Search clinical trials for: Moderate to severe mouth pain

Total 475206 results

EMS

Not yet recruiting

Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars (ALIV)

Moderate Pain | Severe Pain
Unither Pharmaceuticals, France
EXCELYA Bordeaux

Completed

Nefopam/Paracetamol Fixed Dose Combination in Acute Pain After Impacted Third Molar Extraction

Acute Pain

France, Russian Federation, Belgium, Hungary, United Kingdom
Bayer

Completed

Study to Collect Information on How Well the Study Drug Naproxen Sodium Tablets Works Compared to Hydrocodone/Acetaminophen Tablets in Order to Relieve Pain in Participants Experiencing Moderate to Severe Pain After Having Their Wisdom Teeth Removed

Pain

United States
Bayer

Completed

Study to Find Out the Optimal Dose of Caffeine in the Combination Tablet of Naproxen Sodium and Caffeine in Patients Experiencing Moderate to Severe Pain After Having Wisdom Teeth Removed

Pain, Postoperative

United States
Hospital de Clinicas de Porto Alegre

Completed

Cheeks Appearance as a Novel Predictor of Obstructive Sleep Apnea The CASA Score Study (CASA)

Muscle Weakness | Obstructive Sleep Apnea | Swallowing Disorder | Muscle Disorder | Face | Breathing, Sleep-Disordered

Brazil
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of HR18042 Tablets in the Treatment of Postoperative Pain of Impacted Tooth.

Moderate to Severe Acute Pain

China
Menarini Group

Completed

Tramadol Hydrochloride and Dexketoprofen Trometamol for the Oral Treatment of Moderate to Severe Acute Pain Following Removal of Impacted Lower Third Molar (DAVID)

Acute Pain

Italy, Hungary, Spain, Poland, United Kingdom
Mundipharma Research Limited

Terminated

A Study to Characterize the Pharmacokinetics and Tolerability of Buprenorphine Patches in Children With Moderate to Severe Mouth Pain (BUP1501)

Chemotherapy Induced Mucositis | Mouth Pain

Denmark, United Kingdom
Sun Yat-sen University

Unknown

Comparison of Oxycodone to Control Moderate or Severe Oral Mucositis Pain Induced by Chemoradiotherapy

Nasopharyngeal Carcinoma

China
Novartis Pharmaceuticals

Completed

A Study to Assess the Efficacy and Tolerability of Diclofenac Potassium Soft Gelatin Capsules Compared With Ibuprofen Tablets in Patients With Moderate to Severe Postoperative Dental Pain

Post Operative Dental Pain

United States
Menarini Group
PRA Health Sciences

Completed

Analgesic Effect of Different Combinations of Dexketoprofen Trometamol With Tramadol Hydrochloride in a Model of Moderate to Severe Pain (DEX-TRA 02)

Pain

Spain, Germany, Hungary, Italy, Poland, United Kingdom
Haisco Pharmaceutical Group Co., Ltd.

Not yet recruiting

Efficacy and Safety of HSK16149 Capsule in the Treatment of Moderate and Severe Central Neuropathic Pain in China

Central Neuropathic Pain
Tufts University
Colgate Palmolive

Not yet recruiting

Dry Mouth Toothpaste Study - Comparing Two Toothpastes With Arginine

Xerostomia

United States
Mesoblast, Ltd.

Not yet recruiting

Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back Pain (HyaluronicAcid)

Degenerative Disc Disease
The Fourth Affiliated Hospital of Zhejiang University...

Not yet recruiting

Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery

Postoperative Pain
The Second Affiliated Hospital of Chongqing Medical...
The First Affiliated Hospital of Zhengzhou University; ChongGang General Hospital and other collaborators

Recruiting

Effect of Noise Isolation on the Incidence of Moderate to Severe Postoperative Pain

Postoperative Pain

China
UNICEF - Venezuela

Recruiting

Treatment of Acute Malnutrition in Outpatient Care Services in Venezuela: a Prospective Cohort Research

Wasting | Acute Malnutrition in Childhood | Child Malnutrition

Venezuela
Amgen

Recruiting

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

Sjögren's Syndrome (SS)

United States
Amgen

Recruiting

A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

Sjogren's Syndrome

Israel, Chile, United States, Argentina, Canada, Japan, Korea, Republic of
Merz Therapeutics GmbH

Recruiting

A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve Injury (PaiNT)

Moderate to Severe Chronic Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN) or Peripheral Nerve Injury

Bulgaria, Germany, Poland, France, Hungary, Spain
Nanjing Chia-tai Tianqing Pharmaceutical

Recruiting

A Clinical Trial to Evaluate Efficacy and Safety of Elagolix Tablets in Women With Moderate or Severe Endometriosis-associated Pain

Endometriosis

China
Cara Therapeutics, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica

Pruritus | Notalgia Paresthetica

United States, Poland, Spain, Canada, Germany
Henan Cancer Hospital

Recruiting

Real World Study of Oxycodone Sustained-release Tablets for Patients With Moderate to Severe Cancer Pain

Cancer Pain | Oxycodone | Real-world Study

China
Bio Genuine (Shanghai) Biotech Co., Ltd.

