Search clinical trials for: Midazolam

Total 1156 results

Food and Drug Administration (FDA)
Leiden University; Spaulding Clinical Research LLC

Completed

Clinical Study to Investigate the Effect of the Combination of Psychotropic Drugs and an Opioid on Ventilation

Hypercapnia | Ventilatory Depression

United States
Indivior Inc.

Completed

Study of Potential CYP3A4 Induction by INDV-2000 in Healthy Adults

Healthy

United States
Benha University

Completed

Buccal Midazolam Versus Intranasal Dexmedetomidine Plus Oral Chloral Hydrate in Inguinal Hernia Repair

Inguinal Hernia Repair

Egypt
Columbia University
Emergency Medicine Foundation; Mailman School of Public Health

Completed

Dose-Finding Study of Intranasal Midazolam for Procedural Sedation in Children

Procedural Anxiety

United States
MemorialCare Health System
Memorial Medical Center Foundation

Completed

Pilot Study on Pairing Sedation Strategies and Weaning

Acute Respiratory Failure

United States
Boehringer Ingelheim

Completed

A Study to Test How Well Different Doses of BI 1584862 Are Tolerated by Healthy Men

Healthy

Germany
Amgen

Active, not recruiting

A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100)

KRAS p.G12C Mutant Advanced Solid Tumors

United States, France, Canada, Spain, Belgium, Korea, Republic of, Austria, Australia, Hungary, Greece, Germany, Japan, Romania, Switzerland, Brazil, Portugal
Mirati Therapeutics Inc.

Completed

PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates

Advanced Solid Tumor

United States
Unity Health Toronto
Unity Health Toronto

Completed

Sustained Mood Improvement With Laughing Gas Exposure: A Randomized Controlled Pilot Trial (SMILE)

Major Depressive Disorder | Treatment Resistant Depression

Canada
University Hospital Bispebjerg and Frederiksberg

Completed

Metabolism of Chlordiazepoxide in the Treatment of Alcohol Withdrawal Symptoms

Alcohol Withdrawal

Denmark
Janssen Research & Development, LLC

Active, not recruiting

An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer

Urothelial Cancer

United States, France, Germany, United Kingdom, Belgium, Taiwan, Spain, Israel, India, Romania, Korea, Republic of, Russian Federation, Turkey, Austria, Moldova, Republic of
Unity Health Toronto

Enrolling by invitation

SMILE Trial - Imaging Sub-Study

Major Depressive Disorder

Canada
Amgen

Active, not recruiting

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 1 Dose Escalation Study of VX-973 in Healthy Adults

Pain

United Kingdom
Hospital for Special Surgery, New York

Completed

Audiovisual Aid Pilot Study

Stress, Psychological

United States
Cukurova University

Completed

Preoperative Anxiolysis With Intravenous Midazolam on Intraoperative Sevoflurane Gas Consumption

Sevoflurane | Midazolam

Turkey
VA Office of Research and Development
Mayo Clinic; University of Minnesota

Completed

Efficacy of Repeated Ketamine Infusions for Treatment-resistant Depression

Treatment-resistant Depression

United States
Blueprint Medicines Corporation

Completed

A Drug-drug Interaction Study of Avapritinib and Midazolam

Gastrointestinal Stromal Tumors | GIST | Non-resectable Advanced Solid Tumors | Recurrent or Unresectable Central Nervous System (CNS) Tumors

United States
Kancera AB
LINK Medical Research AB; CRST Oy; Q&Q Labs AB

Completed

Evaluation of Safety, Tolerability, Pharmacokinetics, Food Effect and Interaction With Midazolam in Healthy Volunteers After Oral Single and Multiple Ascending Dosing of KAND145

Ovarian Cancer

Finland
Pfizer

Completed

A Study to Learn About the Drug-drug Interactions of Sisunatovir in Healthy Adult Participants

Respiratory Syncytial Virus Infections

United Kingdom
Boehringer Ingelheim

Active, not recruiting

A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation

Solid Tumors, KRAS Mutation

Spain, United Kingdom, United States, Belgium
Janssen Research & Development, LLC

Completed

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide

Depressive Disorder, Major

United States, France, Italy, Spain, Hungary, Belgium, Brazil, Bulgaria, Poland
Guangdong Raynovent Biotech Co., Ltd

Completed

Drug-durg Interaction of Leritrelvir(RAY1216) With Midazolam, Omeprazole, Rosuvastatin, Verapamil, and Rifampin

Drug Drug Interaction

China
Greg S Cohen MD LLC

Completed

Sedation Regimens in GI Endoscopy

Anesthesia | Endoscopy | Colonoscopy | Conscious Sedation

United States
Millennium Pharmaceuticals, Inc.

