completed

Evaluate Effects of Meropenem-Vaborbactam on QT/QTc in Healthy Volunteers

Healthy

United States
Cubist Pharmaceuticals LLC

Completed

Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Meropenem in Complicated Intraabdominal Infections

Complicated Intra-abdominal Infection

United States, Argentina, Israel, Bulgaria, Serbia, Korea, Republic of, Estonia, Chile, Hungary, Lithuania, Latvia, Croatia, Moldova, Republic of, Poland, Germany
Cubist Pharmaceuticals LLC

Completed

Safety and Efficacy Study to Compare IV CXA 101/Tazobactam and Metronidazole With Meropenem in Complicated Intraabdominal Infections

Complicated Intra-abdominal Infection

United States, Argentina, Serbia, Georgia, Russian Federation
University Hospital Hradec Kralove

Completed

Glycocalyx Damage and Beta-lactam Antibiotics in Surgical Critically Ill

Critical Illness

Czechia
Achaogen, Inc.
Department of Health and Human Services

Completed

A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE) (CARE)

Bloodstream Infections (BSI) Due to CRE | Hospital-Acquired Bacterial Pneumonia (HABP) Due to CRE | Ventilator-Associated Bacterial Pneumonia (VABP) Due to CRE | Complicated Urinary Tract Infection (cUTI) Due to CRE | Acute Pyelonephritis (AP) Due to CRE
TASK Applied Science
GlaxoSmithKline; Research Center Borstel; Eduardo Mondlane University; Barcelona...

Completed

Phase 2 Trial to Evaluate the Early Bactericidal Activity, Safety and Tolerability of Meropenem Plus Amoxycillin/CA and Faropenem Plus Amoxycillin/CA in Adult Patients With Newly Diagnosed Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
North Dakota State University
Neuropsychiatric Research Institute, Fargo, North Dakota

Terminated

Mechanistic Investigation Of Intestinal Cytochrome p450 3A4 Following Roux-en-Y Surgery And Its Effect on Plasma Concentrations of Buspirone

Gastric Bypass
Achaogen, Inc.

Completed

A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP) (EPIC)

Acute Pyelonephritis | Complicated Urinary Tract Infection
Beijing Children's Hospital
Hopital Universitaire Robert-Debre; Shandong University; Rennes University Hospital

Unknown

Population Pharmacokinetics of Meropenem and Linezolid in Children With Severe Infectious Diseases

Children；Infection

China
Pfizer

Completed

Evaluation of Safety,Pharmacokinetics and Efficacy of CAZ-AVI With Metronidazole in Children Aged 3 Months to 18 Years Old With Complicated Intra-abdominal Infections (cIAIs).

Complicated Intra-abdominal Infections

Spain, Taiwan, United States, Poland, Hungary, Czechia, Turkey, Greece, Romania, Russian Federation
Nourhan Hassan Osama Thuraya Mohamed
Ain Shams University

Completed

The Effect of Colistin Inhalation on Ventilator Associated Pneumonia

Ventilator Associated Pneumonia
Loyola University

Terminated

Efficacy of Oral Antibiotic Therapy Compared to Intravenous Antibiotic Therapy for Osteomyelitis (CRO-OSTEO)

Osteomyelitis

United States
Centre Hospitalier Universitaire de Besancon

Unknown

PK/PD of Extended-infusion Meropenem, Piperacillin-tazobactam and Cefepime in the Early Phase of Septic Shock (PAACS)

Septic Shock

France
Pfizer

Completed

Prospective Multicenter Doubleblind Randomized Study of NXL104/Ceftazidime + Metronidazole vs. Meropenem in Treatment of Complicated Intra-abdominal Infections

Complicated Intra-abdominal Infections

United States, Lebanon, France, Romania, Bulgaria, India, Poland, Russian Federation
University of Pittsburgh

Completed

Resistance Rates and Mechanisms of Resistance to Imipenem and Meropenem at UPMC

Gram Negative Organism

United States
Melinta Therapeutics, Inc.
Department of Health and Human Services

Completed

Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP

Acute Pyelonephritis | Urinary Tract Infection Complicated

Italy, Spain, Greece, Peru, United States, Bulgaria, Slovenia, Hungary, Romania, Brazil, Slovakia, Czechia, Ukraine, Taiwan, Belarus, Poland, Korea, Republic of
Hoffmann-La Roche