Recruiting

Efficacy and Safety of BG2109 in Chinese Subjects With Endometriosis

Endometriosis | Moderate to Severe Endometriosis-associated Pain

China
Proteocyte Diagnostics Inc.
The University of Texas Health Science Center, Houston; University of Alabama... and other collaborators

Recruiting

Evaluation of Oral Potentially Malignant Disorders (OPMDs) With STRATICYTE™

Mouth Diseases

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

BiPAP in Pediatric Moderate to Severe Asthma Randomized Control Trial

Asthma in Children

United States
Stephen Robert Marder

Not yet recruiting

MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder

Post Traumatic Stress Disorder

United States
Koite Health Oy
Lithuanian University of Health Sciences; University of Helsinki

Recruiting

Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis

Periodontitis Chronic Generalized Moderate | Periodontitis Chronic Generalized Severe

Lithuania
Taipei Medical University Hospital

Recruiting

Effects of Multiple Mega-dose of Vitamin D3 Supplementation on Ameliorating Moderate to Severe Chronic Pain in Hemodialysis Patients

Hyperparathyroidism | Chronic Pain | Hemodialysis

Taiwan
Qilu Pharmaceutical (Hainan) Co., Ltd.

Recruiting

A Study to Evaluate Safety and Efficacy of Elagolix in Patients With Moderate to Severe Endometriosis-Associated Pain

Endometriosis

China
Guangdong Second Provincial General Hospital

Recruiting

Construction of Perioperative Medical Data Platform and Its Typical Practice to Predict Postoperative Acute Moderate to Severe Pain With Machine Learning Models

Acute Pain | Anesthesia | Risk Reduction

China
Organon and Co
Iqvia Pty Ltd

Recruiting

A Study to Investigate Efficacy and Safety of OG-6219 BID in 3 Dose Levels Compared With Placebo in Participants Aged 18 to 49 With Moderate to Severe Endometriosis-related Pain (ELENA)

Endometriosis

United States, Hungary, Poland, France, Germany, Czechia, Belgium, Bulgaria, Italy, Latvia
Spine BioPharma, Inc
MCRA

Recruiting

Moderate - Severe Degenerative Disc Disease Evaluation of the Lumbar Spine (MODEL)

Lumbar Degenerative Disc Disease

United States
Pharmbio Korea Co., Ltd.

Recruiting

Study of PBK_L1704 for the Treatment of Moderate to Severe Acute Pain After Bunionectomy in South Korea

Acute Pain

Korea, Republic of
Q32 Bio Inc.

Recruiting

Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)

Atopic Dermatitis

United States
Changhai Hospital
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University and other collaborators

Not yet recruiting

Magnetically Controlled Capsule Endoscope System in Stomach Examination of Moderately and Severely Obese Patients

Obesity

China
Nadja Naenni

Recruiting

The Adjunctive Effect of Soft Tissue Augmentation Procedures of Moderate-severe Peri-implantitis

Peri-Implantitis

Germany, Singapore, Switzerland
NEMA Research, Inc.

Recruiting

Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy

Pain, Postoperative

United States
3D Medicines

Not yet recruiting

3D1002 in Combination With Oxycodone Hydrochloride Sustained-release Tablets in Patients With Moderate to Severe Cancer Pain

Cancer Pain
Xinhua Hospital, Shanghai Jiao Tong University...

Recruiting

Effects of Virtual Reality (VR) Based Distraction and Relaxation Therapy on Moderate and Severe Pain

Pain

China
Shivank Bhatia

Recruiting

Effectiveness and Safety of Embosphere Microspheres for Embolization of the Geniculate Artery for the Treatment of Pain With Known Moderate to Severe Knee Osteoarthritis

Knee Osteoarthritis

United States
Eurofarma Laboratorios S.A.

Recruiting

Fixed Dose Combination of COdeine + DIpyrone to Mitigate Moderate to Intense Pain Post-impacted Third Lower Molar Extraction (CODI)

Pain

Brazil
Proteocyte Diagnostics Inc.

Recruiting

Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment

Oral Neoplasm

Canada
AbbVie

Recruiting

Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain

Endometriosis

United States, Puerto Rico
LEO Pharma

Recruiting

Adjusted Brodalumab Dose Compared With Standard Brodalumab Dose in Subjects With Moderate-to-severe Plaque Psoriasis and ≥120 kg Body Weight (ADJUST)

Psoriasis Vulgaris

Belgium, Italy, Spain, Germany, Czechia, Greece, United Kingdom, France, Hungary, Poland, Netherlands
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Recruiting

A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease (CULTIVATE)

Crohn's Disease

United States, Korea, Republic of, Netherlands, Colombia, Israel, Italy, Lebanon, Mexico, Poland, Spain, Turkey, Australia, Georgia, Czechia, Belgium, Germany, South Africa, Greece, Russian Federation, United Kingdom, Croatia, Serbia and more
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Recruiting

An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis (ELEVATE UC OLE)

Ulcerative Colitis

Poland, Japan, Georgia, Estonia, United States, Czechia, Australia, Korea, Republic of, Lithuania, Italy, Hungary, Turkey, Spain, Romania, Serbia, Germany, France, Bulgaria, Austria, Belarus, Canada, Croatia, Denmark, Israel, Latvia, Lebanon and more
Apeptico Forschung und Entwicklung GmbH

Recruiting

Safety and Preliminary Efficacy of Sequential Multiple Ascending Doses of Solnatide to Treat Pulmonary Permeability Oedema in Patients With Moderate-to-severe ARDS

ARDS

Austria, Germany
Celgene

Recruiting

An Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

Crohn Disease

United States, Argentina, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Canada, Chile, Croatia, Czechia, Denmark, Finland, France, Germany, Ireland, Israel, Italy, Korea, Republic of, Latvia, Mexico, Moldova, Republic of, ... and more
Celgene

Recruiting

A Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

Crohn Disease

United States, Argentina, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Canada, Croatia, Czechia, Denmark, Finland, France, Germany, Ireland, Israel, Italy, Korea, Republic of, Latvia, Mexico, Moldova, Republic of, Poland, Romani... and more

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