Completed

Drug-Drug Interaction Study of TAK-788 and Midazolam in Participants With Advanced Non-small Cell Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

Australia, Singapore, Netherlands
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of Danicamtiv on the Drug Levels of Midazolam in Participants With Stable Heart Failure

Heart Failure With Reduced Ejection Fraction

United States
Sinno H.P. Simons
Radboud University Medical Center; ZonMw: The Netherlands Organisation for... and other collaborators

Completed

Population PK/PD of Off Label Drugs in Premature Neonates (DINO)

Premature Birth

Netherlands
Pfizer

Terminated

A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement

Carcinoma, Non-Small-Cell Lung | Brain Neoplasms | Malignant Melanoma | Brain Neoplasms, Primary | Malignant Neoplasms

United States, Canada, Israel
Centre Hospitalier Intercommunal de Toulon La Seyne...

Completed

Sodium Oxybate Versus Midazolam for Comfort Sedation (ONAMI)

Palliative Care

Monaco
Kaken Pharmaceutical

Active, not recruiting

A Study to Determine the Effect of KP-001 on Metformin and Midazolam Pharmacokinetics and the Effect of Clarithromycin on KP-001 Pharmacokinetics in Healthy Adult Participants

Healthy Adults

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Pharmacokinetic Drug-drug Interactions Between VX-548, Midazolam, and Digoxin

Pain

United States
University of Washington

Active, not recruiting

Effect of Testosterone Treatment on Drug Metabolism and Transport

Transgender Persons

United States
National Cancer Institute, Egypt

Completed

Intrathecal Dexmedetomidine vs Midazolame

Postoperative Pain

Egypt
Mahidol University

Completed

Effectiveness of Ketamine Treatment for Three Consecutive Days in Depression

Depression

Thailand
University of Alabama at Birmingham

Active, not recruiting

Effect of Sedation on Cognitive Performance in the Elderly

Postoperative Cognitive Dysfunction

United States
Boehringer Ingelheim

Completed

A Study in Healthy Men and Women Who Are Either Between 18 - 45 Years or Between 65 - 80 Years to Test How Different Doses of BI 474121 Are Tolerated

Healthy

Germany
University of Liege

Completed

Virtual Reality Hypnosis in Total Knee Arthroplasty Under Spinal Anesthesia

Knee Osteoarthritis | Arthroplasty Complications | Sedation Complication | Anesthesia Complication | Hypnotic; Anxiety Disorder

Belgium
University of Liege

Completed

Impact of Virtual Reality Hypno-sedation on Functional Recovery and Anxiety in Foot Surgery With Regional Anesthesia

Analgesia | Foot Deformities | Regional Anesthesia Morbidity | Valgus; Hallux

Belgium
Jiangsu HengRui Medicine Co., Ltd.

Completed

PK Effects of SHR4640 on Repaglinide and Midazolam, and the Impact of SHR4640 on QT Interval

Gout and Hyperuricemia

China
Alexandria University

Active, not recruiting

Effects on Recovery of Children of Intravenous Formulation of Fentanyl Citrate and Midazolam Orally for Premedication

Separation Anxiety

Egypt
EpiEndo Pharmaceuticals
CTC Clinical Trial Consultants AB

Completed

Clinical Trial to Assess Effect of Verapamil on Systemic Exposure of EP395 and Effect of EP395 on Systemic Exposure of Midazolam and Digoxin

COPD | Chronic Obstructive Pulmonary Disease Exacerbation

Sweden
University of California, Irvine

Completed

Adjunct Sedatives in Endoscopic Ultrasound (EUS) and Endoscopic Retrograde Cholangiopancreatography (ERCP) Procedures

Endoscopic Retrograde Cholangiopancreatography (ERCP) | Endoscopic Ultrasound (EUS)

United States
Arooj Khan

Completed

Intramuscular Midazolam Versus Intravenous Diazepam for Acute Seizure in Children

Seizures

Pakistan
Stanford University

Withdrawn

Ketamine and Midazolam Infusions for CRPS: Feasibility Study

Complex Regional Pain Syndromes

United States
Boehringer Ingelheim

Completed

A Study in Healthy Men and Women to Test How Well Different Doses of BI 1323495 Are Tolerated

Healthy

Germany
Assiut University

Completed

Sedation During Spinal Anesthesia

Sedation During Spinal Anesthesia

Egypt
Boehringer Ingelheim

Completed

A Study to Test How Healthy Men Tolerate Different Doses of BI 1595043

Healthy

Belgium
Mansoura University

Completed

Bispectral Index Monitoring In Pediatric Cataract Surgery: A Comparative Study Using Propofol-Midazolam Versus Sevoflurane Anesthesia

Ophthalmic

Egypt
Rush University Medical Center

Active, not recruiting

Safety of Driving After Minor Surgery With Monitored Anesthesia Care (MACDrive)

Minor Surgical Procedures With Monitored Anesthesia Care | Driving Performance After Minor Ambulatory Surgery

United States
Arcus Biosciences, Inc.

Completed

Study to Investigate the Safety, Tolerability, and Pharmacokinetic Profile With Oral AB521 in Healthy Volunteers (ARC-14)

Healthy Participants

Netherlands

Search clinical trials for: Midazolam

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