Completed

A Study to Investigate the Pharmacokinetics of RO7079901 and Meropenem in Participants With a Complicated Urinary Tract Infection

Urinary Tract Infections

United States, Serbia, Hungary, Latvia, Poland
Hoffmann-La Roche

Completed

A Study to Investigate the Intrapulmonary Lung Penetration of Nacubactam in Healthy Participants

Gram-negative Bacterial Infections

United States
Joseph Kuti
Thrasher Research Fund

Completed

Population Pharmacokinetics of Prolonged Infusion Meropenem in Cystic Fibrosis (CF) Children

Pneumonia | Cystic Fibrosis | Pseudomonas Aeruginosa Infection

United States
Institute of Liver and Biliary Sciences, India

Terminated

To Study the Influence of GCSF on Natural History of Acute On Chronic Liver Failure After the Acute Phase

Acute on Chronic Liver Failure

India
GlaxoSmithKline

Terminated

GSK2251052 in the Treatment of Complicated Intra-abdominal Infections

Infections, Intestinal

United States, Czechia, Russian Federation, Spain, Canada, France, Italy
The University of Queensland
Australasian Society for Infectious Diseases; International Society of Chemotherapy and other collaborators

Terminated

RCT Meropenem vs Piperacillin-Tazobactam for Definitive Treatment of BSI's Due to Ceftriaxone Non-susceptible Escherichia Coli and Klebsiella Spp. (MERINO)

Bloodstream Infections

Australia, Singapore, South Africa, Italy, Saudi Arabia, Canada, Lebanon, New Zealand, Turkey
University of Florida

Terminated

Clinical Trials to Reduce the Risk of Antimicrobial Resistance

Bacterial Pneumonia

United States, Spain, France, Germany
Pfizer
Forest Laboratories

Completed

Compare Ceftazidime-Avibactam + Metronidazole Versus Meropenem for Hospitalized Adults With Complicated Intra-Abdominal Infections

Complicated Intra-Abdominal Infection

United States, Croatia, Bulgaria, Peru, Russian Federation, Latvia, Ukraine, Mexico, Romania, South Africa, Argentina, Czechia, Hungary, Israel, Taiwan, India, Thailand, Spain, Netherlands, Malaysia
Pfizer

Completed

Compare Ceftazidime-Avibactam + Metronidazole vs Meropenem for Hospitalized Adults With Complicated Intra-Abd Infections (RECLAIM3)

Complicated Intra-abdominal Infection

Korea, Republic of, Vietnam, China
Pfizer

Completed

A Study Comparing Ceftazidime-Avibactam Versus Meropenem in Hospitalized Adults With Nosocomial Pneumonia

Ventilator-associated Pneumonia (VAP) | Nosocomial Pneumonia (NP)

Bulgaria, France, Italy, Korea, Republic of, Mexico, Peru, Poland, Russian Federation, Spain, Turkey, United Kingdom, Vietnam, Philippines, China, Ukraine, Argentina, Brazil, Hungary, Romania, India, Japan, Taiwan, Latvia, Czechia, Slov... and more
Pfizer

Completed

A Study to Determine if Antibiotics Prevent Infection in the Pancreas of Patients Where Part of the Pancreas Has Died

Pancreatitis, Acute Necrotizing

United States, Canada
Pfizer

Completed

Complicated Skin and Skin Structure Infections

Abscess | Cellulitis | Skin Infection
Pfizer

Completed

Ventilator-Associated Pneumonia/Hospital-Acquired Pneumonia Requiring Mechanical Ventilatory Support

Pneumonia

United States
Pfizer

Completed

Pharmacoeconomic Analysis of First Line Meropenem Versus Standard Antibiotic Treatment in Seriously Infected Secondary Nosocomial Sepsis Syndrome Patients.

Sepsis

Hungary
Pfizer

Completed

Evaluation of Pancreatic Tissue Penetration of Meronem® in the Prophylaxis of Septic Complications in Severe Pancreatitis

Pancreatitis

Colombia

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